Clinical trials: Ringer's Lactate
Sepsis
Normal Saline Versus Ringer's Lactate for Initial Fluid Resuscitation in Sepsis
This clinical trial aims to determine if the type of intravenous fluid used for initial resuscitation affects the short-term outcomes of adult patients with sepsis who are treated in the emergency department.
- Trial name
- NCT07240701
- Testing
- Ringer's Lactate, Normal Saline (0.9% Sodium Chloride)
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Egemen Yildiz
Post-ERCP Acute Pancreatitis
Lactated Ringers With or Without Rectal Indomethacin to Prevent Post-ERCP Pancreatitis
Post-ERCP pancreatitis is a well-known and sometimes life-threatening complication of ERCP. Both LR and rectal indomethacin have shown benefit in preventing post-ERCP pancreatitis.
- Trial name
- IND+LRPEP (NCT02641561)
- Testing
- Indomethacin, Lactated Ringer's Solution, Normal Saline
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- The Cooper Health System
Cataract
Study of Corneas Undergoing Balanced Salt Solution(BSS ®) Versus Glucose-bicarbonate-Ringer Lactate in Cataract Surgery
This is a study aimed at evaluating the effectiveness and impact of two intraocular irrigating solution (BSS ® versus glucose-bicarbonate-Ringer Lactate - GBRL) on the health of the cornea after cataract surgery by…
- Trial name
- NCT01334658
- Testing
- Phacoemulsification cataract surgery, Glucose-bicarbonate-Ringer Lactate (GBRL), Balanced Salt Solution (BSS®)
- Volunteers
- 64 people
- Sponsor
- Grupo de Estudos em Oftalmologia Clínica e Cirúrgica
Peritoneal Neoplasms, Hyperthermic Intraperitoneal Chemotherapy
Efficacy of Intraoperative Use of 20% Albumin Combined With Ringer Lactate Versus Ringer Lactate During Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy
Introduction Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is considered as the standard of care for the treatment of peritoneal metastases.
- Conditions
- Peritoneal Neoplasms, Hyperthermic Intraperitoneal Chemotherapy, Intraoperative Care, Fluid Therapy
- Trial name
- ALBUCHIP (NCT06351475)
- Testing
- Intra-operative albumin administration, Control
- Where
- 8 sites in France
- Volunteers
- 140 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fluid and Electrolyte Imbalance
Volume Kinetics of Fluid Resuscitation in Early Sepsis
The recommended volume resuscitation for patients with early sepsis-induced hypoperfusion is at least 30 ml/kg of crystalloid administered within the first three hours.
- Trial name
- NCT06499701
- Testing
- Ringer's Lactate
- Where
- 2 sites in Romania
- Volunteers
- 13 people
- Sponsor
- Institutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu
Hyperlactatemia
Does Intravenous Lactated Ringer Solution Raise Measured Serum Lactate?
Lactated Ringer's (LR) solution bolus is commonly administered in the emergency department setting to seriously ill patients. It is also common to obtain blood samples to determine serum lactate levels to aid in the assessment of…
- Trial name
- NCT02950753
- Testing
- Lactated Ringer Solution, Normal Saline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Medical Center of Southern Nevada
Healthy
Study of Subcutaneous Hydration Enabled by Human Recombinant Hyaluronidase (Hylenex)
Randomized, double-blinded study that will evaluate the tolerability, safety, and flow rates of different solutions subcutaneously (SC) infused and preceded by human recombinant hyaluronidase (hylenex) 150 units.
- Trial name
- INFUSE-NSLR (NCT00656370)
- Testing
- recombinant human hyaluronidase
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Halozyme Therapeutics
Septicemic Shock
High Strong Ion Difference Fluid vs Hartmann's Solution on Acid-Base Status in Sepsis
This is a research to study primarily the effect of rapidly infused high strong ion difference (SID) fluid vs Hartmann's solution in altering the pH and bicarbonate level of the patient, who is in sepsis with metabolic acidosis.
- Trial name
- HiSIDSS (NCT03530046)
- Testing
- High SID fluid, Hartmann's solution
- Volunteers
- 162 people
- Sponsor
- Clinical Research Centre, Malaysia
Acute Pancreatitis
Lactated Ringers vs Normal Saline in Patients With Acute Pancreatitis: A Bias-Adjusted Meta-analysis
This study aims to compare NS and LR in terms of outcomes in patients with acute pancreatitis while addressing the current methodological issues with available meta-analyses on the topic.
- Trial name
- NCT05638555
- Where
- Qatar
- Volunteers
- 500 people
- Sponsor
- Qatar University
Pancreatitis, Chronic, Pancreatic Duct Stone
Aggressive Intravenous Hydration With Lactated Ringer's Solution for Prevention of Post-ESWL Pancreatitis
The goal of this clinical trial is to clarify whether aggressive intravenous hydration with lactated Ringer's solution could reduce the incidence of post-ESWL pancreatitis in patients with chronic pancreatitis.
- Trial name
- HYPER (NCT05772234)
- Testing
- Lactated ringers solution, normal saline
- Where
- China
- Volunteers
- 1,066 people
- Sponsor
- Changhai Hospital
Ringer's Lactate
Fluid Management in the Post Anesthesia Care Unit
Fluid therapy is a cornerstone in patient therapy perioperatively. Many studies have addressed the amount of fluid administered (restrictive vs liberal strategies).
- Trial name
- NCT03799250
- Testing
- Ringer lactate, standard care
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Rabin Medical Center
Hemorrhagic Shock
Efficacy, Safety of Solution Containing Hyperosmolar Sodium Lactate Infusion for Resuscitation of Patients With Hemorrhagic Shock
Indication: Resuscitation in pts with hemorrhagic shock due to multiple injuries Prospective, open label RCT in pts. with traumatic hemorrhagic shock in RS Hasan Sadikin Hospital, Indonesia. PI: Dr.
- Trial name
- NCT01433276
- Testing
- Hyperosmolar sodium lactate, Ringer's lactate
- Where
- Indonesia
- Volunteers
- 71 people
- Sponsor
- Innogene Kalbiotech Pte. Ltd
Pancreatitis, Chronic, Pancreatitis, Acute
Indometacin With or Without Aggressive Intravenous Hydration to Prevent Pancreatitis After Pancreatic Extracorporeal Shock Wave Lithotripsy
This study aims to determine whether combining aggressive intravenous hydration with indometacin is more effective at preventing pancreatitis after a Extracorporeal Shock Wave Lithotripsy (ESWL) than using indometacin alone.
- Conditions
- Pancreatitis, Chronic, Pancreatitis, Acute, Pancreatic Duct Stones
- Trial name
- NCT07202559
- Testing
- Indometacin suppository, Lactated ringers solution, Normal Saline
- Where
- 10 sites in China
- Volunteers
- 1,250 people
- Sponsor
- Changhai Hospital
Hip Replacement Arthroplasty
Comparison Between Two Techniques of Volemic Expansion in Hip Replacement Arthroplasty
Currently the most use solution to volemic reposition in hip replacement arthroplasty is the crystalloid solution. This trial intends to compare two different volemic replacements: HES and Ringer's lactate.
- Trial name
- NCT00542516
- Testing
- Hydroxyethyl Starch, Ringer's lactate
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Severe Burn Injury
Balanced Volume Replacement Therapy With Ringer's Acetate Solution in Burn Injury
This observational study compares the influence of Ringer's Lactate solution and Ringer's Acetate solution on organ function scores following severe burn injury.
- Trial name
- VoLTRAB (NCT00609700)
- Where
- Germany
- Volunteers
- 82 people
- Sponsor
- Klinikum St. Georg gGmbH
Cholangiopancreatography, Endoscopic Retrograde, Pancreatitis
Tailored Hydration for the Prevention of Post-ERCP Pancreatitis
Aggressive hydration of lactated Ringer's solution has shown considerable beneficial effect in preventing post-ERCP(endoscopic retrograde cholangiopancreatography) pancreatitis.
- Trial name
- NCT03561441
- Testing
- Tailored aggressive hydration, Tailored standard hydration
- Where
- South Korea
- Volunteers
- 350 people
- Sponsor
- Chonnam National University Hospital
Fluid Loss, Symptom Complex, Triple
Saline vs. Lactated Ringers for Emergency Department IV Fluid Resuscitation
Administration of intravascular (IV) fluid is the most common emergency department (ED) procedure. IV fluids are integral to increasing effective blood volume and ensuring organ perfusion in patients with volume depletion and…
- Conditions
- Fluid Loss, Symptom Complex, Triple, Emergencies
- Trial name
- NCT03133767
- Testing
- Lactated Ringer Solution, Normal Saline 0.9% Infusion Solution Bag
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- Nicholas M Mohr
Myocardial Injury
Comparison of Lactated Ringer's Solution and PlasmaLyte-A as a Base Solution for Del Nido Cardioplegia
Del Nido cardioplegia has been used exclusively for myocardial protection in pediatrics cardiac surgery for decades. Its unique properties including lidocaine which helps counteract potassium depolarization of the myocardial cell…
- Trial name
- NCT04051580
- Testing
- Lactated Ringer
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Mahidol University
Hyponatremia
Comparison of Ringer Lactate and Isotonic Acetate Solution as Perioperative Maintenance Fluid for Children
In children fluids are supplemented during surgery to provide volume, to maintain blood glucose levels, electrolyte balance and to meet the ongoing fluid losses during surgery.
- Trial name
- NCT02936167
- Testing
- Ringer Lactate, Plasmalyte
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Severe Sepsis With Septic Shock, Lactate
Using Sodium Lactate Ringer's Injection Resuscitate Septic Shock Patients
Using sodium lactate Ringer's injection resuscitate septic shock patients and Compared with other solution, in order to make clear whether can improve the prognosis.
- Trial name
- NCT02449928
- Testing
- sodium lactate Ringer's injection(Baxter, ShangHai, China), Compound Sodium Chloride Injection (CR Double-Crane, Beijing, China)
- Sponsor
- Peking Union Medical College Hospital