Clinical trials: Risk Behavior
Substance-Related Disorders, Depression
Wraparound for High-risk Families with Substance Use Disorders: Examining Family, Child, and Parent Outcomes
The investigators propose a Hybrid Type 1 effectiveness-implementation quasi-experimental trial. Participants are drawn from two different communities contemporaneously.
- Conditions
- Substance-Related Disorders, Depression, Stress Disorders, Post-Traumatic, Child Abuse
- Trial name
- NCT04637581
- Testing
- Wraparound
- Where
- 4 sites in United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Alcohol Drinking in College
Alcohol Brief Intervention Plus Personalized Mobile Chat-based Intervention for High-risk Drinking University Students
The aims of this pilot study are: 1. To examine the factors associated with alcohol drinking and alcohol use disorder 2. To examine the effect of face-to-face alcohol brief intervention on drinking reduction 3.
- Trial name
- NCT03675373
- Testing
- Mobile chat-based instant messages, Alcohol brief intervention
- Where
- Hong Kong
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Colorectal Neoplasms, Mass Screening
Preventing Early-Onset Colorectal Cancer in the VA
Colorectal cancer is a leading cause of cancer death among Veterans. The starting age for colorectal cancer screening has been lowered from 50 to 45 years in response to the rising incidence of early-onset colorectal cancer…
- Trial name
- PRECISE (NCT07071454)
- Testing
- Patient intervention, PCP intervention
- Where
- United States
- Volunteers
- 536 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Behavior, Cardiovascular Risk Factor
The Oakland Men's Health Disparities Study
Reducing racial disparities in health outcomes is a major policy concern in the United States. Although there has been recent progress to close the gap, black men continue to experience earlier morbidity and mortality from…
- Conditions
- Behavior, Cardiovascular Risk Factor, Influenza
- Trial name
- NCT03481270
- Testing
- Concordant
- Where
- United States
- Volunteers
- 1,374 people, healthy volunteers welcome
- Sponsor
- Stanford University
Tobacco Use, Drug Use
Preventing Cigarette Use Among Urban Youth Via an M-Health Primary Care Preventive Intervention
The study aims to develop tobacco modules to be included in an innovative mobile-health (mHealth) intervention (hereon referred to as S4E) and to determine the feasibility and preliminary efficacy of the updated version of S4E in…
- Conditions
- Tobacco Use, Drug Use, Adolescent Behavior, Alcohol Use
- Trial name
- NCT03855410
- Testing
- S4E, Attention-Matched Control Group
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Social Medium, Data Collection
Social Media-based Vaccine Confidence and Hesitancy Monitoring
History and scientific evidence show that it is critical to maintain public trust and confidence in vaccination. Any crisis in confidence has the potential to cause significant disruption and a detrimental impact on vaccination.
- Conditions
- Social Medium, Data Collection, Patient Acceptance of Health Care, Immunization Programs
- Trial name
- NCT05442762
- Volunteers
- healthy volunteers welcome
- Sponsor
- Fudan University
Chronic Non-communicable Disease
Risk Factors at Chronic Non-communicable Diseases in People of Working Age
Objectives: to study the clinical and demographic characteristics of working age persons, to highlight the main factors of non-communicable diseases (NCDs), to identify NCDs with physical examination, laboratory tests…
- Trial name
- FORTUNE (NCT06812767)
- Testing
- electrocardiography, analysis for glucose and cholesterol in the capillary blood, detection of microalbumuria
- Where
- Russia
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Smoking, Pregnancy
Effectiveness of Nicotine Replacement Therapy in Reducing the Risk of Nicotine Exposure in Pregnant Minority Smokers
This study will compare the effectiveness of counseling plus use of a nicotine patch with counseling alone for helping pregnant women quit smoking.
- Trial name
- NCT00341432
- Testing
- Nicotine Replacement Therapy
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Young-onset Dementia
YOD-RiSoCo: Social Cognition and Risk-taking Behaviour in Patients with Young-onset Dementia
The goal of this observational study is to learn about social cognition and risky behaviour in patients with young-onset dementia (YOD).
- Trial name
- YOD-RiSoCo (NCT06286293)
- Testing
- Neuropsychological assessment, driving simulator task
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Burn Out
Preventing Burnout Among Caregivers Through Physical Activity
The purpose of this study is to evaluate the impact of an adaptive physical activity programme to prevent the risk of burnout at the end of the programme (10 weeks after the start of the intervention).
- Trial name
- PACA (NCT06815484)
- Testing
- Intervention group with physical activity programme, Recommendations of the World Health Organisation
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
HIV Infections, Hiv
Acceptability, Feasibility, and Preliminary Impact of a Web-based, HIV Prevention Toolkit With Cisgender Male Couples in Lima, Peru
This digital couples-based HIV/STI prevention intervention project will determine preliminary efficacy to improve uptake of evidence-based strategies and a tailored prevention plan among cisgender male couples who are in a…
- Conditions
- HIV Infections, Hiv, Sexually Transmitted Infections (Not HIV or Hepatitis), Sexually Transmitted Diseases
- Trial name
- NCT05873855
- Testing
- Para ti, para mi, para nosotros (P3), Waitlist Control Para ti, para mi, para nosotros (P3)
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Florida International University
Psychiatric Disorders
TORCH - Transdiagnostic Observation of Risk Factors, Craving and Health Behaviours in Psychiatric Patients
Mental disorders are often accompanied by health-risk behaviours, psychiatric comorbidity, and reduced functioning. TORCH investigates transdiagnostic mechanisms underlying multiple health behaviour change in adult psychiatric…
- Trial name
- TORCH (NCT07844798)
- Testing
- person-centred interventions
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jacobs University Bremen gGmbH
Risk Reduction
Point-of-care Urine Monitoring of Adherence: Testing a Real-Time Urine Assay of Tenofovir in PrEP
Worldwide expansion of pre-exposure prophylaxis (PrEP) with oral tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) will be critical to ending the HIV epidemic.
- Trial name
- PUMA (NCT03935464)
- Testing
- PUMA
- Where
- Kenya
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Substance Abuse, HIV
Reducing High Risk Behavior in Treatment Court
This study will be the first to examine the efficacy of using a brief, computerized HIV risk reduction intervention in treatment courts.
- Trial name
- NCT01481428
- Testing
- Computer-facilitated HIV intervention, Attention Control
- Where
- United States
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- Treatment Research Institute
Overweight and Obesity
Intermittent Fasting Compared to Continuous Energy Restriction on Body Weight Loss
Obesity remains a major public health challenge. Intermittent fasting continues to gain popularity compared to continuous energy restriction as a weight-loss approach for cardiometabolic health.
- Trial name
- NCT04526847
- Testing
- Intermittent energy restriction (IER) : 5:2 diet pattern, Continuous energy restricted (CER) group
- Where
- Nepal
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Armed Police Force Hospital, Nepal
Sexual Behavior, Depression
Our Family Our Future: Acceptability and Feasibility Study of a Family Prevention Program for HIV Risk and Depression
The purpose of this study is to assess the feasibility and acceptability of a family-based preventive intervention designed to reduce sexual risk behaviors and depressive symptoms among South African adolescents and their…
- Trial name
- NCT02432352
- Testing
- Our Family Our Future
- Where
- South Africa
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Brown University
Endothelial Function, Aerobic Exercise
VascuFit: Exercise and Vascular Aging
Exercise is a cornerstone of health care helping to improve and maintain a good organ functionality, including vascular function, in health and disease.
- Conditions
- Endothelial Function, Aerobic Exercise, Middle-aged Adults Sedentary, Elevated CV-risk)
- Trial name
- VascuFit (NCT05235958)
- Testing
- non-linear periodized exercise (NLPE), Exercise counselling
- Where
- Switzerland
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Karsten Königstein
Behavior Change Interventions, Cardiovascular Diseases
Primary Care - Prescribing Lifestyle Adjustments for Cardiovascular Health
Prescribing lifestyle changes to patients who are at risk of cardiovascular disease, may be an extremely cost effective mechanism of improving health for the individual themselves and the NHS.
- Conditions
- Behavior Change Interventions, Cardiovascular Diseases, Cardiovascular Risk Factor, Behavior, Health
- Trial name
- P-PLAC 2 (NCT04113213)
- Testing
- Lifestyle Prescription (LRx)
- Where
- United Kingdom
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of South Wales
Smoking, Overweight
The Effect of a High Protein Diet Versus a Low Fat Diet on Body Weight After Smoking Cessation
The purpose of this study is to determine whether subjects following a high protein diet will gain less in weight after smoking cessation compared to subjects following a low fat diet due to the effects of protein on metabolic…
- Conditions
- Smoking, Overweight, Obesity
- Trial name
- NCT01069458
- Testing
- The high protein diet group and the low fat diet group
- Where
- Norway
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Intellectual Disability
Safer Online Lives: Use of the Internet & Social Media by People With Intellectual Disabilities
The objective of this study is to explore the benefits of internet use for people with intellectual disabilities (ID), the risks they might come up against while online, the barriers people with ID might come across due to the…
- Trial name
- SOL (NCT04919213)
- Where
- United Kingdom
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- University of Kent
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