Clinical trials: Sacrocolpopexy
Pelvic Organ Prolapse
Comparison of the Efficacy of Sacrocolpopexy, the Amreich-Richter Procedure and Transvaginal Mesh
Pelvic organ prolapse, POP, is a common health problem affecting up to 40% of women. Very little is known about the factors associated with surgical failure.
- Trial name
- SAME (NCT03053479)
- Testing
- Laparoscopic sacrocolpopexy, Transvaginal mesh procedure, Amreich-Richter procedure
- Where
- 7 sites in Czechia, Slovakia
- Volunteers
- 462 people
- Sponsor
- Charles University, Czech Republic
Urogenital Prolapse
LAparoscopic Preventive PRErectal Mesh
Urogenital prolapse is a frequent and invalidating pathology in women, involving the anterior vaginal wall and the uterus in most cases. Posterior vaginal wall prolapse is present in only 50% of cases.
- Trial name
- LAPREM (NCT03766048)
- Testing
- Single-Anterior-Mesh, SAM, Double-Mesh, DM
- Where
- 9 sites in France
- Volunteers
- 834 people
- Sponsor
- University Hospital, Lille
Stress Urinary Incontinence, Pelvic Floor Disorders
Single-incision Versus Retropubic Mid-Urethral Sling (Solyx) for SUI During Minimally Invasive Sacrocolpopexy
SASS (Single-incision Versus Retropubic Mid-Urethral Sling (Solyx) for SUI During Minimally Invasive Sacrocolpopexy) will be a multicenter, prospective, randomized, single-blind non-inferiority trial.
- Trial name
- SASS (NCT04586166)
- Testing
- RP Sling, SIS
- Where
- 5 sites in United States
- Volunteers
- 180 people
- Sponsor
- Wake Forest University Health Sciences
Pelvic Organ Prolapse, Constipation
Cohort Study of Bowel Function Following Robotic-assisted Laparoscopic Sacrocolpopexy
Compare changes in bowel function before, 6 months and one year after Robotic-assisted laparoscopic sacral colpopexy. Compare objective anatomic outcomes before, 6 months and one year after Robotic-assisted laparoscopic sacral…
- Conditions
- Pelvic Organ Prolapse, Constipation, Bowel Dysfunction, Irritable Bowel Syndrome
- Trial name
- NCT01618292
- Testing
- Robotic sacral colpopexy
- Where
- United States
- Volunteers
- 393 people
- Sponsor
- Atlantic Health System
Laparoscopic Hysterectomy and/or Laparoscopic Sacrocolpopexy
Mechanical Bowel Preparation Before Laparoscopic Hysterectomy and Laparoscopic Sacrocolpopexy: a Randomized Controlled Trial
The purpose of this study is to learn about bowel preparation (cleansing) before laparoscopic hysterectomy and/or sacrocolpopexy.
- Trial name
- NCT01576965
- Testing
- Fleet Enema (sodium biphosphate and sodium phosphate)
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of North Carolina, Chapel Hill
Stress Urinary Incontinence (SUI)
Single Incision Suburethral Sling at Time of Robotic Sacrocolpopexy
This study was designed to evaluate urinary function before and one year after single incision sling placement at the time of robotic sacrocolpopexy.
- Trial name
- NCT01982188
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Atlantic Health System
Prolapse, Urinary Incontinence
Long-term Effectiveness of Abdominal Sacrocolpopexy for the Treatment of Pelvic Organ Prolapse
The Colpopexy and Urinary Reduction Effort (CARE) trial is a research study designed to evaluate whether the addition of a second surgical procedure in addition to a procedure for female pelvic organ prolapse (POP) affects the…
- Trial name
- E-CARE (NCT00099372)
- Where
- 8 sites in United States
- Volunteers
- 215 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Vaginal Vault Prolapse
Laparoscopic Sacrocolpopexy: Long Term Follow-up
The purpose of this study is to determine the long term results of laparoscopic sacrocolpopexy regarding anatomical results, recurrences, complications, further surgeries required, patients satisfaction and quality of life.
- Trial name
- NCT01394237
- Testing
- Examination
- Where
- Switzerland
- Volunteers
- 75 people
- Sponsor
- Kantonsspital Aarau
Stress Incontinence Female, Pelvic Organ Prolapse
Sequence of Midurethral Sling Placement During Robotic Sacrocolpopexy
This study looks at the best time to place a midurethral sling (MUS), which is a small piece of mesh used to treat stress urinary incontinence (SUI) (leaking urine when you cough, laugh, or exercise).
- Trial name
- NCT07008898
- Testing
- Midurethral sling placed before robotic sacrocolpopexy, Midurethral sling placed after robotic sacrocolpopexy
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- University of Alabama at Birmingham
Pelvic Organ Prolapse
Analysis of Procedural Times Using Colpassist for Robotic-Assisted Sacrocolpopexy; a Randomized Controlled Trial
The purpose of this study is to evaluate the efficiency of the Colpassist vaginal positioning device during robotic-assisted sacrocolpopexy.
- Trial name
- ACRAS (NCT02367235)
- Testing
- Traditional vaginal positioning device, Colpassist vaginal positioning device
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of North Carolina, Chapel Hill
Pelvic Organ Prolapse
Total Laparoscopic Hysterectomy With Sacrocolpopexy Versus Total Laparoscopic Hysterectomy With Lateral Suspension in Patients With Pelvic Organ Prolapse
This prospective randomized surgical trial is designed to compare objective and subjective outcomes of total laparoscopic hysterectomy with sacrocolpopexy versus total laparoscopic hysterectomy with lateral suspension for the…
- Trial name
- NCT03722563
- Testing
- total laparoscopic hysterectomy with sacrocolpopexy, total laparoscopic hysterectomy with lateral suspension
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Antalya Training and Research Hospital
Pelvic Organ Prolapse
Pain After Insufflation for Robotic Sacrocolpopexy (PAIRS) Trial
This study evaluates post-operative pain between different insufflation pressures during robotic-assisted sacrocolpopexy. Subjective pain and narcotic usage after surgery will be measured.
- Trial name
- NCT04858438
- Testing
- Insufflation during surgery
- Where
- United States
- Sponsor
- Henry Ford Health System
Pelvic Organ Prolapse, Cystocele
SCP vs HUSLS for Pelvic Organ Prolapse Repair
The purpose of this study is to compare the effectiveness of R-SCP versus HUSLS for treatment of pelvic organ prolapse.
- Conditions
- Pelvic Organ Prolapse, Cystocele, Rectocele, Enterocele
- Trial name
- NCT02800512
- Testing
- Robotic sacrocolpopexy, high uterosacral ligament suspension
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Loma Linda University
Pelvic Organ Prolapse
Robotic-assisted Laparoscopic Sacrocolpopexy
Robotic-assisted Abdominal Sacrocolpopexy is both a feasible and safe method for apical prolapse repair of the vagina.
- Trial name
- NCT00581334
- Testing
- Robotic-assisted laparoscopic sacrocolpopexy, Open sacrocolpopexy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Irvine
Pelvic Organ Prolapse, Post Operative Pain
Postoperative Pain Management Following Robotic Assisted Sacrocolpopexy
In the effort to reduce postoperative opioid use, there has been increasing interest in developing multimodal pain regimens to better manage postoperative pain while minimizing opioid use and their subsequent side effects that…
- Trial name
- NCT06309693
- Testing
- Quadratus Lumborum (QL) Block, Enhanced Recovery After Surgical (ERAS) Protocol
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Alabama at Birmingham
Uterine Prolapse
Patient-Centered Outcomes in the Surgical Treatment of Uterovaginal Prolapse
The purpose of this study is to compare two types of surgery for the treatment of uterovaginal prolapse to determine which surgery works best from a patient's perspective and has the lowest number of short-term and long-term…
- Trial name
- PREMIER (NCT05063331)
- Testing
- Minimally invasive supracervical hysterectomy and sacrocolpopexy (MI-SCH+SCP), Vaginal hysterectomy with uterosacral ligament suspension (TVH+USLS)
- Where
- 7 sites in United States
- Volunteers
- 300 people
- Sponsor
- University Hospitals Cleveland Medical Center
Constipation by Outlet Obstruction, Pelvic Organ Prolapse
Early Safety of Resection Rectopexy and Sacrocolpopexy
Obstructive defecation syndrome (ODS) defines a disturbed defecation process frequently associated with pelvic organ prolapse (POP) in women.
- Conditions
- Constipation by Outlet Obstruction, Pelvic Organ Prolapse, Urinary Incontinence
- Trial name
- RRPSCPcomb (NCT05910021)
- Where
- Germany
- Volunteers
- 35 people
- Sponsor
- Evangelisches Klinikum Köln Weyertal gGmbH
Prolapse
Operative Time During the Use of the Synthetic Glue IFABONDTM in Laparoscopic Sacrocolpopexy
Laparoscopic sacrocolpopexy has now become the gold standard technique for correction of anterior and apical prolapse. In order to provide an alternative to stapling system and sutures involving vaginal erosion and shrinkage…
- Trial name
- Procolle 2 (NCT03307824)
- Testing
- Synthetic glue IfabondTM, Glue-Free Suture Technique
- Where
- France
- Volunteers
- 54 people
- Sponsor
- Hospices Civils de Lyon
Pelvic Organ Prolapse, Urinary Tract Infections
Study to Assess Duration of Indwelling Catheter After Sacrocolpopexy
Objectives The objective of this study is to help identify the best practice regarding the use of indwelling catheter after minimally invasive urogynecologic surgery.
- Conditions
- Pelvic Organ Prolapse, Urinary Tract Infections, Urinary Retention
- Trial name
- CARESS (NCT02189291)
- Testing
- Immediate catheter removal, Post op day 1 catheter removal
- Where
- 3 sites in United States
- Volunteers
- 72 people
- Sponsor
- Oregon Health and Science University
Prolapse
Affixing Polypropylene Mesh Using Barbed Suture (Quill™ Srs) During Laparoscopic Sacrocolpopexy Randomized Controlled Trial (Quill Lsc)
1.0 STUDY OBJECTIVE 1.1 PRIMARY OBJECTIVE - To compare two methods of polypropylene mesh attachment during laparoscopic sacrocolpopexy (LSC): running technique using self-anchoring 1 barbed delayed absorbable suture (Quill™ SRS…
- Trial name
- QUILL-LSC (NCT01551992)
- Testing
- Quill suture vs. Interrupted suture
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente