Clinical trials: Risk Factors Cardiovascular Disease
Obesity, Insulin Resistance
Effects of Obesity and Intensity of Exercise on Ghrelin Levels
This study is investigating the effect of different intensities of exercise on levels of the hormone, ghrelin. In addition, we will be examining the relationship between any exercise induced changes in ghrelin and insulin…
- Conditions
- Obesity, Insulin Resistance, Cardiovascular Risk Factor
- Trial name
- NCT04581980
- Testing
- Exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Community Based Study, Cardiovascular Disease
Heart Rate, Baroreflex Sensitivity and Cardiovascular Morbidity and Mortality in the Population
The aim of the present Paris Prospective Study III (PPS3) is (1) to assess the determinants of the regulation of heart rate and blood pressure variations and carotid properties (under different physiologic stimulations) and (2)…
- Conditions
- Community Based Study, Cardiovascular Disease, Sudden Death, Blood Pressure
- Trial name
- PPSIII (NCT00741728)
- Testing
- Spider flash ECG, high-precision carotid echo-tracking, step test
- Where
- France
- Volunteers
- 10,157 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Obesity, Childhood, Diabetes Mellitus, Type 2
The QUebec Adipose and Lifestyle InvesTigation in Youth (QUALITY) Cohort
The QUebec Adipose and Lifestyle InvesTigation in Youth (QUALITY) Cohort study is a unique and comprehensive longitudinal study of 630 Caucasian children and their parents that was designed to investigate the natural history and…
- Conditions
- Obesity, Childhood, Diabetes Mellitus, Type 2, Cardiovascular Risk Factor, Pediatric ALL
- Trial name
- QUALITY (NCT03356262)
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Cardiovascular Disease
Effect of Trans Fatty Acids From Ruminant Sources on Risk Factors for Cardiovascular Disease
The objectives of this study are to : 1) determine if vaccenic acid (trans-11-octadecenoic, a naturally occurring trans fatty acid isomer from ruminant animal products) raises LDL cholesterol in a quantitatively comparable manner…
- Trial name
- NCT00942656
- Testing
- PHVO, CLA, VA
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- United States Department of Agriculture (USDA)
Metabolic Cardiovascular Syndrome
Metabolic Syndrome Diagnosis and Education Trial
This study is being done to gain knowledge on how effective different approaches of providing a diagnosis and varying educational tools that include DVDs and multimedia or printed instruction sheets on your readiness to increase…
- Trial name
- NCT00943254
- Testing
- High-Tech Education, Low-Tech Education
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Non-Communicable Diseases, Stroke
Make my Day - Primary Prevention of Stroke
The purpose of this study is to evaluate the feasibility of a digital, person-centered stroke prevention program with a focus on primary prevention.
- Conditions
- Non-Communicable Diseases, Stroke, Cardiovascular Risk Factor
- Trial name
- NCT03730701
- Testing
- Prevention program for stroke
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Emelie Malstam
Healthy Population
Italian Digital Primary Cardiovascular Prevention Study
The CV-PREVITAL study is a randomised clinical trial (RCT) controlled versus usual-care designed to compare the effectiveness of a mobile health (mHealth) intervention with that of usual care in reducing specific cardiovascular…
- Trial name
- CV-PREVITAL (NCT05339841)
- Testing
- Mobile health application
- Where
- 32 sites in Italy
- Volunteers
- 27,520 people, healthy volunteers welcome
- Sponsor
- Centro Cardiologico Monzino
Cardiovascular Disease
Effects of Almonds on Cardiovascular Risk Factors
The purpose of this research is to build the evidence base for approval of FDA health claims related to almonds and cardiovascular disease.
- Trial name
- ALD (NCT01101230)
- Testing
- Almonds
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Penn State University
Cardiovascular Diseases, Cardiovascular Risk Factor
Secondary Care - Prescribing Lifestyle Adjustments for Cardiovascular Health (S-PLAC 2)
Prescribing lifestyle changes to patients who have cardiovascular disease (CVD) may be an extremely cost effective mechanism of improving health individually and for the NHS.
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Health Behavior
- Trial name
- S-PLAC 2 (NCT04118673)
- Testing
- Lifestyle Prescription (LRx)
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of South Wales
Cardiovascular Risk Factors, Hypertension
Cardiovascular Health And Risk Modification in Family Health Teams
Cardiovascular diseases remain the main cause of mortality in Canada. While effective interventions are available for reducing the risk of cardiovascular disease,there continue to be gaps between the potential reduction in risk…
- Conditions
- Cardiovascular Risk Factors, Hypertension, Hyperlipidemia, Diabetes
- Trial name
- Multi-CHARM (NCT00787306)
- Testing
- Active risk factor surveillance
- Where
- Canada
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Cardiovascular Risk Factor, Pre Diabetes
Effects of a Workplace Exercise Intervention on Cardio-Metabolic Health
Background: The rising levels of physical inactivity in the Eastern Mediterranean region (43.2%) and in the United Arab Emirates (38%) compared with the global levels of physical inactivity (31.2%) is alarming (6,15).
- Conditions
- Cardiovascular Risk Factor, Pre Diabetes, High Blood Pressure, Elevated LDL Cholesterol
- Trial name
- NCT04403789
- Testing
- Exercise Time, Supervised Group Exercise
- Where
- United Arab Emirates
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- United Arab Emirates University
Cardiovascular Risk Factors, Insulin Resistance
Pilot Validation of the STELA Preventive Medicine Platform to Reduce Modifiable Health Risk Factors in Adults (CPM-STELA)
This study evaluates a comprehensive digital health platform called STELA, developed at the Center for Preventive Medicine (CPM) of AGEL Hospital Trinec-Podlesi in Czechia.
- Conditions
- Cardiovascular Risk Factors, Insulin Resistance, Obesity, Dyslipidemias
- Trial name
- CPM-STELA (NCT07551960)
- Testing
- STELA Digital Preventive Medicine Platform, Comprehensive Preventive Health Assessment
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nemocnice AGEL Trinec-Podlesi a.s.
Cardiovascular Disease, Metabolic Syndrome
Canola Oil Multi-center Intervention Trial II
Building on the findings from the investigators previous study, COMIT I, the purpose of the COMIT II study is to supplement the DEXA measurement of body composition with a supplementary DEXA measurement of visceral adipose tissue…
- Trial name
- COMITII (NCT03054779)
- Testing
- Canola Oil, High oleic acid canola oil, Western diet oil combination
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Penn State University
Type 2 Diabetes, Overweight
Effects of Caloric Restriction on Fetuin-A and Cardiovascular Risk Factors
The aim of this randomized controlled study was to evaluate the effects of CR on circulating fetuin-A levels in obese humans with type 2 diabetes based on monitoring energy intake and energy expenditure by daily activity.
- Trial name
- NCT01329822
- Testing
- Caloric restriction
- Where
- South Korea
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Korea University
Preeclampsia, Hypertension
Cardiac and Immune Cell Function in Preeclampsia
Preeclampsia is a multi-system vascular disease which affects 2-5% of pregnancies. It is also a risk factor for the development of cardiovascular disease later in life and a number of functional and structural cardiac changes…
- Conditions
- Preeclampsia, Hypertension, Pregnancy Induced Hypertension, Pregnancy Related
- Trial name
- NCT04508582
- Testing
- Cardiovascular magnetic resonance, Echocardiography, Blood test
- Where
- United Kingdom
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Cardiovascular Diseases, Acute MI
Impact of the Genetic Background as a Risk Factor for Atherosclerotic Cardiovascular Disease in the Brazilian Population
The main objective of this project is to evaluate the genomic information previously associated with cardiovascular diseases (CVD) and its importance as an independent risk predictor (expressed in Odds Ratio) when adjusted for…
- Conditions
- Cardiovascular Diseases, Acute MI, Stroke, Peripheral Arterial Disease
- Trial name
- CV-GENES (NCT05515653)
- Testing
- Exposure to genetics (polygenic)
- Where
- 41 sites in Brazil
- Volunteers
- 3,974 people, healthy volunteers welcome
- Sponsor
- Hospital Alemão Oswaldo Cruz
Cardiovascular Risk Factor, Nicotine Dependence
Vaping High vs. Low Nicotine E-Liquid
This study will examine the effects of electronic cigarette e-liquid nicotine content in a randomized, crossover clinical and behavioral pharmacology study of experienced adult e-cigarette users (N=36).
- Trial name
- NCT04047836
- Testing
- Low Nicotine E-Liquid, Medium or High Nicotine E-Liquid
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cardiovascular Health, Cardiovascular Risk Factors
The Effect of Women's Heart Health Awareness Program
The aim of this study is to examine the effect of a gender-specific heart health protection awareness program, incorporating video-supported reminder messages, on knowledge, attitudes, practices (KAP) regarding cardiovascular…
- Conditions
- Cardiovascular Health, Cardiovascular Risk Factors, Health Literacy
- Trial name
- NCT07502911
- Testing
- Heart Health Awareness Program
- Where
- Turkey (Türkiye)
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Lokman Hekim University
Blood Pressure
Effect of a Probiotic-based Product on Blood Pressure
The aim of the present study was to examine the efficacy of a probiotic-based product on either reducing hypertension or preventing a high normal blood pressure from reaching hypertensive levels.
- Trial name
- NCT01989702
- Testing
- Fermented blueberry drink, Sachets with probiotic bacterial powder
- Where
- Sweden
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Probi AB
Death, Carotid Artery Disease
NOR-SYS: The Norwegian Stroke in the Young Study
NOR-SYS is a clinical research program about young ischemic stroke patients from 15 to 60 years. Patients, partners and the couple´s adult children who are at least 18 years old, are all invited to ultrasound examinations due to…
- Conditions
- Death, Carotid Artery Disease, Cardiovascular Disease, Peripheral Artery Disease
- Trial name
- NOR-SYS (NCT01597453)
- Testing
- Lifestyle counseling
- Where
- Norway
- Volunteers
- 1,062 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital