Clinical trials: ST-elevation Myocardial Infarction (STEMI)
Myocardial Infarction
AMI-DC in Patients With Anterior Wall Myocardial Infarction
The purpose of this trial is to assess the safety of AMI-DC treatment. The participants who voluntarily sign the consent form will be screened according to the inclusion/exclusion criteria then allocated either to the…
- Trial name
- AMI-DC (NCT05554484)
- Testing
- Autologous peripheral blood-derived tolerogenic dendritic cells
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- The Catholic University of Korea
Acute ST Segment Elevation Myocardial Infarction, Acute Coronary Syndrome
Comparing Ticagrelor and Clopidogrel Pharmacodynamics After Thrombolysis
This study involves doing platelet function testing in patients who have undergone fibrinolysis. Fibrinolysis (Use of clot busting medicine in heart attack) is the standard of care to restore blood flow in blocked arteries as…
- Trial name
- TACAT (NCT02048085)
- Testing
- Ticagrelor, Clopidogrel
- Where
- United States
- Sponsor
- Medical Center of South Arkansas
ST Elevation Myocardial Infarction, Remodeling, Left Ventricle
Predictors of Adverse Left Ventricular Remodeling and Final Infarct Size After Primary Percutaneous Coronary Intervention for ST Elevation Myocardial Infarction: A Strain Analysis Study Using Echocardiography and Feature Tracking Cardiac Magnetic Resonance
ST-segment elevation myocardial infarction (STEMI) is one of the most important causes of death and disability around the world.
- Trial name
- NCT04773652
- Testing
- speckle tracking echo
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Acute Myocardial Infarction
Paclitaxel Eluting Balloon After Bare Metal Stent Implantation vs. Drug-Eluting Stent in St Elevation Myocardial Infarction
Study objective is the evaluation of safety and efficacy at 12 months of the combination treatment of bare metal Stent plus Paclitaxel Eluting Balloon vs drug eluting stent in patients with ST-elevation myocardial infarction with…
- Trial name
- PEBSI-2 (NCT03610347)
- Testing
- Bare metal Stent plus Paclitaxel Balloon, Drug Eluting Stent
- Where
- 16 sites in Spain
- Volunteers
- 199 people
- Sponsor
- Fundacion Investigacion Interhospitalaria Cardiovascular
STEMI - ST Elevation Myocardial Infarction, Reperfusion Injury, Myocardial
Combination With Treg Levels and CMR to Assess the Severity and Prognosis of Reperfusion Injury After PPCI in STEMI Patients
This study aims to determine whether combination with regulatory T cell (Treg) levels and cardiac magnetic resonance imaging (CMR) are predictive of the severity of reperfusion injury following myocardial infarction and the…
- Trial name
- TregCMRRS (NCT03939338)
- Testing
- Treg levels and CMR results
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Beijing Friendship Hospital
ST Elevation Myocardial Infarction
Shanghai ST-segment Elevation Myocardial Infarction Cohort
ST-segment elevation myocardial infarction(STEMI) remains a major cause of morbidity and mortality worldwide, despite of the early reperfusion therapy, including fibrinolysis, primary percutaneous coronary intervention (PCI),and…
- Trial name
- NCT05450757
- Where
- 7 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Ruijin Hospital
ST Elevation Myocardial Infarction
Cost Effectiveness if Primary PCI Versus Thrombolytic Therapy in Acute STEMI in Assiut University Hospital
Cost effectiveness between PPCI and thrombolytic therapy in STEMI patients without contraindications
- Trial name
- NCT03310437
- Testing
- Primary PCI
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nahed Sameh Zaki
Myocardial Infarction, Acute
Pharmacoinvasive Strategy vs. Primary PCI in STEMI: A Prospective Registry in a Large Geographical Area
For patients presenting with ST-elevation myocardial infarction (STEMI), immediate and timely reperfusion treatment is essential.
- Trial name
- PHASE-MX (NCT03974581)
- Testing
- Primary percutaneous coronary intervention, Pharmacoinvasive strategy
- Where
- Mexico
- Volunteers
- 500 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
ST Elevation Myocardial Infarction
Coronary Physiology Testing in Acute Coronary Syndromes
This is an interventional, prospective, multicenter study (5 IRCCS hospitals belonging to the Italian Cardiology Network) in patients with STEMI treated with successful primary PCI to assess the ability of coronary physiology…
- Trial name
- CoPhyTea (NCT04677257)
- Testing
- PCI, invasive coronary physiology and CMR
- Where
- 5 sites in Italy
- Volunteers
- 130 people
- Sponsor
- IRCCS San Raffaele
Familial Hypercholesterolemia
Familial Hypercolerstremia as Risk Factor in Stemi Patient Who Underwent Ppci
Famulial hypercolerstremia as risk factor
- Trial name
- NCT03900169
- Testing
- Genetic
- Where
- Egypt
- Volunteers
- 2 people
- Sponsor
- Assiut University
Cardiac Arrest
Ischemic Conditioning in STEMI Patients
The purposes of the study are to 1) study alterations in the metabolomic profile of patients exposed to post-ischemic conditions and 2) study alterations in myocardial infarction size of patients exposed to post-ischemic…
- Trial name
- EDICT (NCT03097419)
- Testing
- Remote post-ischemic conditioning
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Beth Israel Deaconess Medical Center
Platelet Reactivity
High (100mg) Versus Standard (60mg) Loading Dose of Prasugrel in Patients With ST-elevation Myocardial Infarction (STEMI), Undergoing Primary Percutaneous Coronary Intervention (PCI)
This is a prospective, multi-center, non-randomized, controlled study in 2 sequential groups of P2Y12 inhibitor-naive consecutive STEMI patients undergoing primary PCI.
- Trial name
- NCT01835353
- Testing
- Prasugrel 100mg loading dose, Prasugrel 60mg loading dose
- Where
- Greece
- Volunteers
- 82 people
- Sponsor
- University of Patras
Myocardial Infarction, Acute Coronary Syndrome
Identification of Risk Factors for Acute Coronary Events by OCT After STEMI and NSTEMI in Patients With Residual Non-flow Limiting Lesions
The objective of this study is to compare the clinical outcome of Non-ST-elevation myocardial infarction (NSTEMI) and ST-elevation myocardial infarction (STEMI) patients with non-obstructive, non-culprit coronary lesions and…
- Conditions
- Myocardial Infarction, Acute Coronary Syndrome, Coronary Artery Disease
- Trial name
- PECTUS-obs (NCT03857971)
- Testing
- Coronary Optical Coherence tomography
- Where
- Netherlands
- Volunteers
- 438 people
- Sponsor
- Radboud University Medical Center
ST Elevation (STEMI) Myocardial Infarction
Bempedoic Acid in PPCI Impact on Clinical Outcome and Inflammatory Markers
Bempedoic acid in PPCI
- Trial name
- NCT07129850
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Subacute Myocardial Infarction
Study to Assess Safety & Effects of Autologous ADSCs During Recovery Phase of ST-Elevation MI Effects of Autologous ADSC Implantation During Subacute Recovery Phase of ST-Elevation Myocardial Infarction
The intent of this clinical study is to answer the questions: 1) Is the proposed treatment safe? and 2) Is treatment effective in improving cardiac function and clinical outcomes?
- Trial name
- NCT03272191
- Testing
- Liposuction and stem cell implantation
- Where
- United States
- Sponsor
- Ageless Regenerative Institute
Myocardial Infarction
Safety of KAI-9803 for Injection With Angioplasty Following Heart Attack
Restoring blood flow to coronary arteries as quickly as possible is the best way to reduce the damage to the muscle that occurs with a heart attack.
- Trial name
- NCT00093197
- Testing
- KAI-9803 for Injection
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- KAI Pharmaceuticals
Stable Angina, Unstable Angina
Atorvastatin for Reduction of Myocardial Damage During Angiography and Its Mechanism Associated With IMR
The purpose of this study is to determine whether preoperative loading dose atorvastatin can prevent perioperative myocardial infarction during angiography and main adverse cardiac events 1 month after operation in stable angina…
- Conditions
- Stable Angina, Unstable Angina, Acute Non-ST-segment Elevation Myocardial Infarction
- Trial name
- ARMYDA-IMR (NCT01761656)
- Testing
- loading dose atorvastatin, conventional dose atorvastatin
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Central South University
Myocardial Infarction
Comparison of Primary PCI vs. Post-thrombolysis PCI as Reperfusion Strategies in STEMI
The conceptual hypothesis of this study is that primary angioplasty is superior to a combined strategy of immediate thrombolysis followed by routine angioplasty in patients with ST-segment elevation acute myocardial infarction…
- Trial name
- GRACIA4 (NCT02268669)
- Testing
- Reperfusion strategies
- Volunteers
- 1,444 people
- Sponsor
- GRACIA Group
Infarction, Myocardial
Efficacy Of Eptifibatide Compared To Abciximab In Primary Percutaneous Coronary Intervention (PCI) For Acute ST Elevation Myocardial Infarction (STEMI)
Multinational, multicentre, randomised, prospective, open, parallel group study directly comparing two glycoprotein-IIb/IIIa inhibitors, abciximab and eptifibatide, added early to standard treatment before primary PCI of STEMI…
- Trial name
- NCT00426751
- Testing
- Abciximab, Eptifibatide
- Where
- 24 sites in France, Germany
- Volunteers
- 429 people
- Sponsor
- GlaxoSmithKline
ST-elevation Myocardial Infarction
Standard (180mg) Versus Double (360mg) Loading Dose of Ticagrelor in Patients With ST-elevation Myocardial Infarction (STEMI), Undergoing Primary Percutaneous Coronary Intervention (PCI)
This is a multi-center, prospective, randomized, single-blind, investigator initiated, pharmacodynamic study of parallel design, performed at 3 institutions (Patras University Hospital; Evangelismos Athens General Hospital…
- Trial name
- NCT01575795
- Testing
- Ticagrelor
- Where
- Greece
- Volunteers
- 83 people
- Sponsor
- University of Patras
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