Clinical trials: SARCOIDOSIS
Sarcoidosis, Pulmonary
SARCOLOWDOSE : Ultra-low Dose CT Scan and MRI in Thoracic Sarcoidosis
The goal of this study is to evaluate the diagnostic agreement between, on the one hand, ultra-low dose CT and MRI with UTE pulse sequences, and on the other hand, standard CT scan, to quantify lung parenchyma patterns in…
- Trial name
- SARCOLOWDOSE (NCT03140644)
- Testing
- Patients with thoracic sarcoidosis
- Where
- 7 sites in France
- Volunteers
- 196 people
- Sponsor
- Rennes University Hospital
Sarcoidosis, Fatigue
Use of Armodafinil for Fatigue in Sarcoidosis
To determine the effect of Armodafinil (Nuvigil) on fatigue and sleep in sarcoidosis.
- Conditions
- Sarcoidosis, Fatigue, Sleepiness
- Trial name
- NCT00555347
- Testing
- Armodafinil
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Cincinnati
Interstitial Lung Disease
Pulmonary Care and Research Collaborative Patient Registry
The purpose of this research study is to build and maintain a registry of people with interstitial lung disease (ILD). Medical information collected for this registry may be used to advance ILD and pulmonary research and improve…
- Trial name
- NCT05445817
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Pulmonary Care and Research Collaborative Limited
Sarcoidosis, Cancer
Association Between Cancer and Sarcoidosis
The purpose of this study is to develop a clinical dataset of sarcoidosis patients with a diagnosis of cancer who are categorized by date of birth, sex, race/ethnicity, clinical information, laboratory and imaging information…
- Trial name
- NCT03844698
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- University of Miami
Mediastinal Lymphadenopathy, Hilar Lymphadenopathy
EBUS-TBNA Versus EBUS-TBNB
A prospective diagnostic clinical study randomising patients undergoing endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) of enlarged mediastinal and hilar lymph nodes to have sampling using the usual…
- Conditions
- Mediastinal Lymphadenopathy, Hilar Lymphadenopathy, Carcinoma, Lymphoma
- Trial name
- NCT01467635
- Testing
- Endobronchial ultrasound guided lymph node sampling
- Where
- 3 sites in Germany, United Kingdom
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Cardiac Sarcoidosis
Biomaterial Collection - and Analysis in Cardiac Sarcoidosis
Cardiac sarcoidosis (CS) is a complex disease that is characterized by the formation of inflammatory granulomas in the myocardium.
- Trial name
- NCT05793398
- Volunteers
- 100 people
- Sponsor
- Heart Center Leipzig - University Hospital
Cystic Fibrosis, Pulmonary Fibrosis
Role of Genetic Factors in the Development of Lung Disease
This study is designed to evaluate the genetics involved in the development of lung disease by surveying genes involved in the process of breathing and examining the genes in lung cells of patients with lung disease.
- Conditions
- Cystic Fibrosis, Pulmonary Fibrosis, Tuberous Sclerosis, Asthma
- Trial name
- NCT00001532
- Where
- 2 sites in United States
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Interstitial Lung Diseases, Sarcoidosis
The Occurence of Inflammation and Oxidative Stress in Lung Diseases
Reactive oxygen species (ROS) are suggested to play a pivotal role in ILD. Little is known, however, about the endogenous antioxidant levels in ILD that can offer protection against ROS.
- Conditions
- Interstitial Lung Diseases, Sarcoidosis, Idiopathic Pulmonary Fibrosis, COPD
- Trial name
- NCT00512967
- Where
- Netherlands
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Sarcoidosis
A Trial to Compare Two Methods of Obtaining Tissue for Diagnosis of Sarcoidosis Namely the Conventional Method or the Ultrasound Guided Method
This trial compares the yield of cTBNA (conventional Transbronchial Needle Aspiration) versus the EBUS-TBNA (Endobronchial Ultrasound guided TBNA) for obtaining cytology when they are combined with endobronchial biopsy and…
- Trial name
- NCT02472808
- Testing
- cTBNA without ROSE, cTBNA with ROSE, EBUS-TBNA without ROSE
- Where
- India
- Volunteers
- 80 people
- Sponsor
- All India Institute of Medical Sciences
Sarcoidosis, Cutaneous Sarcoidosis
The Efficacy and Safety of CC-10004 in Chronic Cutaneous Sarcoidosis
To determine whether CC-10004, a phosphodiesterase inhibitor, is useful in treating chronic cutaneous sarcoidosis.
- Trial name
- NCT00794274
- Testing
- CC-100004
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Cincinnati
Sjögren's Syndrome
Evaluation of the Efficacy and the Mechanism of Chinese Herbal Formula SS-1 for Sjögren's Syndrome
To evaluate the efficacy of Chinese herbal medicine (SS-1) for the Sjögren's syndrome (SJS) patients.
- Trial name
- SS-1 (NCT02110446)
- Testing
- SS-1
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Sarcoidosis
Exercise Training in Sarcoidosis (EXTRAS Study)
Exercise intolerance and reduced health status have been found in patients with sarcoidosis and has been related to skeletal muscle weakness.
- Trial name
- NCT00099424
- Testing
- High-intensity exercise training
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Gasthuisberg
Lymphadenopathy, Tuberculosis
Diagnostic Accuracy of Polymerase Chain Reaction for Mycobacterium Tuberculosis Using EBUS-TBNA Samples
The purpose of this study is to compare the diagnostic efficacy of nested and realtime polymerase chain reaction for Mycobacterium tuberculosis using EBUS-TBNA samples in patients with isolated intrathoracic lymphadenopathy.
- Conditions
- Lymphadenopathy, Tuberculosis, Sarcoidosis
- Trial name
- NCT02497079
- Testing
- Nested PCR for formalin-fixed tissues, Nested PCR for fresh tissues, Real-time PCR for fresh tissues
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Pusan National University Hospital
Acute Cellular Graft Rejection, Cardiac Sarcoidosis
[68Ga]Ga-PentixaFor PET/CT in Acute Myocardial Inflammation
Acute myocardial inflammation is an heterogenic syndrome involving different clinical pathologies with different outcome. For the purpose of this study protocol, we focuse on three entities of this syndrome, namely the acute…
- Conditions
- Acute Cellular Graft Rejection, Cardiac Sarcoidosis, Myocarditis Due to Drug
- Trial name
- NCT05499637
- Testing
- [68Ga]Ga-PentixaFor PET/CT
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- John O. Prior
Cervical Cancer, Fallopian Tube Cancer
Immunotoxin Therapy in Treating Patients With Advanced Cancer
RATIONALE: Immunotoxins can locate tumor cells and kill them without harming normal cells. Immunotoxin therapy may be an effective treatment for advanced cancer.
- Conditions
- Cervical Cancer, Fallopian Tube Cancer, Head and Neck Cancer, Lung Cancer
- Trial name
- NCT00006981
- Testing
- SS1(dsFv)-PE38 immunotoxin
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)
Uveitis
Uveitis/Intraocular Inflammatory Disease Biobank (iBank)
Background: Uveitis is a serious eye disease that can cause vision loss. Treatment sometimes causes serious side effects or does not work. Researchers want to learn more about uveitis and why some people develop it.
- Trial name
- NCT02656381
- Where
- United States
- Volunteers
- 343 people
- Sponsor
- National Eye Institute (NEI)
Sarcoidosis
Testing Hypersensitivity to Metals in Sarcoidosis Patients by Applying the MELISA Test.
The purpose of this study is to apply the MELISA test, that diagnose hypersensitivity to metals, in Sarcoidosis patients with occupational exposure.
- Trial name
- NCT01809145
- Testing
- MELISA test
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pulmonary Sarcoidosis
Randomized Controlled Trial of Hydroxychloroquine Combined With Low-dose Corticosteroid in Pulmonary Sarcoidosis
"The reference treatment for pulmonary sarcoidosis is prolonged systemic corticosteroid therapy, which improves dyspnea, fatigue and respiratory function.
- Trial name
- QUIDOSE (NCT05247554)
- Testing
- Hydroxychloroquine + low-dose prednisone, Prednisone
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sarcoidosis
RCT Comparing 21 and 22 G Needle in the Diagnosis of Sarcoidosis by EBUS TBNA
Randomized controlled trial to determine the efficacy of different needles sizes (22G and 21G) used in endobronchial ultrasound guided transbronchial needle aspiration
- Trial name
- NCT02459431
- Testing
- 21 G needle group, 22 G needle group
- Where
- India
- Volunteers
- 151 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Cardiac Sarcoidosis
PET/MR Imaging In Patients With Cardiac Sarcoidosis
PET scanning (positron emission tomography) is a well-established technique used to identify areas of interest within the body. It involves injecting a radioactive tracer which highlights abnormal areas.
- Trial name
- NCT03705884
- Testing
- 18F-FDG, Prednisolone
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh