Clinical trials: Ringer's Lactate
Fluid Therapy
Crystalloid FLUID Choices for Resuscitation of Hospital Patients
Salt fluids are used extensively for acutely ill patients who are admitted to hospital. Two salt fluids commonly used are Normal Saline and Ringer's Lactate.
- Trial name
- FLUID (NCT02721485)
- Testing
- Ringer's Lactate, Normal Saline
- Where
- 4 sites in Canada
- Volunteers
- 30,000 people
- Sponsor
- Ottawa Hospital Research Institute
Hemodynamic Stability
Lactated Ringer's Versus 5% Human Albumin: Cardiac Surgical Patients
The purpose of this study is to show which of two different types of fluid is best for cardiac surgical patients. During and after the subject's heart surgery, the subject will be given either Lactated Ringer's or 5% human…
- Trial name
- NCT02654782
- Testing
- Lactated Ringer's, 5% Human Albumin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- William C. Oliver
Acid-Base Balance Disorder
Comparison of Plasmalyte A, Normal Saline and Ringer Lactate as Intraoperative Fluid During Renal Transplantation
Fluid management being an important component of surgery becomes more challenging for an anesthesiologist in case of renal transplant.
- Trial name
- NCT03115060
- Testing
- intravenous fluid administration WITH NORMAL SALINE, PLASMALYTE A, OR RINGER LACTATE
- Where
- India
- Volunteers
- 105 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Trauma
Trial Of Normal Saline Versus Ringer's Lactate In Paediatric Trauma Patients
Background: Trauma is a major cause of death in children and teenagers. When young patients have suffered major traumatic injuries, they require intravenous (iv) fluids to keep their blood vessels full and ensure blood flow to…
- Trial name
- NCT01692769
- Testing
- Normal Saline, Ringer's Lactate
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Pancreatitis
High Volume Lactated Ringer's Solution and Pancreatitis
The purpose of this study is to examine whether giving large amounts of intravenous (IV) fluids will reduce the risk of developing a complication known as post-ERCP pancreatitis (PEP).
- Trial name
- NCT02050048
- Testing
- Administration of Lactated Ringer's (LR) Solution
- Where
- 6 sites in United States
- Volunteers
- 26 people
- Sponsor
- Endeavor Health
Coagulopathy
Comparison Between Colloids and Crystalloids on Coagulation and Blood Loss
Infusion of intravenous fluids is mandatory especially in major and prolonged surgeries. However, there is no available optimum ideal type of fluid nor a fixed amount suitable for transfusion but it must be individualized for…
- Trial name
- NCT06683079
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Peritonitis, Intoxication
Efficacy and Safety of Rheosorbilact® Solution for Infusion, in a Complex Therapy of Peritonitis
This study evaluates the efficacy and safety of Rheosorbilact®, solution for infusion ("Yuria-Pharm" LLC), in comparison with Ringer's Lactate, solution for infusion, in a complex therapy of peritonitis.
- Trial name
- NCT03771170
- Testing
- Rheosorbilact®, Ringer lactate
- Where
- 10 sites in Georgia, Moldova and 2 more
- Volunteers
- 180 people
- Sponsor
- Yuria-Pharm
Acute Kidney Injury
Isotonic Solution Administration Logistical Testing
The administration of intravenous crystalloids is ubiquitous in the care of the critically ill. Commonly available crystalloid solutions contain a broad spectrum of electrolyte compositions including a range of chloride…
- Trial name
- SALT (NCT02345486)
- Testing
- 0.9% sodium chloride, Physiologically balanced fluid
- Where
- United States
- Volunteers
- 974 people
- Sponsor
- Vanderbilt University
Right Ventricular Impaired Function, Hypovolemia
Comparison of the Effects of an Hypertonic Solution With Ringer Lactate on Right Ventricular Function Following Cardiac Surgery
This study is a phase III, randomized, controled, parallel groups, single blinded, clinical trial that aims at comparing the improvement of right ventricular function after administration of a hypertonic solution versus Ringer…
- Trial name
- SUCCESS (NCT02782520)
- Testing
- Ringer Lactate (10ml/kg) fluid expansion, Hypertonic saline (3ml/kg) fluid expansion
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Grenoble
Postoperative Complications
Saline Versus Lactated Ringer's Solution: The SOLAR Fluid Trial
Perioperative volumes of saline cause a mild acidosis compared with buffered fluids. On the other hand, saline administration maintains plasma osmolality and better repletes vascular volume which is an important goal of…
- Trial name
- NCT02565420
- Testing
- Normal saline, Lactated Ringer's solution
- Where
- United States
- Volunteers
- 8,616 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Induced Labor
Lactated Ringer's and Dextrose 5% vs Only Lactated Ringer's in Labor
The goal of this clinical trial is to determine which of two types of standard intravenous (IV) fluids (a combination of 5% dextrose and Lactated Ringers solution and Lactated Ringers solution alone) has a better influence on…
- Trial name
- NCT07124130
- Testing
- 5% Dextrose (D5) in Normal Saline (NS), Lactate Ringer
- Where
- 2 sites in United States, Italy
- Volunteers
- 158 people
- Sponsor
- Eastern Virginia Medical School
Post-ERCP Pancreatitis, Pancreatitis
Short-Stay Aggressive Hydration to Prevent Post-ERCP Pancreatitis
Post-ERCP pancreatitis (PEP) is the most common serious adverse event after endoscopic retrograde cholangiopancreatography (ERCP), occurring in roughly 7-15% of patients.
