Clinical trials: Root Planing
Gingival Recession, Root Planing
Gingival Recession Treatment Using Two Different Surgical Techniques
Coronally the advanced flap is considered a predictable treatment of gingival recession but in certain situations, it needs a filler like subperiosteal connective tissue graft (CTG) which is considered as the gold standard…
- Trial name
- NCT04966208
- Testing
- xenogeneic collagen matrix
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Assiut University
Periodontal Index, Pain
Efficacy of Zinc L-Carnosine Mouth Rinse
A clinical trial to assess the effect of a Zinc-L-Carnosine-based mouth rinse on periodontal tissues and pain after scaling and root planing
- Trial name
- NCT04430998
- Testing
- Zinc L-Carnosine, Chlorhexidine, Water
- Where
- Italy
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Milan
Periodontitis
Clinical and Microbiological Efficacy of Chloramine and Hyaluronic Acid Gels in Non-surgical Periodontitis Treatment
The aim of the study is to investigate clinical and microbiological effects of subgingival application of chloramine (Perisolv) and hyaluronic acid (Hyadent BG) gels as adjuncts to scaling and root planing in non-surgical…
- Trial name
- NCT04662216
- Testing
- Scaling and root planing, Scaling and root planing + "Perisolv" +"Hyadent BG" gels
- Where
- Lithuania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Chronic Periodontitis
Effect of Scaling and Root Planing Along With Topical Application of Commercially Available Curcuma Longa Gel on Superoxide Dismutase and Malondialdehyde Levels in Saliva of Chronic Periodontitis Patients
Periodontitis is initiated by microbial biofilm but its progression is mediated by an abnormal host response to biofilm microorganisms.
- Trial name
- NCT02442453
- Testing
- Topical application of curenext gel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Periodontitis, Diabetes Mellitus
Efficacy of Hydrogen Peroxide Gel on Periodontitis With Diabetes
Periodontitis is a chronic infectious disease characterized by loss of tooth supporting periodontal structures and alveolar bone. In the U.S. and worldwide, periodontitis is the major cause of tooth loss in adults.
- Trial name
- Peroxide gel (NCT05669560)
- Testing
- PerioProtect ™= plastic tray +1.7% hydrogen peroxide
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Oklahoma
Chronic Periodontitis
Influence of Mouth Breathing on Periodontal Healing
Studies reveal association between dry conditions and decreased healing in wounds or any treatment. From these studies, it can be hypothesized that healing in mouth breathers after scaling and root planing in terms of bleeding on…
- Trial name
- NCT03169322
- Testing
- SRP
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontitis
Clarithromycin is an Adjunct to Scaling and Root Planing
The present study was done to evaluate the effect of clarithromycin as an adjunct to scaling and root planning at baseline, three months and six months intervals .
- Trial name
- CASRCMI (NCT02359721)
- Testing
- tablet clarithromycin 500 mg (Clarino-500) orally
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Chronic Periodontitis, Probiotics
Adjunctive Probiotics in Chronic Periodontitis
This study will assess clinical and microbiological efficacy of probiotics and antibiotics in patients of chronic periodontitis as an adjunctive to scaling and root planing (SRP) in reducing bacterial count and in improving…
- Trial name
- NCT03499184
- Testing
- P Flor locally delivered, P Flor systemically administered, Amoxil 500 mg Oral Capsule
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ziauddin Hospital
Periodontal Healing, Periodontitis
The Effectiveness of Root Planing and Injectable Platelet-Rich Fibrin in Smoking Patients With Periodontitis
Periodontitis is a chronic, multifactorial inflammatory disease characterized by the progressive destruction of the tissues supporting the teeth, associated with dysbiotic plaque biofilms.
- Conditions
- Periodontal Healing, Periodontitis, i-PRF
- Trial name
- NCT07049549
- Testing
- Injectable PRF, Plasebo (Sterile Saline)
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Chronic Periodontitis
Effectiveness of Locally Delivered Morus Alba Gel on Moderate Periodontitis
Background: Periodontitis is a chronic inflammatory disease of tooth and supporting tissues with clinical signs of bone and connective tissue loss and is mediated by a combination of periodontal pathogens and host defense…
- Trial name
- NCT03475394
- Testing
- Chlorhexidine gel, Morus alba gel
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- KLE VK Institute of Dental Sciences
Chronic Periodontitis
Effect Of A Locally Delivered Probiotic Sacchraomyces Boulardii In The Management Of Chronic Periodontitis
This study was carried out in the Department of Periodontology and source of patient was be from the outpatient section of Tatyasaheb Kore Dental College \& Research Centre, New Pargaon.
- Trial name
- NCT03516370
- Testing
- Saccharomyces Boulardii 250 MG
- Where
- India
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
SRP, Minocycline HCl Microspheres
Scaling and Root Planing (SRP) With and Without Minocycline HCl Microspheres, 1 mg
The primary goal of this study is to investigate the qualitative and quantitative effects of scaling and root planing (SRP) with and without minocycline HCL microspheres, 1 mg on periodontal pathogens and overall bacterial load.
- Conditions
- SRP, Minocycline HCl Microspheres, Biomarkers
- Trial name
- NCT03762915
- Testing
- minocycline HCl microspheres
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Heart Failure, Periodontitis
Periodontitis Treatment and Heart Failure
Heart failure (HF) is a rapidly growing public health issue affecting more than 40 million individuals globally; while gum disease with bone loss affects 50% of people in general.
- Trial name
- NCT07036289
- Testing
- Mechanical Treatment
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Taubate
Chronic Periodontitis
Role of Leukotriene Receptor Antagonists in Treatment of Chronic Periodontitis
The adjunctive use of Leukotriene Receptor Antagonist (Montelukast) along with scaling and root planing in patients with chronic periodontitis leads to host inflammatory response modulation and decrease in serum C reactive…
- Trial name
- NCT02014532
- Testing
- Montelukast
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Periodontal Diseases, Gingival Diseases
Novel Dental Gel as an Adjunct to Scaling and Root Planing
This study will evaluate the use of Livionex Dental Gel (LDG) as a home care product in reducing probing pocket depth (PD) beyond the effect achieved by the current standard of care with SRP in periodontitis patients.
- Conditions
- Periodontal Diseases, Gingival Diseases, Gingival Pocket, Gum Bleed
- Trial name
- NCT05384132
- Testing
- SRP + Livfresh Dental Gel, SRP + standard flouride dentifrice
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Periodontal Pocket
Evaluation of 2%Bromelain Gel With 0.2%CHX Gel as Subgingival LDD Following SRP in Stage II/III and Grade B Periodontitis -A RCT
The current study is a prospective randomised study Evaluation of 2%Bromelain Gel With 0.2%Chlorhexidine Gel as Subgingival Local Drug Delivery Following Scaling and Root Planing in Stage II/III and Grade B Periodontitis
- Trial name
- NCT06505759
- Testing
- Bromelain gel, chlorhexidine gel, SRP
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Periodontitis
Treatment Of Shallow Periodontal Pockets Using PRF As an Adjunct To Scaling And Root Planing In Periodontitis Patients
Platelet rich fibrin (PRF) has been widely used in regenerative dentistry since it provides plenty amount of growth factors that enhance wound healing and tissue regeneration.
- Trial name
- NCT05890157
- Testing
- PRF
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Chronic Periodontitis
Efficacy and Safety of a Commercially Available Injectable Hyaluronic Acid Dental Filler for Periodontal Pockets
This is a controlled, randomized, single-blinded, multicenter, prospective clinical study. In addition to the standard periodontal treatment procedure on all teeth that need to be treated, the 4 teeth with the deepest pockets…
- Trial name
- NCT02391974
- Testing
- PERIOSYAL FILL
- Where
- 3 sites in Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Periodontitis
Single Session Of Antimicrobial Photodynamic Therapy Using Indocyanine Green
In recent years, there has been a growing interest in the use of dental lasers for treatment of periodontal diseases. Commercially available photodynamic therapy for periodontal diseases utilizes methylene blue as a…
- Trial name
- NCT02043340
- Testing
- indocyanine green, LASER, Scaling and Root Planing
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences
Periodontitis
Dietary Supplements and Periodontal Wound Healing
Patient with periodontal disease undergoing full mouth disinfection will be given dietary supplements or placebo and reevaluated after 3 months.
- Trial name
- NCT02315222
- Testing
- Regenium, Full Mouth Disinfection
- Where
- 3 sites in Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Milan