Clinical trials: Right Ventricular Dysfunction
Pulmonary Arterial Hypertension, Acute Respiratory Failure
Efficacy and Safety of High-Flow Nasal Cannula Versus Noninvasive Ventilation for Pulmonary Arterial Hypertension-Associated Acute Respiratory Failure
This is a single center, retrospective, propensity score matching cohort study that explores the efficacy and safety of high flow nasal cannula and non-invasive ventilation in the treatment of acute respiratory failure associated…
- Conditions
- Pulmonary Arterial Hypertension, Acute Respiratory Failure, High-flow Nasal Cannula, Noninvasive Ventilation
- Trial name
- HFCNV-PAH (NCT06582459)
- Testing
- HFNC treatment, NIV treatment
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The First People's Hospital of Neijiang
Negative Pressure Ventilation, Right Ventricular Dysfunction
Effects of Negative Pressure Ventilation on Right Ventricular Function in Cardiological Patients
Patients receives induction of general anesthesia for interventional tricuspidal clipping and standard monitoring for this procedure including arterial and central venous line and transesophageal ultrasound.
- Conditions
- Negative Pressure Ventilation, Right Ventricular Dysfunction, Right Ventricular Failure
- Trial name
- NCT06572072
- Testing
- Negative Pressure Ventilation
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Karlsburg Hospital
ARDS Due to Disease Caused by SARS Co-V-2, Right Ventricular Dysfunction
Cardiopulmonary Effects of Prone Position in CARDS
In coronavirus disease-2019 (COVID-19)-related ARDS (C-ARDS), especially in the severe form, increased shunt rate, impaired ventilation/perfusion ratio (V/Q), hypoxic pulmonary vasoconstriction inhibition, and increased immune…
- Trial name
- NCT06456606
- Testing
- before prone position, the first hour of prone position, the first hour of returning to the supine position
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Inferior Wall; Transmural Myocardial Infarction, Right Ventricular Dysfunction
Acute Right Ventricular Infarction Registry
This Study aims to provide an assessment of clinical presentation, management, hospital course, and prognosis of acute right ventricular infarction presenting with or without Inferior or infero-posterior wall Myocardial…
- Trial name
- NCT06424028
- Testing
- Right Ventricular Infarct
- Where
- Pakistan
- Volunteers
- 1,000 people
- Sponsor
- National Institute of Cardiovascular Diseases, Pakistan
Right Ventricular Dysfunction, Stroke Volume Index
Relationship Between Strain and Stroke Volume in Cardiac Surgery
Patients undergoing coronary artery bypass grafting up tp 30% will develop postoperative right ventricle dysfunction. Its imperative for the physician to fully understand the severity of this complication in order to perform an…
- Conditions
- Right Ventricular Dysfunction, Stroke Volume Index, Longitudinal Heart Strain
- Trial name
- NCT04694378
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Tufts Medical Center
Extracorporeal Circulation; Complications, Extracorporeal Membrane Oxygenation Complication
Definition and Management of Right Ventricular Injury in Adult Patients Receiving Extracorporeal Membrane Oxygenation
The aim of this study is to identify existing definitions and therapeutic approaches for acute right ventricular injury (RVI) in patients receiving extracorporeal membrane oxygenation (ECMO) for respiratory support.
- Conditions
- Extracorporeal Circulation; Complications, Extracorporeal Membrane Oxygenation Complication, Right Heart Failure, Right Ventricular Dysfunction
- Trial name
- NCT05948332
- Testing
- Delphi Rounds to generate consensus opinions among Experts
- Where
- United Arab Emirates
- Volunteers
- 52 people
- Sponsor
- Prashant Nasa
Right Ventricular Dysfunction, Right Heart Failure
Right Ventricular Pressure Waveform Monitoring in Cardiac Surgery
RV dysfunction has been associated with increased mortality in the ICU and cardiac surgical patients. Thus, early identification of RV dysfunction at less severe stages will allow for earlier intervention and potentially better…
- Conditions
- Right Ventricular Dysfunction, Right Heart Failure, Congestive Heart Failure
- Trial name
- PACEPORT (NCT04092855)
- Where
- Canada
- Volunteers
- 112 people
- Sponsor
- Montreal Heart Institute
Heart; Dysfunction Postoperative, Cardiac Surgery, Right Heart Failure
Femoral Venous Pulsatility and Right Heart Dysfunction in Heart Surgery: An Observational Study
Right heart failure during cardiac surgery is associated with increased perioperative morbidity and mortality. In this context, it is imperative to develop simple diagnostic tools to detect right heart failure.
- Conditions
- Heart; Dysfunction Postoperative, Cardiac Surgery, Right Heart Failure, Right Ventricular Dysfunction
- Trial name
- FemousTechno6 (NCT05038267)
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Montreal Heart Institute
Ventricular Dysfunction, Right, Lung Diseases
Evaluation of the Right Ventricular Systolic Function Using Real-time Three-dimensional Echocardiography in Intensive Care Unit Patients
Right ventricular failure (RVF) is an independent factor of mortality for many pulmonary diseases. Currently, RVF is defined as the incapacity of the RV to maintain the flow without dilating to use the Frank-Starling law (i.e.…
- Conditions
- Ventricular Dysfunction, Right, Lung Diseases, Intensive Care Units
- Trial name
- REA-3D-VD (NCT04222764)
- Testing
- Real-time three-dimensional echocardiography
- Where
- 2 sites in France
- Volunteers
- 341 people
- Sponsor
- University Hospital, Limoges
COVID-19, ARDS, Human
Cardiac Dysfunction in Critically Ill Covid-19 Patients
We conducted an observation sub-study of the prospective randomized controlled trial "High Dose Inhaled Nitric Oxide in Acute Hypoxemic Respiratory Failure", in which we analysed the echocardiographic data collected both at…
- Conditions
- COVID-19, ARDS, Human, Cardiac Failure, Right Ventricular Dysfunction
- Trial name
- NCT06197256
- Where
- Sweden
- Volunteers
- 39 people
- Sponsor
- Region Stockholm
Ventricular Dysfunction, Right
Test-retest Reproducibility of Right Heart Parameters of Chamber Size and Function
The reliability of advanced echocardiographic and cardiac magnetic resonance (CMR) parameters at repeated measurements is not fully clarified.
- Trial name
- TERRA (NCT06193655)
- Volunteers
- 215 people
- Sponsor
- Istituto Auxologico Italiano
Multi Organ Failure, Left Ventricular Dysfunction
Acute Cardiac Dysfunction in Critical Illnes
The overall aim of the study is to establish the clinical importance of cardiac dysfunction, by estimating its incidence and impact on short- and long-term outcomes, in a mixed population of critically ill patients with…
- Conditions
- Multi Organ Failure, Left Ventricular Dysfunction, Right Ventricular Dysfunction, Tako Tsubo Cardiomyopathy
- Trial name
- NCT05860504
- Testing
- Echocardiography, Cardiac magnetic resonance imaging, Coronary CT
- Where
- Sweden
- Volunteers
- 592 people
- Sponsor
- Sahlgrenska University Hospital
Heart Failure With Reduced Ejection Fraction, Left Ventricular Assist Device
Influence of Right Ventricular Function on Changes in Exercise Capacity After LVAD
This is an exploratory project with the purpose to describe the responses of the right ventricle (RV) and gas exchange during exercise in patients scheduled to undergo left ventricular assist device (LVAD) implant.
- Trial name
- NCT05916612
- Sponsor
- Henry Ford Health System
Pulmonary Valve Malfunction, Right Ventricular Outflow Tract (RVOT) Dysfunction
Pulmonic SAPIEN S3™ THV Registry
Multi-center, Observational Registry with Retrospective Enrollment and Prospective Follow-up. The aim of the registry is to document the feasibility and safety of implanting an Edwards SAPIEN S3 transcatheter heart valve in the…
- Trial name
- PulmonicS3 (NCT02777892)
- Testing
- Sapien S3
- Where
- 4 sites in Canada, Germany and 1 more
- Volunteers
- 50 people
- Sponsor
- Institut für Pharmakologie und Präventive Medizin
End Stage Heart Disease, Right Ventricular Dysfunction
Inhaled Milrinone Use in Patients Receiving HeartMate II LVAD: A Pilot Study
Right ventricular (RV) failure occurs in an estimated 5-41% of cases involving left ventricular assist device (LVAD) implantation and has been shown to adversely affect peri-operative morbidity and mortality.
- Trial name
- NCT01571037
- Testing
- Inhaled, nebulized, Milrinone, inhaled nebulized milrinone
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Nebraska
Chronic Heart Failure, Right Ventricular Dysfunction
Right Ventricular Dysfunction in Chronic Heart Failure
The goal of this multi center observational prospective study is to analyze the concordance between the signs and symptoms of RHF and echocardiographic features of RVD in patient with heart failure.
- Conditions
- Chronic Heart Failure, Right Ventricular Dysfunction, Right Heart Failure
- Trial name
- RIVED-CHF (NCT06002321)
- Testing
- Echocardiography, Laboratory Test
- Where
- 14 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- University of Siena
Right Ventricular Dysfunction
Right Ventricle Dysfunction in Critically Ill Patients
To assess prevalence of right ventricle dysfunction in critically ill patient. To assess impact of RV dysfunction on short term (ICU stay, hospital stay, or mortality ≤30 days) and long term outcome (>30 days).
- Trial name
- NCT05975086
- Volunteers
- 200 people
- Sponsor
- Assiut University
Bronchopulmonary Dysplasia, Right Ventricular Dysfunction
Right vEntricular Function Prediction mOdel to Identify pReterm infanTs With Early BronchoPulmonary Dysplasia.
Short title REPORT-BPD feasibility study Design A mixed methods observational cohort feasibility study Study Setting Neonatal Intensive Care Unit at University Hospitals Plymouth NHS Trust Aim To explore the feasibility of…
- Conditions
- Bronchopulmonary Dysplasia, Right Ventricular Dysfunction, In the Perinatal Period
- Trial name
- REPORT-BPD (NCT05235399)
- Testing
- Echo scans
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University Hospital Plymouth NHS Trust
Ventricular Dysfunction, Right, Hypoxia
Impact of Hypoxia on Resting and Exertional Right Ventricular Performance
The purpose of this study is to better understand how hypoxia (low oxygen) affects resting and exertional right ventricular function in healthy individuals.
- Trial name
- NCT05272514
- Testing
- Hypoxia
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Right Ventricular Dysfunction
Incidence, Impact and Mechanisms of Perioperative Right VEntricular Dysfunction (IMPRoVE)
A study to see how common right heart failure (right ventricular dysfunction) after major surgery is, and to investigate if right ventricular dysfunction causes worse patient outcomes after surgery.
- Trial name
- IMPRoVE (NCT05827315)
- Testing
- Echocardiography, T1 Cardiovascular Magnetic Resonance, Right heart catheterisation and coronary sinus blood sampling
- Where
- 3 sites in United Kingdom
- Volunteers
- 175 people
- Sponsor
- NHS National Waiting Times Centre Board