Clinical trials: ST-elevation Myocardial Infarction (STEMI)
Myocardial Infarction
French Registry of Acute ST-elevation or Non-ST-elevation Myocardial Infarction 2015
Over the last two decades, considerable progress has been made in the management of myocardial infarction, both in the acute phase and in monitoring beyond the hospital phase.
- Trial name
- FASTMI2015 (NCT02566200)
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- French Cardiology Society
ST Elevation Myocardial Infarction, C-Reactive Protein
CRP Apheresis in STEMI
Background: In patients with acute ST-elevation myocardial infarction (STEMI), the amount of infarcted myocardium (infarct size) is known to be a major predictor for adverse remodeling and recurrent adverse cardiovascular events.
- Conditions
- ST Elevation Myocardial Infarction, C-Reactive Protein, Apheresis, Myocardial Injury
- Trial name
- NCT04939805
- Testing
- Selective CRP apheresis using the PentraSorb®-CRP system
- Where
- 5 sites in Austria, Germany
- Volunteers
- 202 people
- Sponsor
- Medical University Innsbruck
ST-Elevation Myocardial Infarction
Can Hypothermia be Incorporated Into Primary Angioplasty for Heart Attack?
The hypothesis of this study is that consciously sedated patients suffering from ST-elevation myocardial infarction can be rapidly and safely cooled to a state of therapeutic hypothermia (32 to 34 degrees C) using the LRS…
- Trial name
- CHIPAHA (NCT00763828)
- Testing
- Life Recovery Systems ThermoSuit
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Life Recovery Systems
Myocardial Ischemia, Myocardial Infarction
Prehospital Evaluation and Economic Analysis of Different Coronary Syndrome Treatment Strategies - PREDICT
Despite remarkable gains in treatment over the last decade short-term mortality for those who survive to hospital with AT-elevation acute myocardial infarction (STEMI) remains high (5%-10%).
- Trial name
- PREDICT (NCT00747656)
- Where
- 5 sites in Canada
- Volunteers
- 446 people
- Sponsor
- St. Joseph's Healthcare Hamilton
STEMI
OCT Guided Magmaris RMS in STEMI
Percutaneous treatment of coronary artery disease depends on the implantation of stents within diseased coronary segments. Compared with conventional bare-metal and drug- eluting stents, which remain permanently within the…
- Trial name
- BESTMAG (NCT03955731)
- Testing
- Magmaris resorbable magnesium scaffold
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
ST Elevation (STEMI) Myocardial Infarction, Non ST Elevation Myocardial Infarction (NSTEMI)
Clinical Characteristics, Frailty, and Prognostic Predictors in Patients Aged 75 and Older With Acute Coronary Syndrome
This study will evaluate clinical characteristics, frailty, and predictors of prognosis in patients aged 75 years and older who are hospitalized with acute coronary syndrome (ACS).
- Conditions
- ST Elevation (STEMI) Myocardial Infarction, Non ST Elevation Myocardial Infarction (NSTEMI), Unstable Angina Pectoris
- Trial name
- NCT07366684
- Testing
- Percutaneous Coronary Intervention (PCI), Conservative Medical Therapy
- Where
- Serbia
- Volunteers
- 550 people
- Sponsor
- Clinical Center Niš
ST-segment Elevation Myocardial Infarction
Thrombus Aspiration in Patients With STEMI
This is a prospective, randomized study with blinded outcome assessment, comparing routine manual thrombus aspiration with no aspiration in patients with acute ST-segment elevation myocardial infarction (STEMI) underwent…
- Trial name
- NCT02606435
- Testing
- percutaneous coronary intervention (PCI), thrombus aspiration
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xijing Hospital
Myocardial Infarction, Angioplasty, Transluminal, Percutaneous Coronary
Efficacy Study of Erythropoietin After Revascularization in Myocardial Infarction (REVIVAL-3)
The purpose of this study is to determine whether erythropoietin is superior to placebo with respect to left ventricular ejection fraction in patients with ST-elevation myocardial infarction undergoing percutaneous coronary…
- Trial name
- REVIVAL-3 (NCT00390832)
- Testing
- Erythropoietin
- Where
- 2 sites in Germany
- Volunteers
- 138 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Anterior Myocardial Infarction, Heart Failure
Effect of Intravenous Metoprolol Combining RIC on Myocardial Protection in STEMI Patients
The main purpose of this study is to compare the myocardial protection effect of intravenous metoprolol combined with remote ischemic conditioning (RIC) and single treatment before reperfusion in Chinese patients with anterior…
- Trial name
- NCT03579914
- Testing
- Metoprolol Injectable Product, Romote Ischemic Conditioning (RIC), Metoprolol & RIC
- Where
- 16 sites in China
- Volunteers
- 1,206 people, healthy volunteers welcome
- Sponsor
- Harbin Medical University
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-III Canada Satellite Registry
For the majority of Coronary Artery Disease (CAD), treatment with Percutaneous Transluminal Coronary Angioplasty (PTCA) provides high initial procedural success.
- Trial name
- NCT01880242
- Where
- 2 sites in Canada
- Volunteers
- 250 people
- Sponsor
- Biotronik Canada Inc
Acute Coronary Syndrome
A Study to Evaluate the Safety of 12 Weeks of Dosing With GW856553 and Its Effects on Inflammatory Markers, Infarct Size, and Cardiac Function in Subjects With Myocardial Infarction Without ST-segment Elevation
This is a randomized, double-blind, placebo-controlled, parallel group, multi-center study to evaluate initial safety and efficacy of GW856553 in subjects with NSTEMI.
- Trial name
- Solstice (NCT00910962)
- Testing
- GW856553
- Where
- 108 sites in United States, Australia and 7 more
- Volunteers
- 526 people
- Sponsor
- GlaxoSmithKline
ST-Elevation Myocardial Infarction
Myocardial Salvage Assessed by Cardiovascular Magnetic Resonance - Impact on Outcome
In acute myocardial infarction cardiovascular magnetic resonance imaging can retrospectively detect the myocardium at risk and the irreversible injury.
- Trial name
- NCT00952224
- Testing
- magnetic resonance imaging
- Where
- Germany
- Volunteers
- 267 people
- Sponsor
- University of Leipzig
ST-elevation Acute Myocardial Infarction, STEMI
Multicenter Registry of Very Early and Late Clinical Outcomes to Everolimus-eluting Cobalt-Chromium Stent In Patients With ST Elevation Myocardial Infarction
To compare early and late clinical outcomes with everolimus-eluting cobalt-chromium stent in patients with ST-elevation acute myocardial infarction, as well as identify the characteristics and efficacy of CoCr-EES.
- Trial name
- XIENCE STEMI (NCT02792920)
- Testing
- CoCr-EES
- Where
- 2 sites in Japan
- Volunteers
- 400 people
- Sponsor
- Hyogo Brain and Heart Center
STEMI
Monocytosis and Culprit Vessel in STEMI Patients
Increased white blood cell count at the onset of an acute ST elevation myocardial infarction has been shown to be associated of increased incidence of heart failure and mortality.
- Trial name
- NCT01569646
- Where
- United States
- Volunteers
- 226 people
- Sponsor
- Northwell Health
STEMI - ST Elevation Myocardial Infarction, NSTEMI - Non-ST Segment Elevation Myocardial Infarction (MI)
Intensive Cholesterol-Lowering Within 24 Hours of PCI Perioperative Period
This project team is conducting a multicenter randomized controlled study, aiming to administer PCSK9 inhibitors subcutaneously as early as possible within 24 hours during the perioperative period of AMI (included <24h STEMI and…
- Trial name
- INCLINE-AMI (NCT07290699)
- Testing
- Recaticimab
- Volunteers
- 2,442 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Myocardial Infarction
The Role of Inflammation in Myocardial Infarction
The aim of this research is to study the prognostic role of a selected combination of cytokines and adipokines in patients with myocardial infarction, as well as to determine their role in the development of adverse cardiac…
- Trial name
- INFINITY (NCT06065514)
- Where
- 4 sites in Cyprus, Greece
- Volunteers
- 100 people
- Sponsor
- Nicosia General Hospital
Myocardial Infarction, Acute Coronary Syndrome
HeartHome: A Nurse-Driven, Home-Based Cardiac Rehabilitation Program
The purpose of this implementation trial is to execute a nurse-led, home-based cardiac rehabilitation (HBCR) program, evaluate the program's impact on patient outcomes over 6 months; and compare outcomes of HeartHome (HH)…
- Conditions
- Myocardial Infarction, Acute Coronary Syndrome, ST-segment Elevation Myocardial Infarction (STEMI), Non-ST-Segment Elevation Myocardial Infarction (NSTEMI)
- Trial name
- NCT04131816
- Testing
- HeartHome
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of North Carolina, Chapel Hill
Acute Myocardial Infarction
Effects of Nitric Oxide for Inhalation in Myocardial Infarction Size
The purpose of this study is to determine the effects of Nitric Oxide for Inhalation on Myocardial Infarction Size.
- Trial name
- NOMI (NCT01398384)
- Testing
- Nitric Oxide, MI size at 48-72 hours
- Where
- 4 sites in Belgium, Hungary and 1 more
- Volunteers
- 250 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Myocardial Infarction
Efficacy and Safety of OPL-0301 Compared to Placebo in Adults With Post-Myocardial Infarction (MI)
Study OPL-0301-201 is intended to generate efficacy and safety data of OPL-0301 in participants with post-myocardial infarction (MI) left ventricular dysfunction (LVD)
- Trial name
- RESTORE (NCT05327855)
- Testing
- OPL-0301 Dose 1, OPL-0301 Dose 2
- Sponsor
- Valo Health, Inc.
ST-elevation Myocardial Infarction, Multivessel Coronary Disease
Timing of Complete Revascularization in Patients With ST-segment Elevation Myocardial Infarction And Multivessel Disease
At present, the two treatment strategies of opening non infarct related arteries (non IRA) simultaneously or by stages after emergency percutaneous coronary intervention (PCI) in patients with acute ST segment elevation…
- Trial name
- TERMINAL (NCT05231226)
- Testing
- Immediately CR, Staged (within 45 days) CR
- Where
- China
- Volunteers
- 426 people
- Sponsor
- Beijing Anzhen Hospital
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