Clinical trials: SARCOIDOSIS
Sarcoidosis
A Study of Adalimumab to Treat Sarcoidosis of the Skin
The purpose of this study is to determine if adalimumab is an effective for the skin manifestations of sarcoidosis.
- Trial name
- NCT00274352
- Testing
- adalimumab
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Pariser, Robert J., M.D.
Sarcoidosis
Test-retest Reliability for Fatigue Assessment Scale, Short Form 6 Dimension and King's Sarcoidosis Questionnaire
This study aims to see if people's health related quality of life (how they feel about their health) changes over a 12 week period if they do not receive any change in their medicines.
- Trial name
- NCT04508361
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of East Anglia
Cardiac Sarcoidosis, Sarcoidosis
Cardiac Sarcoidosis Randomized Trial
Prospective randomized controlled trial comparing low dose Prednisone(or Prednisolone)/Methotrexate combination to standard dose Prednisone(or Prednisolone) in patients diagnosed with acute active clinically manifest cardiac…
- Trial name
- CHASM-CS-RCT (NCT03593759)
- Testing
- Prednisone or Prednisolone, Methotrexate
- Where
- 31 sites in United States, Canada and 3 more
- Volunteers
- 160 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Sarcoidosis, Pulmonary, Telerehabilitation
Feasibility & Effect of a Tele-rehabilitation Program in Pulmonary Sarcoidosis Pulmonary Sarcoidosis
Pulmonary sarcoidosis (PS) is defined as a multisystem granulomatous disorder of unknown cause affecting different vital organs, especially the lungs. PS manifest in reduction of pulmonary function.
- Trial name
- TeleSarco (NCT03914027)
- Testing
- Telerehabilitation
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Aarhus University Hospital
Arrhythmogenic Right Ventricular Cardiomyopathy, Cardiomyopathies
Mayo AVC Registry and Biobank
Arrhythmogenic ventricular cardiomyopathy (AVC) is a genetic condition which affects the heart and can lead to heart failure and rhythm problems, of which, sudden cardiac arrest or death is the most tragic and dangerous.
- Conditions
- Arrhythmogenic Right Ventricular Cardiomyopathy, Cardiomyopathies, Heart Diseases, Cardiovascular Diseases
- Trial name
- NCT03049254
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Sarcoidosis, Cardiac
A Study to Assess the Safety, Tolerability, and Efficacy of Namilumab in Participants With Active Cardiac Sarcoidosis
A Randomized, Double-blind, Placebo-controlled, Study with an Open-label Cohort.
- Trial name
- RESOLVE-Heart (NCT05351554)
- Testing
- Namilumab
- Where
- 12 sites in United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Kinevant Sciences GmbH
Muscular Sarcoidosis
Effect of Schisandra Chinensis Extract on Musculoskeletal Biomakers in Relatively Sarcopenic Adults: a RCT
The investigators conduct a randomized, double-blind, placebo-controlled study to investigate the effects of the SCE on muscle strength, muscle mass, and muscle function in healthy adults for 12 weeks.
- Trial name
- NCT03402308
- Testing
- Schisandra chinensis extract
- Where
- South Korea
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Sarcoid Uveitis
Lyon Sarcoid Uveitis Cohort
Sarcoidosis is a systemic disease with unknown etiology. Chronicity of the disease is observed in 1/3 of cases. Five percent of the affected patients are expected to die due to pulmonary worsening.
- Trial name
- LUCS (NCT03863782)
- Testing
- No intervention
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Solid Malignancy Located in the Head and Neck, Cancer
Study of 68GaNOTA-Anti-MMR-VHH2 in Oncological Lesions, Cardiovascular Atherosclerosis, Syndrome With Abnormal Immune Activation and sarcoïdosis
Phase II study to evaluate the clinical potential of 68GaNOTA-anti-MMR-VHH2 for in vivo imaging of Macrophage Mannose Receptor (MMR)-expressing Macrophages by means of Positron Emission Tomography (PET) in patients with…
- Conditions
- Solid Malignancy Located in the Head and Neck, Cancer, Carotid Stenosis, Atherosclerosis of Artery
- Trial name
- MITRAS (NCT04758650)
- Testing
- 68GaNOTA-Anti-MMR-VHH2
- Where
- Belgium
- Volunteers
- 29 people
- Sponsor
- Universitair Ziekenhuis Brussel
Sarcoid-associated Uveitis, Ocular Sarcoidosis
Efficacy Study of Methotrexate to Treat Sarcoid-associated Uveitis
The purpose of this study is to determine whether methotrexate is a effective corticosteroid sparing agent in the treatment of sarcoid-associated uveitis.
- Conditions
- Sarcoid-associated Uveitis, Ocular Sarcoidosis, Macular Edema
- Trial name
- UVEXATE (NCT00918554)
- Testing
- Methotrexate
- Where
- 2 sites in France
- Volunteers
- 7 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiac Sarcoidosis
Non-Invasive Characterization in Cardiac Sarcoidosis
In a study of Cardiac sarcoidosis, a serious heart condition, a radiotracer is being used to examine inflammation.
