Clinical trials: Risk Factors Cardiovascular Disease
Atherosclerosis, Coronary Heart Disease
Genetics of Cardiovascular Disease
Participants are being recruited at the inpatient department of the National Medical Research Center of Cardiology on a 'all-comers' basis.
- Conditions
- Atherosclerosis, Coronary Heart Disease, Myocardial Infarction, Atrial Fibrillation
- Trial name
- GCVD (NCT06253481)
- Where
- 2 sites in Russia
- Volunteers
- 10,000 people
- Sponsor
- Center for Strategic Planning, of the Federal Medical and Biological Agency
Atherosclerotic Cardiovascular Disease (ASCVD), Chronic Kidney Disease (CKD)
The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)
The main purpose of this study is to determine if retatrutide can significantly lower the incidence of serious heart-related complications or prevent the worsening of kidney function.
- Trial name
- NCT06383390
- Testing
- Retatrutide
- Where
- 742 sites in United States, Argentina and 25 more
- Volunteers
- 10,000 people
- Sponsor
- Eli Lilly and Company
Obesity, Obesity, Abdominal
Effect of Balanced Hypocaloric Diet Associated With Supplementation of Eggplant Meal in the Remission of Cardiovascular Risk Factors
Cardiovascular diseases (CVD) prevail as the main cause of death in developed and developing countries and are among the most frequent causes of disabilities in Brazil and in the world.
- Trial name
- NCT01622309
- Testing
- eggplant meal, cassava meal
- Where
- Brazil
- Volunteers
- 363 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Healthy Volunteers
Impact of Cashew Nuts in the Human Diet: Measured Energy Value and Effects on Cardiovascular Disease Risk Factors
This study evaluates the effect of cashew nut consumption on traditional and emerging markers of cardiovascular disease (CVD) risk and determines the usable energy content of a serving of cashew nuts for accurate food labelling.
- Trial name
- NCT02628171
- Testing
- Base Diet, Base Diet with Cashew Nuts
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- USDA Beltsville Human Nutrition Research Center
Type 2 Diabetes, Glycemic Control
Latinos Understanding the Need for Adherence in Diabetes
The Latinos Understanding the Need for Adherence in Diabetes (LUNA-D) study, is a randomized controlled trial testing the effectiveness of an integrated behavioral health and primary care chronic care disease management…
- Conditions
- Type 2 Diabetes, Glycemic Control, Cardiovascular Risk Factors, Psychological Distress
- Trial name
- LUNA-D (NCT03983499)
- Testing
- Special Intervention
- Where
- United States
- Volunteers
- 456 people
- Sponsor
- San Diego State University
Cardiometabolic Risk Factors
Physical Exercise on Physiological Adaptation Capacity and Chronic Pain in Individuals With Cardiovascular Risk
This research focuses on studying the effects of a 12-week exercise program on the health of individuals at risk of heart disease.
- Trial name
- NCT06201273
- Testing
- High-Intensity Interval Training, Resistance Training
- Where
- Chile
- Volunteers
- 192 people
- Sponsor
- Universidad San Sebastián
Type 2 Diabetes
Italian Diabetes and Exercise Study 2
Current guidelines recommend supervised mixed (aerobic+resistance) physical activity to ensure optimal benefits to control blood glucose, lipids, blood pressure, and other cardiovascular risk and to minimize injuries.
- Trial name
- IDES-2 (NCT01600937)
- Testing
- Theoretical & practical exercise counseling
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Metabolic Fitness Association, Italy
Sudden Cardiac Death, Cardiomyopathies
Sudden Cardiac Death - Screening Of Risk Factors
The investigators have created a way of quickly collecting information in a large scale young population regarding the presence of some severity indicators that may allow us to classify them into: seemingly "low risk" and…
- Conditions
- Sudden Cardiac Death, Cardiomyopathies, Channelopathies
- Trial name
- SCD-SOS (NCT01845909)
- Testing
- ECG and survey screening
- Where
- Portugal
- Volunteers
- 15,351 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Stroke
Effects of Intravenous Laser Irradiation of Blood Treatment With Different Colored Lights on Controlling Recurrent Stroke Risk Factors and Neurological Function in Stroke Patients
Introduction and Purpose: Patients with stroke have over a decade of experience with vascular laser treatment. Previous studies predominantly used low-energy vascular lasers with red light, specifically helium-neon lasers with a…
- Trial name
- NCT06232499
- Testing
- Intravenous Laser Irradiation of Blood
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Hospital, Ministry of Health and Welfare
Healthy
Evaluation of Aging, Autonomic Nervous System Activity and Cardiovascular Events
The regulatory effects of the autonomic nervous system (ANS) concern almost all organs which permanently feed information back to this global biological vigilance system controlling allostasis.
- Trial name
- PROOF (NCT00759304)
- Where
- France
- Volunteers
- 1,011 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Sedentary, Cardiometabolic Syndrome
Effect of Interrupting Sedentary Time With Different Frequencies of Physical Activity on Cardiometabolic Risk Factors
The knowledge gap on sedentary behavior and sedentary breaks includes whether detrimental effects of sedentary behavior can be fully attenuated by 1.) sedentary breaks 2.) physical activity or 3.) both combined.
- Conditions
- Sedentary, Cardiometabolic Syndrome, Physical Activity
- Trial name
- NCT05622006
- Testing
- Sedentary breaks
- Where
- Norway
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Diabetes, Depression
INtegrating DEPrEssioN and Diabetes treatmENT (INDEPENDENT) Study
To provide better care and preventive services for people with both depression and diabetes, the investigators propose to develop and test whether interventions to reduce depressive symptoms can be integrated into routine…
- Conditions
- Diabetes, Depression, Cardiovascular Risk Factor
- Trial name
- INDEPENDENT (NCT02022111)
- Testing
- Patient Education and Behavioral Activation, Supporting Self-Care (care coordinators), Psychiatrist and Diabetologist Reviews
- Where
- 4 sites in India
- Volunteers
- 404 people
- Sponsor
- Emory University
COVID-19, Cardiovascular Diseases
The Global PCHF-COVICAV Registry
Background: Coronavirus disease (COVID-19) is a tremendous challenge the modern world has never seen before and is overwhelming the capacities of healthcare systems worldwide.
- Conditions
- COVID-19, Cardiovascular Diseases, Cardiovascular Risk Factor, Heart Failure
- Trial name
- PCHF-COVICAV (NCT04390555)
- Where
- Switzerland
- Volunteers
- 1,500 people
- Sponsor
- University of Zurich
Ischemic Stroke, Digital Health
Prevention of Ischemic Stroke Recurrence Using Digital Technology Application
The goal of this study is to find out whether a comprehensive management program that uses a smart bracelet and a mobile app can help people who have had an ischemic stroke (a type of stroke caused by a blocked blood vessel in…
- Trial name
- DESIRE (NCT07825311)
- Testing
- Digital Prevention Management, Usual Stroke Secondary Prevention Management
- Where
- China
- Volunteers
- 1,696 people
- Sponsor
- Affiliated Hospital of Nantong University
Testicular Cancer, Cardiovascular Diseases
Intermediate and Long Term Vascular Effects of Cisplatin in Patients With Testicular Cancer
Chemotherapy drugs improve cancer survival but increase the risk of cardiovascular disease (CVD). VEGF inhibitors (VEGFI) cause severe hypertension, while cisplatin appears pro-thrombotic.
- Conditions
- Testicular Cancer, Cardiovascular Diseases, Cardiovascular Risk Factor
- Trial name
- INTELLECT (NCT03557164)
- Where
- United Kingdom
- Volunteers
- 37 people
- Sponsor
- NHS Greater Glasgow and Clyde
Atrial Fibrillation
Atrial Fibrillation Trial To Eliminate Risk-factors
The goal of this prospective-enrolling cohort study is to test and observe the effect of an integrated multi-discipline care program in patients with atrial fibrillation. The main questions it aims to answer are: 1.
- Trial name
- AFTTER (NCT05718336)
- Testing
- Integrated care
- Where
- Taiwan
- Volunteers
- 343 people
- Sponsor
- National Taiwan University Hospital
Cannabis, Cardiovascular Risk Factor
Cannabis Inhalation: Effects on Cardiovascular Function During Rest and Exercise
This two-phase project seeks to examine the cardiovascular response to consumption of cannabis variants of different cannabinoid composition through different methods (smoking vs. vaporizing), at rest and during aerobic exercise.
- Trial name
- NCT04693884
- Testing
- Cannabis
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Jamie Burr
Cardiovascular Risk Factors (e.g., Hypertension)
Bicocca Epidemiological Assessment of Cardiovascular Risk Factors
The main objective of the study is to characterize the cardiovascular risk profile of the population in the Bicocca district through the evaluation of the exposome and the assessment of traditional and less studied cardiovascular…
- Trial name
- MUSA-BEA (NCT07207603)
- Testing
- No intervention
- Where
- Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Acute Stroke
Risk Factors of Conversion From Local to General Sedation in Endovascular Stroke Therapy
Thrombectomy is now the standard of care of revascularization in acute ischaemic stroke. Data tend to show that final neurologic outcome is superior if the thrombectomy procedure was performed under conscious sedation.
- Trial name
- AMAS (NCT02895776)
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Depression
Omega-3 for Depression and Other Cardiac Risk Factors - 2
The purpose of this 10 week randomized, placebo-controlled, double-blind clinical trial is to determine whether antidepressant augmentation with two grams of EPA omega-3 per day is superior to antidepressant therapy alone for…
- Trial name
- Omega-3(2) (NCT02021669)
- Testing
- Omega-3 supplement
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Washington University School of Medicine
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