Clinical trials: Root Canal Therapy
Pulpitis, Periapical Lesions
Success of Endodontic Treatment With Different Obturation Techniques and Sealer Cements
The present study aims to compare the radiographic success of endodontic treatment using Orstavik's criteria between two sealers: AH Plus (Dentsply DeTrey, Konstanz, Germany) and Neosealer Flo (Avalon Biomed, Bradenton, Florida…
- Conditions
- Pulpitis, Periapical Lesions, Periapical Periodontitis, Periapical Pathology
- Trial name
- NCT07019298
- Testing
- AH Plus (Dentsply Sirona, Charlotte, NC, USA), NeoSealer Flo, Continuous Wave Condensation
- Where
- Spain
- Volunteers
- 270 people
- Sponsor
- University of Siena
Asymptomatic Irreversible Pulpitis
Effect of Apical Third Enlargement to Different Taper and Master Apical Preparation Size on Periapical Healing and Postoperative Pain After Primary Single Sitting Non Surgical Root Canal Treatment
To Determine Effect Of Apical Third enlargement To Different Taper And Master Apical Preparation Size On Periapical Healing And Postoperative Pain After Primary Single Sitting Non Surgical Root Canal Treatment : A Randomized…
- Trial name
- NCT07166679
- Testing
- root canal treatment with 2% taper, root canal treatment with 4% taper, root canal treatment with 6 %taper
- Where
- India
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Necrotic Pulp, Apical Periodontitis
Regenerative Endodontic Treatment of Mature Necrotic Teeth With Apical Periodontitis
The aim of this prospective, randomized, controlled double-blind study is to evaluate the effectiveness of biodentine compared with MTA used as pulp space barrier on discoloration of teeth after regenerative based non-obturation…
- Trial name
- NCT04018456
- Testing
- Biodentine, White MTA
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Root Canal Therapy, Root Canal Retreatment
Factors Affecting Success and Survival Rates in Root Canal Retreatment
The aim of this study is to evaluate the effects of pre-treatment and procedural factors on survival and success rates in teeth that underwent non-surgical root canal retreatment at Trakya University, Faculty of Dentistry between…
- Trial name
- NCT07005492
- Testing
- radiological and clinical examination
- Where
- Turkey (Türkiye)
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- Trakya University
Root Canal Treatment
Post-Endodontic Pain According to Menstrual Cycle Phases
This study aimed to evaluate whether the phase of the menstrual cycle affects pain after root canal treatment. A total of 99 patients (72 females and 27 males) who needed root canal treatment in lower molar teeth were included.
- Trial name
- PEP-MC (NCT07291518)
- Testing
- root canal treathment
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Ahter Sanal Cikman
Root Canal Treatment, Endodontic Disease
Endodontic Root-canal Treatments Evaluated After Long-term Time
The aim of the study was to evaluate the root canal treatments performed from 1989 to 1995. Type of complication, success, new endodontic diseases and number of success were reported.
- Trial name
- ENDOBO20 (NCT03215225)
- Testing
- Root canal orthograde treatment
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Postoperative Pain After Endodontic Treatment, Direct Pulp Capping
Diagnostic Validity of a Quantitative Pulp Pain Scoring System and Its Association With Postoperative Clinical Outcomes
Pulpal diseases are among the most common reasons for endodontic treatment in dental practice. The dental pulp plays a critical role in maintaining tooth vitality, and its pathological changes directly affect pain perception and…
- Conditions
- Postoperative Pain After Endodontic Treatment, Direct Pulp Capping, Vital Pulp Therapy
- Trial name
- NCT07349511
- Testing
- Root canal treatment procedure based on the total score obtained from the Youden symptom scoring system, Vital pulp therapy procedure based on the total score obtained from the Youden symptom scoring system
- Where
- Turkey (Türkiye)
- Volunteers
- 143 people
- Sponsor
- Recep Tayyip Erdogan University
Oxidative Stress, Chronic Apical Periodontitis
Effect of Different Root Canal Sealers on Oxidative Stress Markers
The goal of this clinical trial is to primary purpose investigate and compare oxidative stress markers in patients with chronic apical periodontitis treated with different root canal paste in a single session.
- Trial name
- NCT07059481
- Testing
- Root Canal Treatment and Sample Collection, PAI Score Comparasion
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- bengi gülgü
Apical Periodontitis
Apical Patency, Periapical Lesion Volume, and Postoperative Pain After Root Canal Treatment
This prospective clinical study evaluated whether maintaining apical patency during single-visit root canal treatment influences postoperative pain in adults with single-rooted maxillary anterior teeth and chronic apical…
- Trial name
- NCT07782515
- Testing
- Apical Patency During Root Canal Treatment, Root Canal Treatment Without Apical Patency
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people
- Sponsor
- Recep Tayyip Erdogan University
Apical Periodontitis
Effect of Apical Patency on Success of Root Canal Treatment in Non Vital Teeth
Maintaining Apical patency during root canal treatment is a widely followed methodology in modern endodontic treatment protocols.
- Trial name
- NCT03454815
- Testing
- Apical patency
- Volunteers
- 65 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Apical Extrusion During Root Canal Treatment
Measuring Apical Debris Extrusion With a Novel Laboratory Technique
Endodontic treatment occupies a critical role in dentistry, serving to prolong the longevity of teeth within the oral cavity and prevent early tooth loss.
- Trial name
- NCT07341451
- Testing
- ProTaper Gold Rotary File System, ProTaper Next Rotary File System
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Fatma Selenay Ucas Yildiz
Pain, Postoperative
Comparison of Post-operative Pain Frequency
The objective of this study is: To compare the post-operative pain frequency after single visit root canal versus multiple visit root canal treatment in patients with non-vital teeth Post-operative pain is less frequent after…
- Trial name
- NCT04944589
- Testing
- ROOT CANAL TREATMENT
- Where
- Pakistan
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Fatima Memorial Hospital
Acute Pulpitis
Evaluation of the Effect of Root Canal Preparation by TF and M-Pro on Post-Operative Pain After Single Visit Endodontic Treatment
A study to comparatively evaluate the post operative pain between root canal preparation by reciprocating file (TF) and full rotation file (M-Pro) in patients with single rooted teeth with acute irreversible pulpits.
- Trial name
- NCT03412318
- Testing
- Twisted file, Mpro
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post-operative Pain
Reduction of Post-endodontic Pain After 3 Irrigation Regime
The goal of this research was to relate the occurrence of post-endodontic pain after single-visit RCT using there irrigating regime.
- Trial name
- RPEP (NCT03559140)
- Testing
- Applied saline solution at 2.5 oC (Cryotherapy group), Applied saline solution at 8oC (Cryotherapy ), Applied saline solution at room temperature (No cryotherapy)
- Where
- Mexico
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Root Canal Obturation, Root Canal Filling
Outcome of SBO With Calcium Silicate Sealer vs WVC With Resin Based Sealer
A single blinded randomized controlled trial. 212 subjects (teeth), 106 in each of the 2 groups will be recruited from the patients referred to Kuwait Board of Endodontics for primary root canal treatment.
- Conditions
- Root Canal Obturation, Root Canal Filling, Sealer-based Obturation, Randomized Clinical Trial
- Trial name
- NCT04753138
- Testing
- TotalFill Bioceramic Sealer, AH+ Sealer
- Where
- Kuwait
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Kuwait Institute for Medical Specialization
Ultrasound Therapy; Complications
Ultrasound-Guided Versus Conventional Injection for Caudal Block
Caudal epidural block has been widely used, especially in pediatric surgery, to provide intraoperative and postoperative analgesia by affecting the region between T10 and S5 dermatomes in surgeries below the umbilical level.
- Trial name
- NCT03337191
- Testing
- Levobupivacaine, Morphine Sulfate, Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Ataturk University
Periapical Diseases, Postoperative Dental Pain
Postoperative Pain in Photodynamic Therapy Using Curcumin As a Photosensitizer
In endodontics, various irrigation solutions are used to achieve antibacterial efficacy within the root canal. The antibacterial effect of curcumin-containing root canal solutions, when combined with photodynamic therapy, has…
- Conditions
- Periapical Diseases, Postoperative Dental Pain, Irrigation Solution, Photodynamic Therapy (PDT)
- Trial name
- NCT06752655
- Testing
- Curcumin with photodynamic thearpy, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Effect of Drug
Comparing Trypsin-Chymotrypsin and Naproxen Sodium for Post-endodontic Treatment Pain
This study aims to compare the pain reduction efficacy of Trypsin-Chymotrypsin and Naproxen sodium after root canal treatment in patients with symptomatic irreversible pulpitis.
- Trial name
- NCT06562816
- Testing
- Trypsin-Chymotrypsin, Naproxen Sodium 550mg
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Apical Periodontitis
N-acetylcysteine for Root Canal Treatment of Necrotic Teeth With Apical Periodontitis
A randomized controlled trial comparing the postoperative pain intensity, periapical biomarkers level, and periapical healing in patients with necrotic mature teeth and apical periodontitis treated with N-acetylcysteine (NAC), as…
- Trial name
- NAC (NCT07262554)
- Testing
- Calcium hydroxide (Ca(OH)₂), N-Acetylcysteine (NAC)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Root Canal Therapy
Postoperative Pain Assessment After Using Different Kinematics
The aim of this study is to evaluate postoperative pain after endodontic instrumentation using rotation, reciprocation and adaptive motion.
- Trial name
- NCT04277520
- Testing
- Root canal therapy
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University