Clinical trials: Root Caries
Dental Restoration Failure
Clinical Evaluation of Nano Hydroxyapatite Reinforced Glass Ionomer in Treatment of Root Caries in Geriatric Patients
In geriatric patients, will the clinical performance of nano hydroxyapatite reinforced glass ionomer be better than conventional glass ionomer cement in treatment of root caries lesions over one year follow up?
- Trial name
- NCT04701320
- Testing
- Conventional glass ionomer, Nano hydroxyapatite reinforced glass ionomer
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cervical Caries
Clinical Evaluation of Self-Adhesive Bulk-Fill Composite Versus Conventional Nano-hybrid Composite in Cervical Cavities
The aim of this randomized clinical trial is to compare the six months clinical performance of the self-adhesive bulk-fill composite with the conventional nano-hybrid composite in the cervical lesions of teeth in the esthetic…
- Trial name
- NCT06394440
- Testing
- Self-Adhesive Bulkfill Composite (Surefil One)
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Misr International University
Dental Caries
Preventing and Arresting Dental Root Surface Caries in Community-dwelling Older Adults
This study is a randomized clinical trial lasting for 30 months. A total of 300 subjects will be recruited from social centres for elders located in different districts in Hong Kong.
- Trial name
- NCT02360124
- Testing
- silver diammine fluoride, saturated potassium iodide solution
- Where
- China
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Pulpitis - Irreversible
Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
This study is a randomised controlled trial for complete pulpotomy as an alternative to root canal treatment for teeth with clinical diagnosis of symptomatic irreversible pulpitis (i.e.
- Trial name
- NCT05964933
- Testing
- Complete Pulpotomy, Pulpectomy and Root Canal Treatment
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Caries,Dental, Apical Periodontitis
Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - Endodontics
The primary goal of the study is to compare the success rates of pulpal anesthesia (defined as ability to complete the intended dental procedure without the need for rescue anesthesia) between Kovanaze nasal mist and Articaine…
- Trial name
- NCT04105985
- Testing
- Kovanaze Nasal Spray, Articaine Injection
- Sponsor
- Virginia Commonwealth University
Root Caries
Non-invasive Treatment of Root Caries in Older Adults
This study aims to test the effectiveness in reducing or arresting root caries lesion in community-dwelling elderly subjects by using high fluoridated toothpaste.
- Trial name
- MIT-RCTalca (NCT02647203)
- Testing
- Self-administered fluoridated dentifrices
- Where
- Chile
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- University of Talca
Clinical Performance
Performance Of Cervical Restorations Using Nitric Acid and Mineral Enriched Adhesive Versus Phosphoric Acid and Universal Adhesive
To evaluate the clinical performance of multifunction Nitric acid etch, mineral enriched adhesive and flowable resin composite liner versus the universal adhesive in etch and rinse mode and regular flowable liner in cervical…
- Trial name
- NCT05928533
- Testing
- clean and boost enamel cleanser of vista apex , RE GEN universal adhesive from vista apex , RE GEN Bio active flowable composite form vista apex
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Cairo University
Apical Periodontitis, Pulp Disease, Dental
In Vivo-Ex Vivo Evaluation of the Root ZX3 for Working-Length Determination
This study evaluates the accuracy and repeatability of the Root ZX3 electronic apex locator for determining root canal working length in single-rooted permanent teeth requiring extraction.
- Trial name
- NCT07689838
- Testing
- Root ZX3 Electronic Apex Locator
- Where
- Saudi Arabia
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Cervical Caries
Clinical Performance of Short Fiber Reinforced Resin Modified Glass Ionomer Restorations in Cervical Carious Teeth (1y Randomized Clinical Trial)
This research proposal is introduced to clinically test short fiber reinforced glass ionomer material from GC Europe due to gap of knowledge present in this area.
- Trial name
- NCT06185881
- Testing
- restoration of cervical carious teeth
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Root Caries
Silver Diamine Fluoride Treatment of Active Root Caries Lesions in Older Adults: A Case Series
The authors conducted a case series to determine the outcomes of treatment of root surface caries lesions when the teeth were treated topically with 38% silver diamine fluoride.
- Trial name
- NCT04370080
- Testing
- Silver Diamine Fluoride 38%
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Roseman University of Health Sciences
Root Caries
Evaluation of Corrective Surgery Versus Dental Implants in Compromised Upper Molars
This study seeks to assess the clinical, radiographic, and patient-reported outcomes of root amputation versus implant over a 12 months period, generating robust evidence to guide clinical decision-making and enhance patient care.
- Trial name
- NCT07608497
- Testing
- root amputation
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Decayed Teeth
Laser Activation in Reducing Pain During and After Root Canal Treatment for Painful Lower Molar Teeth.
Effectiveness of lasers in reducing pain during and after root canal treatment for mandibular molar teeth affected with acute irreversible pulpitis.
- Trial name
- NCT04735120
- Testing
- iLASE DIODE LASERS
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CSI College of Dental Sciences and Research, Madurai
Cervical Caries
Nobio Antimicrobial Particles Effect in a Split Mouth Model
The study purpose is to evaluate the antimicrobial effect of Nobio particles incorporated within Novidia Dental Bonding and Flowable Composite versus standard of care within a split mouth model.The study population will include…
- Trial name
- NCT03501784
- Testing
- Nobio particles incorporated within Novidia Dental Bonding, Filtek bond and flow composite
- Where
- Israel
- Volunteers
- 35 people
- Sponsor
- Nobio Ltd.
Root Caries, Cognitive Impairment
High Fluoride and Root Caries in Older Adults (NIT-RCL-UTALCA)
This project aims to provide an effective solution for root caries lesions (RCLs), specifically in older persons with cognitive impairment through a non-invasive therapy with Silver Diamine Fluoride (SDF).
- Conditions
- Root Caries, Cognitive Impairment, Fluor
- Trial name
- SDF-RCL (NCT06749275)
- Testing
- 5,000 ppm fluoride toothpaste, 22,600 ppm fluoride varnish, 38% SDF
- Where
- Chile
- Volunteers
- 179 people
- Sponsor
- University of Talca
Dental Caries, Cervical Caries
Clinical Performance of High Viscous Glass Ionomer Cervical Restorations With Silver-Modified Atraumatic Restorative Technique (SMART) Versus Conventional Treatment in Elderly Cancer Patients. (A 12-month Randomized Clinical Trial)
This study will evaluate the clinical performance of glass ionomer cervical restorations placed using the Silver-Modified Atraumatic Restorative Technique (SMART) compared with conventional restorative treatment in elderly cancer…
- Trial name
- NCT07803757
- Testing
- Silver Diamine Fluoride (SDF, 38%), Conventional Tooth Preparation, High-Viscosity Glass Ionomer Cement
- Volunteers
- 30 people
- Sponsor
- Cairo University
Root Caries
36-Month Clinical Performance of Different Restorative Materials in the Treatment of Root Caries Lesions
This is a split-mouth, randomized clinical study that evaluating the 36-month performance of different restorative materials in the treatment of root caries lesions.
- Trial name
- NCT03722758
- Testing
- Spectrum TPH3, Riva LC
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Root Caries
Prevention and Arrest of Root Caries Lesions with High Fluoride Concentration Mouthwash Versus Normal Fluoride Concentration Mouthwash in Elderly Patients
The study evaluats the effectiveness of regular fluoride 220 ppm F with erythritol and high fluoride 500 ppm F with erythritol mouthwashes against a placebo (regular fluoride 220 ppm F mouthwash) in the prevention of new root…
- Trial name
- NCT06723054
- Testing
- regular fluoride 220 ppm F mouthwash without erythritol, regular fluoride 220 ppm F mouthwash with erythritol, high fluoride 500 ppm F mouthwash with erythritol
- Where
- Switzerland
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Murali Srinivasan, Dr. med. dent., BDS, MDS, MBA, MAS
Caries, Cervical
Evaluation of Low-shrinkage Giomer Versus Resin-Modified Glass Ionomer in Cervical Caries Lesions: A Clinical Trial
Management of cervical lesions presents serious problems with any restorative material. The two most common reasons for restoration failure are secondary caries at the tooth-restoration interface and loss of retention.
- Trial name
- NCT05930548
- Testing
- Low Shrinkage Giomer
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Root Resorption, Distal Caries
Frequency of External Root Resorption in Mandibular Second Molars Associated With Mandibular Impacted Third Molars Using CBCT
The prevalence of external root resorption and distal caries in mandibular second molars associated with impacted mandibular third molars will be detected in addition to the association of the risk factors.
- Trial name
- NCT03981367
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Cairo University
Active Root Caries, Over Sixty-five Years of Age
Treatment of Root Caries in an Older Irish Population.
This study will involve filling teeth which have decay on their roots with three different filling materials. Patients will attend Cork University Dental School and hospital for a clinical examination and to complete a…
- Conditions
- Active Root Caries, Over Sixty-five Years of Age, >=Two Carious Root Surfaces Per Patient
- Trial name
- NCT01866059
- Testing
- Calcium silicate cement, Glass Ionomer Cement, Resin Modified Glass Ionomer Cement
- Where
- Ireland
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University College Cork