Clinical trials: Risk Factors Cardiovascular Disease
Cardiovascular Risk Factors, Blood Pressure
Effect of a Specific Phenolic Compound on Blood Pressure
The study's main objective is to investigate the effects of acute consumption of a preparation containing 100 mg of a specific phenolic compound (patent pending, P201531587) on systolic BP after ingestion of a high fat meal.
- Trial name
- PHENOLPRESS (NCT02628353)
- Testing
- phenolic compound
- Where
- Spain
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Technological Centre of Nutrition and Health, Spain
Coronary Heart Disease, Stroke
Heart Disease on the Mend
The primary objective of this study was to evaluate the effectiveness of a multifactor cardiovascular disease (CVD) risk reduction program using team case management in high risk patients who have low family incomes and limited…
- Conditions
- Coronary Heart Disease, Stroke, Hyperlipidemia, Hypertension
- Trial name
- NCT00127751
- Testing
- Enhance health lifestyle changes and medication compliance
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Stanford University
Chronic Kidney Diseases, Diabetes Mellitus
Prevalence of Chronic Kidney Disease (CKD) and Risk Factors in Sub-Saharan Africa
Prospective cross-sectional study at the outpatient clinic (OPC) of the Bagamoyo District Hospital (BDH) in Tanzania. Assessment of basic epidemiological data (Point prevalence and risk factors) on CKD with simple clinical…
- Conditions
- Chronic Kidney Diseases, Diabetes Mellitus, Hypertension, Tuberculosis
- Trial name
- RenalOne (NCT03458338)
- Testing
- estimated glomerular filtration rate and albuminuria
- Where
- Switzerland
- Volunteers
- 1,006 people
- Sponsor
- University Hospital, Basel, Switzerland
Breast Cancer Females
Chronic Impacts of Endocrine Therapy on Cardiovascular and Brain Health Outcomes in Breast Cancer
Aromatase inhibitors are the most used endocrine therapy for hormone-positive breast cancer. Despite the evidence that aromatase inhibitor therapy is associated with increased risk of cardiovascular events, potentially related to…
- Trial name
- STRIVE-Chronic (NCT06776458)
- Testing
- N/A - Usual Care
- Where
- Canada
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Intracranial Atherosclerosis
Asymptomatic Intracranial Atherosclerotic Disease in Pakistanis
The incidence of stroke has increased by 100% in the last four decades in developing countries like Pakistan. Intracranial atherosclerotic disease (ICAD) is the most frequent causative subtype of ischemic stroke in the world…
- Trial name
- AICAD (NCT02072876)
- Where
- 2 sites in Pakistan
- Volunteers
- 200 people
- Sponsor
- Aga Khan University
Gender Incongruence, Cardiovascular (CV) Risk
Cardiovascular Health of Transgender Individuals During the Gender-affirming Pathway
Gender incongruence, now classified in ICD-11 as a "marked and persistent incongruence between an individual's experienced gender and the gender assigned at birth," is managed in dedicated, multidisciplinary centres that…
- Conditions
- Gender Incongruence, Cardiovascular (CV) Risk, Cardiovascular Disease Risk Factor, Cardiovascular Disease Acute
- Trial name
- CV-TGD (NCT07187947)
- Testing
- Feminizing GAHT, Masculinizing GAHT
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Stroke
A TargEted MAnageMent Intervention for Reducing Stroke Risk Factors in High Risk Ugandans
The proposed 2-phase project will first refine the TargetEd MAnageMent (TEAM) intervention to ensure acceptability across a broad range of Ugandans at risk for stroke and then test the effects of TEAM in reducing stroke risk in a…
- Trial name
- TEAM-U (NCT04685408)
- Testing
- TEAM, ETAU
- Where
- 3 sites in Uganda
- Volunteers
- 276 people
- Sponsor
- Case Western Reserve University
Cardiovascular Risk Factor
A Mechanistic Randomized Controlled Trial on the Cardiovascular Effect of Berberine
Berberine is extracted from Coptis (Huanglian) and Phellodendron Chinese (Huangbai), to make into berberine tablets.1 Recent studies have shown that berberine has beneficial effects on cardiovascular disease (CVD) risk…
- Trial name
- NCT03770325
- Testing
- Berberine
- Where
- Hong Kong
- Volunteers
- 84 people
- Sponsor
- The University of Hong Kong
Acute Ischemic Stroke
An Application Provides Personalized Suggestions Based on Secondary Prevention Risk Factors to Stroke Patients
This study applied an application that provides personalized suggestions and explore the effect of this actual intervention on reducing the risk of stroke recurrence
- Trial name
- NCT07098143
- Testing
- Risk factor management
- Volunteers
- 5,092 people
- Sponsor
- Xuanwu Hospital, Beijing
Lung Neoplasms, Venous Thromboembolism
Venous Thromboembolism in Advanced Lung Cancer
This is a prospective observatory clinical study, aiming to establish and validate venous thromboembolism risk model in Chinese advanced non-small cell lung cancer.
- Trial name
- RIVAL (NCT03581708)
- Testing
- lung cancer
- Where
- China
- Volunteers
- 1,400 people
- Sponsor
- Guangdong Provincial People's Hospital
Cardiovascular Risk Factors
Echocardiography Management for Patients Requiring Care for Non-Cardiac Surgery
The growing population of institution patients with heart failure combined with the increasing number of surgical procedures performed each year supports the need for a critical analysis of how to most appropriately manage these…
- Trial name
- EGHEM (NCT01050361)
- Testing
- Transthoracic Echocardiogram (TTE)/Transesophageal Echocardiogram (TEE)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Sudden Cardiac Death Due to Cardiac Arrhythmia, Dilated Cardiomyopathy
Arrhythmic Risk Stratification in Nonischemic Dilated Cardiomyopathy
Nonischemic dilated cardiomyopathy is a heterogeneous disease often associated with increased rates of sudden cardiac death. Although many algorithms have been proposed, risk stratification remains suboptimal, and implantable…
- Trial name
- ReCONSIDER (NCT04246450)
- Testing
- Implantable Cardioverter Defibrillator (ICD) insertion
- Where
- Greece
- Volunteers
- 675 people
- Sponsor
- University of Athens
Prediabetic State, Metabolic Syndrome
Effects of Sweetener Consumption on Risk Factors for Heart Disease in Prediabetic Subjects
The aim of this prospective interventional study is to investigate the metabolic effects of consuming artificial and natural sweeteners in persons with prediabetes.
- Conditions
- Prediabetic State, Metabolic Syndrome, Insulin Resistance, Thrombosis
- Trial name
- Sweetheart (NCT07377097)
- Testing
- Saccharin, Sucralose, Erythritol
- Volunteers
- 80 people
- Sponsor
- Charite University, Berlin, Germany
Overweight, Obesity
Evaluation of a New Orange-Based Beverage Enriched With Polyphenols in Adult Humans
The purpose of this study is to evaluate the effects of a new orange juice-based beverage enriched in fiber and selected phenolic compounds (mainly flavanones) on features of metabolic syndrome and cardiovascular disease risk…
- Trial name
- BIONAOS (NCT01290250)
- Testing
- Orange juice based beverage enriched in polyphenols
- Where
- Spain
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- The Coca-Cola Company
Minor Head Injury, Intracranial Bleeding
Risk Factors of Minor Head Injury
Introduction and Aims: The objective of this prospective study is to evaluate the risk factors of minor head injury in all consecutive patients of one year.
- Conditions
- Minor Head Injury, Intracranial Bleeding, Traumatic Brain Injury
- Trial name
- NCT00451789
- Where
- Austria
- Volunteers
- 12,500 people
- Sponsor
- Medical University of Vienna
Metabolic Syndrome
Dose Ranging Study of the Effects of Alpha Lipoic Acid on Oxidative Stress
Heart disease is the most common cause of death in the United States and it is commonly found in people with diabetes and high cholesterol.
- Trial name
- Alpha (NCT00857376)
- Volunteers
- 77 people
- Sponsor
- Johns Hopkins University
Hypertrophic Cardiomyopathy (HCM)
Identification of Risk Factors for Arrhythmia in Children and Adolescents With Hypertrophic Cardiomyopathy
This study will review medical information collected on children and adolescents with hypertrophic cardiomyopathy (HCM) to try to identify risk factors for arrhythmias (abnormal heart rhythms) in these patients and better guide…
- Trial name
- NCT00753233
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Heart Failure, Metabolic Cardiovascular Syndrome
Cardiometabolic evalUation REgistry of Heart Failure
This is a combined retrospective-prospective observational cohort study investigating the role of systemic and local cardiometabolic risk factors in cardiac structural/functional remodeling and clinical outcomes among heart…
- Conditions
- Heart Failure, Metabolic Cardiovascular Syndrome, Metabolic Diseases
- Trial name
- CURE-HF (NCT06939985)
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Ruijin Hospital
Cardiovascular Disease, High Blood Pressure
Using Practice Facilitation in Primary Care Settings to Reduce Risk Factors for Cardiovascular Disease
The primary purpose of this study is to evaluate the effectiveness of practice facilitation as a quality improvement strategy for implementing the Million Hearts' ABCS treatment guidelines for reducing cardiovascular disease…
- Trial name
- NCT02646488
- Testing
- Million Hearts ABCS 6 Months, Million Hearts ABCS 9 Months, Million Hearts ABCS 12 Months
- Where
- United States
- Volunteers
- 276 people
- Sponsor
- NYU Langone Health
Stress Reaction; Acute
Racial Discrimination and Stress Response
The goal of this study is to learn about whether ethnic minority adolescents' racial discrimination experience is related to dysregulated biological responses to subtle racism, and how the relationship may be attenuated or…
- Trial name
- NCT05820659
- Testing
- peer rejection task, conversation about peer rejection, and impossible puzzle task
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Western Kentucky University
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