Clinical trials: Risk Factors Cardiovascular Disease
Coronary Artery Disease
Coronary Artery Disease: a Case- Control Study
Atherosclerosis is a chronic inflammatory condition, which is associated by the involvement of several pathological events, and alteration in the serum levels of pro- and anti-inflammatory, and lipid markers.
- Trial name
- NCT03075566
- Testing
- Healthy subjects, Patients
- Where
- Tunisia
- Volunteers
- 517 people, healthy volunteers welcome
- Sponsor
- Nadia Bouzidi, PhD
Cardiovascular Diseases, Cardiovascular Risk Factor
Chinese Multi-provincial Cohort Study-Beijing Project
The Chinese Multi-provincial Cohort Study (CMCS)-Beijing project is a sub-study in CMCS participants from Beijing, which intended to investigate the progression and determinants of atherosclerosis and aging related health…
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Aging Problems, Smell Disorder
- Trial name
- CMCS-Beijing (NCT04253054)
- Testing
- Cardiovascular risk factors, Aging related health problems
- Where
- 3 sites in China
- Volunteers
- 3,000 people
- Sponsor
- Beijing Institute of Heart, Lung and Blood Vessel Diseases
Blood Pressure
Effect of a Probiotic-based Product on Blood Pressure
The aim of the present study was to examine the efficacy of a probiotic-based product on either reducing hypertension or preventing a high normal blood pressure from reaching hypertensive levels.
- Trial name
- NCT01989702
- Testing
- Fermented blueberry drink, Sachets with probiotic bacterial powder
- Where
- Sweden
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Probi AB
Psoriasis, Cardiovascular Diseases
Prevalence and Risk Factors asSOciated With CArdiac comorbiDIty in psoriAsis
In a prospective cohort study (n = 1.000), the investigators aim to investigate the correlation between cardiac biomarkers and advanced echocardiography and determine whether these are prognostic markers of heart disease in…
- Conditions
- Psoriasis, Cardiovascular Diseases, Cardiovascular Risk Factor, Cardiovascular Pathology
- Trial name
- PSOCADIA (NCT04950218)
- Where
- Denmark
- Volunteers
- 1,000 people
- Sponsor
- Herlev and Gentofte Hospital
Vascular Thrombosis
Is Red Blood Cell Transfusion a Risk Factor for Vascular Pedicle Thrombosis? The Study Case of a Latin American Cohort
The present cohort was performed between January of 2014 and December of 2019. It included 302 free flaps conducted between January 2006 and December 2019 in the Hospital de San José and Hospital Infantil Universitario de San…
- Trial name
- RBCT (NCT04860544)
- Testing
- RED BLOOD CELLS TRANFUSION
- Volunteers
- 302 people
- Sponsor
- Fundación Universitaria de Ciencias de la Salud
Panic Disorder, Generalized Anxiety Disorder
Physical and Psychological Health Trajectories in the Context of Coronary Heart Disease
The primary aim of this study is to establish how frequently patients with coronary artery disease present or develop two anxiety disorders (panic disorder and generalized anxiety disorder) in the two years following a medical…
- Conditions
- Panic Disorder, Generalized Anxiety Disorder, Coronary Artery Disease, Anxiety Disorders
- Trial name
- NCT04433832
- Where
- Canada
- Volunteers
- 3,610 people
- Sponsor
- Laval University
Coronary Heart Disease, Cardiovascular Risk Factor
Individual Variability of Coronary Heart Disease Risk Markers and Sleep Responses to Exercise
The aim of this study is to examine the reproducibility of postprandial coronary heart disease (CHD) risk marker and sleep responses to acute exercise bouts and to quantify the magnitude of individual variability in responses…
- Conditions
- Coronary Heart Disease, Cardiovascular Risk Factor, Arterial Stiffness, Blood Pressure
- Trial name
- NCT05022498
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Psoriasis, Psoriatic Arthritis
SystemIc iNflammation and Microvascular diSease PreventIon in psoRiatic diseasE
This is a single-label open-arm mechanistic clinical study recruiting patients with psoriasis or psoriatic arthritis with elevated cardiovascular risk.
- Conditions
- Psoriasis, Psoriatic Arthritis, Cardiovascular Risk Factor
- Trial name
- INSPIRE (NCT04417114)
- Testing
- Rosuvastatin
- Sponsor
- Brigham and Women's Hospital
Cardiovascular Disease
Cardiovascular Prophylaxis for Postmenopausal Women
The purpose of this study was to examine the effect of 6 months moderate intensity exercise training completed three times per week upon traditional and emerging cardiovascular disease risk factors in postmenopausal women both…
- Trial name
- NCT01219725
- Testing
- Exercise training
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Obesity, Overweight
Cardiovascular Outcomes Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects With Cardiovascular Risk Factors (The Light Study)
The purpose of this study is to determine the effects of NB relative to placebo on major adverse cardiovascular events (MACE) such as cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke in overweight and…
- Trial name
- NCT01601704
- Testing
- NB32, PBO, Weight Management Program
- Where
- 224 sites in United States
- Volunteers
- 8,910 people
- Sponsor
- Orexigen Therapeutics, Inc
Obesity & Overweight, Weight Loss
GLP-1 Medication & Behavioral Health Programs on Weight & Metabolic Outcomes: FLOURISH and THRIVE Prospective Cohort Study
This research program includes two coordinated prospective studies (FLOURISH and THRIVE) evaluating the real-world effectiveness of Noom's digital health programs on weight, cardiometabolic biomarkers, physiological health…
- Conditions
- Obesity & Overweight, Weight Loss, Preventative Health, Body Weight
- Trial name
- FLOURISH (NCT07588984)
- Testing
- Noom Weight, Free Tier, Education-only control
- Where
- United States
- Volunteers
- 2,310 people
- Sponsor
- Noom Inc.
HIV-1 Infection, Cardiovascular Disease
Reducing Cardiovascular Disease (CVD) Risk in HIV on Antiretroviral Therapy Over 12 Months
This is a cohort study which follows two groups of participants over a 12 months period. One group will access a team approach to care with the aim of reducing their cardiovascular disease (CVD) risks from a team of doctors…
- Trial name
- CVD (NCT01436136)
- Testing
- Control, Intervention Group
- Where
- Australia
- Volunteers
- 92 people
- Sponsor
- Holdsworth House Medical Practice
Obesity, Obesity, Abdominal
Effect of Balanced Hypocaloric Diet Associated With Supplementation of Eggplant Meal in the Remission of Cardiovascular Risk Factors
Cardiovascular diseases (CVD) prevail as the main cause of death in developed and developing countries and are among the most frequent causes of disabilities in Brazil and in the world.
- Trial name
- NCT01622309
- Testing
- eggplant meal, cassava meal
- Where
- Brazil
- Volunteers
- 363 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Coronary Artery Disease, Percutaneous Coronary Intervention
Evaluation of Novel Risk Factors and Clinical Outcomes of Acute Myocardial Infarction
The aim of this study is to investigate the potential novel risk factors for acute myocardial infarction. Predictors of poor outcomes will be also evaluated.
- Conditions
- Coronary Artery Disease, Percutaneous Coronary Intervention, Acute Myocardial Infarction
- Trial name
- NCT02641184
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Zhejiang Provincial People's Hospital
Intracranial Sacciform Aneurysm
Evaluation of Intestinal Microbiota Implication in Ruptured Intracranial Aneurysm
The physiopathology of intracranial aneurysm from initiation to ruptured is incompletely understood but included inflammation. The microbiota is known to interact with brain and can promote inflammation.
- Trial name
- AneBiote (NCT05914636)
- Testing
- analysis of foecal microbiota
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon
Periodontitis, Adult
Effects of Antibiotic Therapy on the Short and Long-term Results of Periodontitis Treatments
Antibiotics are currently used in periodontology to specifically target the most pathogenic bacteria in subgingival biofilms and to improve treatments.
- Trial name
- PERIODONTITIS (NCT05065034)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Psoriasis, Cardiovascular Disease
Psoriasis and the Risk of Cardiovascular Disease. A Prospective Study
There is growing evidence that psoriasis is a systemic disorder which enhances atherosclerosis and the risk of cardiovascular disease.
- Trial name
- NCT01382784
- Where
- 2 sites in Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Coronary Atherosclerosis
STRADIVARIUS (Strategy To Reduce Atherosclerosis Development InVolving Administration of Rimonabant - the Intravascular Ultrasound Study)
The purpose of this study is to determine if rimonabant 20 mg once daily (od) administered during 18-20 months will reduce progression of coronary atherosclerosis as assessed by intravascular ultrasound (IVUS) when administered…
- Trial name
- NCT00124332
- Testing
- Rimonabant (SR141716)
- Where
- 9 sites in United States, Australia and 7 more
- Volunteers
- 839 people
- Sponsor
- Sanofi
Coronary Heart Disease
A Programme Using a Mobile Application Versus Phone Advice on Patients at Risk of Coronary Heart Disease - A RCT
It aims to compare the effects of a professional -led support programme using a mobile application versus telephone advice on clients at risk of coronary heart disease.
- Trial name
- NCT04968067
- Testing
- App group, Nursing telephone advice (NTA) group
- Where
- Hong Kong
- Volunteers
- 168 people
- Sponsor
- The Hong Kong Polytechnic University
Atrial Fibrillation, Atrial Fibrillation Paroxysmal
Early Diagnosis of Atrial Fibrillation in the Wait-Time Prior to Seeing a Cardiologist
A randomized patient-oriented trial to investigate whether continual symptomatic use of the Kardia Mobile monitoring device is a superior strategy for diagnosing Atrial Fibrillation (AF) in comparison to normal ambulatory…
- Conditions
- Atrial Fibrillation, Atrial Fibrillation Paroxysmal, Arrhythmias, Cardiac, Cardiovascular Diseases
- Trial name
- CATCH-AF (NCT04302311)
- Testing
- Holter monitoring, Kardia/AliveCor monitoring
- Where
- Canada
- Volunteers
- 73 people
- Sponsor
- Victoria Cardiac Arrhythmia Trials
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