Clinical trials: SAPHO Syndrome
SAPHO Syndrome
Study of the Pathophysiological Mechanisms Involved in the SAPHO Syndrome: Genetic Component and Immune Response
SAPHO syndrome (Synovitis, Acne, Pustulosis, Hyperostosis and Osteitis) is a chronic inflammatory rheumatism associating bone or joint lesions and dermatological manifestations dominated by severe acne and palmar and palmoplantar…
- Trial name
- SAPHO-Screen (NCT07081880)
- Testing
- biological sampling
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Psoriasis Arthritis, SAPHO Syndrome
Typological Study of Sleep Pathologies During Psoriatic Rheumatism and SAPHO Syndrome: Prospective Study Within the Paris Saint-Joseph Hospital Group"
Chronic inflammatory rheumatisms (CIR) are a source of motor disability and various comorbidities, particularly cardiovascular and metabolic. They also significantly impact patients' quality of life, including sleep disturbances.
- Conditions
- Psoriasis Arthritis, SAPHO Syndrome, Sleep Apnea Syndromes
- Trial name
- SleepSO2 (NCT07086599)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Fondation Hôpital Saint-Joseph
SAPHO Syndrome
Characterizing SAPHO With 68Ga-FAPI PET/CT
68Ga-FAPI has been developed as a tumor-targeting agent as fibroblast activation protein is overexpressed in cancer-associated fibroblasts and some inflammation.
- Trial name
- NCT04596462
- Testing
- 68Ga-FAPI
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Peking Union Medical College Hospital
Immune System Disease, Musculoskeletal Disease
Chronic Non-bacterial Osteomyelitis Treated With Pamidronate
In a randomized double blind placebo controlled trial to investigate the effect of pamidronate in treatment of chronic non bacterial osteomyelitis. Main objective: 1.
- Trial name
- CNOPAM (NCT02594878)
- Testing
- Pamidronatdinatrium, Natrium chloride 9mg/ml
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- University of Aarhus
SAPHO Syndrome
Study of the Efficacy and Safety of Etanercept Treatment in Patients With SAPHO Syndrome
The study includes adult patients with SAPHO syndrome (ORPHA: 793), meeting the modified classification criteria according to Kahn (2003), with the ineffectiveness of standard treatment (patient's global assessment of the disease…
- Trial name
- SAPHO (NCT06011889)
- Testing
- Etanercept
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland
SAPHO Syndrome
Efficacy of Bisphosphonates in Patients With Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis (SAPHO) Syndrome
This study is designed to evaluate long term efficacy of intravenous bisphosphonates for bone marrow edema in patients with SAPHO syndrome.
- Trial name
- NCT02544659
- Testing
- pamidronate disodium
- Volunteers
- 30 people
- Sponsor
- Peking Union Medical College Hospital
SAPHO Syndrome
Immune Response in the SAPHO Syndrome
The aetiology of SAPHO syndrome seems to involve genetic, infectious and immunological components. The investigators examined innate and adaptative immune responses in SAPHO syndrome as compared with psoriatic arthritis and…
- Trial name
- NCT01688219
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris