Clinical trials: Root Canal
Periapical Periodontitis, Root Canal Infection
The Effects of EndoActivator on Postoperative Pain and Root Canal Treatment Success
This study evaluates postoperative pain and radiographic healing of asymptomatic posterior teeth with chronic apical periodontitis following root-canal treatment performed using EndoActivator for irrigation activation.
- Trial name
- NCT06339905
- Testing
- Sonic Activation with EndoActivator, Control Needle Irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Necrotic Pulp With Symptomatic Apical Periodontitis
The Impact of Using Different Final Irrigation Modes on Postoperative Pain Following Root Canal Treatment of Non-vital Mandibular First Molar With Periapical Lesion.
The goal of this clinical trial is to learn which rinsing of root canals method works best to lower pain after a root canal in adults.
- Trial name
- NCT07623629
- Testing
- root canal treatment
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Necrotic Pulp
Effect of Moringa Oleifera Leaf Extract on Postoperative Pain and Bacterial Reduction in Mandibular Premolars
The aim of this study is to clinically compare the intensity of post-operative pain and the amount of bacterial reduction after using Moringa oleifera leaf extract solution during chemo-mechanical preparation, versus 2.5% NaOCl…
- Trial name
- NCT05348824
- Testing
- Moringa oleifera leaf, Sodium hypochlorite
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anesthesia, Local
Targeted Nerve Injection to the Knee (Nerve to Vastus Medialis): Comparing Two Adductor Canal Block Approaches
This randomized, double-blinded volunteer study compares two ways of performing the adductor canal (AC) nerve block at the mid-thigh to see which approach more reliably numbs the anteromedial knee.
- Trial name
- NCT07444827
- Testing
- Traditional adductor canal block, NVM (nerve to vastus medialis) targeted adductor canal block, Chloroprocaine Injection
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Duke University
Primary Teeth, Pulp Necroses
Treatment of Infected Pulp in Primary Teeth With a Mixture of Calcium Hydroxide and Gingerols
This study was conducted to evaluate Calcium Hydroxide mixed with Gingerols versus Metapex in treatment of primary teeth with infected necrotic pulp
- Conditions
- Primary Teeth, Pulp Necroses, Infected Pulp, Root Canal Treatment
- Trial name
- NCT05181813
- Testing
- Ginge-Cal, Metapex
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Periapical Disease
Comparing the Effect of Different Intracanal Dressing on Failed Root Canal Treated Cases on Periapical Healing
The goal of this clinical trial is to compare the effects of different intracanal medication between endodontic retreatment visits in previously failed root canal treatment patients (single root canal anteriors or premolars…
- Trial name
- NCT06342830
- Testing
- nanocurcumin gel, Curcumin Gel, Ciprofloxacin 500 mg +ibuprofen 400mg
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Vestibular Dizziness, Superior Semicircular Canal Dehiscence
Vestibular Function Outcome After Cartilage Cap Occlusion Surgery
The primary objective of this study is to measure objective, functional outcomes of patients undergoing cartilage cap occlusion surgery for a dehiscent superior semicircular canal.
- Trial name
- NCT01727544
- Testing
- cartilage cap occlusion surgery
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Dental Pain, Facial Swelling
Comparing Obturation Using Bioceramic Nano-coated Gutta-percha With Bioceramic Sealer Versus Traditional Gutta-percha With Resin Sealer for Reducing Postoperative Pain and Swelling After Root Canal Treatment in Necrotic Single-rooted Teeth.
A randomized clinical trial will compare two root canal filling approaches in necrotic single-rooted teeth. The test group will receive bioceramic mono-block obturation using bioceramic nano-coated gutta-percha with a bioceramic…
- Trial name
- NCT07600099
- Testing
- Resin sealer with conventional gutta percha., Bioceramic sealer with bioceramic gutta-percha.
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Number of Roots, Number of Root Canals
Assessment of the Variations in the Root Canal System of the Permanent Mandibular First and Second Molars Among Egyptian Population Using Cone Beam Computed Tomography
A cross-sectional study to estimate Variations in the Number of Roots and the Root Canal System of the Permanent Mandibular First and Second Molars in a Sample of Egyptian Population using cone beam computed tomography through…
- Trial name
- NCT03530865
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Operative Pain
Reduction of Post-endodontic Pain After RCT When Intracanal Cryotherapy is Used.
The goal of this research was to relate the occurrence of post-endodontic pain after single-visit RCT using Balanced Force technique and two reciprocating system when cryotherapy is used.
- Trial name
- PEP (NCT03448263)
- Testing
- Balanced Force technique, WaveOne technique, Reciproc technique
- Where
- Mexico
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Endodontic Disease, Postoperative Pain
Postoperative Pain in Endodontic Therapy
The goal of this clinical trial is to evaluate the change in postoperative pain in mandibular premolar and first molar teeth with asymptomatic apical periodontitis when using EDDY and passive ultrasonic irrigation activation…
- Trial name
- NCT06741592
- Testing
- EDDY Group, PUI Group
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Ordu University
Infant, Newborn, Diseases, Sepsis
Prevention of Perinatal Sepsis (PoPS): Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn
The purpose of this study is to evaluate whether use of the disinfectant chlorhexidine administered to the birth canal during labour and newborn at delivery can protect a woman and her baby from bacterial infections after birth.
- Conditions
- Infant, Newborn, Diseases, Sepsis, Puerperal Infection
- Trial name
- NCT00136370
- Testing
- Chlorhexidine, Birth canal wipe, sterile water external genital wipe
- Where
- South Africa
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Low-level Light Therapy, Cryotherapy
Comparison Between Low-level Laser Therapy, Intracanal Cryotherapy and Their Combination, on Post-endodontic Pain Level
Statement of the problem: Postoperative pain following endodontic treatment is a common complication that might require analgesics for pain relief.
- Trial name
- NCT04006717
- Testing
- Low Level Laser therapy, Intra canal Cryotherapy
- Where
- Egypt
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Misr International University
Postoperative Pain After Knee Arthroscopy
Effect of Pregabalin or Adductor Canal Block on Postoperative Analgesia
arthroscopically Anterior Cruciate Ligament Reconstruction (ACL) under spinal anesthesia were included in this study.
- Trial name
- NCT03530280
- Testing
- pregabalin (lyrica), adductor canal block including bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Ankara Diskapi Training and Research Hospital
Anxiety
Measurement of the Hippocampal Theta Rhythm From the Outer Ear Canal
New technologies are needed to help diagnose anxiety disorders. EVestG has facilitated the identification of numerous possible biomarkers of several psychiatric disorders.
- Trial name
- NCT03954483
- Testing
- Buspirone 10 Mg Oral Tablet, Triazolam 0.25 MG Oral Tablet
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Pain Measurement, Knee Replacement Arthroplasty
Anterior Cutaneus Nerve and Distal Adductor Canal Block With USG for Total Knee Replacement Analgesia
This prospective clinical study was approved by the institutional ethics committee on September 27, 2023, and patient enrollment started in October 2023.
- Conditions
- Pain Measurement, Knee Replacement Arthroplasty, Nerve Block
- Trial name
- NCT06201195
- Testing
- Adductor canal blockade, Distal adductor canala blockade and anterior cutaneus nerve blockade
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Diskapi Teaching and Research Hospital
Endodontically Treated Teeth, Tooth Discoloration
Color Dental Alteration Caused by Endodontic Treatment
The color change of endodontically treated teeth is a common concern in clinical practice. The objective of this study will be to evaluate, in vivo, the color change (ΔE00) caused by endodontic treatment.
- Conditions
- Endodontically Treated Teeth, Tooth Discoloration, Root Canal Infection
- Trial name
- NCT03841877
- Testing
- endodontic treatment
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Knee Arthropathy
Low vs Standard Local Anesthetics Boluses for Continuous Adductor Canal Block in Total Knee Arthroplasty
To investigate the efficacy of two different regimens of local anesthetic boluses for continuous adductor canal block under ultrasound-guidance in total knee arthroplasty at King Chulalongkorn Memorial Hospital.
- Trial name
- NCT06179628
- Testing
- Low bolus concentration and volume
- Where
- Thailand
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Total Knee Arthroplasty
Single-injection Adductor Canal Block for Total Knee Arthroplasty Under Spinal Anesthesia
This study evaluates the effect of the single-injection adductor canal block in patients receiving total knee arthroplasty under spinal anesthesia.
- Trial name
- NCT04400708
- Testing
- adductor canal block, control group
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Effects of; Cold
Role of Cryotherapy in Reduction of Post Operative Endodontic Pain Following Single Visit Root Canal Therapy
AIM : To determine the efficacy of cold saline irrigation in reduction of post operative pain following root canal therapy. METHODOLOGY : Forty patients requiring root canal treatment on permanent single rooted teeth were…
- Trial name
- NCT03044470
- Testing
- cryotherapy
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mamata Dental College