Clinical trials: SARS-COV-2 Infections
Covid19
A Study of Inhaled Ampion in Adults With Respiratory Distress Due to COVID-19
This is phase II study to evaluate the safety and efficacy of inhaled Ampion in adults with respiratory distress due to COVID-19
- Trial name
- NCT04868890
- Testing
- Ampion
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Ampio Pharmaceuticals. Inc.
Sars-CoV2, Severe Neurologic Injury
COVID-19 Brain Injury
A prospective cohort minimal risk study to determine the impact of the COVID-19 crisis on outcomes of neurologically injured ICU patients.
- Conditions
- Sars-CoV2, Severe Neurologic Injury, Ischemic Stroke, Hemorrhagic Stroke
- Trial name
- NCT04496076
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Pittsburgh
COVID19
Study to Evaluate the Safety and Efficacy of VIRAZOLE® in Hospitalized Adult Participants With Respiratory Distress Due to COVID-19
This study is a Phase 1, open label, non-randomized, two-arm interventional clinical trial to evaluate the safety and efficacy of Virazole® in hospitalized adult patients who have tested positive for COVID-19 and, as a result…
- Trial name
- NCT04551768
- Testing
- 50 mg/mL Virazole, 100 mg/mL Virazole
- Where
- 4 sites in Greece, Mexico
- Volunteers
- 51 people
- Sponsor
- Bausch Health Americas, Inc.
Coronavirus Disease 2019, Novel Coronavirus Pneumonia
The Effect of T89 on Improving Oxygen Saturation and Clinical Symptoms in Patients With COVID-19
This is an open-label, randomized, blank-controlled treatment clinical study. The objective of this study is to investigate the effect of T89 on improving oxygen saturation and clinical symptoms in patients with Coronavirus…
- Trial name
- NCT04285190
- Testing
- T89
- Sponsor
- Tasly Pharmaceuticals, Inc.
Long Covid19
Diaphragm Dysfunction After COVID-19 as Determined by Dynamic Chest Radiography
Dynamic chest radiography (DCR) is a rapid and easily performed technique that captures real-time continuous images of the moving chest.
- Trial name
- DD-COVID-19 (NCT06175455)
- Testing
- dynamic chest radiography
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Covid19
A Pilot Study for the Collection Of Vocalized, Individual Digital Cough Sound Recordings to Screen for COVID-19
Decentralized clinical study designed to collect cough sounds and self-reported symptoms alongside a COVID-19 realtime quantitative polymerase chain reaction (rt-qPCR) test.
- Trial name
- COVID-Cough (NCT04864535)
- Testing
- Recordings of cough sounds from adults
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- ResApp Health Limited
COVID-19
COVID-19 Lessons Learned: the Outcome of TOMEKA® Project is to Teach
Living in Canada and being health-worker in the first line face to COVID-19, investigator outcome is to teach an experience or explain the disease using a review and get people prepared to COVID-19 treatment focused on adherence…
- Trial name
- MD (NCT04424940)
- Where
- Democratic Republic of the Congo
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Kinshasa
COVID-19, Mental Health
Impact of a Minimal Psychoeducational Intervention on Anxiety Among Hospitalized COVID-19 Patients in Denmark
Background: There is limited knowledge on the psychological implications of COVID-19 among hospitalized patients and their close relatives.
- Conditions
- COVID-19, Mental Health, Psychoeducation, Anxiety
- Trial name
- PISCA (NCT04351789)
- Testing
- Psychoeducational intervention
- Where
- Denmark
- Volunteers
- 66 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Healthy Participants, Intrusive Memories
Understanding Reactions to Emotional Material in the Media During COVID-19
This feasibility study aims to adapt a protocol usually run in the laboratory in the Psychology Department for healthy participants (including the trauma film paradigm (James et al., 2016) and a simple cognitive task…
- Trial name
- NCT04608097
- Testing
- Simple cognitive task intervention
- Where
- Sweden
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Covid19
Reliability of Standardized Protocol of Ultrasound of the Lungs in Prediction of Severity of Covid-19 Infection
Ultrasound can reliably detect morphologic changes associated with pneumonia. Additionally, protocols were elaborated which unify the investigation procedure and improve the intra- and interrater reliability.
- Trial name
- NCT04513210
- Where
- Poland
- Volunteers
- 94 people
- Sponsor
- Jagiellonian University
Determine Effect of Urological Malpractice During Covid 19 on Patient Complications
The Impact of Covid 19 Pandemic on Ureteric Stents Complications.