- Trial name
- PuSH (NCT07776561)
- Testing
- Short-Stay Aggressive Hydration, Standard Peri-procedural Hydration, Rectal Indomethacin
- Where
- Australia
- Volunteers
- 1,300 people
- Sponsor
- Westmead Hospital
Diabetes Mellitus, Type 2
Hartmann's Solution and Normal Saline in Type II Diabetes Patients
The purpose of this study is to determine whether perioperative use of Hartmann's solution in type II diabetes patients increases blood glucose level after surgery.
- Trial name
- NCT02305199
- Testing
- Hartmann's solution, Normal saline
- Where
- South Korea
- Sponsor
- Yeungnam University College of Medicine
Normal Anion Gap Metabolic Acidosis
Ringer's Lactate Versus Normal Saline in Caesarean Section
The objective of this study is to compare the effect on mean maternal and neonatal pH, and 24-hour postoperative morbidity, following intraoperative infusion of Ringer's Lactated versus normal saline in caesarean section at…
- Trial name
- NCT01585740
- Testing
- 0.9% Normal Saline, Ringer's Lactate
- Where
- Uganda
- Volunteers
- 500 people
- Sponsor
- Makerere University
Coronary Artery Bypass Graft Surgery, Aortic Valve Replacement
Outcomes After Albumin Vs Lactated Ringer's Solution in CABG and AVR Procedures
This is a prospective, randomized, double-blinded study to compare the use of albumin versus lactated Ringer's solution in patients undergoing coronary artery bypass graft surgery and in patients undergoing aortic valve…
- Trial name
- NCT04652375
- Testing
- Albumin Solution, Lactated Ringer's Solution
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- Yale University
Dengue Shock Syndrome
Effect of Hypertonic Sodium Lactate on sVCAM-1 Level as Surrogate Marker of Endothelial Capillary Leakage in Pediatric Dengue Shock Syndrome Patients (DSS)
Dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) are among the leading causes of pediatric hospitalization in Asia.Mortality rates range from 1% at centres experienced in fluid resuscitation, to upto 44% in…
- Trial name
- NCT00966628
- Testing
- Hypertonic sodium lactate, Ringer's lactate
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Innogene Kalbiotech Pte. Ltd
Electrolyte Imbalance, Kidney Transplant; Complications
The Comparison Between Ringer Lactate Solution and Normal Saline With Dextrose Water in Post-Operative Period of Kidney Transplantation
This is a randomized controlled pragmatic clinical trial. We aim to evaluate the effect of Ringer lactate solution (RLS) and normal saline solution (NSS) with dextrose water (D5W) on the electrolyte abnormality of kidney…
- Trial name
- RINNOR (NCT06030609)
- Testing
- Ringer's Lactate Crystalloid Solutions, Normal saline
- Where
- Thailand
- Volunteers
- 159 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Anesthesia, Ringer's Lactate
Ringer Lactate Preloading on Induction Dose Requirement of Propofol
To compare the effect (heart rate and mean arterial pressure) of Ringer Lactate preloading and without preloading on induction dose requirement of Propofol.
- Trial name
- NCT05777135
- Testing
- Ringer Lactate prior to surgery and Propofol
- Where
- Nepal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Medical College Birgunj
Postoperative Inflammation
A Comparative Study of Volume Replacement With HES 130/0.4 Versus Ringer's Lactate (RL) Regarding Their Effects on Inflammatory Biomarkers (Cytokines and Matrix Metalloproteinases) Responses to Major Abdominal Surgery.
Various stimuli such as trauma, infection and major surgery may alter the physiologic immune balance and initiate systemic inflammatory processes.
- Trial name
- NCT01880190
- Testing
- Ringer's Lactate, HES 130/0.4 and Ringer's Lactate
- Where
- Greece
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Paraskevi Matsota
Efficacy, Safety
Effect of PPV+ILM Peeling +/- Subretinal Injection of Ringer Lactate in Management of Nontractional Refractory DME
To evaluate the efficacy and safety of combined pars plana vitrectomy and planned foveal detachment through subretinal injection of ringer's solution in patients with non-tractional refractory diabetic macular edema.
- Trial name
- NCT06271473
- Testing
- vitrectomy + ILM peeling +/- planned foveal detachment via subretinal injection of ringer's solution.
- Where
- 2 sites in Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University