Clinical trials: SARCOIDOSIS
Sarcoidosis
The Effect of Quercetin in Sarcoidosis
The exact cause of the chronic lung disease sarcoidosis is still unknown. Consequently, a complete efficacious treatment is still not available. Earlier studies indicate an important key role for oxidative stress, i.e.
- Trial name
- NCT00402623
- Testing
- quercetin
- Where
- Netherlands
- Volunteers
- 18 people
- Sponsor
- Maastricht University Medical Center
Danon Disease, Fabry Disease
Precision Diagnosis and Risk Stratification of Rare Cardiomyopathies Based on Novel Cardiac Magnetic Resonance Techniques
What is this study about? This research is focused on improving the care for people with rare heart muscle diseases, known as rare cardiomyopathies.
- Conditions
- Danon Disease, Fabry Disease, Cardiac Amyloidosis, Noonan Syndrome
- Trial name
- NCT07336394
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Sarcoidosis, Uveitis
Eye and Immunogenetic Features of Sarcoidosis
This study will evaluate patients with sarcoidosis to understand how the disease affects the body. Sarcoidosis is a disease that results from inflammation of body tissues.
- Trial name
- NCT00379275
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Eye Institute (NEI)
Sarcoidosis
Effect of the Number of Needle Revolutions Inside the Node on the Diagnostic Yield of EBUS-TBNA in Sarcoidosis
The investigators plan to evaluate the effect of the number of needle revolutions inside the node on the diagnostic yield of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in patients with…
- Trial name
- NCT02875756
- Testing
- 10 revolutions, 20 revolutions
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Sarcoid-associated Uveitis, Ocular Sarcoidosis
Efficacy Study of Methotrexate to Treat Sarcoid-associated Uveitis
The purpose of this study is to determine whether methotrexate is a effective corticosteroid sparing agent in the treatment of sarcoid-associated uveitis.
- Conditions
- Sarcoid-associated Uveitis, Ocular Sarcoidosis, Macular Edema
- Trial name
- UVEXATE (NCT00918554)
- Testing
- Methotrexate
- Where
- 2 sites in France
- Volunteers
- 7 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pulmonary Fibrosis, Sarcoidosis
Fibrosing ILD Biomarkers That Rule Acceleration
FIBRALUNG is a prospective cohort study with biobank of samples from patients with pulmonary fibrosis, aiming to explore the molecular determinants of different clinical outcomes, acute exacerbations and mortality.
- Trial name
- FIBRALUNG (NCT05635032)
- Testing
- Comprehensive clinical assessment and biological samples collection
- Where
- Portugal
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Sarcoidosis
Prognostic Value of Clinical Cardiovascular MRI
The primary objective of this study is to identify findings on cardiovascular MR imaging (CMR) that are specific to various cardiac or vascular disorders in patients undergoing routine CMR scans.
- Trial name
- NCT01745237
- Where
- United States
- Volunteers
- 27,000 people
- Sponsor
- Duke University
Sarcoidosis
Genomic Research in Sarcoidosis
This project is designed to address the following hypothesis: Distinct patterns in lung microbiome are characteristic of sarcoidosis phenotypes and reflected in changes in systemic inflammatory responses as measured by peripheral…
- Trial name
- GRADS Sarc (NCT01831739)
- Where
- 9 sites in United States
- Volunteers
- 368 people
- Sponsor
- University of Pittsburgh
Sarcoidosis
Perfusion Analysis Using Rubidium in Cardiac Sarcoidosis
The study aims at assessing diagnostic and therapeutic impact of Rubidium-82 PET in cardiac sarcoidosis.
- Trial name
- PARCS (NCT01648933)
- Testing
- Rubidium PET
- Where
- France
- Volunteers
- 53 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Interstitial Lung Disease
Pulmonary Care and Research Collaborative Patient Registry
The purpose of this research study is to build and maintain a registry of people with interstitial lung disease (ILD). Medical information collected for this registry may be used to advance ILD and pulmonary research and improve…
- Trial name
- NCT05445817
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Pulmonary Care and Research Collaborative Limited
Sarcoidosis, Pulmonary, Sarcoidosis Skin
the PHENOSAR Trial: Use of Antibiotics in Treatment of Sarcoidosis
In this study it is investigated whether treatment with azithromycin in combination with doxycycline reduces the bacterial load of C.
