Clinical trials: Root Canal
Pain
Continuous Adductor Canal Block With a New Catheter - Primary Placement and Secondary Repositioning
This is a single center, randomized, blinded trial in healthy volunteers. The volunteers will receive bilateral placement of the new catheter corresponding to the adductor canal.
- Trial name
- NCT02657603
- Testing
- Lidocaine, LAX insertion of catheter, SAX insertion of catheter
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Kai Henrik Wiborg Lange
Blood Contamination of Root Canal During Endodontic Therapy
A New Approach for Controlling Hemostasis During Canal Treatment: a Pilot Study
Blood contamination, such as apical microleakage, of root canal during preparation can be a major problem in endodontics. The purpose of this investigation was to evaluate the hemostatic properties of sulfonic/sulfuric acid…
- Trial name
- NCT03060486
- Testing
- HYBENX®
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Dr Riccardo Pace
Postoperative Pain
The Effect of Using Different Single File Systems With Coronal Flaring Instruments on Postoperative Pain
Pain after root canal treatment is an important problem that affects the quality of life of patients. Common factors affecting the formation of pain after root canal treatment include insufficient root canal shaping, irrigation…
- Trial name
- NCT05042713
- Testing
- WaveOne Gold, One Curve, OneFlare
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Infected Pulp, Root Canal Treatment
Evaluation Of Different Pulpotomy Agents Used For Treatment Of Immature Molars
The management of permanent teeth with incomplete root development with compromised pulpal integrity presents a unique challenge.
- Trial name
- NCT05347160
- Testing
- Biodentine
- Where
- Egypt
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Symptomatic Irreversible Pulpitis, Apical Periodontitis
Postoperative Pain and Healing in Teeth Treated With GentleWave or EndoActivator
Patients with painful molars will be randomly assigned to 2 different groups: GentleWave and EndoActivator. The root canals will be completed using identical protocols except in the mode of delivery and activation of irrigation…
- Trial name
- NCT04552132
- Testing
- Multisonic vs Sonic activation of irrigants
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Chronic Apical Periodontitis, Pulp Necrosis
Clinical and Inflammatory Outcomes of Regenerative Endodontic Treatment Using Injectable Platelet-Rich Fibrin in Mature Necrotic Teeth With Chronic Apical Periodontitis.
This randomized clinical trial aims to compare regenerative endodontic treatment using injectable platelet-rich fibrin (i-PRF) with conventional root canal treatment in mature necrotic anterior teeth with chronic apical…
- Trial name
- REGEN-iPRF (NCT07913399)
- Testing
- Conventional Root Canal Treatment, Regenerative Endodontic Treatment with i-PRF, Injectable Platelet-Rich Fibrin (i-PRF)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medipol University
Endodontically Treated Teeth, Root Canal Infection
Tooth Crown Discoloration Caused by Endodontic Treatment
The color change of endodontically treated teeth is a common concern in clinical practice. The objective of this study will be to evaluate, in vivo, the color change (ΔE00) caused by endodontic treatment.
- Conditions
- Endodontically Treated Teeth, Root Canal Infection, Tooth Discoloration
- Trial name
- NCT03841370
- Testing
- endodontic treatment
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Quadriceps Function Monitored With Electromyography
Compare the Quadriceps Function of Adductor Canal Block Versus Femoral Nerve Block With Electromyography Following Total Knee Arthroplasty
Adductor canal block and femoral nerve block are the most commonly used nerve blocks for pain control after total knee arthroplasty.
- Trial name
- NCT04778774
- Testing
- Nerve block
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Root Canal Therapy
Clinical Applicability of PBSCIMMO as a Single Material in Endodontic Obturations
A randomized, interventional, prospective, unicentric clinical study, 86 patients will be submitted to endodontic treatment of necrotic teeth.
- Trial name
- PBSCIMMO (NCT03514264)
- Testing
- Gutta Percha and AHPLUS cement (group A), PBS CIMMO cement (group B)
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
Pain
Postoperative Pain of Root Canal Therapy With Three Techniques
The purpose of this prospective, randomized, double-blind study was to compare the prospective pain in asymptomatic mandibular molar teeth with necrotic pulp and periapical lesion using three different instrumentation files…
- Trial name
- NCT02442388
- Testing
- Instrumentation technique with hand file, Instrumentation technique with ProTaper, Instrumentation technique with WaveOne
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Irreversible Pulpitis, Apical Periodontitis
Ethanolic Extract of Sapindus Mukorrossi as Final Endodontic Irrigant.
The chief aim of root canal treatment is to reduce the microbial content and prevent further recontamination in the canal. Properly cleaned, shaped and obturated teeth will be having fewer chances of treatment failure.
- Conditions
- Irreversible Pulpitis, Apical Periodontitis, Root Canal Infection
- Trial name
- NCT05038059
- Testing
- ethanolic extract of sapindus mukorossi, ethylene diamine tetra acetic acid
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Arrhythmias, Cardiac
Risk Stratifications for Patients With Palpitations
the aim of the study is to early diagnose and early proper mangment of those patients who have palpitations specially of cardiac origin
- Trial name
- NCT06103305
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Assiut University
Muscle Strength, Healthy Volunteers
Adductor-Canal-Blockade Versus the Femoral Nerve Block Effect on Muscle Strength and Mobilization in Healthy Volunteers
The aim of this study is to investigate the efficacy of the Adductor-Canal-Blockade versus the femoral nerve block versus placebo on muscle strength in healthy volunteers.
- Trial name
- NCT01449097
- Testing
- Adductor-Canal-Blockade, The femoral nerve block
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Endodontically Treated Teeth
The Effect of Root-canal Medicaments on Post-operative Pain in Re-treatment Cases
This randomized clinical trial compares the effects of intracanal medicaments on the incidence of postoperative pain and flare-up in asymptomatic retreatment cases.
- Trial name
- NCT05052814
- Testing
- root canal medicament-calcium hydroxide, root canal medicament-chlorhexidine gel, root canal medicament-calcuim hyroxide &chlorhexidine ge
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Root Canal Therapy
Apical Size and Root Canal Treatment Success Trial (AS-RCT Trial)
This study is looking into two different ways to perform a root canal treatment. The study will look at differences and compare the two different treatment options over a 2-year period.More specifically, this study evaluates a…
- Trial name
- AS-RCT (NCT03053037)
- Testing
- final apical size instrumentation
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Washington
Arthroplasty Replacement, Knee, Anesthesia Conduction
Migration Rate for Continuous Adductor Canal Block Catheters After Primary Total Knee Arthroplasty Surgery: a Comparison Between Two Insertion Techniques
Continuous adductor canal block (CACB) is becoming increasingly popular for providing postoperative analgesia following knee arthroplasties.
- Trial name
- ISAFExOOPS (NCT07681622)
- Testing
- ISAFE technique for adductor canal catheter insertion, OOPS technique
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Apical Periodontitis, Periapical Radiolucency
Comparative Evaluation of Clinical and Radiographic Treatment Outcomes of Garlic Gel and Calcium Hydroxide as an Intracanal Medicament in Nonsurgical Root Canal Treatment of Permanent Teeth.
Researchers want to check how well garlic works inside permanent teeth as a medicament during root canal treatments. Garlic has shown to possess many helpful properties, like reducing inflammation, helping wounds heal, and…
- Trial name
- NCT07289971
- Testing
- Allium Sativum as an intracanal medicament
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Health Sciences Lahore
Postoperative Pain, Nausea and Vomiting, Postoperative
Efficacy of Non-weight Based, Low Dose Dex-Dex Adjuncts in Prolonging Peripheral Nerve Blocks
The goal of this clinical study is to improve upon the standard practice of utilizing nerve blocks to enhance the satisfaction of patients undergoing shoulder, or foot and ankle surgery regarding their quality of pain control…
- Conditions
- Postoperative Pain, Nausea and Vomiting, Postoperative, Dizziness, Constipation
- Trial name
- Dex-Dex PNB (NCT07099222)
- Testing
- Low, non-weight based dose of Dexamethasone and Dexmedetomidine in peripheral nerve blocks, Ropivacaine with low, non weight based Dexamethasone additive
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Root Canal Infection
Bacterial Reduction and Post Operative Endodontic-pain Using Different Kinematics
This study was conducted to compare the antibacterial effect and degree of postoperative pain of single rotary and reciprocating file systems during endodontic therapy
- Trial name
- NCT04990115
- Testing
- root canal shaping
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
This Study Compares the Effects of Two Working Length Methods on Postoperative Pain in Single-rooted, Single-canal Teeth During Root Canal Retreatment
Evaluation of Postoperative Pain After Endodontic Retreatment Using Different Working Length Determination Methods: A Randomized Clinical Trial
The aim of this study is to compare the effects of two different working length determination methods on the incidence of postoperative pain in single-rooted, single-canal teeth undergoing root canal retreatment (RCR).
- Trial name
- NCT06732063
- Testing
- endodontic retreatment
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- öznur dişli