Clinical trials: Roux- en -y Gastric Bypass
Obesity
Effect of Diet Versus Sleeve Gastrectomy and Gastric Bypass on Appetite
The biggest challenge in obesity management is maintaining weight loss in the long-term. Currently, bariatric surgery is the most effective treatment, leading to sustained weight loss that is not yet achievable with lifestyle…
- Trial name
- DISGAP (NCT04051190)
- Testing
- VLED group, Sleeve Gastrectomy group, Gastric Bypass group
- Where
- 2 sites in Norway
- Volunteers
- 54 people
- Sponsor
- Norwegian University of Science and Technology
Malignant Gastric Outlet Obstruction
Roux-en-Y Gastric Bypass Versus Loop Gastrojejunostomy for Malignant Gastric Outlet Obstruction
This study is intended to investigate whether roux-en-y bypass surgery is superior to conventional loop gastrojejunostomy for Malignant gastric outlet obstruction in terms of tolerance to solid food intake.
- Trial name
- NCT05986890
- Testing
- Roux-en-Y Bypass, gastrojejunostomy
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Corewell Health West
Type II Diabetes in Subjects BMI 27 to 32
Roux-en-Y Gastric Bypass for BMI 27-32 Type 2 Diabetes Versus Best Medical Treatment
Investigators aim to show that Roux-en-Y Gastric Bypass (RYGB) is superior to best medical treatment in reaching well-defined treatment end points in Asian subjects of BMI 27-32 with type 2 Diabetes (DM2).
- Trial name
- NCT02041234
- Testing
- Roux-en-Y Gastric Bypass (RYGB), Incretin analogues, Xenical
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- Khoo Teck Puat Hospital
Gastroesophageal Reflux Disease, Morbid Obesity
Gastroesophageal Reflux Disease (GERD) Before and After Gastric Bypass
The hypothesis of this study was that gastric bypass (GBP) ameliorates gastroesophageal reflux disease (GERD) in morbidly obese patients.
- Trial name
- NCT00951093
- Testing
- Gastric bypass
- Where
- Brazil
- Volunteers
- 53 people
- Sponsor
- Clinica Gastrobese
Morbid Obesity, Postoperative Pain
Patients-Controlled Epidural Analgesia After Gastric Bypass for Morbid Obesity Using Morphine-Levobupivacaine Regimens
Adequate postoperative analgesia can facilitate recovery following gastric bypass surgery for morbid obesity. The efficacy and safety of intravenous patient - controlled analgesia has been studied, but up to date no data are…
- Conditions
- Morbid Obesity, Postoperative Pain, Postoperative Bowel Function, Postoperative Ambulation
- Trial name
- NCT01249872
- Testing
- GROUP A : 0 mg MORPHINE-0.1% LEVOBUPIVACAINE, GROUP B : 1 mg MORPHINE- 0.1% LEVOBUPIVACAINE, GROUP C : 2 mg MORPHINE-0.1% LEVOBUPIVACAINE
- Where
- Greece
- Volunteers
- 96 people
- Sponsor
- University of Patras
Bariatric Surgery, Morbid Obesity
Pharmacokinetics of Rivaroxaban After Bariatric Surgery
Data on pharmacokinetics of rivaroxaban after bariatric surgery and in morbid obesity are sparse. The aim of this study is to assess the pharmacokinetic and pharmacodynamic parameters of rivaroxaban, used at a therapeutic…
- Trial name
- ABSORB (NCT04180436)
- Testing
- rivaroxaban 20 mg once daily 8 days
- Where
- France
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Bariatric Surgery, Hormonal Response
Comparison of Hormonal Response to a Mixed-Meal Tolerance Test After Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic Sleeve Gastrectomy With Duodenojejunal Bypass in Patients With Super Morbid Obesity
Obesity is a major global health problem. Bariatric surgery is the most effective treatment, leading to substantial weight loss and improvement in obesity-related comorbidities.
- Conditions
- Bariatric Surgery, Hormonal Response, Post Bariatric Hypoglycemia
- Trial name
- CU BYPASS-DJB (NCT07747779)
- Testing
- Sleeve gastrectomy with duodenojejunal bypass, Roux-en-Y gastric bypass
- Where
- Thailand
- Volunteers
- 32 people
- Sponsor
- Chulalongkorn University
Obesity
Changes in Body- and Liver-composition During Low Calorie Diet in Morbidly Obese
The purpose of this study is to determine what changes occur in body- and liver-composition during four weeks of low calorie diet in morbidly obese females
- Trial name
- NCT01842425
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Uppsala University
Obesity
A Preliminary Comparison of the Blood Levels of Medications in Obese Subjects Compared to Post-Gastric Bypass Subjects
The purpose of this study is to determine the difference, if any, in the area under the sertraline plasma level time curve (AUC) between patients who are nine to fifteen months post Roux-en-Y Bariatric Surgery and control…
- Trial name
- NCT01015976
- Testing
- bariatric surgery, control
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Neuropsychiatric Research Institute, Fargo, North Dakota
Obesity (Disorder)
Three M Study (Malabsorption, Microbiota, Mini-Gastric Bypass)
Bariatric surgery represents the best therapeutic option to induce sustainable weight loss and to solve serious comorbidities improving the life-expectancy and the quality of life.
- Trial name
- NCT03412149
- Testing
- Mini Gastric Bypass, Roux en Y Gastric Bypass
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Morbid Obesity, Insulin Resistance
Assessment of Insulin Resistance, NAFLD, Predictors of CV Morbidity, and Subcutaneous Adipose and Visceral Adipose Gene Expression in Patients Undergoing Gastric Bypass Surgery
The purpose of this research is to further study the effect weight loss after gastric bypass surgery has on the heart and blood pressure and on how the body uses or metabolizes the sugars, fats and proteins we eat.
- Conditions
- Morbid Obesity, Insulin Resistance, Non-Alcoholic Fatty Liver Disease
- Trial name
- NCT01007955
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Massachusetts, Worcester
Complications After Gastric Bypass Operation
Complications After Bariatric Surgery - a Clinical Trial
The number of obese is increasing rapidly. Bariatric surgery is used to a greater and greater extent as treatment of obesity to obtain a greater and more permanent weight loss.
- Trial name
- NCT01930838
- Testing
- Gastric bypass operation
- Where
- Denmark
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Aarhus
Obesity, Morbid, Obesity, Abdominal
Long-term Follow-up After OAGB
This study follows patients who have undergone one-anastomosis gastric bypass (OAGB), a type of weight-loss surgery, to check for changes in the stomach and esophagus over time.
- Conditions
- Obesity, Morbid, Obesity, Abdominal, Ona Anastomosis Gastric Bypass, GERD
- Trial name
- NCT07125638
- Where
- Italy
- Volunteers
- 2,368 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Obesity, Obesity, Morbid
Biological Sample Repository for Gastrointestinal Disorders
The goal of this observational study has the purpose of collecting biological samples from obese patients undergoing evaluation for weight loss by means of medical or endoscopic therapies; and of post bariatric surgery patients…
- Conditions
- Obesity, Obesity, Morbid, Obesity, Primary, Gastro-Intestinal Disorder
- Trial name
- NCT05874726
- Testing
- Blood Collection, Urine Collection, Tissue Sample Collection
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Pichamol Jirapinyo, MD, MPH
Bariatric Surgery Candidate
Rates and Severity of PONV for Neuromuscular Block Reversal in Patients Receiving Gastric Bypass Bariatric Surgery
Patients who require bariatric surgery frequently bring a panoply of pre-existing comorbidities to the operating theatre. With body mass indices routinely in the 50s and 60s, patients who have bariatric surgery frequently have…
- Trial name
- NCT03432845
- Testing
- compare reversal agents
- Sponsor
- WellSpan Health
Severe Obesity, Renal Failure
Obesity Surgery and Kidney Transplant for Patients With Obesity and Renal Failure
Gastric Bypass followed by renal transplantation is superior to medical management followed by renal transplant for patients with severe obesity and renal failure.
- Trial name
- NCT02128802
- Testing
- Gastric Bypass, Weight Loss Program
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Vanderbilt University Medical Center
The Prevalence of Surgery for Small Bowel Obstruction After LGBP Procedure.
Internal Hernia After Laparoscopic Gastric Bypass
To see if closing the mesenteric defects created at a Laparoscopic Gastric Bypass is better than leaving them open.
- Trial name
- NCT01137201
- Testing
- Suturing of mesenteric defects
- Where
- Sweden
- Volunteers
- 2,507 people
- Sponsor
- Region Örebro County
Bariatric Surgery Candidate, Obesity
Comparing 150cm OAGB With 150cm Biliopancreatic Limb RYGB. A Non-inferiority Trial
The purpose of this study is to assess the safety and efficiency of OAGB compared to RYGB
- Conditions
- Bariatric Surgery Candidate, Obesity, Obesity, Morbid
- Trial name
- Roux-en-WHY? (NCT04852198)
- Testing
- OAGB, RYGB
- Where
- 2 sites in Netherlands
- Volunteers
- 298 people
- Sponsor
- Flevoziekenhuis
Pain, Obesity
The Effect of Pre-Operative Transversus Abdominis Plane (TAP) Block in the Post Operative Opioid Consumption in Morbid Obese Patients Undergoing Laparoscopic Gastric Bypass Surgery: A Prospective,Randomized, Blinded Study
The use of preoperative TAP block in laparoscopic bariatric surgery can improve the postoperative pain and quality of recovery in patients undergoing these procedures.
- Conditions
- Pain, Obesity, Surgery
- Trial name
- NCT01075087
- Testing
- (study group) will receive a bilateral TAP block using 20 cc of 0.5% ropivacaine on each side.
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Northwestern University
Bariatric Surgery
30-Days Post-Operative Complications in Bariatric Surgery
comparison of 30-days post-operative outcomes of laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB)
- Trial name
- Bariatric (NCT04779723)
- Testing
- Comparison of two Techniques of bariatric surgery
- Where
- Pakistan
- Volunteers
- 116 people
- Sponsor
- Multan Medical And Dental College