Clinical trials: Risk Behaviors
Depression, Anxiety
Efficacy of a Brief Intervention to Improve Sexual and Gender Minorities' Mental Health: Randomized Controlled Trial.
Experiences of violence, from micro to physical aggressions, have a deleterious impact on mental health. According to the Minority Stress Theory, unfavorable social conditions (such as anticipated and experienced discrimination…
- Conditions
- Depression, Anxiety, Psychological Distress, Social Phobia
- Trial name
- ESCREVA-SE (NCT05349877)
- Testing
- Expressive writing, Self-affirmation
- Where
- Brazil
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Cardiovascular Risk Markers, Postprandial Metabolism
Exercise Intensity and Postprandial Effects of Breaking Sedentary Behavior in Overweight Adults
The purpose of this study is twofold: (1) to determine whether breaking up prolonged sitting with aerobic or sprint cycling breaks reduces postprandial blood glucose, insulin, CRP, and blood pressure, which are established risk…
- Conditions
- Cardiovascular Risk Markers, Postprandial Metabolism, Exercise Physiology, Substrate Oxidation
- Trial name
- NCT07229963
- Testing
- Aerobic Exercise Intervention, Sprint Exercise Intervention, Sedentary Behaviour Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Heart Disease Risk Factors, Healthy Lifestyle
Healthy Communities: A Healthy City Preventive Program on Cardiovascular Health and Well-being (HC)
Healthy Communities is a multidisciplinary health-promotion initiative. The objective of the present study is to determine whether such an intervention will be efficacious to improve cardiovascular health compared to the current…
- Conditions
- Heart Disease Risk Factors, Healthy Lifestyle, Health Behavior
- Trial name
- HC (NCT05974826)
- Testing
- the SI! Program for Secondary Schools (NCT03504059), the Fifty-Fifty Program (NCT02367963)
- Where
- Spain
- Volunteers
- 2,000 people
- Sponsor
- Foundation for Science, Health and Education, Spain
Dual Diagnosis, Risk Youth
Virtual Reality (VR-GINSO) as an Complement to Intervention for Alcohol and Cannabis Use in Youth in Residential Care
The goal of this RCT is to evaluate the effects of a virtual reality intervention on self-efficacy regarding alcohol and cannabis use among at-risk youth in various residential mental health treatment centers who have…
- Conditions
- Dual Diagnosis, Risk Youth, Antisocial Behavior
- Trial name
- VR-GINSO (NCT07834606)
- Testing
- Virtual Reality, Treatment as Usual (TAU)
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Universidad Francisco de Vitoria
Opioid Use Disorder, Infectious Disease
Addressing Risk Through Community Treatment for Infectious Disease and Opioid Use Disorder Now (ACTION) Among Justice-involved Populations
This is a 5-year Hybrid Type 1 Effectiveness-Implementation Randomized Control Trial (RCT) that compares two models of linking and retaining individuals recently released from justice involvement to the continuum of…
- Conditions
- Opioid Use Disorder, Infectious Disease, Risk Reduction Behavior, Substance Use
- Trial name
- ACTION (NCT05286879)
- Testing
- Patient Navigator, Mobile Health Unit
- Where
- 3 sites in United States
- Volunteers
- 601 people
- Sponsor
- Yale University
Heathly Subjects, Primary Health Care
Assessing the Effectiveness of Heat Adaptation Digital Messages From Primary Care Providers to Their Patients on the Change in Behaviour for Heatwave-related Preparedness
Extreme heat events pose a significant health threat in Canada, as demonstrated by the 2021 heat wave that claimed over 600 lives in Western Canada. Most heat-related deaths occur indoors and are preventable.
- Conditions
- Heathly Subjects, Primary Health Care, Climate Change, Public Health
- Trial name
- HeatSmart (NCT07024628)
- Testing
- Heat adaptation digital messaging, Non-heat-related digital messaging
- Where
- Canada
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Hopital Montfort
Cerebral Small Vessel Diseases, Dementia, Mixed
Dementia Risk Registry Across the Multidimensional Lifespan: A 10-Year Study
Age-related cerebral small-vessel disease (CSVD) is a major cause of dementia, predominantly affecting individuals over 60 years of age, with a prevalence exceeding 70% in the elderly population.
- Conditions
- Cerebral Small Vessel Diseases, Dementia, Mixed, Health Behavior, Health Behavior, Risky
- Trial name
- DREAM-10 (NCT06164262)
- Testing
- Individuals with CSVD
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Zhejiang Provincial People's Hospital
Alcohol Use Disorder, Risky Health Behavior
A Female-Specific CBT Group for Veteran Women With Alcohol Use Disorder in VA Primary Care Settings
The purpose of this study is to evaluate a Female-Specific Cognitive Behavioral Therapy (CBT) Group as treatment for Alcohol Use Disorder among Veteran women.
- Trial name
- NCT06118346
- Testing
- Female-Specific Cognitive Behavioral Therapy (FS-CBT), Usual Care
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- University of Massachusetts, Worcester
HIV, Substance Use Disorder (SUD)
Wellness, Intervention Strategies and HIV Care
This is a pilot trial designed to assess the feasibility and acceptability of an intervention aimed at improving adherence to antiretroviral therapy (ART), viral suppression, and engagement in HIV care.
- Trial name
- WISH (NCT07069374)
- Testing
- Wellness, Intervention Strategies and HIV Care (WISH), Movie Night Club - Attention and Time Matched Control
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- University of California, San Francisco
Dietary Behavior; Metabolic Health; Obesity; Lifestyle Modification; Metabolic Syndrome Risk
Agentic AI Personalized Dietary Management Study
This randomized controlled trial aims to evaluate the effectiveness of an Agentic AI-based personalized dietary management algorithm among adults undergoing health screening.
- Trial name
- AIDiet (NCT07638241)
- Testing
- Static AI-based personalized dietary goal setting, Adaptive AI-based personalized dietary management
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Opioid Use Disorder, Dual Diagnosis
Building Social and Structural Connections for the Prevention of Opioid Use Disorder Among Youth Experiencing Homelessness
Homelessness severely affects health and well-being and is particularly negative for youth. Between 70-95% of youth experiencing homelessness (YEH) report problem substance use and 66-89% have a mental health disorder.
- Conditions
- Opioid Use Disorder, Dual Diagnosis, Housing Problems, Mental Disorder in Adolescence
- Trial name
- NCT06311838
- Testing
- Motivational Interviewing/Community Reinforcement Approach (MI/CRA), Strengths-Based Outreach and Advocacy (SBOA ), Services as Usual (SAU)
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Ohio State University
Cardiovascular Diseases (CVD), Cardiovascular Diseases Risk
Cardiovascular Health and Nursing Interventions in 6th Grade Middle School Children
Interventions that can improve cardiovascular health behaviors in children are of critical importance for reducing the burden of cardiovascular disease in the future.
- Conditions
- Cardiovascular Diseases (CVD), Cardiovascular Diseases Risk, Health Behavior, School Health Services
- Trial name
- NCT06812156
- Testing
- Cardiovascular Health Education
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ankara University
Longitudinal Studies, Prospective Studies
Clinical Time and Temporal Dynamics Study (CLIN-TIME)
TH-CLINICAL-TIME is a prospective, longitudinal observational study evaluating how changes in clinical measurements over time may help researchers better understand patient health trajectories and clinically meaningful outcomes.
- Conditions
- Longitudinal Studies, Prospective Studies, Biomarkers, Predictive Value of Tests
- Trial name
- CLIN-TIME (NCT07812831)
- Testing
- No Study-Assigned Intervention
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Parenting, Mental Health Wellness 1
Parenting in 2 Worlds Multisite Trial
This research study will test the effectiveness of a culturally grounded parenting intervention called Parenting in 2 Worlds (P2W).
- Conditions
- Parenting, Mental Health Wellness 1, Substance Use, Risky Health Behavior
- Trial name
- (P2W) (NCT06324318)
- Testing
- Parenting in 2 Worlds (P2W), Healthy Families in 2 Worlds (HF2W)
- Where
- 4 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Sexual Risk Behavior for HIV-infection, Reproductive Health
Integrating PrEP Decision Making Into Counseling in Sexual and Reproductive Health Clinics
This study addresses the need for HIV prevention to be integrated into counseling visits at sexual and reproductive health clinics.
- Trial name
- NCT06684613
- Testing
- PrEP Decision Aid, Generic Information
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yale University
Communication, Message Perception
Messages That Motivate: Communicating Alcohol-Related Breast Cancer Risk to Young Adult Women
This is an online cross-sectional experimental survey study examining two cancer communication questions: 1) What features of social media messages communicating the breast cancer risks from alcohol consumption will motivate…
- Conditions
- Communication, Message Perception, Alcohol, Cancer Prevention
- Trial name
- MEMO (NCT07802054)
- Testing
- Risk Message, Efficacy Message, Industry Deception
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Health Adult Subjects, Exposure Occupational
French Military Firefighters to Assess Relationships Between Exposome and Health.
The aim of the study is to describe professional exposures and health events among French military firefighters (both active-duty personnel and veterans) and identify potential relationships between the exposome (the total…
- Conditions
- Health Adult Subjects, Exposure Occupational, Health Behavior, Risky, Occupational Health
- Trial name
- COMITEX-BSPP (NCT07270627)
- Where
- France
- Volunteers
- 1,811 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Healthy Aging, Exercise Therapy
Land vs. Water Exercises on Performance and Swimming Behavior in Older Adults
This study aims to investigate the effects of an 8-week combined land and aquatic exercise program (conducted 3 days per week) on physical performance, recreational swimming behaviors, and water-related risk perceptions in older…
- Conditions
- Healthy Aging, Exercise Therapy, Resistance Training, Hydrotherapy
- Trial name
- NCT07784205
- Testing
- 8-Week Beach and Aquatic Exercise Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Eskisehir Technical University
Nicotine Dependance, Serious Mental Illness
Evaluation of Community Health Worker Support to Help People With Serious Mental Illness to Quit Smoking
The purpose of this study is to learn whether providing additional smoking cessation support through specially trained members of behavioral healthcare team helps people quit smoking and improve their health.
- Conditions
- Nicotine Dependance, Serious Mental Illness, Smoking (Tobacco) Addiction, Tobacco Cessation
- Trial name
- NCT07789132
- Testing
- Integrated CHW Support intervention, Enhanced usual care (EUC)
- Where
- United States
- Volunteers
- 937 people
- Sponsor
- Massachusetts General Hospital
Risk Reduction, Environmental Exposure
Monitoring Environmental Exposures and Behavioral Change
The goal of this study is to examine what effect real-time feedback on particulate matter (PM) air pollution levels has on risk recognition and behavior.
- Conditions
- Risk Reduction, Environmental Exposure, Risk Behavior, Health
- Trial name
- NCT05338242
- Testing
- Real-Time Exposure Feedback
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Utah