Clinical trials: Right Ventricular Function
Heart Block, Heart Block Complete
Effect of Site of Right Ventricular (RV) Pacing on RV Function, Left Ventricular (LV) Dyssynchrony and Contraction Efficiency
To evaluate RV systolic function and LV mechanical dyssynchrony and function in different lead position in the RV during permanent pacemaker implantation by using speckle tracking echocardiography (STE) and 3D volumetric ejection…
- Conditions
- Heart Block, Heart Block Complete, Systolic Function
- Trial name
- NCT06636851
- Testing
- Pacemaker and defibrillator
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- South Valley University
Effect of Pericardial Closure on the Right Ventricular Function Post Cardiac Surgery, Open Heart Surgery
Does the Pericardial Closure Reduces Early Right Ventricular Dysfunction After Cardiac Surgery: A Randomized Controlled Trial
The right ventricular (RV) function has a major influence on the outcomes of cardiac surgery[1,2]. Also affects the prognosis of patients undergoing heart surgery, where the development of right ventricular failure after surgery…
- Trial name
- NCT07836426
- Testing
- close pericardium
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Primary Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension
Effects of Riociguat on RIght VEntricular Size and Function in PAH and CTEPH
This is an open-label, single-armed, prospective single-centre clinical study to evaluate the effect of riociguat on right heart size and function in patients with manifest PAH and CTEPH.
- Trial name
- RIVERII (NCT04954742)
- Testing
- Riociguat
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Heidelberg University
Ventricular Dysfunction, Right, Lung Diseases
Evaluation of the Right Ventricular Systolic Function Using Real-time Three-dimensional Echocardiography in Intensive Care Unit Patients
Right ventricular failure (RVF) is an independent factor of mortality for many pulmonary diseases. Currently, RVF is defined as the incapacity of the RV to maintain the flow without dilating to use the Frank-Starling law (i.e.…
- Conditions
- Ventricular Dysfunction, Right, Lung Diseases, Intensive Care Units
- Trial name
- REA-3D-VD (NCT04222764)
- Testing
- Real-time three-dimensional echocardiography
- Where
- 2 sites in France
- Volunteers
- 341 people
- Sponsor
- University Hospital, Limoges
Tricuspid Regurgitation
Tricuspid Cardiopulmonary Exercise Study
Tricuspid regurgitation (TR), which in close to 90% of cases is functional as a consequence of left-sided heart failure, left heart valve abnormalities or pulmonary (vascular) disease, is associated with adverse patient outcomes…
- Trial name
- TRCPET (NCT04559256)
- Testing
- Cardiopulmonary Exercise Testing
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Heart and Diabetes Center North-Rhine Westfalia
Right Ventricular Function
RV Function Evaluation Assessed by Strain and Validated by MRI
Echocardiographic assessment of right ventricular function is an important diagnostic tool, and is a challenge due to the unique structure and anatomy of the right ventricle.
- Trial name
- NCT02326701
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Hadassah Medical Organization
Right Ventricular Dysfunction
Right Ventricular Echocardiography in caRdiac SurgEry
Postoperative right ventricular (RV) dysfunction increases mortality and risk of cardiac failure after cardiac surgery substantially.
- Trial name
- ReVERSE (NCT03301571)
- Testing
- Change in preload and afterload, Inspired oxygen, Pacemaker mode
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Altitude Hypoxia, Hypoxia
Effect of Acute Hypoxia on RIght VEntRicular Function in HAPE.
More and more people are engaging in sports in the mountains, including individuals with heart or lung diseases. At the same time, such diseases are becoming more common in Switzerland.
- Conditions
- Altitude Hypoxia, Hypoxia, Normobaric Hypoxia, Right Ventricular Function
- Trial name
- RIVER-HAPE (NCT07431554)
- Testing
- Normobaric Hypoxia
- Where
- Switzerland
- Volunteers
- 18 people
- Sponsor
- Mona Lichtblau
Bronchopulmonary Dysplasia, Right Ventricular Dysfunction
Right vEntricular Function Prediction mOdel to Identify pReterm infanTs With Early BronchoPulmonary Dysplasia.