The pandemic of coronavirus disease 2019 (COVID-19) has serious implications on urology practice and raises particular questions for urologists about the management of different conditions.
- Trial name
- NCT05839249
- Testing
- JJ urological stents
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- South Valley University
Long COVID
Inspiratory Muscle Training in People With Long COVID-19- A Pilot Investigation.
This pilot investigation will recruit people with Long COVID to participate in a 4 week individualized inspiratory muscle training intervention with pre and post spirometry testing and additional functional outcomes to assess the…
- Trial name
- NCT06091358
- Testing
- PrO2
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- University of Bath
Coronavirus Disease 2019, Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2
Study of Varespladib in Patients Hospitalized With Severe COVID-19
This is a 2-part, multi-center, randomized, double-blind, placebo-controlled, phase 2 study designed to evaluate the safety, tolerability, and efficacy of oral varespladib, in addition to standard of care, in patients…
- Trial name
- STAIRS (NCT04969991)
- Testing
- Varespladib
- Where
- 7 sites in United States
- Volunteers
- 18 people
- Sponsor
- Ophirex, Inc.
COVID-19
Brain Function Changes Following COVID-19 Infection
The global COVID-19 pandemic has now led to millions of infections worldwide. It produces long-lasting changes in the general physiology of multiple organs, including the brain.
- Trial name
- NCT05961618
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Coronavirus, COVID-19
TARGet Kids! COVID-19 Study of Children and Families
The novel coronavirus (COVID-19) was declared a global pandemic in March 2020. Early research suggests that children are no more susceptible to COVID-19 infection than adults and that children with confirmed COVID-19 have…
- Conditions
- Coronavirus, COVID-19, Virus, Family and Household
- Trial name
- NCT04449978
- Where
- 2 sites in Canada
- Volunteers
- 1,145 people
- Sponsor
- The Hospital for Sick Children
COVID-19
Non Invasive Positive Pressure Ventilation to Minimize Aerosolization for COVID 19
Patients presenting to the emergency department, or needing hospitalization, for a variety of medical conditions often require non-invasive ventilation (breathing support).
- Trial name
- NCT04344925
- Testing
- Aerosol-reducing Mask, Standard Mask
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Immunocompromised Patients
Immunocompromised Swiss Cohorts Based Trial Platform
This study is to set up a flexible trial platform using two existing national cohorts of immunocompromised patients (i.e. Swiss HIV Cohort Study [SHCS] and Swiss Transplant Cohort Study [STCS]) to assess the comparative…
- Trial name
- COVERALL (NCT04805125)
- Testing
- Moderna COVID-19 Vaccine, mRNA-1273 (100 μg), Pfizer-BioNTech COVID-19 Vaccine BNT162b2 (30 µg)( Comirnaty®)
- Where
- 4 sites in Switzerland
- Volunteers
- 610 people
- Sponsor
- University Hospital, Basel, Switzerland
Childhood Obesity
Evaluation of an Online Lifestyle Intervention in Mexican School Children During COVID-19 Pandemic
Introduction: School closures due to the COVID-19 pandemic represent a risk factor for the development of childhood obesity due to the increase in unhealthy behaviors.
- Trial name
- NCT04772859
- Testing
- Online Lifestyle Intervention, Control Group
- Where
- Mexico
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universidad de Sonora
COVID-19 Pneumonia
Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of CKD-314
A Double-blind, Multi-center, Multi-regional, Randomized controlled, Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of CKD-314 in Hospitalized Adult Patients Diagnosed with COVID-19
- Trial name
- NCT04871646
- Testing
- CKD-314+SOC
- Where
- South Korea
- Volunteers
- 586 people
- Sponsor
- Chong Kun Dang Pharmaceutical
COVID-19
A Safety and Immunogenicity Study of Inactivated SARS-CoV-2 Vaccine (Vero Cells) in Healthy Population Aged 18 Years and Above(COVID-19)
This study is a randomized, double-blinded, and placebo controlled phase Ⅰ clinical trial of the SARS-CoV-2 inactivated vaccine to evaluate the safety and immunogenicity of the experimental vaccine in healthy adults ⩾18 years.
- Trial name
- NCT04758273
- Testing
- medium dosage inactivated SARS-CoV-2 vaccine, high dosage inactivated SARS-CoV-2 vaccine
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Beijing Minhai Biotechnology Co., Ltd
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