Clinical trials: SCI - Spinal Cord Injury
Spinal Cord Injury
DRIV - Health Online for People With Spinal Cord Injury
The goal of this clinical trial is to learn if a 10-week web-based health promotion program ("DRIV") can improve healthy lifestyle habits and overall well-being in adults living with long-term spinal cord injury (SCI).
- Trial name
- DRIV (NCT07473258)
- Testing
- DRIV Program
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Injuries, Spinal Cord
Sit-to-stand in Spinal Cord Injury Patient
1. Were there differences in functional ability between ambulatory individuals with SCI who passed and failed the independent sit-to-stand (iSTS) task? 2.
- Trial name
- NCT02916784
- Volunteers
- 69 people
- Sponsor
- Khon Kaen University
Pressure Ulcers
Implanted Gluteal Stimulation System for Pressure Sore Prevention
This project will evaluate the feasibility of using a fully implanted gluteal stimulation system for the prevention of Pressure ulcers.
- Trial name
- NCT00623948
- Testing
- A fully implanted gluteal stimulation (GSTIM) system
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Spinal Cord Injury
Combined Tactile and Proprioception Training After Spinal Cord Injury
A novel rehabilitation bike has been developed for patients with incomplete spinal cord injuries that incorporates mechanical stimulators on the bike pedals to stimulate the sensory receptors in the soles of the feet; the effect…
- Trial name
- NCT02554058
- Testing
- Cycling and Mechanical stimulation
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Manitoba
Incomplete Spinal Cord Injury, Spinal Cord Injury
Effectiveness of Virtual Bodily Illusion Intervention in Upper Limb Motor Function in People With Incomplete Spinal Cord Injury.
Previous studies have shown that the neuroplasticity of the residual corticospinal fibers, the motor cortex and the spinal neurons plays an important role in the spontaneous functional recovery of people with neurological or…
- Trial name
- NCT05142943
- Testing
- Visual illusion, Physical exercise
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- University of Valencia
Spinal Cord Injury
Treatment for Acute Spinal Cord Injury
This clinical trial aims to treat a damaged spinal cord by injecting your own bone marrow stromal cells (autologous bone marrow stromal cells) into cerebrospinal fluid through the lumbar puncture, and assess the safety and…
- Trial name
- NCT00695149
- Testing
- Transplantation of bone marrow stromal cell
- Where
- Japan
- Volunteers
- 5 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Spinal Cord Injuries, Muscle Spasticity
Cyproheptadine and Chlorpromazine Effects on Spasticity
The main goal of this research is to understand the neuronal mechanisms that mediate the development of spasticity and motor dysfunction after spinal cord injury.
- Trial name
- NCT01509885
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Spinal Cord Injuries
Task-specific Epidural Stimulation Study
The investigators propose to understand the role of lumbosacral spinal cord epidural stimulation (scES) in recovery of autonomic nervous system function, voluntary movement, and standing in individuals with severe spinal cord…
- Trial name
- TSEPI (NCT03364660)
- Testing
- Acute epidural stimulation for cardiovascular stability, Long Term Epidural Stimulation for Cardiovascular Stability, Participants undergo approximately 4 months of epidural stimulation for voluntary movement.
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Louisville
Neuropathic Pain, Spinal Cord Injury
The Effects of Anodal tsDCS on Chronic Neuropathic Pain After SCI
The purpose of this study is to evaluate the analgesic effect of transcutaneous spinal direct current stimulation (tsDCS) applied on spinal cord in patients with spinal cord injury who have chronic neuropathic pain.
- Trial name
- NCT02863315
- Testing
- tsDCS
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Seoul National University Hospital
Spinal Cord Injuries
Spinal Stimulation for Chronic Complete Tetraplegia
The purpose of this study is investigate the acceptability and effectiveness of transcutaneous spinal cord stimulation in people with complete high level spinal cord injury.
- Trial name
- Complete TESCS (NCT05522920)
- Testing
- Therapy with and without spinal cord stimulation
- Volunteers
- 12 people
- Sponsor
- NHS Greater Glasgow and Clyde
Spinal Cord Injuries and Disorders
Mobile Manual Standing Wheelchair for SCI
People with spinal cord injuries (SCI) are particularly prone to complications from excessive sitting, because many are not able to stand without support.
- Trial name
- MMSW-SCI (NCT04668326)
- Testing
- Manual Standing Wheelchair, Mobile Manual Standing Wheelchair
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- VA Office of Research and Development
Spinal Cord Injury, Amyotrophic Lateral Sclerosis
iBCI Optimization for Veterans With Paralysis
VA research has been advancing a high-performance brain-computer interface (BCI) to improve independence for Veterans and others living with tetraplegia or the inability to speak resulting from amyotrophic lateral sclerosis…
- Conditions
- Spinal Cord Injury, Amyotrophic Lateral Sclerosis, Brain Stem Infarctions, Locked-in Syndrome
- Trial name
- NCT05470478
- Testing
- Mobile neural decoding platform (mobile iBCI)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- VA Office of Research and Development
Spinal Cord Injuries
"UroMonitor Trial" in Spinal Cord Injury.
This study aims to determine if a non-functioning UroMonitor device can be safely inserted, monitored, and removed in patients with SCI.
- Trial name
- NCT04800523
- Testing
- UroMonitor System
- Where
- Canada
- Sponsor
- University of British Columbia
Chronic Pain, Spinal Cord Injuries
Improving Functioning in Persons With Chronic Pain Post-SCI Through Virtual Classroom Education
Chronic pain (pain that is that is present for a long period of time) is very common among people with spinal cord injury (SCI).
- Trial name
- NCT02561676
- Testing
- Education Program Type 1, Education Program Type 2
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Kessler Foundation
Spinal Cord Injury
Daily-life Brain Control Of A Hand Exoskeleton After Cervical Spinal Cord Injury
In this study, 6 volunteer participants with chronic spinal cord injury will be invited to use an autonomous hand exoskeleton device controlled by a brain/neural-computer interaction (BNCI) system fusing electroencephalography…
- Trial name
- NCT02336321
- Testing
- BNCI controlled hand exoskeleton
- Where
- Spain
- Volunteers
- 6 people
- Sponsor
- University Hospital Tuebingen
Spinal Cord Injury, Stroke (CVA) or Transient Ischemic Attack
Understanding and Enhancing Human Health and Movement
By doing this study, investigators hope to learn how electrical stimulation can improve human movement, biomechanics, and function and to gather information on the safety and effectiveness of an implanted electrical stimulation…
- Conditions
- Spinal Cord Injury, Stroke (CVA) or Transient Ischemic Attack, Multiple Sclerosis
- Trial name
- NCT07738978
- Testing
- Neural Prosthesis
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Louis Stokes VA Medical Center
Spinal Cord Injury
Acupuncture for Treatment of Acute Spinal Cord Injury: an Exploratory/Developmental Study
Specific Aim: to implement and evaluate a research protocol for demonstrating the efficacy of Acupuncture Therapy to improve neurological recovery after incomplete SCI compared to a control protocol.
- Trial name
- NCT00432289
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Craig Hospital
Spinal Cord Injuries
Exoskeleton and Spinal Cord Injury
The purpose of the current study is to investigate the effects of powered exoskeleton (EKSO) on cardiovascular performance as measured by resting blood pressure and heart rate, peak oxygen consumption during walking, energy…
- Trial name
- EXTra-SCI (NCT03410550)
- Testing
- Exoskeleton Training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- McGuire Research Institute
Spinal Cord Injuries
BioFLO for Respiratory Recovery in SCI
Acute intermittent hypoxia (AIH) involves brief (1 min), repeated episodes (~15) of breathing low oxygen air to stimulate spinal neuroplasticity.
- Trial name
- NCT06011876
- Testing
- Acute Intermittent Hypoxia (AIH), Acute Intermittent Hypercapnic-Hypoxia (AIHH)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Florida
Spinal Cord Injuries, Spinal Cord Injury (SCI), Initial Encounter
Protocol for Rapid Onset of Mobilization in Patients With Traumatic Spinal Cord Injury II (PROMPT-SCI II) Trial
Spinal cord injuries (SCI) are among the most catastrophic survivable events experienced by human beings. Affected individuals remain with lifelong neurological impairment involving motor, sensory, bladder and bowel functions…
- Trial name
- PROMPT-SCI II (NCT07472985)
- Testing
- activity-based therapy
- Where
- Canada
- Volunteers
- 102 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal