Clinical trials: Risky Substance Use
Risk Behavior, Alcohol Use Disorder
TRAC-ER Intervention to Reduce Risky Alcohol Use and HIV Risk
Ecological momentary interventions (EMI), which use phones to deliver messages to reduce alcohol use and related risk behaviors during or prior to drinking events, can help to address triggers in real-time.
- Conditions
- Risk Behavior, Alcohol Use Disorder, HIV Infections
- Trial name
- TRAC-ER (NCT05576350)
- Testing
- Smartphone Based Alcohol Monitoring (SAM), Tracking and Reducing Alcohol Consumption (TRAC), TRAC-ER
- Where
- 2 sites in United States
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- University of Kentucky
Alcohol, Drinking, Alcohol Use Disorder
Sustaining Patient-centered Alcohol-related Care
Alcohol use is the third greatest cause of disability and death for US adults. Care for unhealthy alcohol use is lacking in most primary care settings.
- Trial name
- SPARC (NCT02675777)
- Testing
- Quality Improvement Intervention
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Parenting, Mental Health Wellness 1
Parenting in 2 Worlds Multisite Trial
This research study will test the effectiveness of a culturally grounded parenting intervention called Parenting in 2 Worlds (P2W).
- Conditions
- Parenting, Mental Health Wellness 1, Substance Use, Risky Health Behavior
- Trial name
- (P2W) (NCT06324318)
- Testing
- Parenting in 2 Worlds (P2W), Healthy Families in 2 Worlds (HF2W)
- Where
- 4 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Binge Drinking, Problematic AOD Use
Two Consecutive Randomized Controlled Trials Using Mobile Phone Applications for Risky Alcohol Use
The purpose of this study is to evaluate the efficacy of three mobile phone applications, Promillekoll, PartyPlanner and TeleCoach among university student union members with problematic drinking.
- Trial name
- NCT02064998
- Testing
- Promillekoll, PartyPlanner, TeleCoach
- Where
- Sweden
- Volunteers
- 2,166 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Microbiome Analysis, Drug Abuse in Pregnancy
Alcohol and Cannabis Use Among Pregnant Slovenian Women
The aim of the study is to determine the prevalence of alcohol and drug use among Slovenian pregnant women. Alcohol and drug use during pregnancy has significant effects on the foetus and has short- and long-term health…
- Conditions
- Microbiome Analysis, Drug Abuse in Pregnancy, Alcohol Abuse in Pregnancy, Health Behavior, Risky
- Trial name
- NCT07456579
- Where
- Slovenia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Substance Abuse, Mental Health
Optimizing a Drug Abuse Prevention Program for Dissemination
This project is a hybrid efficacy/effectiveness trial of a streamlined version of the Bridges program, an evidence-based intervention (EBI) to prevent substance abuse and mental health disorders.
- Conditions
- Substance Abuse, Mental Health, Educational Problems
- Trial name
- Bridges (NCT03125291)
- Testing
- Bridges 4-week Program
- Where
- United States
- Volunteers
- 664 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Violence, Substance Use
Project IntERact Study
This study will use a randomized control trial design (RCT) to pilot test a multisession remote therapy behavioral intervention for risky firearm behaviors and associated behaviors/consequences among adolescents.
- Conditions
- Violence, Substance Use, Criminal Behavior
- Trial name
- NCT03940716
- Testing
- IntERact
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Opioid Use Disorder, Healthy Volunteers
Measuring the Effects of Neurostimulation on Risky and Ambiguous Decision-Making Capacity in People With and Without Substance Use Disorder
Background: The purpose of this study is to understand how a type of brain stimulation, transcranial magnetic stimulation (TMS), may help those who use opioids such as heroin or methadone.
- Trial name
- NCT06577454
- Testing
- TMS (MagVenture MagPro 100 with MagOption)
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Risky Health Behavior, Substance Use Disorders
The STop UNhealthy Substance Use Now Trial
The STop UNhealthy (STUN) Substance Use Now Trial (STUN II) is a multisite trial aiming to evaluate the comparative effectiveness of the following strategies for improving the implementation of screening and interventions for…
- Conditions
- Risky Health Behavior, Substance Use Disorders, Substance Abuse, Alcohol Use Disorder
- Trial name
- STUN II (NCT06524232)
- Testing
- Practice Facilitation (PF), Learning Collaborative (LC), Performance Incentives (PI)
- Where
- 3 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Substance-Related Disorders
Peer MI for Substance-using Emerging Adults
The main purpose of this project is to test whether Peer-Enhanced Motivational Interviewing (PMI) results in superior alcohol and marijuana use outcomes for emerging adults (EAs, ages 18-29) and their peers.
- Trial name
- NCT03264872
- Testing
- Peer-Enhanced Motivational Interviewing, Waitlist Control
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Addictive Behavior, Alcohol Use Disorder
90-Day Online Substance Use Program
Individuals indicating risky substance use are randomly assigned either to a three-month online intervention on the Workit Health platform or a waitlist/treatment as usual.
- Conditions
- Addictive Behavior, Alcohol Use Disorder, Alcohol Abuse, Drug Abuse
- Trial name
- NCT03069118
- Testing
- Treatment - Workit Health Online Program, Control - Resource List
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Workit Health
Emotion Regulation Difficulties; Risky Behaviors (Substance Use, Risky Sexual Behavior, Self-harm, Aggression, Disordered Eating)
The Effects of the PsyPills App on Emotion Regulation and Risk Behaviors in Emerging Adults: A Randomized Clinical Trial
This study aims to investigate the effects of the PsyPills mobile application on improving emotion regulation and reducing risk behaviors among emerging adults.
- Trial name
- NCT07304830
- Testing
- PsyPills, MoodWheel
- Where
- Romania
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Substance Abuse, Risk Reduction
First Years Away From Home: Letting Go and Staying Connected
Alcohol abuse is the leading cause of death and serious injury among college students, and students also experience significant harms from other types of substance misuse and risk behaviors.
- Conditions
- Substance Abuse, Risk Reduction, RIsky Sexual Behavior
- Trial name
- FYAH:LGSC (NCT03227809)
- Testing
- Handbook condition, Handbook plus condition
- Where
- United States
- Volunteers
- 910 people, healthy volunteers welcome
- Sponsor
- Washington State University
Risky Health Behavior, Drinking, Alcohol
STUN (STop UNhealthy) Alcohol Use Now! Implementing Evidence-Based Services for Unhealthy Alcohol Use in Primary Care
STUN Alcohol Use Now is an intervention designed to use primary care practice support services (practice facilitation) to help small to medium-size practices (10 or fewer providers) identify and provide services for people with…
- Conditions
- Risky Health Behavior, Drinking, Alcohol, Alcohol Use Disorder, Drinking, Binge
- Trial name
- STUN (NCT04317989)
- Testing
- Practice Facilitation
- Where
- 7 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Relationship, Family (Foster), Substance Use Prevention
A Trial of Connecting to Promote Foster Teen Well-Being
This study evaluates the efficacy of a self-directed parenting program called Connecting in reducing risk of substance use and other risky behaviors in young foster teens (ages 11-15).
- Trial name
- NCT03157895
- Testing
- Connecting
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Washington
Substance Abuse, Juvenile Delinquency
The Community Youth Development Study: A Test of Communities That Care
The Community Youth Development Study is an experimental test of the Communities That Care (CTC) prevention planning system. It has been designed to find out if communities that were trained to use the CTC system improved public…
- Conditions
- Substance Abuse, Juvenile Delinquency, Sexual Behavior, Criminal Behavior
- Trial name
- CYDS IV (NCT01088542)
- Testing
- Communities That Care
- Where
- United States
- Volunteers
- 52,323 people, healthy volunteers welcome
- Sponsor
- University of Washington
Sexual Assault, Substance Use
Nexus of Risk: Sexual Assault, Alcohol Use, and Risky Sex Among College Women
Sexual assault on college campuses has reached epidemic proportions, yet the etiological variables responsible for violence against women in these contexts remain unclear.
- Conditions
- Sexual Assault, Substance Use, Risky Health Behavior, Ema
- Trial name
- NCT05892692
- Testing
- Ecological Momentary Intervention
- Where
- United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Alcohol, Drinking
Michigan SPARC Trial
Unhealthy alcohol use is a major contributor to morbidity and mortality in the US. Although effective prevention for unhealthy alcohol use and medication treatment for alcohol use disorders (AUDs) can be provided in primary care…
- Conditions
- Alcohol, Drinking, Alcohol Use Disorder (AUD)
- Trial name
- MI-SPARC (NCT04861792)
- Testing
- Michigan SPARC Quality Improvement Intervention
- Where
- United States
- Volunteers
- 9,590 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Alcohol Drinking, Alcohol Intoxication
Family Based Prevention of Alcohol and Risky Sex for Older Teens
An online, interactive web-based program for older teens and their parents is designed to address teen alcohol use and teen relationships.
- Conditions
- Alcohol Drinking, Alcohol Intoxication, Alcohol Poison, Alcohol-Related Disorders
- Trial name
- NCT03521115
- Testing
- Smart Choices 4 Teens
- Where
- United States
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Substance Use
Developing a Digital Intervention to Prevent Risky Health Behaviors
The project will launch the development of Parents and Teens Together (PATT), a dyadic digital parent-teen prevention intervention, for families of young teens experimenting or at high risk for experimenting with substance use…
- Trial name
- PATT (NCT06538922)
- Testing
- Single Session Family Intervention
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Vermont