Clinical trials: Rotator Cuff Repair
Rotator Cuff Tears
Varying Bone Marrow-Derived Mesenchymal Stem Cells Concentrations' Impact on Rotator Cuff Repair Outcomes
Randomized controlled trial comparing benefits of varying amounts of proximal humerus-derived bone marrow aspirate and bone marrow concentrate in rotator cuff repair.
- Trial name
- NCT06361797
- Testing
- Rotator cuff repair augmented with whole bone marrow, Rotator cuff repair augmented with concentrated bone marrow
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Rotator Cuff Tear, Fatty Atrophy
Efficacy of an Amniotic Fluid Derived Allograft, (FlōGraft®) in Rotator Cuff Repairs: A Prospective Study
Rotator Cuff (RC) repair will be augmented with the injection of a human amniotic fluid derived allograft at the repair interface junction.
- Trial name
- NCT03379324
- Testing
- Superiority of augmented repairs, Fat degeneration of supraspinatus muscle
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Applied Biologics, LLC
Postoperative Pain, Adverse Effects
Continuous Interscalene Block Results in Superior Recovery Throughout the First Postoperative Week
The investigators undertook this prospective, randomized trial to compare the recovery profile throughout the first postoperative week in patients receiving continuous (CISB) interscalene brachial plexus block, single injection…
- Trial name
- NCT01881776
- Testing
- ISB
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Rotator Cuff Tear
Types of Fixation in Arthroscopic Rotator Cuff Repair
The study will identify if there is a difference of quality of life after surgery between two techniques used in surgery. The two different techniques are either the Single Row Fixation or the Double Row Fixation.
- Trial name
- NCT00508183
- Testing
- single row, double row fixation
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Rotator Cuff Tears, Rotator Cuff Rupture
Arthroscopic Rotator Cuff Repair Performed With Intraarticular Tranexamic Acid Could it Provide Improved Visual Clarity and Less Post-operative Pain? A Prospective, Double Blind, Randomized Study of 64 Patients.
Shoulder arthroscopy is widely used for treatment of different shoulder pathologies. Visual clarity is essential for successful and safe surgery.
- Conditions
- Rotator Cuff Tears, Rotator Cuff Rupture, Tranexamic Acid, Shoulder Arthroscopy
- Trial name
- NCT05453266
- Testing
- Application of Tranexamic acid in arthroscopic irrigation solution, No application of Tranexamic acid in arthroscopic irrigation solution
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Florence Nightingale Hospital, Istanbul
Rotator Cuff Tears
BioBrace® Implant for Arthroscopic Repair of Full Thickness Rotator Cuff Tears
This study aims to evaluate the safety and effectiveness of arthroscopic rotator cuff repair augmented with the BioBrace® Implant vs.
- Trial name
- REinForce (NCT05997381)
- Testing
- Arthroscopic rotator cuff repair with BioBrace® Implant augmentation., Arthroscopic rotator cuff repair
- Where
- United States
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- CONMED Corporation
Rotator Cuff Tear
Use of Graft Jacket for Rotator Cuff Repair
This study is to evaluate the safety and effectiveness of GraftJacket, a human tissue product used in fixing large and massive reparable rotator cuff tears.GraftJacket allograft (Wright Medical Technology, Inc., Arlington, TN) is…
- Trial name
- NCT00456781
- Testing
- Augmentation, Rotator Cuff Repair without augmentation
- Where
- 7 sites in United States, Canada
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Stryker Trauma and Extremities
Rotator Cuff Injuries, Cryotherapy Effect
Utility of Intermittent Cryo-Compression Versus Traditional Icing Following Arthroscopic Rotator Cuff Repair
Effective post - operative pain control following orthopedic surgical procedures without excessive reliance upon opioid pain medication has garnered increased attention in recent years.
- Trial name
- ICC (NCT05095909)
- Testing
- Cryo-compression, Cryo-therapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Allina Health System
Rotator Cuff Tear
Comparing Two Different Rehabilitation Protochols on Patients With Rotator Cuff Repair
Rotator cuff (RC) repair is one of the most common treatment approch to relief the pain and improve the shoulder function on patients with rotator cuff rupture.
- Trial name
- NCT03533088
- Testing
- Hospitalized rehabilitation, Home-based rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Rotator Cuff Tear
A Selective COX-2 Inhibitor Provides Pain Control But Hinders Healing Following Arthroscopic Rotator Cuff Repair
Selective cyclooxygenase (COX)-2 inhibitors are commonly used analgesics that provide similar analgesia but reduced adverse effects compared to other analgesics.
- Trial name
- NCT02850211
- Testing
- Celecoxib, Ibuprofen, Tramadol
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Vitamin D Deficiency, Rotator Cuff Tears
Vitamin D3 Supplementation for Vitamin D Deficiency in Rotator Cuff Repair Surgery
Rotator cuff injuries are the most common cause of shoulder disability and is increasingly more prevalent in the aging population.
- Trial name
- NCT05009498
- Testing
- Vitamin D3 supplementation
- Where
- 2 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Community Memorial Health System
Rotator Cuff Tear
Nonopioid Analgesia After Rotator Cuff Repair
This is a randomized, single blinded, standard of care controlled clinical trial. This project aims to compare postoperative pain control in patients in two treatment arms of rotator cuff repair: a treatment group given a…
- Trial name
- NCT03818919
- Testing
- Celecoxib, Ketorolac, Gabapentin
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Rotator Cuff Tear, Postoperative Pain
Liposomal Bupivacaine for Pain Control After Rotator Cuff Repair
The use of an interscalene block (ISB) is often associated with rebound pain that could be avoided through adjunctive therapy with longer duration.
- Trial name
- NCT03692546
- Testing
- Liposomal bupivacaine (LB)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Orthopaedic & Neurosurgery Specialists
Brachial Plexus Injury
Incidence of Brachial Plexus Injury After Rotator Cuff Repair With Continuous Interscalene Block
Brachial plexus injury after shoulder surgery with continuous interscalene block is 2.4% at 1 month and 0% at 6 months, but may be higher with a systematic postoperative neurological examination.
- Trial name
- NCT01334632
- Testing
- Continuous interscalene block, PCA morphine
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Rotator Cuff Injury
Post-Operative Quality of Life Evaluation for Different Anesthesia Techniques for Arthroscopic Shoulder Surgery
Randomized controlled trial on efficacy of single injection or continuous interscalene brachial plexus block on analgesia in patients having outpatient rotator cuff surgery.
- Trial name
- NCT01355757
- Testing
- Baxter INFUSOR System, Single Injection of Local Anesthetic
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Shoulder Injuries, Rotator Cuff Injuries
Subscap Reverse Shoulder Arthroplasty
The subscapularis is part of the rotator cuff and is release as part of a reverse shoulder replacement. The decision to repair this tendon is controversial.
- Trial name
- NCT05344898
- Testing
- Subscap Tenotomy, Subscap Repair
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Early Retears and Clinical Outcomes Following Surgical Repair of Massive Rotator Cuff Tears
Postoperative USG Control and Clinical Follow-up of Massive Rotator Cuff Tendon Ruptures
This prospective observational study aims to investigate the tendon integrity and clinical outcomes following surgical repair of massive rotator cuff tears.
- Trial name
- NCT07004218
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gazi University
C. Acnes, Phototherapy
Photodynamic Therapy for Cutibacterium Acnes (C. Acnes) Decolonization of the Shoulder Dermis
This is a prospective, randomized controlled trial to evaluation the ability of 5-aminolevulinic acid HCL topical solution photodynamic therapy to decrease the colonization of Cutibacterium acnes (C.
- Conditions
- C. Acnes, Phototherapy, Postoperative Infection, Arthroscopic Rotator Cuff Repair
- Trial name
- NCT04636242
- Testing
- Skin Biopsy, 5 Aminolevulinic Acid + Phototherapy
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Rotator Cuff Tears, Motor Imagery
Does MI Have a Therapeutic Role in Arthroscopic Rotator Cuff Repair?
Objective: The aim of this study is to investigate the effect of motor imagery on muscle activity, pain, and function in arthroscopic rotator cuff repair.
- Conditions
- Rotator Cuff Tears, Motor Imagery, Muscle Activity, Atrophy, Muscular
- Trial name
- NCT05670080
- Testing
- Motor Imagery, Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Pain
The Effect of Dexamedetomidine for Interscalene Brachial Plexus Block on Plasma Biomarkers After Rotator Cuff Repair
The present study was designed to test the hypothesis that dexmedetomidine added to ropivacaine for interscalene brachial plexus blocks for elective shoulder surgery would enhance the duration and effect of analgesia when…
- Trial name
- NCT02766556
- Testing
- dexmedetomidine, ISB, Ropivacaine
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chuncheon Sacred Heart Hospital