Clinical trials: Right Heart Catheterisation
Cardiac Surgical Procedures, Central Venous Catheterization
Dynamic SAX vs Conventional LAX in Internal Jugular Vein Catheterization
Conventionally, short-axis out-of-plane (SAX) or long-axis in-plane (LAX) ultrasound views are commonly used to guide internal jugular vein catheterization.
- Conditions
- Cardiac Surgical Procedures, Central Venous Catheterization, Ultrasonography
- Trial name
- NCT03841968
- Testing
- Dynamic needle tip positioning under ultrasound-guidance, Conventional long-axis view
- Where
- South Korea
- Volunteers
- 146 people
- Sponsor
- Seoul National University Hospital
Chronic Thromboembolic Pulmonary Hypertension, Residual Pulmonary Hypertension
Continuous Remote Haemodynamic Monitoring With CardioMEMS™ Following Pulmonary Endarterectomy in Chronic Thromboembolic Pulmonary Hypertension:
Chronic thromboembolic pulmonary hypertension (CTEPH) is potentially curable by pulmonary endarterectomy (PEA), although a substantial proportion of patients develop residual pulmonary hypertension despite successful surgery.
- Trial name
- CARDIOMEMSCTPH (NCT07758179)
- Testing
- CardioMEMS
- Volunteers
- 30 people
- Sponsor
- Hospital Universitario 12 de Octubre
Cardiovascular Disease
Left vs. Right Radial Approach for Routine Catheterization of Heart Transplant Patients
Orthotopic heart transplantation is a well established therapeutic measure for end stage heart failure, leading to significant improvements in survival and quality of life.
- Trial name
- NCT02163031
- Testing
- devices used in the coronary angiography
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital Clinic of Barcelona
Multidetector Computed Tomography, Pulmonary Embolism and Thrombosis
Lung Perfusion Measured With Dual-Energy CT in Patients With Chronic Thromboembolic Pulmonary Hypertension: Comparative Study With Right Heart Catheterization and V/Q
A comparative, observational, cross-sectional and prolective diagnostic test study, including patients that have had a right heart catheterization and were referred for a CT pulmonary angiography as part of their imaging workup…
- Conditions
- Multidetector Computed Tomography, Pulmonary Embolism and Thrombosis, Hypertension Pulmonary Secondary
- Trial name
- NCT03450304
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Congestive Heart Failure
Study to Evaluate Cardiac Hemodynamics and Safety of SLV320 in Subjects With Congestive Heart Failure
The study is a randomized, placebo controlled, multi-center, single dose study to evaluate cardiac hemodynamics and safety of iv SLV320 in 110 subjects with congestive heart failure requiring diuretic treatment.
- Trial name
- NCT00160134
- Testing
- SLV320
- Where
- Germany
- Sponsor
- Solvay Pharmaceuticals
Pulmonary Hypertension, Pulmonary Embolism (Diagnosis)
China Pulmonary Vascular Disease Intervention Diagnosis and Management Study-right Heart Catheterization
Right heart catheterization(RHC) plays a crucial role in the diagnosis and treatment of pulmonary vascular diseases(PVD). In China, the lack of equipment and technical expertise has historically limited the implementation of RHC…
- Conditions
- Pulmonary Hypertension, Pulmonary Embolism (Diagnosis), Pulmonary Arterial Hypertension, Right Heart Catheterization
- Trial name
- CHA-RHC (NCT06954727)
- Testing
- No intervention; Observational study
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- China-Japan Friendship Hospital
Caridovascular Disease, Congenital Heart Disease
Real-time MRI Right Heart Catheterization Using Passive Catheters
Background: Currently, heart catheterization procedures are guided by X-rays. Researchers are developing new techniques to perform heart catheterization without the use of X-rays by investigating possible uses of magnetic…
- Conditions
- Caridovascular Disease, Congenital Heart Disease, Pulmonary Hypertension
- Trial name
- NCT01287026
- Testing
- Cardiac Real-time MRI RHC (Right Heart Catheterization)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Heart Failure, Pulmonary Hypertension
Mechanisms of Pulmonary Vascular Dysfunction in Heart Failure
Heart failure (HF) patients often develop pulmonary hypertension (PH) that leads to transition into a biventricular HF with poor prognosis.
- Conditions
- Heart Failure, Pulmonary Hypertension, Pulmonary Vascular Resistance Abnormality
- Trial name
- LUNG-HF (NCT06331208)
- Testing
- non-contrast chest CT, spirometry with diffusing lung capacity for carbon monoxide (DLCO) analysis, Omics analysis of blood plasma obtained from pulmonary artery or peripheral blood
- Where
- Czechia
- Volunteers
- 230 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Heart Failure, Photoplethysmography
Seerlinq: Non-invasive LVFP Monitoring in HF
Left ventricular filling pressure (LVFP) monitoring has been associated with improved quality of life, survival and reduced hospitalization rates.
- Conditions
- Heart Failure, Photoplethysmography, Right Heart Catheterization
- Trial name
- PPG-HF (NCT06649435)
- Testing
- PPG measurement
- Where
- Slovakia
- Volunteers
- 131 people
- Sponsor
- Seerlinq s. r. o.
Radiation Exposure, Radiation Exposure to Operator
Operator Radiation Dose Using Ultra-Low Fluoroscopic Pulse Rate Versus Standard In Performing Coronary Angiography Via Right Radial Artery
The goal of this randomized clinical trial is to determine if there can be reduction in the radiation exposure to the cardiologist performing a coronary angiogram via a right radial artery approach by using a lower fluoroscopic…
- Trial name
- NCT07221175
- Testing
- Ultra low dose fluoroscopic pulse rate, Standard low dose fluoroscopic pulse rate
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Maimonides Medical Center
Right Heart Catheterization
The Nanowear Wearable System SimpleSense Validation Trial for Cardiac Output
The Nanowear SimpleSense study is a single center, prospective, non-randomized, feasibility, non- significant risk study The study will be done in 2 phases.
- Trial name
- NCT05629533
- Testing
- SimpleSense
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Nanowear Inc.
Hypertension, Pulmonary
The Role of Echocardiographic Contrast (Optison) in Enhancing Tricuspid Regurgitation Spectral Doppler Signals
The investigators aim to correlate noninvasive pulmonary artery systolic pressure (PASP) measurements obtained with and without echocardiographic contrast (Optison) during transthoracic echocardiography (TTE) with those obtained…
- Trial name
- NCT02560116
- Where
- United States
- Sponsor
- Northwell Health
Complex Congenital Heart Disease, Chronic Right Heart Failure
Magnetic Sensor Validation of Hemodynamic Non-invasive Measurements Pressure During Cardiac Catheterization
Follow-up of patients with complex congenital heart disease (CHD) usually involves ultrasound imaging or even MRI or CT scans of the heart and stress testing.
- Trial name
- CapMag (NCT05943275)
- Testing
- Magnetic sensor
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Montpellier
Pulmonary Hypertension
Investigation of H01 in Adults With Pulmonary Hypertension Including Interstitial Lung Disease (The SATURN Study).
This study is a prospective, randomized, double-blind, study of H01 (Hymecromone) in adults with pulmonary hypertension (PH). The primary objective of this study is to evaluate the safety and tolerability of oral H01 and the…
- Trial name
- SATURN (NCT05128929)
- Testing
- Hymecromone (H01)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Stanford University
Exercise Tolerance, Dyspnea
Study of Exercise and Heart Function in Patients With Heart Failure and Pulmonary Vascular Disease
Heart Failure with Preserved Ejection Fraction (HFpEF) and Pulmonary Hypertension (PH) can be diagnosed noninvasively by Exercise Echocardiography (ExE) and Cardiopulmonary Exercise Testing (CPX) as compared with gold standard…
- Conditions
- Exercise Tolerance, Dyspnea, Heart Failure, Pulmonary Hypertension
- Trial name
- EXEC (NCT01418248)
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Mayo Clinic
Pulmonary Embolism (Diagnosis)
Inorganic Nitrates in Intermediate High-risk Pulmonary Embolism
Pulmonary embolism (PE) is a serious condition caused by blood clots blocking the blood vessels in the lungs. In some patients, PE leads to increased pressure in the lung circulation and strain on the right side of the heart.
- Trial name
- NITRATE-PE (NCT07431229)
- Where
- 2 sites in Sweden
- Volunteers
- 36 people
- Sponsor
- Karolinska Institutet
Sedation and Analgesia
a Comparive Study of Ketamine-Propofol Versus Dexmedetomidine-Propofol Sedation in Pediatric Patients Undergoing Cardiac Catheterization for Device Closure of Simple Left-to-right Shunts
This study aims To compare the safety and efficacy of ketamine-propofol versus dexmedetomidine-propofol sedation in pediatric patients undergoing cardiac catheterization for device closure of simple left-to-right shunts
- Trial name
- NCT07669012
- Testing
- Ketamine + propofol, Dexmedetomidine + propofol
- Where
- Egypt
- Volunteers
- 124 people
- Sponsor
- Ain Shams University
Pulmonary Vascular Disease
Non-Invasive Diagnosis of Pulmonary Vascular Disease Using Inhaled 129Xe Magnetic Resonance Imaging
This study seeks to deploy several forms of 129Xe MRI contrast as well as emerging conventional proton MRI technqiues for imaging lung structure and perfusion.
- Trial name
- XenonMRI (NCT03078192)
- Testing
- GE-141, Hyperpolarized 129Xenon gas, MRI
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Bastiaan Driehuys
Heart Failure
Comparison of CorWatch With Right Heart Catheter Measurements in Heart Failure
This is an observational study to evaluate the agreement between the InCardia diagnostic technology CorWatch for the assessment of venous pressure in human subjects.
- Trial name
- NCT04928326
- Testing
- CorWatch
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- InCardia Inc.
Heart Failure
A Multi-site, Prospective, Non-interventional, Observational Data Collection Study in Patients Undergoing a Right Heart Catheterization
Acorai is developing a non-invasive monitoring system for the estimation of intracardiac hemodynamic parameters in patients with suspected or confirmed heart failure, and/or pulmonary hypertension, who require hemodynamic…
- Trial name
- NCT07010562
- Testing
- Data collection
- Where
- Sweden
- Volunteers
- 392 people
- Sponsor
- Acorai AB