Clinical trials: ST Segment Elevation Myocardial Infarction (STEMI)
Essential Hypertension
Protective Effect of Beraprost Sodium Tablets on Reperfusion Therapy for Acute STEMI
Protective effect of Beraprost Sodium Tablets on coronary microcirculation function and ventricular remodeling after reperfusion therapy for acute ST segment elevation myocardial infarction
- Trial name
- NCT05103813
- Testing
- Beraprost Sodium Tablets
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shenzhen People's Hospital
Acute Myocardial Infarction
OPTical Coherence Tomography IMAging in Patients With Acute myocardiaL Infarction (OPTIMAL)
The purpose of the study is to investigate the clinical outcomes, safety and cost-effectiveness of intravascular OCT imaging in patients with acute myocardial infarction undergoing percutaneous coronary intervention (PCI).
- Trial name
- OPTIMAL (NCT03084991)
- Where
- 20 sites in China
- Volunteers
- 4,500 people
- Sponsor
- Harbin Medical University
Primary PCI
Different β -Blockers in STEMI and Primary PCI
Carvedilol, target dose: 50 mg daily; Bisoprolol, target dose: 10 mg daily; Metoprolol tartrate, target dose: 150 mg daily; Metroprolol succinate, target dose: 200 mg daily
- Trial name
- NCT04221919
- Testing
- β -Blockers
- Volunteers
- 1,200 people
- Sponsor
- Qilu Hospital of Shandong University
Acute Myocardial Infarction, Non-ST Elevation Myocardial Infarction
Evaluation of Decreased Usage of Betablockers After Myocardial Infarction in the SWEDEHEART Registry (REDUCE-SWEDEHEART)
Long-term beta-blocker therapy has not been investigated in contemporary randomized clinical trials in patients with myocardial infarction and normal heart function.
- Conditions
- Acute Myocardial Infarction, Non-ST Elevation Myocardial Infarction, ST Elevation Myocardial Infarction
- Trial name
- NCT03278509
- Testing
- Metoprolol Succinate, Bisoprolol
- Where
- Sweden
- Volunteers
- 5,000 people
- Sponsor
- Karolinska Institutet
ST Elevation Myocardial Infarction
Ticagrelor Versus Clopidogrel in Left Ventricular Remodeling After ST-segment Elevation Myocardial Infarction
The purpose of the study is to evaluate the novel role of ticagrelor to improve long-term LV remodeling following ST-segment elevation myocardial infarction.
- Trial name
- HEALING-AMI (NCT02224534)
- Testing
- Ticagrelor, Clopidogrel
- Where
- 12 sites in China, Singapore and 1 more
- Volunteers
- 326 people
- Sponsor
- Gyeongsang National University Hospital
Myocardial Reperfusion Injury, Treatment Outcome
Clinical Efficacy of Extracorporeal Cardiac Shock Wave Therapy in Patients With Ischemia-reperfusion Injury
This trial was a prospective, open-label, single-center, randomized trial, To observe the clinical efficacy of extracorporeal cardiac shock wave in the treatment of patients with myocardial ischemia-reperfusion injury and the…
- Conditions
- Myocardial Reperfusion Injury, Treatment Outcome, Prognosis, ST Elevation Myocardial Infarction
- Trial name
- CEECSWIRI (NCT05624203)
- Testing
- Extracorporeal cardiac shock wave therapy(ECSW)
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital of Kunming Medical University
Ischemic Heart Disease, Non STEMI
Coronary Computed Tomography Versus Invasive Angiography for Non-ST Elevation Acute Coronary Syndrome
Coronary computed tomography angiography (CCTA) is a widely accepted initial diagnostic test for individuals suspected of having chronic coronary syndromes.
- Conditions
- Ischemic Heart Disease, Non STEMI, Angina Pectoris, Unstable, Coronary Disease
- Trial name
- TRACTION (NCT06101862)
- Testing
- CCTA, Conventional ICA, Team-based interventional triage
- Where
- 6 sites in Denmark
- Volunteers
- 2,300 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
STEMI, Acute Myocardial Infarction
Antiplatelets and Intramyocardial Hemorrhage in STEMI: Incidence and Outcomes
The MIRON-PLATELET study is a retrospective, observational multi-center analysis assessing the impact of different antiplatelet therapies on hemorrhagic myocardial infarction (HMI) incidence and outcomes in STEMI patients.
- Trial name
- MIRON-PLATELET (NCT06851325)
- Where
- United States
- Volunteers
- 6,180 people
- Sponsor
- Rohan Dharmakumar
STEMI - ST Elevation Myocardial Infarction
Comparative Evaluation of Sustained meChanical AsPiration Thrombectomy and no Thrombus Modification for Pre-stent Thrombus bUrden Reduction in Patients With Acute Myocardial Infarction Study: the CAPTURE AMI Study
The CAPTURE AMI trial is an investigator-initiated, single-centre, two-arm, randomised controlled trial. Patients aged ≥ 18 years who present with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous…
- Trial name
- CAPTURE AMI (NCT07687576)
- Testing
- Sustained thrombectomy, Percutaneous Coronary Intervention
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Oxford University Hospitals NHS Trust
Acute ST-segment Elevation Myocardial Infarction
Effect of Low-dose Intracoronary Reteplase on Myocardial Infarct Size During Primary Percutaneous Coronary Intervention
OBJECTIVE: To determine whether a therapeutic strategy involving low-dose intracoronary fibrinolytic therapy with reteplase infused after coronary reperfusion will reduce the myocardial infarction size.
- Trial name
- RECOVERII (NCT04571580)
- Testing
- Normal Saline, Reteplase Injection 9mg, Reteplase Injection 18mg
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Ge Junbo
Microvascular Coronary Artery Disease, STEMI
Clinical Trial for Evaluating the Effectiveness and Safety of Online caIMR in STEMI Patients
Despite the success of restoration of epicardial blood flow by the primary percutaneous coronary intervention (PPCI), approximately a half of patients with ST-segment elevation myocardial infarction (STEMI) have failed myocardial…
- Trial name
- FlashIV (NCT06118450)
- Testing
- Non-intervention
- Where
- 8 sites in China
- Volunteers
- 335 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Acute Coronary Syndrome, Non-ST Elevation (NSTEMI) Myocardial Infarction
An Efficacy and Outcome Study of Supplemental Oxygen Treatment in Patients With Suspected Myocardial Infarction
The use of supplemental oxygen in the setting of suspected acute myocardial infarction (AMI) is manifested in international treatment guidelines and established in prehospital and hospital clinical routine throughout the world.
- Conditions
- Acute Coronary Syndrome, Non-ST Elevation (NSTEMI) Myocardial Infarction, Acute ST Segment Elevation Myocardial Infarction, Angina, Unstable
- Trial name
- DETO2X-AMI (NCT01787110)
- Testing
- Oxygen
- Where
- 34 sites in Sweden
- Volunteers
- 6,629 people
- Sponsor
- Karolinska Institutet
Myocardial Infarction
Relationship Between Primary Percutaneous Coronary Intervention, Door-to-balloon Times, and Mortality for Heart Attack Patients Across England
The degree to which elevated mortality associated with weekend or night-time hospital admissions reflects poorer quality of care ('off-hours effect') is a contentious issue.
- Trial name
- NCT02374190
- Testing
- Standard Hospital Care
- Where
- United Kingdom
- Volunteers
- 42,677 people
- Sponsor
- London School of Economics and Political Science
Non-ST-Elevation Myocardial Infarction
Thrombus Aspiration During Percutaneous Coronary Intervention in Acute Non-ST-elevation Myocardial Infarction Study
In this trial, the investigators will evaluate the effect of thrombus aspiration followed by stent implantation in improving myocardial blush grade in patients with acute non-ST-elevation myocardial infarction compared to…
- Trial name
- TAPAS II (NCT01013038)
- Testing
- Thrombus aspiration followed by stent implantation, conventional PCI
- Where
- Netherlands
- Volunteers
- 540 people
- Sponsor
- University Medical Center Groningen
Left Ventricular Thrombus, ST Segment Elevation Myocardial Infarction
Rivaroxaban vErsus Warfarin for Antithrombotic TheRapy in Patients With LeFt Ventricular Thrombus After Acute STEMI
The purpose of the study is to assess the safety and efficacy of rivaroxaban-based versus warfarin-based antithrombotic regimens on outcomes of patients with left ventricle thrombosis following acute ST elevation myocardial…
- Trial name
- REWARF-STEMI (NCT05705089)
- Testing
- Rivaroxaban 15 MG, Warfarin
- Where
- 2 sites in Iran
- Volunteers
- 50 people
- Sponsor
- Rajaie Cardiovascular Medical and Research Center
ST-elevation Myocardial Infarction
Primary Reperfusion Secondary Stenting Trial
The purpose of this research project is to improve how we treat heart attacks. The study will assess whether it might not be better to wait a few hours before implanting the coronary stent into the coronary artery rather than…
- Trial name
- PRIMACY (NCT01542385)
- Testing
- Stent
- Where
- 16 sites in Canada, France
- Volunteers
- 307 people
- Sponsor
- Montreal Heart Institute
ST-elevation Myocardial Infarction
Effect of Conditioning on Myocardial Damage in STEMI
The LIPSIA-Conditioning trial is an investigater initiated, randomized, single-center study that will assess the effect of different intrahospital conditioning protocols on myocardial damage assessed by MRI in patients with acute…
- Trial name
- LIPSIA-COND (NCT02158468)
- Testing
- Combined intrahospital pre- and postconditioning, Postconditioning
- Where
- Germany
- Volunteers
- 600 people
- Sponsor
- University of Leipzig
Unstable Angina, Myocardial Infarction
Early Versus Delayed Timing of Intervention in Patients With Acute Coronary Syndromes
The timing of intervention study is a prospective, randomized, international, multicentre comparison of the relative efficacy, safety, and cost effectiveness of a management strategy of coronary angiography and intervention…
- Trial name
- TIMACS (NCT00552513)
- Testing
- Early Coronary Intervention, Delayed Coronary Intervention
- Where
- Canada
- Volunteers
- 3,031 people
- Sponsor
- Population Health Research Institute
ST Elevation Myocardial Infarction
STEMI Treatment Optimization by Ischemic Postconditioning and IVUS Guidance
The purpose of is study is to investigate whether ischemic postconditioning (iPOST) and intravascular ultrasound-guided (IVUS) percutaneous coronary intervention (PCI) improve the clinical outcome of patients with ST-segment…
- Trial name
- DANAMI4 (NCT04775914)
- Testing
- PCI + Ischemic conditioning, Stent with ultrasound
- Where
- Denmark
- Volunteers
- 2,500 people
- Sponsor
- Thomas Engstrom
ST Elevation Myocardial Infarction
Fractional Flow Reserve Guided Immediate Versus Staged Complete Myocardial Revascularization in Patients With ST-segment Elevation Myocardial Infarction With Multivessel Disease (Future Study)
It is a prospective, multicenter, randomised controlled, open-label, blinded endpoint assessment trial, to compare the strategy of immediate complete revascularisation and staged complete revascularisation in ST-segment-elevation…
- Trial name
- NCT05967663
- Testing
- PCI-immediate complete revascularisation, PCI-staged complete revascularisation
- Where
- China
- Volunteers
- 840 people
- Sponsor
- RenJi Hospital
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