Clinical trials: Roux- en -y Gastric Bypass
Internal Hernia
CTA for Internal Herniation After RYGB Surgery
Introduction: Morbid obesity, defined as a body mass index (BMI) of over 40 kg/m2, is globally an imminent health threat. Conservative therapies do often not yield the desired result.
- Trial name
- CTA-IH (NCT03114761)
- Testing
- CT angiography
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Rijnstate Hospital
Roux en Y Gastric Bypass Surgery
Pharmacokinetic Properties of Sertraline Before and After Gastric Bypass Surgery
This study is being conducted to evaluate how the body absorbs and processes the medication sertraline (Zoloft®) before compared to how it is absorbed at two time points after gastric bypass surgery.
- Trial name
- NCT01214382
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- North Dakota State University
Obesity
Effect of Gastric Bypass Surgery on Pancreatic Islet and Incretin Function - Follow-up Study
To examine pancreatic islet function and incretin function during intravenous and oral stimulation >2 years after gastric bypass surgery in patients with normal glucose tolerance.
- Trial name
- NCT02161666
- Where
- Denmark
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Obesity, Sleep Apnea, Obstructive
The Effect of Obstructive Sleep Apnea on Medical Outcomes After Gastric Bypass Surgery
Obstructive sleep apnea (OSA) is a syndrome characterized by repetitive episodes of airway obstruction during sleep, which result in low oxygen level in the blood and bad sleep quality.
- Trial name
- NCT00671983
- Testing
- Neurocognitive Testing
- Where
- United States
- Sponsor
- Stanford University
Obesity
Comparison of Two Surgical Techniques for Treatment of Type III Obesity (BMI 40-50 kg/m2): Single Anastomosis Duodenoileal Bypass With Sleeve Gastrectomy and Roux-en-Y Gastric Bypass.
Roux-en-Y gastric bypass (RY-GBP) is one of the surgical techniques most widely used for the treatment of obesity. Long series of operated patients published in the literature have demonstrated its safety and efficacy.
- Trial name
- BYPSADIS (NCT06789965)
- Testing
- SADI-S, RY-GBP
- Where
- Spain
- Volunteers
- 450 people
- Sponsor
- Hospital Clinic of Barcelona
Morbid Obesity
Clinical and Health Economic Impact of Robot-assisted Surgery vs Conventional Laparoscopy : the Case of Gastric Bypass
The purpose of this study is to gather clinical and economic evidence on the use of robotics for bariatric surgery (gastric bypass).
- Trial name
- NCT01760512
- Testing
- Gastric bypass
- Where
- France
- Volunteers
- 118 people
- Sponsor
- IHU Strasbourg
Gastric Bypass Surgery, Revisional Bariatric Surgery
Reversal of Roux-en-Y Gastric Bypass: A Swedish National Cohort Study
Objective: To investigates incidence, indications, symptom relief, complications, and weight outcomes after Roux-en-Y gastric bypass (RYGB) reversal.
- Conditions
- Gastric Bypass Surgery, Revisional Bariatric Surgery, Complications After Bariatric Surgery
- Trial name
- NCT07347093
- Where
- Sweden
- Volunteers
- 199 people
- Sponsor
- Vrinnevi Hospital
Obesity
Long-Term Follow-up of Ohio State University Medical Center (OSUMC) Bariatric Patients
Obtain long-term follow-up results for bariatric patients who underwent medical management or surgery for treatment of morbid obesity by Ohio State University Medical Center (OSUMC).
- Trial name
- NCT00700843
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Ohio State University
Obesity
Endostapler Gastric Bypass Study
The goal of this prospective, post-market study is to evaluate safety and efficacy of the AEON™ Endostapler when used in laparoscopic Roux-en-Y gastric bypass surgery.
- Trial name
- NCT04712526
- Testing
- AEON Endostapler
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lexington Medical Inc.
Bariatric Surgery, Micronutrient Deficiencies
Supplementation After Bariatric Surgery
The aim of this study is to assess medication adherence to vitamin and mineral supplements after bariatric surgery and identify factors that may influence adherence.
- Conditions
- Bariatric Surgery, Micronutrient Deficiencies, Obesity
- Trial name
- NCT04412421
- Testing
- Gastric Bypass, Sleeve Gastrectomy
- Where
- Sweden
- Volunteers
- 260 people
- Sponsor
- Region Östergötland
Severe Obesity
Effects of Bile Acids on GLP-1 Secretion After Roux-en-Y Gastric Bypass
The purpose of this study is to examine the effects of bile acids on GLP-1 secretion after Roux-en-Y gastric bypass.
- Trial name
- NCT02340247
- Testing
- Water, Ursodeoxycholic Acid, Chenodeoxycholic Acid
- Where
- Denmark
- Volunteers
- 11 people
- Sponsor
- Hvidovre University Hospital
Roux-en-Y Gastric Bypass, Obesity
Assessing the Safety and Performance of the easyEndoTM Universal Linear Cutting Stapler in Laparoscopic Gastric Bypass Surgery
The purpose of this observational registry is to evaluate the safety and performance of the easyEndoTM Universal Linear Cutting Stapler and reloads from Ezisurg Medical used in laparoscopic RYGB surgery to create anastomoses.
- Trial name
- NCT03968757
- Testing
- easyEndoTM Universal Linear Cutting Stapler and reloads (Ezisurg Medical)
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Duomed
Obesity
Impact of Laparoscopic Gastric Bypass Surgery and Weight Reduction on Lower Esophageal Sphincter (LES)
The purpose with this study is to investigate whether gastric bypass surgery and the following weight reduction impact the tone in esophageal sphincters and the esophageal function.
- Trial name
- NCT01672034
- Testing
- Laparoscopic gastric bypass surgery
- Where
- Sweden
- Sponsor
- Örebro University, Sweden
Obesity, Morbid, Type 2 Diabetes Mellitus (T2DM)
Comparative Outcomes of One-Anastomosis Gastric Bypass and Roux-en-Y Gastric Bypass As Revisional Procedures Following Failed Restrictive Bariatric Surgery
Study Description This prospective, multicenter study aims to compare the outcomes of One-Anastomosis Gastric Bypass (OAGB) and Roux-en-Y Gastric Bypass (RYGB) as revisional procedures for patients experiencing insufficient…
- Conditions
- Obesity, Morbid, Type 2 Diabetes Mellitus (T2DM), Hypertension, Dyslipidemia
- Trial name
- COBRA stady (NCT06794892)
- Where
- Italy
- Volunteers
- 328 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Morbid Obesity
Comparison of Mini Gastric Bypass and Roux-en-Y Gastric Bypass
This study compares Roux-en-Y gastric bypass with single anastomosis gastric bypass in a randomized prospective setting. This study also adresses the issue of bile reflux after MGB.
- Trial name
- RYSA (NCT02882685)
- Testing
- Roux-en-y gastric bypass, Single anastomosis gastric bypass
- Where
- 2 sites in Finland
- Volunteers
- 120 people
- Sponsor
- Helsinki University Central Hospital
Morbid Obesity, Insulin Resistance
Assessment of Insulin Resistance, NAFLD, Predictors of CV Morbidity, and Subcutaneous Adipose and Visceral Adipose Gene Expression in Patients Undergoing Gastric Bypass Surgery
The purpose of this research is to further study the effect weight loss after gastric bypass surgery has on the heart and blood pressure and on how the body uses or metabolizes the sugars, fats and proteins we eat.
- Conditions
- Morbid Obesity, Insulin Resistance, Non-Alcoholic Fatty Liver Disease
- Trial name
- NCT01007955
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Massachusetts, Worcester
Morbid Obesity
Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic Sleeve Gastrectomy
The sleeve gastrectomy that has been utilized as a first-stage bariatric procedure to reduce surgical risk in high-risk patients by induction of weight loss is now gaining popularity as a standalone procedure for the treatment of…
- Trial name
- NCT00667706
- Testing
- laparoscopic operation Sleeve Gastrectomy, laparoscopic operation Roux-en-Y Gastric bypass
- Volunteers
- 200 people
- Sponsor
- Hadassah Medical Organization
Iron Deficiency Anemia
Trial of IV vs Oral Iron Treatment of Iron Deficiency Anemia in the Post-Operative Bariatric Surgical Patient
Given the limited long-term effectiveness of traditional weight loss methods, bariatric surgery is increasingly becoming the preferred option for sustained weight loss.
- Trial name
- NCT04268849
- Testing
- Ferumoxytol, Saline, Ferrous sulfate tablets
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Auerbach Hematology Oncology Associates P C