Clinical trials: SOX2
Colorectal Cancer
Identification the Expression of Sox2 in Colorectal Cancer Tissues
Sox2 has been studied in several types of human solid tumors. The investigators found that Sox2 had higher expression level in colorectal cancer and metastatic tissues than normal tissues.
- Trial name
- NCT01589900
- Volunteers
- 136 people
- Sponsor
- Sun Yat-sen University
Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
STEMVAC in Patients With Early Stage Triple Negative Breast Cancer
This phase II trial studies the effect of DNA plasmid based vaccine (STEMVAC) in treating patients with patients with stage IB-III triple negative breast cancer.
- Conditions
- Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIA Breast Cancer AJCC v8, Anatomic Stage IIB Breast Cancer AJCC v8
- Trial name
- NCT05455658
- Testing
- CD105/Yb-1/SOX2/CDH3/MDM2-polyepitope Plasmid DNA Vaccine, Sargramostim
- Where
- 3 sites in United States
- Volunteers
- 33 people
- Sponsor
- University of Washington
Odontogenic Cysts, Odontogenic Tumors
Evaluation of the Expression and Prognostic Role of Tumor Stem Cell Marker SOX2 in Odontogenic Cysts and Tumors
The pathogenesis of odontogenic lesions remains unclear; however, a probable explanation may involve the existence of tumor stem cells (TSCs), which are thought to generate both benign and malignant tumors.
- Trial name
- NCT06833840
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Mansoura University
TOR1A, PANK2
Deep Brain Stimulation (DBS) MatchMaker
DBS Matchmaker (https://www.dbsmatchmaker.com) is a platform designed to connect clinicians worldwide who are treating rare movement disorders with deep brain stimulation (DBS).
- Conditions
- TOR1A, PANK2, HPRT1, EIF2AK2
- Trial name
- DBSMatchMaker (NCT06912841)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Boston Children's Hospital
Urinary Bladder Neoplasm
SOX2 & PDL1 Expression on Urinary Bladder Carcinoma
Bladder carcinoma (BC) is the 13th leading cause of cancer mortality worldwide . In Egypt, BC is the third common malignant tumor.
- Trial name
- NCT05429710
- Volunteers
- 60 people
- Sponsor
- Sohag University
Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Triple-Negative Breast Carcinoma
A Cancer Vaccine (STEMVAC) in Combination With Chemotherapy for the Treatment of PD-L1 Negative Metastatic Triple-Negative Breast Cancer
This phase II trial studies how well a cancer vaccine called STEMVAC works in combination with chemotherapy in treating patients with PD-L1 negative, triple-negative breast cancer that has spread from where it first started…
- Trial name
- NCT07078604
- Testing
- CD105/Yb-1/SOX2/CDH3/MDM2-polyepitope Plasmid DNA Vaccine, Chemotherapy, Computed Tomography
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Washington