Clinical trials: Rotator Cuff Tear Surgical Repair
Rotator Cuff Tears, Shoulder Surgery
Regeneten Patch vs Standard Care in Partial Thickness Rotator Cuff Repair
Shoulder pain is a common complaint with the most common reason being tendinopathy and/or tearing of the rotator cuff. While many rotator cuff tears are often considered normal, age-related degenerative disorders, with either…
- Trial name
- NCT04673344
- Testing
- Regeneten Collagen Patch
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Rotator Cuff Injury, Pain
Pre-emptive Opioid Treatment to Prevent Rebound Pain After Arthroscopic Rotator Cuff Repair and/or Acromioplasty Under General Anesthesia and Interscalene Block
Arthroscopic shoulder rotator cuff repair and acromioplasty are associated with severe postoperative pain. The interscalene block (ISB) is commonly used for this type of surgery, providing analgesia by anesthetizing the nerves…
- Trial name
- NCT02939209
- Testing
- Hydromorphone Hcl 2Mg Tab
- Where
- 2 sites in Canada
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Vishal Uppal
Rotator Cuff Tear, Tendon Injuries
Mesenchymal Stem Cells in Rotator Cuff Repair
Randomized clinical study involving 44 patients, evaluating the effect of mesenchymal cells on rotator cuff repair. The primary outcome will be post-operative MRI tendon integrity and secondary outcomes clinical assessment by the…
- Conditions
- Rotator Cuff Tear, Tendon Injuries, Mesenchymal Stem Cell
- Trial name
- NCT03362424
- Testing
- Mesenchymal stem cell, Rotator cuff repair
- Where
- Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Rotator Cuff Tears, Shoulder Pain
Liposomal Bupivacaine Plus Bupivacaine Peripheral Nerve Blockade Versus Ropivacaine Plus Dexamethasone Peripheral Nerve Blockade for Arthroscopic Rotator Cuff Repair
This study is a comparison of analgesia effect from peripheral nerve blockade (PNB) with liposomal bupivacaine combined with bupivacaine compared to PNB with ropivacaine combined with dexamethasone for arthroscopic rotator cuff…
- Trial name
- NCT04737980
- Testing
- Liposomal bupivacaine, Bupivacaine Hcl 0.5% Inj, Ropivacaine 0.5% Injectable Solution
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery Florida
Rotator Cuff Tear
Rotator Cuff Repair Using Standard Double Row Technique With Platelet Rich Fibrin Membrane vs. Standard Double Row Technique
This study is a single-blind, randomized study evaluating the 6 month and 2 year outcomes of patients treated with arthroscopic rotator cuff repair using one of two techniques.
- Trial name
- RCRPRFM (NCT02256891)
- Testing
- PRFM, Double Row
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Rotator Cuff Tears
Ortho-R® for Rotator Cuff Repair Compared With Standard of Care Rotator Cuff Repair Without Ortho-R®
Phase I/II, multi-center, prospective, blinded 2arm, parallel design and randomized controlled study. Assessing the Ortho-R/PRP combination and standard of care for rotator cuff repair, will be compared though 12 months.
- Trial name
- NCT05333211
- Testing
- Ortho-R/PRP
- Where
- 9 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- ChitogenX Inc
Shoulder Pain Chronic, Shoulder Pain
Arthroscopic Transosseous vs. Anchored Rotator Cuff Repair
This study will compare arthroscopic transosseous versus anchored rotator cuff repairs in terms of clinical outcomes, rotator cuff integrity, and cost-effectiveness.
- Conditions
- Shoulder Pain Chronic, Shoulder Pain, Rotator Cuff Tear, Rotator Cuff Injury
- Trial name
- NCT03797287
- Testing
- Tensor Tunnler, Anchor Rotator Cuff Repair
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Rotator Cuff Tear
Influence of Intraoperative Repair Tension on Postoperative Healing of Full-thickness Rotator Cuff Tears
Relevant problems of rotator cuff repair: High retear rate after rotator cuff repair of 13%, despite regard of the criteria for "reparability" of a tear.
- Trial name
- TENS-RCT (NCT03318627)
- Testing
- Sterile Spring Scale
- Volunteers
- healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Rotator Cuff Tears
Shoulder Functional Performance After Shoulder Surgery
Rotator Cuff (RC) injuries are a progressive clinical condition that starts with an acute tendonitis, continues with partial thickness rupture and results in a full thickness rupture in the advanced period.
- Trial name
- NCT04388306
- Testing
- Shoulder Performance Test- Functional Impairment Test-Head and Neck, Shoulder, Arm (FIT-HaNSA)
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Rotator Cuff Tear
Impact of Postoperative Management on Outcomes and Healing of Rotator Cuff Repairs
Rotator cuff tears are seen in 40% of subjects over age 50 57, with a prevalence known to increase with each decade of life 51. Each year rotator cuff disorders lead to 4.5 million physician visits, 40,000 inpatient surgeries…
- Trial name
- NCT01383239
- Testing
- Immediate Postoperative Therapy, Delayed Physical Therapy
- Where
- 9 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Rotator Cuff Tear
Postoperative Pain After Intravenous Vitamin C Injection for Arthroscopic Rotator Cuff Repair
1. Treatment of rotator cuff tear The rotator cuff tear is the most demanding part of the shoulder surgery. Rotator cuff degeneration is thought to be the largest cause of rotator cuff tear.
- Trial name
- VITCRCR (NCT02992028)
- Testing
- Intravenous Nutrition (Vitamins) injection, Intravenous Saline injection
- Where
- South Korea
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Himchan Hospital
Rotator Cuff Tears
Fascial Release After Arthroscopic Rotator Cuff Repair
Instrument-assisted soft tissue mobilization (IASTM) is a popular treatment method that can be used for myofascial restriction and fascial release.
- Trial name
- NCT06088667
- Testing
- Fascial mobilization group
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Rotator Cuff Tears, Rotator Cuff Injuries
Clinical Outcomes Related to Arthroscopic Rotator Cuff Repair Recovery Using Incrediwear
To assess the benefits of using the Incrediwear products for patients recovering from Arthroscopic Rotator Cuff Repair surgery for postoperative pain, range of motion, and swelling.
- Conditions
- Rotator Cuff Tears, Rotator Cuff Injuries, Rotator Cuff Arthropathy of Left Shoulder (Disorder), Rotator Cuff Arthropathy of Right Shoulder (Disorder)
- Trial name
- NCT06669741
- Testing
- Shoulder Sleeve
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Texas Bone and Joint
Rotator Cuff Tear
Decellularized Human Placental Extracellular Matrix Tissue for Rotator Cuff Repair Augmentation
The rotator cuff is a set of muscles and tendons that help move the shoulder. Tears in the rotator cuff are common, particularly as people age. Consequently, rotator cuff repair surgeries are common, as well.
- Trial name
- ECMRCR (NCT07027735)
- Testing
- Rotator Cuff Repair with Allograft Patch, Rotator Cuff Repair with No Augmentation
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Columbia University
Rotator Cuff Tear Arthropathy, Rotator Cuff Tear
Abduction Brace Versus Antirotation Sling for Immobilization Following Reverse Shoulder Arthroplasty and Rotator Cuff Repair
To compare the functional and anatomical outcomes, and patient satisfaction and compliance between two different postoperative immobilization methods - abduction shoulder brace versus simple arm sling - following 2 common…
- Trial name
- NCT03488433
- Testing
- Abduction brace, Antirotation sling
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Rotator Cuff Tears, Central Sensitisation
Effect of Pregabalin on Shoulder Pain in Patients With Central Sensitization After Arthroscopic Rotator Cuff Repair
This study aims to investigate the effects of Pregabalin intake on shoulder pain management in patients with central sensitization undergoing arthroscopic rotator cuff repair.
- Conditions
- Rotator Cuff Tears, Central Sensitisation, Neuropathic Pain
- Trial name
- NCT06367998
- Testing
- Pregabalin
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Rotator Cuff Tears
Varying Bone Marrow-Derived Mesenchymal Stem Cells Concentrations' Impact on Rotator Cuff Repair Outcomes
Randomized controlled trial comparing benefits of varying amounts of proximal humerus-derived bone marrow aspirate and bone marrow concentrate in rotator cuff repair.
- Trial name
- NCT06361797
- Testing
- Rotator cuff repair augmented with whole bone marrow, Rotator cuff repair augmented with concentrated bone marrow
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Rotator Cuff Tear, Fatty Atrophy
Efficacy of an Amniotic Fluid Derived Allograft, (FlōGraft®) in Rotator Cuff Repairs: A Prospective Study
Rotator Cuff (RC) repair will be augmented with the injection of a human amniotic fluid derived allograft at the repair interface junction.
- Trial name
- NCT03379324
- Testing
- Superiority of augmented repairs, Fat degeneration of supraspinatus muscle
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Applied Biologics, LLC
Rotator Cuff Tear
Types of Fixation in Arthroscopic Rotator Cuff Repair
The study will identify if there is a difference of quality of life after surgery between two techniques used in surgery. The two different techniques are either the Single Row Fixation or the Double Row Fixation.
- Trial name
- NCT00508183
- Testing
- single row, double row fixation
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Rotator Cuff Tears, Rotator Cuff Rupture
Arthroscopic Rotator Cuff Repair Performed With Intraarticular Tranexamic Acid Could it Provide Improved Visual Clarity and Less Post-operative Pain? A Prospective, Double Blind, Randomized Study of 64 Patients.
Shoulder arthroscopy is widely used for treatment of different shoulder pathologies. Visual clarity is essential for successful and safe surgery.
- Conditions
- Rotator Cuff Tears, Rotator Cuff Rupture, Tranexamic Acid, Shoulder Arthroscopy
- Trial name
- NCT05453266
- Testing
- Application of Tranexamic acid in arthroscopic irrigation solution, No application of Tranexamic acid in arthroscopic irrigation solution
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Florence Nightingale Hospital, Istanbul