Clinical trials: ST Segment Elevation Myocardial Infarction (STEMI)
Vascular Diseases, Cardiovascular Diseases
The Long-term and Short-term Efficacy and Safety of Transplantation Autologous Bone Marrow Cells (BMCs) in Patients With the First STEMI (ST Segment Elevation Myocardial Infarction)
The purpose of this study is to test the hypothesis that the intracoronary transplantation of autologous mononuclear and CD 133 + bone marrow cells will improve left ventricular contractile function and will reduce the combined…
- Conditions
- Vascular Diseases, Cardiovascular Diseases, Acute Myocardial Infarction
- Trial name
- ESTABOMA (NCT01748383)
- Testing
- Transplantation of BMMCs, Transplantation of CD 133+ cells, stenting of IRA
- Where
- Russia
- Volunteers
- 85 people
- Sponsor
- Russian Academy of Medical Sciences
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-III Belgium Satellite Registry
This registry is a clinical post-market evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES).
- Trial name
- NCT01831336
- Where
- 8 sites in Belgium
- Volunteers
- 332 people
- Sponsor
- Biotronik Belgium NV
Acute Coronary Syndrome
Effect of Otamixaban Versus Unfractionated Heparin + Eptifibatide in Patients With Unstable Angina/Non ST Elevation Myocardial Infarction Undergoing Early Invasive Strategy
Primary Objective: To demonstrate the superior efficacy (composite of all-cause death + Myocardial Infarction (MI)) of Otamixaban to Unfractionated Heparin (UFH) + Eptifibatide Secondary Objectives: To demonstrate the superior…
- Trial name
- TAO (NCT01076764)
- Testing
- Otamixaban, UFH, Eptifibatide
- Where
- 607 sites in United States, Argentina and 53 more
- Volunteers
- 13,220 people
- Sponsor
- Sanofi
Myocardial Infarction
Safety of Early Discharge Following Low Risk Myocardial Infarction
Objectives: The primary objective of this study is to evaluate the safety of an early discharge strategy in patients with low risk ST-elevation myocardial infarction (STEMI), treated with primary percutaneous coronary…
- Trial name
- EDAMI (NCT01868256)
- Testing
- early discharge (<72 h), Conventional discharge
- Where
- Spain
- Volunteers
- 1,558 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Atrial Fibrillation
Artificial Intelligence Models to Predict Clinically Relevant Cardiovascular Outcomes
Atrial fibrillation (AF) is a frequent and clinically relevant problem among the events that may occur during the hospitalization period in patients with cardiovascular disease.
- Trial name
- PERCARD (NCT06847100)
- Testing
- Blood withdrawal
- Where
- 4 sites in Finland, Germany and 1 more
- Volunteers
- 273 people
- Sponsor
- Centro Cardiologico Monzino
Acute Myocardial Infarction With ST Elevation, Anterior Wall Myocardial Infarction
Deferred Stenting in Patients With Anterior Wall STEMI
Trial Name) Impact of Immediate SteNt ImplaNtatiOn Versus Deferred Stent ImplAntaTION on Clinical Outcomes in Patients with AnteRior Wall ST-segment Elevation Myocardial Infarction (INNOVATION-CORE) Objectives) To evaluate the…
- Trial name
- INNOVATIONCORE (NCT03744000)
- Testing
- Immediate stenting, Deferred stenting
- Where
- South Korea
- Volunteers
- 185 people
- Sponsor
- Korea University Anam Hospital
Myocardial Infarction, Heart Failure
Henagliflozin Reducing Infarct Size After Priamry PCI in Patients With ST Segment Elevation Myocardial Infarction
This Randomized controlled intervention study recruited patients diagnosed with ST-segment elevation myocardial infarction (STEMI). A total of 240 patients were enrolled in either Henagliflozin group or control group.
- Trial name
- Health (NCT06187727)
- Testing
- Henagliflozin
- Where
- China
- Volunteers
- 248 people
- Sponsor
- Qian geng
Hyperglycemia
Trhombus Aspiration in Hyperglycemic ST-elevation myocardiAl InfarcTIon
Background. Patients with ST-Elevation Myocardial Infarction (STEMI) and hyperglycemia on admission have high rates of mortality (1). The management of hyperglycemic patients during STEMI is unclear.
- Trial name
- TAHITI (NCT02817542)
- Testing
- percutaneous coronary intervention
- Where
- Italy
- Volunteers
- 990 people
- Sponsor
- University of Campania Luigi Vanvitelli
Coronary Artery Disease, Percutaneous Coronary Intervention
Thrombus Aspiration in Heavy Thrombus Burden Acute ST-elevation Myocardial Infarction
Recent guidelines for the management of ST-elevation myocardial infarction (STEMI) recommend against the routine use of thrombus aspiration (TA) during primary percutaneous coronary intervention (PPCI) (Class III indication).
- Conditions
- Coronary Artery Disease, Percutaneous Coronary Intervention, ST Elevation Myocardial Infarction
- Trial name
- TSUNAMI (NCT04912570)
- Testing
- Manual Thrombus Aspiration, Standard PCI
- Where
- 4 sites in Egypt
- Volunteers
- 124 people
- Sponsor
- The Young Investigator Group of Cardiovascular Research
Anterior Myocardial Infarction
A Research Study to Evaluate the Safety and Preliminary Efficacy of SGC001 in Patients With Myocardial Infarction
The research study is being done to see if SGC001 can be used to treat people scheduled to undergo percutaneous coronary intervention for Anterior ST-segment Elevation Myocardial Infarction.
- Trial name
- NCT07091929
- Testing
- SGC001
- Where
- 4 sites in China
- Volunteers
- 38 people
- Sponsor
- Beijing Sungen Biomedical Technology Co., Ltd
NSTEMI - Non-ST Segment Elevation MI, STEMI (ST Elevation MI)
Aspirin-free Strategy With Ticagrelor in Patients With a Myocardial Infarction Treated Medically Alone
In patients with a myocardial infarction (MI) treated medically alone, the objective of the PANTHEON trial is to evaluate if ticagrelor monotherapy reduces bleeding events, without an increase in patient-oriented ischemic events…
- Conditions
- NSTEMI - Non-ST Segment Elevation MI, STEMI (ST Elevation MI), Myocardial Infarction
- Trial name
- PANTHEON (NCT07257198)
- Testing
- Ticagrelor + aspirin
- Where
- Canada
- Volunteers
- 2,570 people
- Sponsor
- Montreal Heart Institute
Non ST Segment Elevation Myocardial Infarction, Unstable Angina
Patients With High-risk Acute Coronary Syndrome Without ST-segment Elevation
This non-inferiority study aims at comparing Versa® to the reference enoxaparin (Clexane®, Sanofi-Aventis) in patients with high-risk unstable angina and NSTEMI.
- Trial name
- VECOR (NCT01356992)
- Testing
- Enoxaparin
- Where
- 5 sites in Brazil
- Volunteers
- 62 people
- Sponsor
- Eurofarma Laboratorios S.A.
Myocardial Infarction
Chronic Remote Ischemic Conditioning to Modify Post-MI Remodeling
During a heart attack, an artery carrying blood and oxygen to the heart becomes blocked, which causes damage to the heart muscle.
- Trial name
- CRIC-RCT (NCT01817114)
- Testing
- Auto Remote Ischemic Conditioning (AutoRIC) device
- Where
- 3 sites in Canada
- Volunteers
- 20 people
- Sponsor
- The Hospital for Sick Children
Acute Coronary Syndrome, STEMI
Chewing Ticagrelor Versus Prasugrel in ST-elevation Myocardial Infarction - A Platelet Reactivity Study
To examine the efficacy of chewing Ticagrelor versus Prasugrel in ST-elevation Myocardial Infarction (STEMI) patients on platelet reactivity.
- Trial name
- NCT03016611
- Testing
- Chewing Ticagrelor LD, Chewing Prasugrel LD
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Acute Coronary Syndrome, STEMI
EKG Criteria and Identification of Acute Coronary Occlusion
The objective of this research study is to test the accuracy of preexisting criteria versus expert interpretation for the diagnosis of acute coronary occlusion (major heart attack due to a completely blocked blood vessel).
- Conditions
- Acute Coronary Syndrome, STEMI, STEMI - ST Elevation Myocardial Infarction, Acute Coronary Artery Thrombosis (Diagnosis)
- Trial name
- NCT03863327
- Testing
- No intervention
- Where
- 2 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- Stony Brook University
STEMI, Cardiogenic Shock
Circulating microRNAs in Patients With STEMI Complicated With Cardiogenic Shock
The aim of the study is knowing the prognostic value of circulating miRNAs in patients admitted to our hospital with STEMI complicated with cardiogenic shock.
- Conditions
- STEMI, Cardiogenic Shock, Acute Coronary Syndrome, microRNA
- Trial name
- NCT02691286
- Where
- Spain
- Volunteers
- 142 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
ST Elevation Myocardial Infarction, C-Reactive Protein
CRP Apheresis in STEMI
Background: In patients with acute ST-elevation myocardial infarction (STEMI), the amount of infarcted myocardium (infarct size) is known to be a major predictor for adverse remodeling and recurrent adverse cardiovascular events.
- Conditions
- ST Elevation Myocardial Infarction, C-Reactive Protein, Apheresis, Myocardial Injury
- Trial name
- NCT04939805
- Testing
- Selective CRP apheresis using the PentraSorb®-CRP system
- Where
- 5 sites in Austria, Germany
- Volunteers
- 202 people
- Sponsor
- Medical University Innsbruck
ST-Segment Elevation Myocardial Infraction
IK-1001 (Sodium Sulfide (Na2S) for Injection) in Subjects With Acute ST-Segment Elevation Myocardial Infarction
Myocardial Infarctions (MI) are commonly known as heart attacks. An ST-Segment Elevation Myocardial Infarction (STEMI) is a more severe type of heart attack.
- Trial name
- NCT01007461
- Testing
- Sodium Sulfide (Na2S) for Injection
- Sponsor
- Mallinckrodt
ST-segment Elevation Myocardial Infarction (STEMI), Diabetes Mellitus
Effect of Dapagliflozin in Myocardial Fibrosis and Ventricular Function in Patients With a ST-segment Elevation Myocardial Infarction
The DAPA-STEMI trial investigates whether dapagliflozin, a sodium-glucose cotransporter 2 inhibitor (SGLT2i), reduces heart muscle scarring (fibrosis) and improves heart function after a ST-segment elevation myocardial infarction…
- Conditions
- ST-segment Elevation Myocardial Infarction (STEMI), Diabetes Mellitus, Heart Failure, Myocardial Fibrosis
- Trial name
- DAPA-STEMI (NCT06619600)
- Testing
- Dapagliflozin
- Where
- 2 sites in Spain
- Volunteers
- 54 people
- Sponsor
- Hospital Clinic of Barcelona
Myocardial Infarction
Intracoronary Darbepoetin-alpha to Reduce The Infarct Size and Post-Infarct Remodeling
Prospective, randomized and open label trial Hypothesis Infusion of intracoronary darbepoetin-alpha at the time of reperfusion may reduce infarct size and post-infarct pathologic left ventricular remodeling in patients with…
- Trial name
- NCT01538771
- Testing
- Darbepoetin alfa, Control Saline
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Bundang Hospital
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