Clinical trials: SARS-CoV-2 Infection Covid19
SARS-CoV2 Infection, COVID-19, Gut Microbiota, Mucosal Response, Children
COVID-19 and Intestinal Microbiota in Children
SARS-CoV-2 is the causative agent of the COVID-19 pandemic. It appears to cause only mild to moderate upper respiratory symptoms in children, in addition to gastrointestinal symptoms resulting from its penetration into intestinal…
- Trial name
- NCT06503887
- Testing
- Stool sample collection
- Where
- Lebanon
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Acute Respiratory Distress Syndrome
Clinical, Biological and Histological Pulmonary and Renal Damage Associated With the SARS-CoV-2 Syndrome in Patients Admitted in ICU
Renal damage in patients hospitalized for ARDS in the ICU can also be related to multiple causes including, but not limited to, the consequences of hemodynamic fluctuations in these patients or the use of nephrotoxic drugs…
- Trial name
- PR-Covid-19 (NCT04385004)
- Where
- France
- Volunteers
- 320 people
- Sponsor
- University Hospital, Strasbourg, France
Sickle Cell Disease, COVID-19
COVID-19 Vaccine Response in Sickle Cell Disease
The purpose of this study is to assess the antibody response to COVID-19 vaccination in a cohort of patients with sickle cell disease (SCD) and to assess vaccine and SCD related complications around the time of vaccination.
- Trial name
- NCT05139992
- Testing
- COVID-19 Vaccine
- Where
- 8 sites in United States
- Volunteers
- 59 people
- Sponsor
- ASH Research Collaborative
Adult Patients With Lesions on Fingers or Toes
Clinical and Mechanistic Study of Patients (With COVID-19 or Not) With a Recent Acrosyndrome
The recent and unexpected occurrence of patients with the development of skin lesions on the hands and/ or feet has been described recently.
- Trial name
- ACROCOVID (NCT04590209)
- Testing
- Blood sampling, Skin biopsy
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Healthy Volunteers
Safety and Immunogenicity of AdCOVID in Healthy Adults (COVID-19 Vaccine Study)
A study to evaluate the immune response and safety of AdCOVID administered as an intranasal spray in healthy adults.
- Trial name
- NCT04679909
- Testing
- AdCOVID
- Where
- 6 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Altimmune, Inc.
COVID-19, Children
Inhaled Interferon α2b Treatment in Mild-to-moderate COVID-19 Infected Children
In the COVID-19 pandemic era, a convenient and effective treatment for pediatric patients is unavailable. A multi-center Chinese clinical trials with the aim to using Interferon-α2b spray inhalation to develop new treatment…
- Trial name
- NCT05381363
- Testing
- Inhaled Interferon α2b, Standard of Care
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Children's Hospital of Fudan University
Stress
Yoga in NHS Health Care Workers With COVID-19 Related Stress
Recent reports have highlighted Covid-19 related increase in levels of depression and stress related disorders in the health care professionals.
- Trial name
- NCT04481516
- Testing
- Yoga
- Where
- United Kingdom
- Sponsor
- Doncaster And Bassetlaw Hospitals NHS Foundation Trust
COVID-19 Vaccines
Study to Evaluate the Immunogenicity and Safety of Heterologous SARS-CoV-2 Vaccine Schemes
To determine whether a heterologous vaccination regimen in individuals with no known previous history of COVID-19 is non-inferior to that observed with counterpart regimens currently in use in Argentina.
- Trial name
- NCT04962906
- Testing
- Gam-COVID-Vac / Gam-COVID-Vac
- Where
- Argentina
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Ministerio de Salud de Ciudad Autónoma de Buenos Aires
Cognitive Training, Transcranial Direct Current Stimulation
Brain Research and Integrative Neuroscience Network for COVID-19
The aim of the experimental study is to investigate two interventions for the management of cognitive symptoms resulting from long COVID. Participants will be randomly assigned into two interventions. 1.
- Trial name
- BRAINN (NCT06517706)
- Testing
- Combination of tDCS (device) with cognitive training (behavioral), Categorization Program
- Where
- Cyprus
- Volunteers
- 38 people
- Sponsor
- University of Cyprus
Vaccine-Preventable Diseases, Vaccine Refusal
Volatility and Heterogeneity of Vaccine Sentiments Means Continuous Monitoring is Needed When Measuring Message Effectiveness
The success of vaccination programs often depends on the effectiveness of the vaccine messages, particularly during emergencies such as the COVID-19 pandemic.
- Trial name
- NCT05499299
- Testing
- Google ads
- Where
- Hong Kong
- Volunteers
- 127,000 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
COVID-19
Community Perception on COVID-19 Prevention and Control
In times whereby COVID-19 is rapidly spreading, research on the epidemiological, diagnostic, clinical and social aspects of the illness has been highlighted as important as there is very limited information of this disease in all…
- Trial name
- NCT06452108
- Where
- Pakistan
- Volunteers
- 2,651 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Covid-19 Immune Status of Healthcare Workers
Rapid Screening Test for Covid-19 Antibodies in Healthcare Workers
The study objectives were to assess 1/the immune status of healthcare professionals with suggestive symptomatology of Covid-19 infection and 2/the sensitivity and specificity of AAZ rapid test by comparing it with a serological…
- Trial name
- NCT04525417
- Testing
- AAZ Covid-19 rapid test
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Groupe d'Etude sur le Risque d'Exposition des Soignants aux Agents Infectieux
Covid-19, Pneumonia
The Effects of Pulmonary Physiotherapy Treatments on Patients With COVID-19
The aim of this study is to evaluate the efficacy of pulmonary physiotherapy on respiratory functions in hospitalized patients with Novel Coronavirus 2019 pneumonia.
- Conditions
- Covid-19, Pneumonia, SARS Pneumonia
- Trial name
- NCT04357340
- Testing
- Pulmonary Physiotherapy Techniques
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Tehran University of Medical Sciences
COVID-19
To Evaluate the Immunogenicity and Safety of Sequential Booster Immunization of Recombinant Novel Coronavirus Vaccine (CHO Cells) for SARS-CoV-2
An open experimental design was used in this study, and 240 subjects were planned to be enrolled. To evaluate the immunogenicity and safety of recombinant Novel Coronavirus vaccine (CHO cells) after sequential intensification in…
- Trial name
- NCT05895110
- Testing
- Recombinant Novel Coronavirus vaccine (CHO Cells)
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Covid19
Use of Inhaled High-molecular Weight Hyaluronan in Patients With Severe COVID19: Feasibility and Outcomes
To determine whether inhaled Yabro protects against progression of COVID19-induced respiratory failure preventing the passage to non-invasive ventilation (NIV) and promotes recovery from COVID19 lung disease in hospitalized…
- Trial name
- HA-COVID (NCT04830020)
- Testing
- HMW-HA
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Campus Bio-Medico University
COVID-19 Disease
Epidemiologic Register on Diabetes and COVID-19 in Tunisia
CoviDTUN is a multicenter observatory set up by a steering committee to determine the presentation and evolution of diabetes in COVID-19 and study its pathogenesis.
- Trial name
- NCT05603130
- Testing
- routinely collected clinical information
- Where
- Tunisia
- Volunteers
- 811 people
- Sponsor
- Les Laboratoires des Médicaments Stériles
COVID-19
Provide Pre-approval Single-patient Expanded Access (Compassionate Use) of VYD222 for Patients With Symptomatic COVID-19 Refractory to Other Treatments
Provide pre-approval single-patient Expanded Access (Compassionate Use) of VYD222 for patients with symptomatic COVID-19 refractory to other treatments.
- Trial name
- NCT06004128
- Testing
- VYD222
- Sponsor
- Invivyd, Inc.
Covid19
Artificial Intelligence - SARS-CoV-2 (COVID-19) Risk Evaluation
The management of COVID-19 patients in overwhelmed hospital facing the pandemic is a clinical challenge. The improvement of decision making may allow a better allocation of available resources and a better treatment of patients…
- Trial name
- AI-SCoRE (NCT04834934)
- Where
- Italy
- Volunteers
- 2,000 people
- Sponsor
- IRCCS San Raffaele
Covid19, Stress, Psychological
Psychological Impact of COVID-19 Pandemic in Healthcare Workers
Background. The current coronavirus disease (COVID-19) has a great impact worldwide. Healthcare workers play an essential role and are one of the most exposed groups.Information about the psychosocial impact on healthcare workers…
- Conditions
- Covid19, Stress, Psychological, Work Related Stress, Epidemic Disease
- Trial name
- PSIMCOV (NCT04506515)
- Testing
- Psychological stress and adaptation at work score (PSAS)
- Where
- Spain
- Volunteers
- 3,000 people
- Sponsor
- Hospital General Universitario de Valencia
Covid-19
A Study in Patients With COVID-19 and Respiratory Distress Not Requiring Mechanical Ventilation, to Compare Standard-of-care With Anakinra and Tocilizumab Treatment The Immunomodulation-CoV Assessment (ImmCoVA) Study
The study is designed as a randomized, controlled, multi-center open-label trial to compare standard-of-care (SOC) treatment with SOC + anakinra or SOC + tocilizumab treatment in hospitalized adult subjects who are diagnosed with…
- Trial name
- NCT04412291
- Testing
- Anakinra Prefilled Syringe, Tocilizumab Prefilled Syringe, Standard-of-care treatment
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Karolinska University Hospital
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