Short title REPORT-BPD feasibility study Design A mixed methods observational cohort feasibility study Study Setting Neonatal Intensive Care Unit at University Hospitals Plymouth NHS Trust Aim To explore the feasibility of…
- Conditions
- Bronchopulmonary Dysplasia, Right Ventricular Dysfunction, In the Perinatal Period
- Trial name
- REPORT-BPD (NCT05235399)
- Testing
- Echo scans
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University Hospital Plymouth NHS Trust
ARDS Due to Disease Caused by SARS Co-V-2, Right Ventricular Dysfunction
Cardiopulmonary Effects of Prone Position in CARDS
In coronavirus disease-2019 (COVID-19)-related ARDS (C-ARDS), especially in the severe form, increased shunt rate, impaired ventilation/perfusion ratio (V/Q), hypoxic pulmonary vasoconstriction inhibition, and increased immune…
- Trial name
- NCT06456606
- Testing
- before prone position, the first hour of prone position, the first hour of returning to the supine position
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Right Ventricular Dysfunction, Rheumatic Heart Disease
Right Ventricular Echo Assessment in Mitral Valve Replacement
Rheumatic heart disease remains a major health problem in developing countries. It is the most important sequel of rheumatic fever and occurs in about 30% of patients with rheumatic fever.Rheumatic heart disease presents with…
- Trial name
- NCT03549052
- Volunteers
- 120 people
- Sponsor
- Assiut University
Pulmonary Hypertension, Valvular Heart Disease
Evaluating Right Ventricular (RV) Size and Function Using the Upper Valley RV Algorithm and Novel Imaging Modalities
The primary purpose of this study is to evaluate the diagnostic performance of three methods for measuring right ventricular size and function including the Philips Novel RV quantification technologies (RV Heart Model volumetric…
- Conditions
- Pulmonary Hypertension, Valvular Heart Disease, Congenital Heart Disease, Congestive Heart Failure
- Trial name
- UVRV (NCT03935178)
- Testing
- Measuring Right Ventricular Size and Function
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Right Ventricular Dysfunction
New Echocardiographic Methods for Right Ventricular Function.
Aims of this study are the evaluation of new echocardiographic methods (3D/4D- and strain-echocardiography) for measurement of the right ventricular (RV) function .
- Trial name
- NEW-RV (NCT01230294)
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Right Ventricular Dysfunction
Right Ventricular Function Changes After CIED Implantation: The RIGHT-CIED Study
This study aims to understand how the right side of the heart changes in people who receive an implantable cardiac electronic device (CIED), such as a pacemaker, ICD, or CRT device.
- Trial name
- RIGHT-CIED (NCT07272395)
- Testing
- Multimodal Right Ventricular Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University - Cerrahpasa
Pulmonary Edema Cardiac Cause
HF vs NIV in Acute Cardiogenic Pulmonary Edema
The study's primary aim is to compare the effects of two different ventilation modalities, non-invasive positive-pressure ventilation (NPPV) and high-flow nasal cannulae (HFNC), in the acute cardiogenic pulmonary edema (ACPE)…
- Trial name
- HFvsNIV (NCT05989139)
- Testing
- NPPV/HFNC, HFNC/NPPV
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Dilated Cardiomyopathy, Heart Failure
Assessment of Right Ventricular Function in Advanced Heart Failure
We examined the feasibility and reliability of a combined echocardiographic and right heart catheterization (RHC) approach for right ventriculo/arterial (R-V/A) coupling assessment in HF patients with dilated cardiomyopathy…
- Trial name
- NCT03893760
- Testing
- Ventriculo-arterial coupling assessment (R-V/A)
- Where
- 2 sites in Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ITAB - Institute for Advanced Biomedical Technologies
Pacemaker-Induced Cardiomyopathy, Tricuspid Regurgitation
Comparing the Effects of Newer Pacemakers and Their Effects on the Heart and Valve Function in the Short-term.
Conventional pacemakers involve placing a lead through a valve into the bottom right chamber of the heart. Research has shown that this approach is associated with an increased risk of valve dysfunction, mortality, and impairment…
- Conditions
- Pacemaker-Induced Cardiomyopathy, Tricuspid Regurgitation, Right Ventricular Dysfunction
- Trial name
- LvL-PACE (NCT07534917)
- Testing
- Temporary left bundle branch area pacing, Temporary leadless right ventricular pacing
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Pulmonary Hypertension
11C-acetate/18Fluorodeoxyglucose-FDG PET/CT and Cardiac MRI in Pulmonary Hypertension
This study is looking at differences in metabolism and functional imaging between pulmonary hypertension subjects with normal right ventricular function and persistent right ventricular dysfunction.
- Trial name
- NCT01917136
- Testing
- 11C-acetate, [18F]Fluoro-2-deoxy-2-D-glucose, Cardiac MRI
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Pennsylvania
Pulmonary Hypertension
Correlation of Right Atrial Strain With Pulmonary Hypertension, Right Ventricular Function And Outcome In Pediatric Patients
This observational study aims to assess correlation of right atrial strain measured by two-dimensional speckle tracking echocardiography with intraoperatively measured pulmonary artery pressures, other indices of right…
- Trial name
- NCT05699681
- Testing
- Transthoracic and transesophageal echocardiography
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Heart Valve Incompetence, Atrial Fibrillation, Persistent
In-depth Characterization of Atriogenic Secondary Tricuspid Regurgitation Due to Atrial Fibrillation
1050 patients with persistent/permanent atrial fibrillation (AF) will be studied using conventional and advanced (three-dimensional and deformation imaging) echocardiography.
- Trial name
- ASTRA (NCT05749107)
- Testing
- Echocardiography, Proteomic analyses
- Where
- 2 sites in Italy
- Volunteers
- 1,050 people
- Sponsor
- Istituto Auxologico Italiano