Clinical trials: SHARK
Phase 1b, HC-7366
A Phase 1b Study of HC-7366, an Agonist of ISR With Immunotherapy in Kidney Cancer (SHARK)
To find out if the combination of HC-7366 and nivolumab (with or without ipilimumab) can help to control ccRCC. The
- Conditions
- Phase 1b, HC-7366, SHARK, Kidney Cancer
- Trial name
- NCT07401875
- Testing
- Nivolumab, HC-7366, ipilimumab
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- M.D. Anderson Cancer Center
Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Reconstruction
ACL Reconstruction With Shark Screw® or Biocomposite-interference Screws
The goal of this clinical trial is to compare the outcome of 2 different screws for Anterior cruciate ligament reconstruction. The main question is if the human allogeneic cortical bone screw reduces tunnel widening in comparison…
- Conditions
- Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Reconstruction, Anterior Cruciate Ligament Injury
- Trial name
- NCT06357091
- Testing
- ACL reconstruction with Shark Screw ACL®, ACL reconstruction with biocomposite screw (Mecta)
- Where
- Austria
- Volunteers
- 80 people
- Sponsor
- Alexander Rofner-Moretti
Hallux Valgus
Hallux Valgus Correction Using the Metal Screw or the Human Allogeneic Cortical Bone Screw (Shark Screw).
The goal of this clinical trial is to compare the treatment of Hallux Valgus using the conventional method (metal screw) with the new method (human allogeneic cortical bone screw (Shark Screw®) in adult patients with confirmed…
- Trial name
- NCT06262204
- Testing
- Hallux Valgus Treatment with Shark Screw®, Hallux Valgus Treatment with metal screw
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Orthopedic Hospital Vienna Speising
Arthrodesis, Osteotomy
Shark Screw® - Hand- and Foot Surgery Study
This observational study aims to determine the efficacy and safety of the Shark Screw® transplant for osteotomy and arthrodesis in hand and foot surgery.
- Trial name
- NCT04109469
- Testing
- Shark Screw® transplant
- Where
- Austria
- Volunteers
- 32 people
- Sponsor
- Klinik Diakonissen Linz GmbH
ADHD
A Study on the Inter-Hemispheric Alpha Ratio in Kids With ADHD (SHARK)
Investigate the hypothesis that children with ADHD have difficulty with the allocation of visio-spatial attention related to an inability to control posterior alpha brain oscillations.
- Trial name
- SHARK (NCT01932398)
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Pancreatic Cancer, Periampullary Carcinoma
Shark Mouth Modified Pancreaticojejunostomy
Pancreaticoduodenectomy (PD) is one of the most complicated surgical procedure and one of the standard treatments for benign and malignant disease of pancreatic head and periampullary region.
- Trial name
- SMMP (NCT03366038)
- Testing
- Shark Mouth Modified Pancreaticojejunostomy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Keratoconus
Simultaneous pHototherapeutic Keratectomy and corneAl Collagen cRosslinking in Eyes With Keratoconus: a Randomized Trial (SHARK)
The goal of this clinical trial is to compare CXL with combined treatment with CXL and t-PTK. The main questions it aims to answer are whether combined treatment can give better visual acuity and if the treatments are equally…
- Trial name
- NCT06264024
- Testing
- Corneal collagen cross linking (CXL), Transepithelial phototherapeutic keratectomy (t-PTK)
- Where
- Norway
- Volunteers
- 81 people
- Sponsor
- Oslo University Hospital
Breast Cancer, Colorectal Cancer
Shark Cartilage in Treating Patients With Advanced Colorectal or Breast Cancer
RATIONALE: Shark cartilage extract may help shrink or slow the growth of colorectal cancer or breast cancer cells. PURPOSE: Randomized phase III trial to determine the effectiveness of shark cartilage in treating patients who…
- Trial name
- NCT00026117
- Testing
- BenFin
- Where
- 16 sites in United States
- Volunteers
- 88 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Flat Feet, Flexor Tendon Rupture
Medial Displacement Calcaneal Osteotomy and FDL- Transfer - With a Human, Allogeneic Cortical Bone Screw
The goal of this observational study is to compare the use of a screw made of human bone (Shark-Screw®, Surgebright-GmbH) with the metal/Bio-Tenodesis screw (Arthrex) in the treatment of the symptomatic flatfoot using the…
- Conditions
- Flat Feet, Flexor Tendon Rupture, Tibialis Posterior Dysfunction, Deformity, Foot
- Trial name
- NCT05643079
- Testing
- medializing calcaneal osteotomy and/or transfer of the flexor digitorum longus tendon (FDL) with metal/Bio-Tenodesis screws, medializing calcaneal osteotomy and/or transfer of the flexor digitorum longus tendon (FDL) with Shark Screws®
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Orthopedic Hospital Vienna Speising