Clinical trials: Risk Behavior
HIV Infections, Risk Reduction
Seroincidence Study Among Men Who Have Sex With Men and Transgender Women - The ImPrEP Seroincidence Study
PrEP (pre-exposure prophylaxis) is an effective prevention strategy in which HIV-negative individuals take antiretroviral drugs (tenofovir disoproxil fumarate and emtricitabine - TDF/FTC) to reduce HIV acquisition.
- Conditions
- HIV Infections, Risk Reduction, Risk Behavior, Risky Health Behavior
- Trial name
- Seroincidence (NCT05674682)
- Testing
- HIV testing
- Where
- 2 sites in Brazil
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Evandro Chagas National Institute of Infectious Disease
Cardiovascular Diseases (CVD), Cardiovascular Diseases Risk
Cardiovascular Health and Nursing Interventions in 6th Grade Middle School Children
Interventions that can improve cardiovascular health behaviors in children are of critical importance for reducing the burden of cardiovascular disease in the future.
- Conditions
- Cardiovascular Diseases (CVD), Cardiovascular Diseases Risk, Health Behavior, School Health Services
- Trial name
- NCT06812156
- Testing
- Cardiovascular Health Education
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ankara University
Smoking Cessation
Early Health Warning Intervention in Tobacco Control
This is a multi-center, randomized, controlled intervention clinical trial. A total of 1000 current smokers with rapid decline in lung function will be recruited and equally divided into two groups, comprehensive smoking…
- Trial name
- NCT04996329
- Testing
- early health warning intervention
- Where
- 10 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Obesity Prevention, Obesity
Effectiveness of Tailored Multichannel Interventions on Weight Loss Among Adolescents: A Randomized Controlled Trial
overweight among adolescents is a public health issue. However, several weight loss interventions were developed and conducted for adolescents.
- Conditions
- Obesity Prevention, Obesity, Overweight Adolescents, Overweight/Obesity, Adolescent
- Trial name
- NCT06767072
- Testing
- Tailored Multichannel interventions
- Where
- Egypt
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- Cairo University
Human Immunodeficiency Virus (HIV), Sexually Transmitted Disease (STD)
Steering Together in a New Direction: Reducing the Risk of HIV/STD Among African American Men
African American men have by far the highest rates of HIV in the US, but there are few randomized controlled trials (RCTs) of interventions to dissuade heterosexually active African American men from engaging sexual risk…
- Trial name
- STAND (NCT02572401)
- Testing
- STAND HIV Risk Reduction Intervention, Text Messaging Intervention
- Where
- United States
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Rheumatoid Arthritis, Chronic Kidney Diseases
Physical Activity and Cardiovascular Risk
Physical activity (PA) is essential for the prevention and treatment of chronic conditions. Despite its benefits, global physical inactivity is prevalent, contributing to chronic diseases and premature mortality.
- Conditions
- Rheumatoid Arthritis, Chronic Kidney Diseases, Endothelial Dysfunction, Arterial Stiffness
- Trial name
- PACaR (NCT06440369)
- Testing
- Training group, Physical activity orientation group
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Franche-Comté
Physical Activities, Cardiovascular (CV) Risk
Physical Inactivity Among Patients With Cardiovascular Risk
The goal of this clinical trial is to learn if newly developed intervention package works to improve physical activity level among patients with intermediate cardiovascular risk factors.
- Conditions
- Physical Activities, Cardiovascular (CV) Risk, Empowerment
- Trial name
- INSPIRE-PA (NCT07440056)
- Testing
- INSPIRE-PA intervention study arm
- Where
- Sri Lanka
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Colombo
Lifestyle Factors, Overweight and Obesity
Effect of Sleep Extension on Ceramides in People With Overweight and Obesity
The overall goal is to determine how a sleep extension intervention (increasing time in bed) in individuals who maintain less than 6.5 hours sleep per night affects their plasma ceramides and insulin sensitivity.
- Conditions
- Lifestyle Factors, Overweight and Obesity, Insulin Sensitivity, Eating Habit
- Trial name
- NCT06180837
- Testing
- Sleep Extension Intervention
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Utah
HIV Infections
PrEP Seguro: Antiretroviral-based HIV Prevention Among Men at High Risk in Mexico
The objective of this R34 application is to prepare for testing innovative user-centered ways to promote PrEP adherence at scale.
- Trial name
- NCT03674983
- Testing
- Conditional Economic Incentive (CEI)
- Where
- Mexico
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Brown University
Cardiovascular Risk Factor, Cardiovascular Diseases
Cardiovascular Risk in Toledo Population
This epidemiological and observational study is aimed to assess cardiovascular risk (CVR) by investigating the prevalence of CVR factors (CVRF), target organ damage (TOD) and cardiovascular disease (CVD) in general population of…
- Trial name
- RICARTO (NCT03294369)
- Testing
- Observational
- Where
- Spain
- Volunteers
- 3,125 people, healthy volunteers welcome
- Sponsor
- Castilla-La Mancha Health Service
Metabolic Syndrome, Protection Against
Personalised Advice for the Prevention of Metabolic Syndrome
Rationale: Improving dietary behaviours in view of optimising risk factors of metabolic syndrome requires behaviour change strategies. Tailored dietary advice, i.e.
