Clinical trials: Ropivacaine
Inguinal Hernia
Antalgic Efficacy of CycloMesh™ Soaked in Ropivacaine Hydrochloride in Uncomplicated Inguinal Hernia.
CycloMesh is a polyester visceral implant functionalized by drug delivery systems directly on its surface, targeting a unique intervention, a slow anesthetic release and an in situ activity.
- Trial name
- HENRI (NCT04033055)
- Testing
- Inguinal hernia repair with CycloMesh™ soaked in ropivacaine hydrochloride 10mg/mL, Inguinal hernia repair with CycloMesh™ soaked in saline solution NaCl 9°/°°
- Where
- France
- Volunteers
- 304 people
- Sponsor
- Quanta Medical
Pain, Postoperative
Ropivacaine 0.2% Pre-Filled Dispenser for the Treatment of Postsurgical Pain in Patients Undergoing Cesarean Delivery
This study evaluates a Ropivacaine 0.2% Pre-Filled Dispenser in the treatment of post-surgical pain in patients undergoing Cesarean delivery. Half of the patients will receive Ropivicaine and half will receive placebo.
- Trial name
- NCT02959476
- Testing
- Ropivacaine
- Where
- 11 sites in United States
- Volunteers
- 132 people
- Sponsor
- BioQ Pharma, Inc.
Healthy, Nerve Block
Phase I Study of Ropivacaine, Clonidine, and Betamethasone Combination for Sciatic Nerve Block in the Popliteal Region
This is a national, single-center, dose-escalation Phase I study to investigate the safety, pharmacokinetics, and efficacy of a combination containing Ropivacaine, Clonidine, and Betamethasone (Ropiclobet) in healty volunteers.
- Trial name
- RopiCloBet (NCT06781632)
- Testing
- ropivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- PHARMAFINA
Axillary Nerve Block
Chloroprocaine 2% vs Ropivacaine 0.75% in Ultrasound-guided Axillary Nerve Block
The Study evaluate the non-inferiority of Test product (Chloroprocaine 2%) versus Reference product (Ropivacaine 0.75%) in terms of proportion of subjects with a successful block for distal upper limb surgeries Successful block…
- Trial name
- NCT02385097
- Testing
- Chloroprocaine HCl 2%, Ropivacaine 0.75%
- Where
- Switzerland
- Volunteers
- 211 people
- Sponsor
- Sintetica SA
Unplanned Caesarean Section
Chloroprocaine 3% - Epidural Anesthesia in Unplanned Caesarean Section
The study evaluate the quality of epidural anaesthesia and the safety of Chloroprocaine HCl 3% compared with Ropivacaine HCl 0.75% in patients with an epidural catheter in situ undergoing unplanned Caesarean section.
- Trial name
- NCT02919072
- Testing
- Chloroprocaine, Ropivacaine
- Where
- Belgium
- Volunteers
- 16 people
- Sponsor
- Sintetica SA
Hip Fractures, Intertrochanteric Fractures
EXPAREL Facia Iliaca Compartment Block for Intertrochanteric Hip Fracture
This study evaluates the effect of EXPAREL on total opioid consumption through 72 hours following fascia iliaca compartment block (FICB) in subjects undergoing repair of intertrochanteric hip fracture.
- Trial name
- RESTORE (NCT03955458)
- Testing
- EXPAREL, Ropivacaine, Bupivacaine Hydrochloride
- Where
- United States
- Sponsor
- Pacira Pharmaceuticals, Inc
Pain
A Safety and Effectiveness Pilot Study of PRF-108 and PRF-110 in Healthy Volunteers
This is a clinical study testing PRF-108 and PRF-110 (a new extended release 4% gel formulations of ropivacaine) in an experimentally induced pain model in healthy volunteers.
- Trial name
- NCT00883194
- Testing
- PRF-108, Ropivacaine, PRF-110
- Where
- Israel
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- PainReform LTD
Anesthesia,Spinal
Ropivacaine Versus Bupivacaine for Spinal Anaesthesia in Patients Undergoing Unilateral Lower Limb Surgery
The purpose of this study is to compare the efficacy, duration of motor block until return to normal function in the non-operated leg after the start of injection, of ropivacaine 5 mg/ml and bupivacaine 5 mg/ml when used for…
- Trial name
- NCT00358280
- Testing
- Ropivacaine, Bupivacaine
- Where
- 5 sites in China
- Volunteers
- 220 people
- Sponsor
- AstraZeneca
Nerve Block, Upper Extremity Surgery
Ropiclobet for Regional Anesthesia and Post-Operative Pain Control in Upper Extremity Surgery
This is a national, single-center, single-arm, open-label Phase II clinical trial designed to evaluate the efficacy and safety of Ropiclobet, a fixed-dose injectable solution containing Ropivacaine HCl, Betamethasone Sodium…
- Trial name
- NCT07131657
- Testing
- Ropivacaine + Clonidine + Betamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- PHARMAFINA