- Trial name
- NCT05291468
- Testing
- FDG-PET/CT
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- St. Antonius Hospital
Asthma, Chronic Obstructive Pulmonary Disease
Exploring the Utility of Hyperpolarized 129Xe MRI in Healthy Volunteers and Patients With Lung Disease
This is a single centre exploratory study that aims to apply hyperpolarized xenon-129 (129Xe) magnetic resonance imaging (MRI) methods and measurements in individual patients with and without lung disease to better understand…
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease, Bronchiectasis, Emphysema
- Trial name
- NCT03455686
- Testing
- Hyperpolarized 129Xe MRI
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- McMaster University
Lung Cancer, Sarcoidosis
Full-Field Optical Coherence Tomography (FFOCT) for Evaluation of Bronchoscopic Small Biopsy Specimens
This study sets out to register imaging of small biopsy specimens obtained during bronchoscopy using full-field optical coherence tomography against standard histologic evaluation.
- Trial name
- NCT05171478
- Testing
- Full-field optical coherence tomography
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Sarcoidosis, Fatigue
SPARC Smartphone Application for the Management of Sarcoidosis-Associated Fatigue
Fatigue is a pervasive and disabling symptom in sarcoidosis with limited treatment options. There is a significant association between heightened stress and sarcoidosis-associated fatigue.
- Trial name
- SPARC (NCT05230693)
- Testing
- Sarcoidosis Patient Assessment and Resource Companion App, Enhanced Standard Care
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Medical University of South Carolina
Neuropathy of Sarcoidosis
Study of Efficacy of ARA 290 on Corneal Nerve Fiber Density and Neuropathic Symptoms of Subjects With Sarcoidosis
The purpose of this study is to determine whether ARA 290, a new class of compound, is effective in the treatment of the neuropathic symptoms of sarcoidosis.
- Trial name
- NCT02039687
- Testing
- ARA 290
- Where
- 2 sites in United States, Netherlands
- Volunteers
- 64 people
- Sponsor
- Araim Pharmaceuticals, Inc.
Sarcoidosis
Hematopoietic Stem Cell Support in Patients With Refractory Sarcoidosis
Sarcoidosis is a disease believed to be due to immune cells, cells which normally protect the body, but are now attacking lungs, heart, nerves, or other organs or systems within the body.
- Trial name
- NCT00282438
- Testing
- Autologous hematopoietic stem cell transplantation, Allogeneic stem cell transplantation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Northwestern University
Sarcoidosis
Comparison of Characteristics of Bronchoalveolar Lavage Dusting and of Specific Questionnary Data in Healthy Volunteers and Patients Suffering From Sarcoidosis
Comparison of dusting rate of bronchoalveolar lavage in healthy volunteers and patients suffering from sarcoidosis. Blind analysis of bronchoalveolar lavage with Optical Microscopy, Transmission Electron Microscopy and…
- Trial name
- MINASARC01 (NCT02863406)
- Testing
- Bronchoalveolar lavage
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Saint Joseph Saint Luc de Lyon
Sarcoidosis
A Study of Adalimumab to Treat Sarcoidosis of the Skin
The purpose of this study is to determine if adalimumab is an effective for the skin manifestations of sarcoidosis.
- Trial name
- NCT00274352
- Testing
- adalimumab
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Pariser, Robert J., M.D.
Sarcoidosis, Rickettsia Infections
Rickettsial Genesis to Sarcoidosis in Denmark
One study has suggested a connection between an infection with Rickettsia species and sarcoidosis finding molecular evidence of rickettsial deoxyribonucleic acid (DNA) in two patients.
- Trial name
- NCT00326534
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- Statens Serum Institut
Pulmonary Healthy Controls, Interstitial Lung Disease
Evaluation of Novel Lung Function Parameters in Patients With Interstitial Lung Disease (ILD)
Current diagnostic tools used in interstitial lung disease (ILD) do not meet the challenges set by the complex pathophysiology of this heterogenous group.
- Conditions
- Pulmonary Healthy Controls, Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis, Non-specific Interstitial Pneumonia
- Trial name
- NCT02827734
- Testing
- multiple breath washout tests, impulse oscillometry, body plethysmography
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim