Clinical trials: Risk Factors Cardiovascular Disease
Healthy Older Adults
Interactive Effects of Sodium and Potassium on Vascular Health in Older Adults
The goal of this clinical trial is to determine if a high potassium intake can counteract the harmful effects of excess sodium on endothelial function in older adults with no history of cardiometabolic disease.
- Trial name
- NCT07649005
- Testing
- low sodium/low potassium diet, high sodium/low potassium diet, high sodium/high potassium diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Florida State University
Stroke
Sex Differences in Vascular Markers of Stroke Risk
The purposes of this study are to quantify and compare vascular function in men and women, and to determine the effect of age, race-ethnicity, cardiovascular risk factors, biological markers and hormonal markers on vascular…
- Trial name
- SAVVY (NCT00681681)
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- Wake Forest University Health Sciences
Primary Graft Dysfunction, Lung Transplantation
Risk Factors That Increase the Chance of Developing Primary Graft Dysfunction After Lung Transplantation
Primary graft dysfunction (PGD) is a severe lung complication that can occur in the days after lung transplant surgery. This study will analyze blood samples to determine if high levels of certain chemicals may increase the risk…
- Trial name
- NCT00552357
- Where
- United States
- Volunteers
- 1,150 people
- Sponsor
- University of Pennsylvania
Hypertension, Dyslipidemia
Polypills Approach for Multiple Cardiovascular Risk Factors
The Polypill Approach for Multiple Cardiovascular Risk Factors (PACIF) trial is a multicenter randomized controlled trial that will test the effectiveness and safety of a fixed-dose combination strategy for the integrated…
- Conditions
- Hypertension, Dyslipidemia, Diabetes
- Trial name
- PACIF (NCT07679828)
- Testing
- Fixed-Dose Combination Strategy
- Where
- 15 sites in China
- Volunteers
- 8,252 people
- Sponsor
- China Medical University, China
Venous Congestion, Organ Dysfunction Syndrome
Venous Congestion and Organ Dysfunction.
Venous congestion, which is a phenomenon described in cardiology and post-operative cardiac surgery, is responsible for an increase in morbidity and mortality.
- Trial name
- CoDoRéa (NCT04680728)
- Testing
- collection of biological parameters, collection of echographic parameters, collection of clinical parameters
- Where
- France
- Volunteers
- 185 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Exercise, Cardiac Myosins
Changes in Adiponectin and Cardiovascular Disease Risk Factors in Overweight Patients
This study aimed to determine if eight-weeks of exercise-based cardiac rehabilitation could improve adiponectin and cardiovascular disease risk factors in overweight coronary heart disease patients.
- Conditions
- Exercise, Cardiac Myosins, Patients
- Trial name
- NCT02882672
- Testing
- Experimental, Control
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Isfahan
Coronary Heart Disease
Influencing Factors of Coronary Heart Disease in Young People
The incidence of coronary heart disease in young people is not uncommon and the investigators will explore the factors contributing to this outcome
- Trial name
- NCT05175495
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Hongzhuan Sheng
Patients With Coronary Artery Disease
Comparison Between HIIT and MICT on the Phase III of Cardiac Rehabilitation
The increase in the prevalence of cardiovascular diseases (CVD), directly associated with the aging of the population, is a concern for public health in Portugal.
- Trial name
- NCT03538119
- Testing
- High Intensity Interval Training Program, Moderate Intensity Continuous Training Program
- Where
- Portugal
- Volunteers
- 69 people
- Sponsor
- University of Évora
Cigarette Use, Alcohol Use Above Recommended Limits
Developing a Team-Delivered Intervention for Smoking and Hazardous Drinking for Primary Care Veterans With Cardiovascular Diseases
In this study, the investigators are interested in learning how patients feel about and are impacted by a new approach for the primary care team to use to talk to patients about heart disease and health behaviors.
- Conditions
- Cigarette Use, Alcohol Use Above Recommended Limits, Cardiovascular Risk Factors (e.g., Hypertension), Cardiovascular Diseases
- Trial name
- CARE (NCT05275582)
- Testing
- CARE
- Where
- 2 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cardiovascular Diseases, Thromboembolism
Risk Factors for Venous Thromboembolism in the Community
To evaluate the trends in the incidence of venous thromboembolism, to determine the risk factors for venous thromboembolism in patients with medical and surgical illness, and to evaluate the efficacy of the anticoagulant therapy…
- Trial name
- NCT00011180
- Where
- United States
- Volunteers
- 385 people
- Sponsor
- Mayo Clinic
Cardiac Surgery
Perioperative Cerebral Function Assessment for Cardiac Surgery
Perioperative neurological complications in cardiovascular surgical procedures are associated with a significant risk of mortality and disability.
- Trial name
- PEACE (NCT06660602)
- Testing
- cardiac surgery
- Where
- China
- Volunteers
- 1,845 people
- Sponsor
- China National Center for Cardiovascular Diseases
Obesity
Methods of Weight Loss in Overweight Coronary Patients
We hypothesize that a combination of high-caloric expenditure exercise and behavioral weight loss counseling would lead to a greater loss of fat mass and a greater improvement in cardiometabolic risk factors that standard (lower…
- Trial name
- NCT00628277
- Testing
- high caloric expenditure exercise, low caloric expenditure exercise plus dietary counseling
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Vermont
Trephined Syndrome, Sinking Skin Flap Syndrome
Prevalence of Trephined Syndrome After Decompressive Craniectomy
Decompressive craniectomy is frequently used to treat increased intracranial pressure or an intracranial mass effect. Trephined Syndrome describes a neurological deterioration, which is attributed to a large craniectomy.
- Conditions
- Trephined Syndrome, Sinking Skin Flap Syndrome, Traumatic Brain Injury, Stroke
- Trial name
- TS (NCT03186157)
- Testing
- Decompressive craniectomy, Cranioplasty
- Where
- Switzerland
- Volunteers
- 41 people
- Sponsor
- University Hospital, Geneva
Chronic Kidney Disease, Obesity
Weight Loss Interventions in Obese Patients With Stages 3-4 Chronic Kidney Disease: a Randomised Controlled Trial
Weight loss surgery is the most effective weight loss treatment available, but the direct effect on chronic kidney disease is less widely understood.
- Trial name
- NCT01053130
- Testing
- laparoscopic sleeve gastrectomy, weight management program
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- King's College Hospital NHS Trust
Carotid Artery Calcification, Periodontal Diseases
Assessment of Carotid Artery Calcifications
The aim of the study was to determine retrospectively the presence of carotid artery calcification (CAC) detected on digital panoramic radiographs (DPRs) and correlate the finding of such calcifications with gender, smoking…
- Trial name
- NCT04017078
- Testing
- diagnosis of carotid artery calcification on digital panoramic radiograph
- Where
- Turkey (Türkiye)
- Volunteers
- 1,101 people
- Sponsor
- Baskent University
Depression
Effectiveness of Nimodipine Plus Antidepressant Medication in Treating Vascular Depression
This study will examine whether combined use of an antidepressant medication and the medication nimodipine reduces risk of depression relapse in patients with vascular depression.
- Trial name
- NCT00781326
- Testing
- Nimodipine
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Pittsburgh
Transcatheter Aortic Valve Replacement, Coronary Artery Disease
Coronary Artery Disease Assessment Strategies in TAVI Patients
Coronary artery disease (CAD) and aortic stenosis frequently coincide. Before valve intervention, invasive coronary angiography is routinely performed to assess coronary status.
- Conditions
- Transcatheter Aortic Valve Replacement, Coronary Artery Disease, Heart Disease Risk Factors
- Trial name
- CAT (NCT06559332)
- Testing
- Risk-based CAD management, Invasive coronary angiography
- Where
- Switzerland
- Volunteers
- 546 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Coronary Occlusion/Thrombosis, Peptic Ulcer Hemorrhage
Systematic Screening for Risk-factors for Ulcer Bleeding Before Anti-thrombotic Treatment
In a prospective randomised study design to investigate, if a systematic risk factor screening for bleeding ulcer in patients, who following percutaneous coronary intervention (PCI) commence a one year combination treatment with…
- Trial name
- NCT01447498
- Testing
- Screening for risk factors for ulcer bleeding
- Where
- Denmark
- Volunteers
- 2,024 people
- Sponsor
- Odense University Hospital
Overweight and Obesity, Cardiovascular Risk Factors
Web-based Personal or Peer Group Weight Management Study
The PERGROUP trial aims to investigate whether Web-based personal or Web-based group counselling weight management program can help to achieve lifestyle changes needed for weight loss and improvement in quality of life and…
- Conditions
- Overweight and Obesity, Cardiovascular Risk Factors, Quality of Life, Work Ability
- Trial name
- PERGROUP (NCT03904160)
- Testing
- Weight management
- Where
- Finland
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of Turku
Cardiovascular Diseases, Inflammation
Dietary Intake of Alpha-linolenic Acid in Elderly
The purpose of this study is to evaluate the antiatherogenic and anti-inflammatory potential of an adequate intake of alpha-linolenic acid in elderly.
- Conditions
- Cardiovascular Diseases, Inflammation, Metabolism Disorder, Lipid
- Trial name
- NCT03025620
- Testing
- Rapeseed oil, Sunflower oil
- Where
- France
- Volunteers
- 254 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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