Clinical trials: Right Ventricular (RV) Dysfunction
Pulmonary Thromboembolisms, Pulmonary Embolism
Low Dose Rt-PA for Acute Normotensive Pulmonary Embolism With RVD
In selected patients with acute pulmonary embolism(PE), low dose (50mg/2h) recombinant tissue plasminogen activator (rt-PA) regimen had been reported to have less bleeding tendency than the FDA-approved rt-PA 100mg/2h regimen…
- Trial name
- NCT01531829
- Testing
- Recombinant tissue plasminogen activator (rt-PA), Low Molecular Weight Heparin
- Where
- 35 sites in China
- Volunteers
- 460 people
- Sponsor
- Beijing Chao Yang Hospital
COPD, Pulmonary Hypertension
Right Ventricular Response to Exercise Among Patients With Chronic Obstructive Pulmonary Disease
This study plans to learn more about heart function among individuals with chronic obstructive pulmonary disease (COPD). In particular, the investigators want to understand the different patterns of right ventricular response…
- Conditions
- COPD, Pulmonary Hypertension, Exercise, Right Ventricular (RV) Dysfunction
- Trial name
- ReV UP COPD (NCT07576894)
- Testing
- Exercise training
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Sick Sinus Syndrome
Right Ventricle (RV) Markers of Future Pacing Induced Ventricular Dysfunction - Pilot
This is a pilot study into the effects on heart function when pacing the right ventricle (RV). This study aims to enrol a population who are clinically indicated to receive a pacemaker.
- Trial name
- NCT02198781
- Where
- United Kingdom
- Volunteers
- 3 people
- Sponsor
- Mid and South Essex NHS Foundation Trust
RV Dysfunction
Paceport Swan-Ganz Data Collection Study
In association with Edwards LifeSciences, the study will aim to develop an algorithm based on right heart (right atrial, right ventricular and pulmonary artery) waveforms for the early detection of RV dysfunction in…
- Trial name
- NCT06812975
- Testing
- No intervention
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- University of Minnesota
RV - Right Ventricular Abnormality, LV Dysfunction
Pediatric Ventricle Function Assessment Study
This study aims to develop a deep learning-based framework for right ventricular (RV) segmentation, prediction of RV fractional area change (FAC), and identification of pediatric RV dysfunction.
- Conditions
- RV - Right Ventricular Abnormality, LV Dysfunction, Pulmonary Hypertension, TOF
- Trial name
- NCT06739057
- Where
- United States
- Volunteers
- 3,993 people, healthy volunteers welcome
- Sponsor
- HBI Solutions Inc.
Acute Exacerbation of COPD, Acute Exacerbation of Bronchiectasis
Outcomes of RV Dysfunction in Acute Exacerbation of Chronic Respiratory Diseases
Observational study in patients with chronic respiratory diseases (chronic obstructive pulmonary diseases, bronchiectasis, interstitial lung diseases, neuromuscular diseases, obesity-hypoventilation syndrome...) admitted in…
- Conditions
- Acute Exacerbation of COPD, Acute Exacerbation of Bronchiectasis, Acute Exacerbation of Asthma, Interstitial Lung Disease
- Trial name
- DVD (NCT04098094)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
RV Dysfunction, Pulmonary Valvuloplasty
Predictors of RV Dysfunction After BPV
This aim focuses on : Assessing how common RV dysfunction is post-procedure Evaluating RV function changes over time (e.g., TAPSE, FAC, RV strain if available) Identifying risk factors or predictors (e.g., high residual gradient…
- Trial name
- NCT07191093
- Testing
- pulmonary valvuloplasty
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Right Coronary Artery Percutaneous Coronary Intervention, Right Ventricular Diastolic Dysfunction
Diastolic RV EvAluation With Millar Catheter to Investigate the Effect of Glucagon-Like Peptide-1 (GLP-1) on Right Ventricular Function During Elective Coronary Angioplasty and Stenting
The heart requires nutrients and oxygen carried in the blood to generate energy for healthy pump function. Blood is supplied via heart vessels called coronary arteries.
- Trial name
- DREAM GLP-1 (NCT02236299)
- Testing
- Right Coronary Artery Percutaneous Coronary Intervention, GLP-1 Infusion
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Heart Failure, Right Ventricular Dysfunction
Mitigating Post-Op RV Dysfunction After LVAD Implantation
This project evaluates right ventricle (RV) protective strategies after left ventricular assist device (LVAD) implantation.
