Clinical trials: SARS-CoV-2 Infections
Ventilation During Resuscitation
Mouth-to-mouth Ventilation Efficiency Through Breathable Self-sterilizing Respirator During BLS in COVID-19 Pandemic
Complex practical BLS training have been stopped all over the world due to COVID-19 pandemic in 2020. While launching the new Simulation Centre at Medical Faculty of Masaryk University in Brno, Czech Republic, teachers and…
- Trial name
- MOVERESP (NCT04867265)
- Testing
- Mout-to-mouth ventilation, Mout-to-mouth ventilation with quantitative analysis
- Where
- Czechia
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Brno University Hospital
Depression, Generalized Anxiety
The Mental Health Status of the General Population During the COVID-19 Pandemic and Its Association With Adherence to Government-initiated Non-pharmacological Epidemiological Interventions (NPI's)
This study seeks to investigate the levels of common psychopathology symptoms (i.e., depression and generalized anxiety) in a general population during the strict social distancing government-initiated non-pharmacological…
- Conditions
- Depression, Generalized Anxiety, Adherence to Non-pharmacological Epidemiological Interventions (NPIs)
- Trial name
- NCT04356365
- Testing
- Cross-sectional study investigating the association of NPIs with mental health
- Where
- Norway
- Volunteers
- 10,084 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Birth Outcomes, Safety
Simultaneous mRNA COVID-19 and IIV Vaccination in Pregnancy Study
This study is a prospective, randomized clinical trial. During this study, pregnant women will be randomly assigned to receive IIV and mRNA COVID-19 vaccine either simultaneously or sequentially (7-14 days apart).
- Conditions
- Birth Outcomes, Safety, Adverse Event Following Immunization
- Trial name
- NCT06503900
- Testing
- mRNA COVID-19 vaccine, IIV4 (quadrivalent inactivated influenza vaccine)
- Where
- 6 sites in United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Duke University
HIV Infections, Covid19
Bidirectional, Upbeat Communication and Differentiated, Distanced Care for Young People
Sub Saharan Africa is home to only 12% of the population, but accounts for approximately 70% of the global burden of HIV infection and 84% of infections among young people aged 10-24 years.
- Conditions
- HIV Infections, Covid19, Health Care Utilization, Gender-based Violence
- Trial name
- BUDDY (NCT04781400)
- Testing
- Mobile phone support, Remote service delivery model
- Where
- South Africa
- Volunteers
- 536 people, healthy volunteers welcome
- Sponsor
- Desmond Tutu HIV Foundation
Reactive Axillary Lymphadenopathy for SARS-CoV-2 Vaccines in the Asian Taiwanese Population
Sonography for COVID-19 Vaccines Related Reactive Lymphadenopathy
This study aimed to provide vast clinical information to facilitate breast sonographic examination for participants who underwent recent SARS-CoV-2 vaccination.
- Trial name
- NCT06429020
- Testing
- the AstraZeneca ChAdOx1 (AZ) vaccine, Moderna mRNA-1273 (Moderna) vaccine, and Pfizer-BioNTech BNT162b2 (BNT) vaccine.
- Where
- Taiwan
- Volunteers
- 1,089 people, healthy volunteers welcome
- Sponsor
- Chimei Medical Center
COVID-19
Open-label, Non-randomized, Non-comparative, Phase II Study of Safety and Immunogenicity of Combination of AZD1222 and rAd26-S for COVID-19 Prevention
The purpose of the study is to assess safety and immunogenicity of heterologous booster vaccine containing combination of AZD1222 and rAd26-S (one of components of Gam-COVID-Vac vaccine) in adult subjects aged ≥ 18 years old to…
- Trial name
- NCT04686773
- Testing
- AZD1222, rAd26-S
- Where
- Azerbaijan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- R-Pharm
COVID-19, Sars-CoV-2 Infection
Efficacy and Safety of NVX-CoV2705
This is a Phase 4, post-market US study, evaluating the efficacy and safety of a single dose of the NVX-CoV2705 Omicron JN.1 COVID-19 vaccine.
- Trial name
- COVID-19 (NCT07086222)
- Testing
- NVX-CoV2705
- Where
- 99 sites in United States
- Volunteers
- 6,500 people, healthy volunteers welcome
- Sponsor
- Novavax
Anosmia
Investigating the Efficacy of OMT to Recover Olfactory Perception After COVID-19
One of the most widespread symptoms of COVID-19 is loss of the sense of smell. There are very few treatments for helping individuals recover their sense of smell.
- Trial name
- NCT06766279
- Testing
- Osteopathic Manipulative Treatment
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Burrell College of Health Sciences
COVID-19
Detection of COVID-19 Subjects Using DiaNose Exhalation Test
The study aim is to collect and analyze data of potential Volatile Organic Compounds (VOCs) that could be used for discriminating between patients with and without COVID-19 or with high-risk for COVID-19 by DiaNose breath test.
- Trial name
- NCT04476927
- Testing
- DiaNose
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Nanose Medical Ltd.
In Utero SARS-CoV-2 Exposure
In Utero Exposure to SARS-CoV-2 (COVID-19) and Cardiovascular and Metabolic Endpoints in Early Life
Since its initial outbreak in late 2019, coronavirus disease 2019 (COVID-19) caused by the novel coronavirus SARS-CoV-2 has ravaged the globe, causing illness characterized by inflammation and impaired oxygen levels.
- Trial name
- PROSPER (NCT04921241)
- Testing
- In Utero Exposure to SARS-CoV-2
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Vaccination Refusal, Communication
Emails Promoting COVID-19 Vaccination Among Healthcare Workers
In this evaluation, two versions of emails will be sent to Geisinger employees who have not been vaccinated against COVID-19. A delayed-contact control group will be emailed after a delay of at least two days.
- Trial name
- NCT04728594
- Testing
- Social Proof, Reframing, Scarcity Message
- Where
- United States
- Volunteers
- 9,566 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
COVID-19 Pneumonia
COVID-19 Hyper Coagulability Care by LLLT
COVID-19 clotting Safety
- Trial name
- LLLT (NCT05271461)
- Testing
- Low level laser Therapy, Circulatory exercises
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
COVID-19, COVID-19 Immunisation
A Study to Evealuate Safety and Immunogenicity of TI-0010 SARS-CoV-2 Vaccine in Healthy Adults
This study is a randomized, double-blind, placebo controlled clinical exploratory study to evaluate the safety, tolerability and immunogenicity of TI-0010 vaccine in healthy adults aged 18-59.
- Trial name
- NCT06205524
- Testing
- TI-0010
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Drug Clinical Trial Institute of the Second Affiliated Hospital of Bengbu Medical College
COVID-19 Testing, Children, Preschool
Back to ECE Safely With SAGE: Reducing COVID-19 Transmission in Hispanic and Low-income Preschoolers
This study aims to get children safely back to school by (1) Child and Family Testing, (2) ECE Personnel Testing, and (3) Outdoor Learning via Garden Education.
- Conditions
- COVID-19 Testing, Children, Preschool, Parents, Child Development
- Trial name
- BESAGE (NCT05178290)
- Testing
- CHILD back-to-ECE COVID-19 saliva testing, ECE personnel back-to-ECE COVID-19 saliva screening, SAGE garden programming
- Where
- United States
- Volunteers
- 1,356 people, healthy volunteers welcome
- Sponsor
- Arizona State University
COVID-19
Study of GRT-R910 COVID-19 Boost Vaccine in Healthy Volunteers
The primary objective was to assess the safety and tolerability of 2 different doses (10 or 30 µg) of GRT-R910 when administered as a boost in healthy adults previously vaccinated with the AstraZeneca, Janssen/Johnson and…
- Trial name
- NCT05148962
- Testing
- GRT-R910
- Where
- 3 sites in United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Gritstone bio, Inc.
COVID-19, Long COVID
CORona (COVID-19) Follow Up Study: Epidemiology, Pathophysiology, Prediction, and Communication
The CORFU study, funded by ZonMW, is a prospective, multiple, cohort study with a maximum follow-up of 24 months after COVID-19.
- Conditions
- COVID-19, Long COVID, Post COVID-19 Condition
- Trial name
- CORFU (NCT05240742)
- Testing
- no intervention, the CORFU study conducts analyses based on data which has been prospectively collected (and aggregated when possible) in 7 existing cohorts
- Where
- Netherlands
- Volunteers
- 4,291 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
SARS-CoV-2, COVID-19
A Study on the Safety and Immune Response of Investigational COVID-19 mRNA Vaccines in Healthy Adults
The purpose of Part A of this study is to assess the immune response and safety of a booster dose of investigational COVID-19 mRNA vaccines in healthy adults.
- Trial name
- NCT05960097
- Testing
- CV0701 mRNA COVID-19 Vaccine (Low dose), CV0701 mRNA COVID-19 Vaccine (Medium dose), CV0701 mRNA COVID-19 Vaccine (High dose)
- Where
- 17 sites in United States, Australia
- Volunteers
- 692 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
COVID-19
Safety and Tolerability of a Newcastle Disease Virus-Based Mucosal COVID-19 Vaccine in Previously Vaccinated Adults
A Double-blind, Randomized, Controlled, Phase 2a Study to Evaluate the Safety and Tolerability of a Newcastle Disease Virus-based Mucosal Vaccine (NDV-HXP-S-KP.2) Relative to an Approved Systemic mRNA Vaccine in Previously…
- Trial name
- NCT07215520
- Testing
- NDV-HXP-S-KP.2, COVID-19 mRNA Vaccine
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- CastleVax Inc.
Inflammatory Disease, Rheumatoid Arthritis
Vaccination Perception in Inflammatory Conditions - Flu, Pneumonia and COVID-19
People with inflammatory diseases are often treated with medications that act to suppress the immune-system, increasing the risk of catching infections.
- Conditions
- Inflammatory Disease, Rheumatoid Arthritis, Psoriatic Arthritis, Systemic Lupus Erythematosus
- Trial name
- OPINION (NCT05115370)
- Testing
- Semi-structured qualitative interview
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Covid19
Optimal Length for Nasal Mid-turbinate and Nasopharyngeal Swabs
This study aim to explore the optimal swap insertion length for mid-turbinate and nasopharyngeal samples. Our clinical trial took place at a Covid-19 test center in Copenhagen.
- Trial name
- NCT04840082
- Testing
- Nasopharyngeal swab for COVID-19 testing
- Where
- Denmark
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
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