Clinical trials: Rosacea, Erythematotelangiectatic
Rosacea
Efficacy of IPL, an Anti-redness Dermocosmetic, and Their Combination in the Treatment of Rosacea
This study compares three approaches to treating persistent facial redness in adults with erythematotelangiectatic rosacea: intense pulsed light (IPL) treatment alone, a professional anti-redness dermocosmetic skincare regimen…
- Trial name
- NCT07729540
- Testing
- Intense Pulsed Light (IPL) - Lumecca, Rosacure anti-redness dermocosmetic regimen
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Silesia
Rosacea, Erythematotelangiectatic, Rosacea Subtype 1 (Erythematotelangiectatic)
Dermocosmetic Treatment for Facial Redness in Rosacea With or Without Laser Therapy
The aim of this clinical study is to evaluate the effectiveness and safety of a dermocosmetic product in reducing facial redness and visible blood vessels associated with erythematotelangiectatic rosacea.
- Trial name
- NCT07521462
- Testing
- Dermocosmetic tested product, Vascular laser treatment
- Where
- France
- Volunteers
- 50 people
- Sponsor
- ISISPHARMA
Erythematotelangiectatic Rosacea
Combination Therapy for the Treatment of Rosacea
The purpose of this study is to determine the efficacy of calcium dobesilate in combination with pulsed dye laser for the treatment of rosacea.
- Trial name
- NCT00945373
- Testing
- calcium dobesilate, pulsed dye laser
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Ellen Marmur
Rosacea, Erythematotelangiectatic
Metronidazole SC Penetrance With Moisturizers
Topical metronidazole is a widely used first line treatment for erythemotelangiectatic and inflammatory rosacea. Commonly, a moisturizer is also used to restore the skin barrier and reduce inflammation.
- Trial name
- NCT06434519
- Testing
- Metronidazole cream, Cetaphil moisturizer, CeraVe moisturizer
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Duke University
Rosacea
Atralin Gel for the Treatment of Rosacea
Erythematotelangiectatic rosacea is a type of rosacea that causes a red face often with frequent flushing, topical sensitivity and prominent blood vessels.
- Trial name
- NCT01125930
- Testing
- vehicle gel, Atralin gel
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Lisa E. Maier
Rosacea, Erythematotelangiectatic
Long Pulse 1064 nm Nd:YAG Laser in the Treatment of Erythematotelangiectatic Rosacea and Other Erythematous Telangiectatic Facial Conditions
The goal of this clinical study is to assess the effectiveness of Nd:YAG laser 1064 nm in the long pulse mode in the treatment of signs of rosacea including the erythema of the face and telangiectasia.
- Trial name
- Nd:YAG (NCT06908915)
- Testing
- Nd:YAG laser 1064 nm
- Where
- Iraq
- Volunteers
- 30 people
- Sponsor
- Hawler Medical University
Erythematotelangiectatic Rosacea
Dose-Finding Study of CD07805/47 Topical Gel in Subjects With Erythematotelangiectatic Rosacea
This is a randomized, double-blind, parallel-group, vehicle-controlled, dose-finding study to investigate the pharmacodynamics and the safety of three dosages of CD07805/47 topical gel (0.07%, 0.18%, and 0.50%), after a single…
- Trial name
- NCT00989014
- Testing
- CD07805/47
- Where
- 5 sites in United States
- Volunteers
- 122 people
- Sponsor
- Galderma R&D
Erythematotelangiectatic Rosacea, Papulopustular Rosacea
Study to Evaluate the Efficacy and Safety of PAC-14028 Cream in Rosacea Patients
The objective of this study is to determine the efficacy and safety of PAC-14028 1% cream of Amorepacific Corporation in patients with erythema-telangiectatic or papulopustular rosacea
- Trial name
- NCT02052999
- Testing
- PAC-14028 cream 1%, Vehicle, Rozex gel 0.75%
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Amorepacific Corporation
Erythematotelangiectatic Rosacea
Feasibility Study: Ulthera System for the Treatment of Rosacea
Up to 12 subjects will be enrolled. Enrolled subjects will receive one or two Ultherapy treatments on the cheeks, depending on their assigned study group. Follow-up visits will occur 14, 30 and 90 days post-treatment.
- Trial name
- NCT01756027
- Testing
- Ulthera System providing one treatment per cheek, Ulthera System providing two treatments per cheek
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Ulthera, Inc
Rosacea, Papulopustular, Rosacea, Erythematotelangiectatic
Rosacea Radiofrequency Microneedling
There are 3 main objectives of this proposal as follows: (1) to assess the efficacy of radiofrequency microneedling in the treatment of erythematotelangiectatic and or papulopustular rosacea, (2) to determine the potential for…
- Trial name
- NCT06801717
- Testing
- KTP Laser Therapy, Radiofrequency microneedling
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Miami
Erythematotelangiectatic Rosacea, Papulopustular Rosacea
Open Label Pilot Study of Apremilast in Treatment of Rosacea
Rosacea is a chronic skin disorder with the signs and symptoms of facial flushing, persistent redness, small visible spider-like veins, papules (inflamed red bumps under the skin) and pustules.
- Trial name
- NCT01045551
- Testing
- Apremilast
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Julian M. Mackay-Wiggan
Rosacea, Erythematotelangiectatic
Topical Mitogenic-Activated Protein Kinase (MAPK) Inhibition in Rosacea
This is a prospective, vehicle controlled, double blinded study to evaluate the safety and potential efficacy of a topical formulation of a MEK inhibitor in patients with erythematotelangiectatic rosacea
- Trial name
- TOMIR (NCT05616923)
- Testing
- Trametinib
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Albany Research Institute, Inc.
Rosacea, Rosacea, Erythematotelangiectatic
Transcutaneous Auricular Vagus Nerve Stimulation Treatment for Rosacea
A single arm, pilot study among individuals with rosacea and at least moderate flushing or rednesss will be enrolled in a 4-week trial of taVNS.
- Conditions
- Rosacea, Rosacea, Erythematotelangiectatic, Flushing
- Trial name
- NCT07600424
- Testing
- Transaricular vagus nerve stimulation (taVNS)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Brigham and Women's Hospital
Papulopustular Rosacea, Erythematotelangiectatic Rosacea
A Therapeutic Equivalence Study of Two Metronidazole Gel 1% Topical Treatments of Rosacea
The purpose of this study is to compare the efficacy of two Metronidazole Gels 1%, in the treatment of Rosacea.
- Trial name
- NCT02393937
- Testing
- Reference: Metronidazole Gel 1%, Test: Metronidazole Gel 1%
- Where
- 27 sites in United States
- Volunteers
- 963 people
- Sponsor
- bioRASI, LLC
Erythematotelangiectatic Rosacea
The Efficacy and Safety of Anti-inflammation Treatment (Hirudoid Introduction Followed by Yellow Light Therapy) Combined With Tofacitinib and Doxycycline in Chinese Adult Patients With Mild to Moderate Erythematous Telangiectatic Rosacea
The efficacy and safety of anti-inflammation treatment (Hirudoid introduction followed by yellow light therapy) combined with tofacitinib and doxycycline in Chinese adult patients with mild to moderate erythematous telangiectatic…
- Trial name
- NCT07343635
- Testing
- Doxycycline, Hydroxychloroquine, Tofacitinib
- Where
- China
- Volunteers
- 186 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Erythematotelangiectatic Rosacea
Pulsed Dye Laser Treatment and Oxymetazoline Hydrochloride (HCL) 1% Cream for Erythematotelangiectatic Rosacea
This study will compare treatment outcome with pulsed dye laser, when used used as an adjunctive treatment to oxymetazoline HCl 1% cream, compared to oxymetazoline HCL 1% cream alone, for patients with moderate or severe…
- Trial name
- NCT04153188
- Testing
- The Vbeam® Prima System, Oxymetazoline HCL 1% Cream
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Rosacea
A Study to Determine Safety and Efficacy of B244 in Subjects With Mild to Moderate Rosacea
This is a Prospective, Vehicle Controlled, Double Blind, Multicenter, Randomized Phase II trial, comparing the effect of twice daily B244 application for 8 weeks vs. vehicle application on treatment of mild to moderate rosacea.
- Trial name
- NCT03590366
- Testing
- B244, Vehicle
- Where
- 9 sites in United States
- Volunteers
- 140 people
- Sponsor
- AOBiome LLC
Rosacea, Rosacea Subtype 1 (Erythematotelangiectatic)
Efficacy and Safety of Different Dose Regimens of Gabapentin for Treating Erythema/Flushing in Rosacea: A Randomized Controlled Trial
The goal of this clinical trial is to learn if Gabapentin works to treat flushing/erythema associated with rosacea. It will also learn about the safety of drug Gabapentin.
- Trial name
- Gabapenti (NCT06776445)
- Testing
- minocycline combined with hydroxychloroquine, gabapentin 300mg bid, gabapentin 300mg tid
- Where
- China
- Volunteers
- 50 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Erythematotelangiectatic Rosacea
Pulsed Dye Laser and Intense Pulsed Light Configured With Different Wavelength Bands in Improving Erythematotelangiectatic Rosacea
Pulsed dye laser(PDL) and intense pulsed light(IPL) has been widely used in improving rosacea. To compare the efficacy and safety of PDL and IPL configured with different wavelength bands(Delicate Pulsed Light, M22 590, M22…
- Trial name
- NCT05360251
- Testing
- PDL(595nm), IPL(DPL), IPL(M22 590)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Rosacea
Effect of CD07805/47 Gel in Rosacea Flushing
Phase 2a study to assess the efficacy and safety of CD07805/47 0.5% gel in the prevention of the flush of rosacea.
- Trial name
- NCT02300129
- Where
- Germany
- Volunteers
- 34 people
- Sponsor
- Galderma R&D