- Conditions
- Heart Failure, Right Ventricular Dysfunction, Right Ventricular Failure
- Trial name
- NCT05758194
- Testing
- Standardized RV Management, Usual Care RV Management
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Chicago
Right Ventricular (RV) Dysfunction
Impella RP Flex with Smart Assist
To capture observational data of the Abiomed Impella RP Flex in a real-world setting.
- Trial name
- NCT06637644
- Testing
- Right-sided ventricular assist device
- Where
- 31 sites in United States
- Volunteers
- 200 people
- Sponsor
- Abiomed Inc.
Respiratory Acidosis in ICU Patients, Right Ventricular (RV) Dysfunction
Right Ventricular Function and Respiratory Acidosis After Cardiac Surgery
Right heart dysfunction remains a frequent cause of morbidity and mortality after cardiac surgery. Respiratory acidosis, particularly when accompanied by hypoxemia, plays a significant role in right heart failure, primarily by…
- Conditions
- Respiratory Acidosis in ICU Patients, Right Ventricular (RV) Dysfunction, Hemodynamic Changes, Mechanical Ventilation
- Trial name
- NCT07619274
- Testing
- Not applicable- observational study
- Where
- Canada
- Volunteers
- 220 people
- Sponsor
- Laval University
CTEPH
Biological Sex and CTEPH-related RV Dysfunction and Recovery (BIOSPHeRe)
1. To identify biological sex differences in baseline RV function in CTEPH 2. To identify biological sex differences in recovery of RV function after PTE surgery in CTEPH 3.
- Trial name
- NCT06105242
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Intermountain Health Care, Inc.
Aortic Valve Disorder
2D Strain of Right Ventricle in Peroperative of Cardiac Surgery
Evaluation of the right ventricle (RV) deformation (strain) with 2D speckle tracking technics obtained by echocardiographies (TEE) in peroperative period of cardiac surgery .
- Trial name
- NCT03298932
- Testing
- Aortic valve surgery
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Right Ventricular Dysfunction
TEE 3D RV Assessment for SAVR, Mini AVR, and TAVR
Three-dimensional echocardiography has become a gold standard to assess right ventricular (RV) function, and investigators plan to use 3D transesophageal echocardiography to assess RV function in 3 types of aortic valve…
- Trial name
- NCT05804240
- Testing
- 3D TEE RVEF
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Thomas Jefferson University
Myeloproliferative Neoplasm, Right Ventricular Dysfunction
Pulmonary Hypertension and RV Dysfunction in Myeloproliferative Neoplasms
This cross-sectional study aims to determine the prevalence of pulmonary hypertension and right ventricular dysfunction in patients with myeloproliferative neoplasms and to identify associated clinical and hematologic factors.
- Conditions
- Myeloproliferative Neoplasm, Right Ventricular Dysfunction, Pulmonary Hypertension
- Trial name
- NCT07834918
- Volunteers
- 145 people
- Sponsor
- Assiut University
Right Ventricular (RV) Dysfunction
Temporary Biventricular Pacing
The hypothesis of this study is that temporary biventricular pacing will improve hemodynamic performance in patients with right ventricular dysfunction after open cardiac chamber cardiac surgery.
- Trial name
- BIPACE (NCT01987531)
- Testing
- left ventricular epicardial pacing lead
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Pennsylvania
Acute Kidney Failure, Mechanical Ventilation Strategies
Driving Pressure Optimization, RV-PA Coupling, and AKI in Mechanically Ventilated Critically Ill Patients
This study evaluates the effect of driving pressure optimization on right ventricular-pulmonary artery (RV-PA) coupling, assessed by TAPSE/PASP ratio, and its association with acute kidney injury (AKI) progression in mechanically…
- Conditions
- Acute Kidney Failure, Mechanical Ventilation Strategies, Right Ventricular (RV) Dysfunction, Critical Illness
- Trial name
- NCT07836387
- Testing
- Driving Pressure-Guided Ventilator Optimization
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Nardin Aymn Boshra
Lung Transplant, Right Ventricular Failure
Right Ventricle Dysfunction in Patients Undergoing Lung Transplant
Patients enlisted for bilateral lung transplantation (LUTX) have subclinical right ventricle (RV) dysfunction1, which is usually clinically silent until LUTX.
- Trial name
- LUTX_strain (NCT05855148)
- Testing
- Enlistment For Lung Transplant
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Policlinico Hospital