Clinical trials: SNS
Menopause
Pilot Study - Impact of Traditional Acupuncture on Menopause
This pilot project is a randomized research study to examine the effects of acupuncture on menopausal symptoms. The investigators will recruit up to 45 Cedars employees (excluding Dr Bairey Merz's employees) with menopausal…
- Trial name
- NCT00950482
- Testing
- TA, AA, WC
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Fusion of Spine, Sympathetic Nervous System
Comparison of Surgical Outcomes Between Pre Sympathetic Plexus and Post Sympathetic Plexus Approach
There would be no difference in the risk of sympathetic plexus damage between the pre sympathetic plexus approach and the post sympathetic plexus approach.
- Trial name
- NCT04891432
- Testing
- Lateral lumbar interbody fusion
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Seoul National University Hospital
Rosacea
Role of the Sympathetic Nervous System in Rosacea
Rosacea is a common skin disorder which causes facial redness and inflammation in about 16 million Americans, from an unknown cause.
- Trial name
- NCT03989492
- Testing
- systemic and local stressors
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kristen Metzler-Wilson
Cardiovascular Diseases
Virtual Reality-based Therapy and Barriers in Cardiac Patients
The aim of this study is to investigate the chronic hemodynamic and autonomic repercussions of the insertion of VRBT in CR. To qualitatively analyze the perception of patients and physiotherapists regarding the use of VRBT, as…
- Trial name
- NCT04336306
- Testing
- virtual reality-based therapy (VRBT)
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Menopause
Cortisol Levels on Menopausal Symptoms - Ancillary (Addendum) Study to Protocol 16997
This is an ancillary study to Protocol 16997 to examine the stress hormone level in women with menopausal symptoms. This ancillary project will collect additional data from the 45 subjects enrolled in Protocol 16997 (no subjects…
- Trial name
- NCT00950781
- Testing
- ACTH
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Upper Limb Nerve Block
The Study of Regional Hemodynamic Changes After Specific Brachial Plexus Block by Ultrasound Guidance
Phase 1 Sympathetic block leads to vasodilatation and increases in blood flow. However, regional hemodynamic changes of radial and ulnar artery after specific nerve block of brachial plexus remains unclear.
- Trial name
- NCT02139982
- Testing
- specific nerve block, ropivacaine
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Wenzhou Medical University
Chronic Kidney Diseases, Heart Failure
REducing Sympathetic Activity Through Ultrasound-based Renal deneRvation in Excessive Cardiovascular Risk populaTions.
The is a non-randomized pilot trial, open-label evaluation of the physiologic response of native kidney denervation using the Paradise denervation system in CKD, End Stage Renal Disease (ESRD), and Heart failure (HF)
- Conditions
- Chronic Kidney Diseases, Heart Failure, End Stage Renal Disease
- Trial name
- RESURRECT (NCT05703620)
- Testing
- Renal Denervation
- Where
- Australia
- Volunteers
- 75 people
- Sponsor
- Royal Perth Hospital
POTS - Postural Orthostatic Tachycardia Syndrome
RESET-POTS: Multimodal Phenotyping and Stellate Ganglion Block in Postural Orthostatic Tachycardia Syndrome
RESET-POTS is a pilot study for adults with postural orthostatic tachycardia syndrome (POTS), a condition that can cause a rapid increase in heart rate, dizziness, weakness, fatigue and other symptoms when standing.
- Trial name
- RESET-POTS (NCT07837804)
- Testing
- Bilateral Sequential Stellate Ganglion Block
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Healthy Volunteers, Normal Physiology
Reference Values for Plasma Catechols
Objectives: Plasma levels of catechols have distinct meanings in terms of indicating functions of endogenous catecholamine systems.
- Trial name
- NCT00267904
- Testing
- Coffee, Banana, Olives
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Uncontrolled Hypertension
Netrod-Pilot Study of Renal Denervation With NetrodTM Sixelectrode Radiofrequency RDN System
This single-arm, non-randomized, open-label investigation aims to collect safety and efficacy data of the CE-Marked Netrod™ RDN System in treating European patients with primary hypertension in the absence of anti-hypertensive…
- Trial name
- NCT07061054
- Testing
- Netrod™ six-electrode radiofrequency renal denervation system
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Shanghai Golden Leaf MedTec Co. Ltd
Type 2 Diabetes
SGLT2i, Hepatic Glucose Production, and SNS
In this study, PI will test the hypothesis that distinct mechanisms account for the SGLT2i-induced stimulation of ketogenesis and lipolysis versus endogenous (hepatic) glucose production in patients with type 2 diabetes (T2D)…
- Trial name
- NCT07053293
- Testing
- Empagliflozin 25 MG
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Healthy, Autonomic Nervous System Diseases
Prevalence of Chapman Reflex Points in Medical Students and Their Association With Visceral Symptoms
Chapman Reflex Points (CRPs) are small palpable nodules found within connective tissue that have traditionally been associated with dysfunction of internal organs and the autonomic nervous system.
- Conditions
- Healthy, Autonomic Nervous System Diseases, Lymphatic Diseases, Somatic Dysfunction
- Trial name
- NCT07691112
- Testing
- Chapman Reflex Point Examination
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- The Touro College and University System
Arterial Hypertension, Resistant Arterial Hypertension
Systemic Microvascular Function in Patients With Resistant Hypertension After Renal Sympathetic Denervation
It has been proposed that the modulation of the activity of the sympathetic nervous system, through renal sympathetic denervation, besides reducing blood pressure, would promote an improvement in vascular reactivity and…
- Trial name
- NCT03243045
- Testing
- Renal sympathetic denervation
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Essential Hypertension
The Effect of Eprosartan on Hormones and Kidney Function in Patients With Essential Hypertension
We, the investigators at Holstebro Hospital, want to test the hypothesis that eprosartan reduces the activity of the sympathetic nervous system in patients with essential hypertension - during baseline conditions and after…
- Trial name
- NCT00438945
- Testing
- Eprosartan
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- Regional Hospital Holstebro
Syncope
Propranolol to Treat Fainting in Children With Sympathoadrenal Imbalance
This study will examine the effectiveness of the drug propranolol in preventing fainting in patients with sympathoadrenal imbalance (SAI).
- Trial name
- NCT00093860
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Obstructive Sleep Apnea (OSA), CPAP
Sleep Apnea Biomarkers and Adherence to Continuous Positive Airway Pressure
Obstructive sleep apnea (OSA) is commonly assessed using the apnea-hypopnea index, although this measure does not fully reflect cardiovascular risk or the physiological impact of the disease.
- Conditions
- Obstructive Sleep Apnea (OSA), CPAP, Biomarkers for Prediction of OA Treatment Efficacy
- Trial name
- BIOSA (NCT07792746)
- Testing
- Continuous Positive Airway Pressure
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Clinique du Millenaire
Complex Regional Pain Syndrome Type I, Complex Regional Pain Syndrome Type II
Neurotropin to Treat Chronic Neuropathic Pain
This study will examine the effectiveness of the drug neurotropin in treating chronic pain after injury to a limb or a large nerve.
- Trial name
- NCT00006289
- Testing
- Neurotropin
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- National Institute of Nursing Research (NINR)
Metabolic Syndrome X
Sympathetic Activity in Individuals With the Metabolic Syndrome: Benefits of Lifestyle Interventions
An abdominal distribution of fat is associated with the greatest heart disease risk, because commonly, several risk factors of metabolic origin (high blood pressure, unfavourable cholesterol profile, elevated blood sugar…
- Trial name
- NCT00163943
- Testing
- Dietary weight loss +/- aerobic exercise
- Where
- Australia
- Volunteers
- 66 people
- Sponsor
- Bayside Health
Refractory Overactive Bladder
Clinical Trial of Sacral Neuromodulation for Treatment of Refractory Overactive Bladder (OAB)
Evaluate the long-term clinical effectiveness and safety of the PINS Sacral Neuromodulation to patients with refractory Overactive Bladder.
- Trial name
- NCT02619721
- Testing
- PINS SNS
- Where
- China
- Volunteers
- 7 people
- Sponsor
- Beijing Pins Medical Co., Ltd
Osteoarthritis of Multiple Joints of Ankle or Foot, Healthy
Effects of Opioids and NSAIDs on Sympathetic Nervous System and Vascular Function
Evaluation of the effect of different analgesic treatments (Tramadol, Paracetamol, Diclofenac) on sympathetic nerve activity, blood pressure, heart rate, heart rate, and vascular function in osteoarthritis patients and healthy…
- Trial name
- OPIOVASC (NCT03781544)
- Testing
- Tramadol, Paracetamol, Diclofenac
- Where
- Switzerland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Zurich