- Trial name
- NCT02017522
- Testing
- 11C-PBR PET
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Michigan
Healthy Controls, Chronic Obstructive Pulmonary Disease
Number of Multiple Breath Washout Tests in Adults With Pulmonary Disease and Healthy Controls
The investigators aim to determine the optimal number of measurements required for multiple-breath-washout derived lung function parameters in adults with pulmonary disease as well as in healthy controls
- Conditions
- Healthy Controls, Chronic Obstructive Pulmonary Disease, Bronchial Asthma, Sarcoidosis
- Trial name
- NCT03176745
- Testing
- multiple breath washout
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
Lung Cancer, Sarcoidosis
Rapid On-site Cytopathologic Evaluation in the Diagnosis of Hilar/Mediastinal Adenopathy
The purpose of this study is to determine whether rapid on-site cytopathologic evaluation (ROSE) can increase the diagnostic yield of transbronchial needle aspiration (TBNA) in the diagnosis of hilar and mediastinal…
- Conditions
- Lung Cancer, Sarcoidosis, Tuberculosis
- Trial name
- NCT00915330
- Testing
- Rapid on-site cytopathologic evaluation (ROSE), TBNA
- Where
- Italy
- Volunteers
- 164 people
- Sponsor
- Maggiore Bellaria Hospital, Bologna
Peripheral Neuropathy, Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Clinical Trial to Assess the Safety of a Novel Scaffold Biomaterial
This is safety study. Subjects will be undergoing the surgical procedure of nerve biopsy. After routine surgery without grafting, patients develop swelling, redness, tenderness and dysesthesia at the biopsy site.
- Conditions
- Peripheral Neuropathy, Chronic Inflammatory Demyelinating Polyradiculoneuropathy, Vasculitic Neuropathy (Disorder), Amyloidosis
- Trial name
- NCT03584022
- Testing
- Biopsy + Nerve Repair, Biopsy Only
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Muscular Sarcoidosis
Effect of Fermented Oyster Extract on Musculoskeletal Biomarkers in Relative Sarcopenia Adults
The investigators conduct a randomized, double-blind, placebo-controlled study to investigate the effects of the fermented oyster extract on muscle strength, muscle mass, and muscle function in healthy adults for 12 weeks.
- Trial name
- NCT04109911
- Testing
- Fermented oyster extract
- Where
- South Korea
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Sarcoidosis, Pulmonary
A Study to Assess the Efficacy and Safety of Namilumab in Participants With Chronic Pulmonary Sarcoidosis
This is a randomized, double-blind, placebo-controlled study with an open-label extension (OLE).
- Trial name
- RESOLVE-Lung (NCT05314517)
- Testing
- Namilumab
- Where
- 47 sites in United States, Belgium and 5 more
- Volunteers
- 107 people
- Sponsor
- Kinevant Sciences GmbH
Cardiac Sarcoidosis, Myocardial Inflammation
18F-FSPG PET/MRI or PET/CT Imaging of Cardiac Sarcoidosis or Inflammation
The investigators will evaluate the detection of cardiac sarcoidosis or inflammation using 18F-FSPG PET/MRI (or PET/CT for participants with metal implants).
- Trial name
- NCT03103490
- Testing
- 18F-FSPG
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Stanford University
Sarcoidosis
Low-dose Dexamethasone in Newly Diagnosed Pulmonary Sarcoidosis
This trial examines whether low grade suppression of the initial inflammatory process of sarcoidosis by intervention with low-dose dexamethasone therapy achieves significant alleviation of (sub-)acute symptoms, improvement in…
- Trial name
- DEXSAR (NCT01920919)
- Testing
- Dexamethasone
- Where
- Netherlands
- Volunteers
- 76 people
- Sponsor
- St. Antonius Hospital
Lymphadenopathy, Lung Cancer
EBUS-TBNA vs Flex 19G EBUS-TBNA
Endobronchial ultrasound (EBUS) guided transbronchial needle aspiration (EBUS-TBNA) is an excellent tool for sampling enlarged mediastinal and hilar lymph nodes, but only provides needle aspirate samples which are often adequate…
- Conditions
- Lymphadenopathy, Lung Cancer, Sarcoidosis, Lymphoma
- Trial name
- NCT02592837
- Testing
- Flexible 19G EBUS-TBNA needle, 21G EBUS-TBNA needle
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Sarcoidosis
Minimally Invasive Techniques Or Surgery In the Diagnosis of Sarcoidosis
The purpose of this study is to evaluate the yield of endoscopic guided fine needle aspirations (by means of transoesophageal endoscopic ultrasound : EUS-FNA or transbronchial endoscopic ultrasound : EBUS-TBNA) in patients with a…
- Trial name
- MITOSIS (NCT00888212)
- Testing
- Bronchoscopy
- Where
- 15 sites in Belgium, Netherlands
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent