Clinical trials: STDs
Risk Reduction Behavior, Interpersonal Relations
A Community-health Worker Delivered HIV/STI Prevention Intervention for Internally Displaced Women in Leogane, Haiti
The investigators will develop, deliver and evaluate a solar powered tablet-based individual and group focused HIV/STI prevention intervention with internally displaced women in Leogane, Haiti.
- Conditions
- Risk Reduction Behavior, Interpersonal Relations, Mental Disorders
- Trial name
- FASY (NCT01492829)
- Testing
- individual and group-based, community health worker delivered
- Where
- Haiti
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Women's College Hospital
Gonorrhea, Chlamydia Infections
Risk Assessment of Long-Haul Truck Drivers
International studies have repeatedly documented a substantial prevalence of sexual risk behaviors and high rates of human immunodeficiency virus (HIV) and other sexually transmitted infections (STI) ranging from 5%-56% amongst…
- Conditions
- Gonorrhea, Chlamydia Infections, Hepatitis B, Hepatitis C
- Trial name
- NCT00381992
- Where
- United States
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Neisseria Gonorrhoeae Infection, Chlamydia Trachomatis Infection
Outcomes From Point-of-Care Sexually Transmitted Infection (STI) Testing in an Urban Sexual Health Clinic: A Randomized Trial
The goal of this clinical trial is to learn about the impact of a point-of-care test for gonorrhea and chlamydia in people without symptoms who are seeking sexually transmitted infection testing.
- Trial name
- NCT07399873
- Testing
- Point-of-care assay for chlamydia and gonorrhea, Laboratory-based chlamydia and gonorrhea NAAT, CRISPR-based assay
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
HIV Infections
A New APPROACH to HIV Testing: Adaptation of POCT for Pharmacies to Reduce Risk and Optimize Access to Care in HIV
An estimated 21% of Canadians with HIV are unaware of their infection. There is a need to improve access to HIV testing to detect infections earlier so individuals can access care early and take steps to prevent transmission to…
- Trial name
- APPROACH (NCT03210701)
- Testing
- A HIV POCT program adapted for & provided by community pharmacists
- Where
- Canada
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Cancer of Cervix, HPV Infection
The Effect of Education Given to Women on Cervical Cancer on Knowledge, Attitude and Belief
Aim: The aim of this study is to reveal the effect of education given to women about cervical cancer on knowledge, attitude and belief.
- Trial name
- EEWCCKAB (NCT05990270)
- Testing
- education
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
HIV-I, Human Immunodeficiency Virus Type 1
Oral ISL QM as PrEP in Cisgender Women at High Risk for HIV-1 Infection (MK-8591-022)
This study will evaluate whether oral islatravir (ISL) is effective in preventing Human Immunodeficiency Virus Type 1 (HIV-1) infection in women at high-risk for HIV-1 infection.
- Conditions
- HIV-I, Human Immunodeficiency Virus Type 1, Prophylaxis
- Trial name
- Impower-022 (NCT04644029)
- Testing
- Islatravir, FTC/TDF
- Where
- 24 sites in United States, South Africa and 1 more
- Volunteers
- 730 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Bacterial Vaginosis, HIV Infections
Effect of Bacterial Vaginosis on HIV Susceptibility and Female Genital Immunology
A non-randomized, interventional, longitudinal clinical study to quantify the impact of bacterial vaginosis treatment on HIV susceptibility and genital immunology in Kenyan women.
- Trial name
- NCT02527941
- Testing
- Metronidazole
- Where
- Kenya
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Tuberculosis, Tuberculosis (TB)
Questioning the Epidemiology of Asymptomatic TB
Tuberculosis (TB) remains one of the world's leading causes of morbidity and mortality. Current TB control strategies focus largely on the binary paradigm of TB, which tackle Mtb infection and the symptomatic stages of the…
- Conditions
- Tuberculosis, Tuberculosis (TB), HIV, HIV (Human Immunodeficiency Virus)
- Trial name
- TB QUEST (NCT07312266)
- Where
- Mozambique
- Volunteers
- 6,770 people, healthy volunteers welcome
- Sponsor
- Barcelona Institute for Global Health
Chlamydia Trachomatis Infection, Neisseria Gonorrhoeae Infection
Optimizing Antibiotic Prescription in STI Clinics Using Rapid POCT
Sexually transmitted infections (STIs) caused by Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) are increasing in France, with a significant proportion of asymptomatic infections.
- Conditions
- Chlamydia Trachomatis Infection, Neisseria Gonorrhoeae Infection, Sexually Transmitted Infections, Antimicrobial Resistance / Antibiotic Overuse
- Trial name
- OPTIMISE (NCT07884656)
- Testing
- cobas® Liat® CT/NG Point-of-Care Test
- Where
- 2 sites in France
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Cervical Cancers, Vulvar Cancers
A Study of V503, a 9-valent Human Papillomavirus (9vHPV) Vaccine in Females 12-26 Years of Age Who Have Previously Received GARDASIL™ (V503-006)
This study will evaluate whether V503 (9vHPV vaccine), is well tolerated in girls and women between 12 and 26 years old who have previously been vaccinated with GARDASIL™.
- Conditions
- Cervical Cancers, Vulvar Cancers, Vaginal Cancers, Genital Warts
- Trial name
- NCT01047345
- Testing
- V503
- Volunteers
- 924 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
HIV Infections, Opioid-Related Disorders
Drug Treatment Combined With Drug and Risk Reduction Counseling to Prevent of HIV Infection and Death Among Injection Drug Users
Drug abuse and HIV/AIDS are serious global health problems. Injection drug use is currently the major mode of transmission of HIV in many countries.
- Trial name
- NCT00270257
- Testing
- Buprenorphine/Naloxone
- Where
- 4 sites in China, Thailand
- Volunteers
- 1,251 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Hiv
Impact of Antiretroviral Treatment on Pharmacokinetics and Pharmacodynamics of Thienopyridines in Healthy Volunteers and HIV Patients
HIV patients are at particular risk to develop cardiovascular disease (CVD) as they exhibit multiple risk factors by the nature of their pathology.
- Trial name
- IMPACT/R (NCT03054207)
- Testing
- Clopidogrel 300Mg Tablet, Prasugrel 60Mg
- Where
- Switzerland
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Jules Desmeules
Hiv, Chlamydia
Randomized Trial of an HIV Prevention and Relationship Education Program for Young Male Couples
Young gay, bisexual, and other men who have sex with men (YMSM) are the only risk group in which rates of new HIV infections are on the rise.
- Conditions
- Hiv, Chlamydia, Gonorrhea, Relation, Interpersonal
- Trial name
- 2GETHER (NCT03186534)
- Testing
- 2GETHER, Positive Affect Enhancement
- Where
- United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Syphilis
Azithromycin/Bicillin Syphilis
The purpose of this study is to determine if azithromycin, a drug approved for treatment of other infections, is as effective for syphilis (a sexually transmitted disease) as the standard treatment.
- Trial name
- NCT00031499
- Testing
- Azithromycin, Benzathine Penicillin, Doxycycline
- Where
- 10 sites in United States, Madagascar
- Volunteers
- 593 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Seropositive
Study of Vitamin D Supplementation to Male HIV Sero-positive Patients
The investigators want to investigate if HIV sero-positive males benefit from vitamin D supplementation. The study runs in 16 weeks and the participants are treated with one of three placebo controlled regimes (tablets): 1.
- Trial name
- NCT00990678
- Testing
- Rocaltrol, Vitamin D, Calcium
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
HIV Infections
Entre Herman@s: Promoting Health Among Latino MSM
This is a randomized controlled trial with an attention placebo control group. The goal of this study is to decrease HIV incidence in Latino men who have sex with men by engaging their siblings in PrEP-use promotion.
- Trial name
- NCT05805306
- Testing
- Entre Herman@s, Vaccines for Health
- Where
- United States
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
HIV Infections, Pneumococcal Infections
Safety of and Immune Response to a Pneumococcal Vaccine (PncCV) in HIV Infected and Uninfected Children
Infection by Streptococcal pneumoniae is a common invasive bacterial infection in HIV infected children. The purpose of this study is to determine the safety of and immune response to a pneumococcal polysaccharide-protein…
- Trial name
- NCT00099658
- Testing
- Pneumococcal polysaccharide-protein conjugate vaccine
- Volunteers
- 579 people, healthy volunteers welcome
- Sponsor
- CIPRA SA
HIV/AIDS Prevention
Effects of an HIV Intervention Among Sex Workers in the Philippines
This study will implement a socio-behavioral intervention in Quezon City, the Philippines, using a community-based participatory approach.
- Trial name
- NCT02071264
- Testing
- HIV/STI intervention
- Where
- Philippines
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lianne Urada
HIV Infections, Sexually Transmitted Diseases
HORIZONS HIV Intervention
The Horizons Program will test the efficacy of a multi-session HIV prevention program for African American female teens attending reproductive health clinics in Atlanta, GA.
- Trial name
- HORIZONS (NCT00633906)
- Testing
- HORIZONS HIV Intervention, enhanced standard-of-care
- Where
- 3 sites in United States
- Volunteers
- 715 people, healthy volunteers welcome
- Sponsor
- Emory University
Human Immunodeficiency Virus
Problems With Immune Recovery in the Gut Tissue
The aim of this study is to find out if the process of HIV replication in the lymph tissue and gut tissue of people taking HIV drugs causes long-term damage to the ability of the gut to protect you from other infections and…
- Trial name
- NCT01460433
- Testing
- Genital and rectal swabbing
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
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