- Trial name
- NCT04595669
- Testing
- Personalised advise
- Where
- Netherlands
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Wageningen University and Research
HIV Infections, Child Abuse, Sexual
Adult Sexual Risk Behavior Among Women With a History of Childhood Sexual Abuse
This study will evaluate whether childhood experiences are related to current sexual behavior of adult women.
- Trial name
- NCT00653575
- Testing
- Information-Motivation-Behavioral Skills model, Traumagenic Dynamics model
- Where
- United States
- Volunteers
- 481 people, healthy volunteers welcome
- Sponsor
- Syracuse University
Cascade Testing, Lynch Syndrome
Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch Syndrome
The purpose of the study is to see if our education materials help people at risk for Lynch syndrome decide about seeking genetic services.
- Conditions
- Cascade Testing, Lynch Syndrome, Decision Making, Colorectal Cancer
- Trial name
- NCT07106359
- Testing
- Information Letter and Booklet, Information Letter
- Where
- United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Gambling, Opioid
Treatment of Gambling Disorder With Fast Acting Opiate Antagonist, Naloxone Nasal Spray
Non-controlled pilot study. Two groups: Group A: naloxone nasal spray max 8 mg/per day; Group B: naloxone max 16 mg/per day. Study duration 8 weeks. Brief intervention.
- Conditions
- Gambling, Opioid, Naloxone, Spray
- Trial name
- NALPILO (NCT03223896)
- Testing
- Naloxone hydrochloride 20mg/ml
- Where
- Finland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare
Lifestyle Risk Reduction, Cholesterol, Elevated
Effect of a Customised Lifestyle Medicine Strategy on Lowering Blood Lipid Levels in Indian Physicians
Lifestyle medicine is a medical specialty that uses evidence-based therapeutic interventions to prevent, treat, and reverse chronic conditions.
- Conditions
- Lifestyle Risk Reduction, Cholesterol, Elevated, LDL Hyperlipoproteinemia, Hypertension
- Trial name
- CLIP (NCT06420817)
- Testing
- Indian version of a 'Portfolio' diet, Physical Activity, Intermittent fasting
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jubilee Mission Medical College and Research Institute
Caregiver, Caregiver Mental Health
Friends/Family of Individuals at Risk of Suicide Training Program
The Friends/Family of Individuals at Risk of Suicide Training (FIRST) program is a six-week program designed to provide knowledge and practical skills to help caregivers care for their loved one while also supporting their own…
- Conditions
- Caregiver, Caregiver Mental Health, Caregiver Stress, Suicide
- Trial name
- FIRST (NCT07902089)
- Testing
- FIRST Program
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention, Heart Disease
Social Work Intervention Focused on Transitions
In response to Program Announcement (PA)-09-164, "NIH Exploratory/Developmental Research Grant Program (R21) a randomized pilot study testing the efficacy of SWIFT: Social Work Intervention Focused on Transitions among at-risk…
- Conditions
- Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention, Heart Disease, Diabetes, Hypertension
- Trial name
- SWIFT (NCT02232126)
- Testing
- SWIFT home intervention
- Where
- 2 sites in United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Prematurity, Low Birth Weight
Paternal Involvement in Nursing Guidance and Breastfeeding Self-Efficacy in Mothers of High-Risk Newborns
This study aims to evaluate whether a structured nursing guidance program that increases fathers' participation in the care of hospitalized high-risk newborns improves maternal outcomes compared with routine nursing care.
- Conditions
- Prematurity, Low Birth Weight, Respiratory Distress Syndrome, Newborn, Neonatal Hyperbilirubinemia
- Trial name
- NCT07834008
- Testing
- step-by-step parent education, active father participation in breastfeeding support
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Familial Hypercholesterolemia
Effect of Breastfeeding on Lipid Profile and Cardiovascular Risk Markers in Women With Familial Hypercholesterolemia
The study aims to investigate the effects of breastfeeding on lipid profile and cardiovascular risk markers in women with familial hypercholesterolemia (FH) compared to women without FH.
- Trial name
- FH-FEMINA (NCT05367310)
- Where
- 4 sites in Czechia, Netherlands and 1 more
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Age Related Macular Degeneration
Life Style and Food Habits Questionnaire in the Portuguese Population Aged 55 or More
The study population will be selected from the "Epidemiological study on the prevalence of Age related Macular Degeneration in Portugal" (Protocol N.
- Trial name
- NCT01715870
- Testing
- Life style and food habits questionnaire
- Where
- Portugal
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Association for Innovation and Biomedical Research on Light and Image
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