Clinical trials: Safe Sex
Hiv
Evaluation of the Preventing AIDS Through Live Movement and Sound (PALMS) Intervention for Minority Adolescents
The purpose of this program evaluation is to determine whether the Preventing AIDS Through Live Movement and Sound (PALMS) group-level intervention is effective in reducing HIV sex risk behaviors and increasing HIV testing of…
- Trial name
- NCT00137644
- Testing
- Preventing AIDS Through Live Movement and Sound (PALMS)
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Gender-based Violence
Addressing School-related Gender-based Violence as Part of the Keeping Girls in School Initiative in Zambia
The objective of this mixed-methods study is to evaluate the effectiveness of a school-based safe-space program delivered to secondary school students in Zambia.
- Trial name
- NCT05839457
- Testing
- Empowerment Pilot
- Where
- Zambia
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- World Bank
HIV Infections, Herpes Genitalis
Effect of Male Circumcision on HIV Incidence (ANRS 1265)
Observational studies suggest that male circumcision may provide protection against HIV-1 infection. A randomized, controlled, intervention trial was conducted in a general population of South Africa to test this hypothesis.
- Conditions
- HIV Infections, Herpes Genitalis, Venereal Diseases
- Trial name
- NCT00122525
- Testing
- Male Circumcision
- Where
- South Africa
- Volunteers
- 3,274 people, healthy volunteers welcome
- Sponsor
- French National Agency for Research on AIDS and Viral Hepatitis
Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men
A Study to Learn How Safe Elinzanetant is, How it Affects the Body, and How it Moves Into, Through and Out of the Body After Single and Multiple Doses in Japanese Healthy Female Adults
Researchers are looking for a new way to treat women who have symptoms that are caused by the sex hormonal changes that happen when a woman's body is going through the menopause.
- Trial name
- NCT04981431
- Testing
- Elinzanetant (BAY3427080)
- Where
- Japan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Bayer
Heart Failure
A Trial to Learn How Safe Vericiguat (BAY1021189) is and the Way the Body Absorbs, Distributes and Gets Rid of Vericiguat in Participants With Kidney Disease and in Age-, Weight- and Gender-matched Healthy Participants
Vericiguat (BAY1021189) is under development to treat heart failure, a condition in in which the heart has trouble pumping blood through the body.
- Trial name
- NCT04722484
- Testing
- Vericiguat (BAY1021189)
- Where
- Germany
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Bayer
Worsening Chronic Heart Failure, Chronic Kidney Disease
A Study to Learn How BAY94-8862 Moves Into, Through and Out of the Body, How Safe it is and How it Affects the Body in Adult Participants With Reduced Kidney Function and in Healthy Participants With Similar Age, Weight and Gender Distribution
Researchers are looking for a better way to treat people who have worsening of chronic heart failure, a long-term condition where the heart does not pump blood as well as it should.
- Trial name
- NCT04908436
- Testing
- Finerenone (BAY94-8862)
- Where
- Germany
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bayer
Risk Behavior, Sex, Unsafe
BEing Safe in Treatment
Prior research has shown that many individuals with substance use disorders engage in HIV/sexual risk behaviors, and could strongly benefit from HIV prevention interventions that were delivered as part of their substance abuse…
- Conditions
- Risk Behavior, Sex, Unsafe, Substance Use, Risk Reduction
- Trial name
- BEST (NCT03575585)
- Testing
- BEST assessment only, BEST assessment plus feedback report, Standard Counselor Training
- Volunteers
- 537 people, healthy volunteers welcome
- Sponsor
- University of Washington
Attitude, Sexual Behavior
Theater in School Sex Education - a Randomized Controlled Study
The study evaluated if interactive theater in school sex education affects student knowledge, attitudes and behavior regarding condom use.
- Conditions
- Attitude, Sexual Behavior, Condom Use, Prevention
- Trial name
- NCT03374696
- Testing
- SAFETY, Standard education
- Volunteers
- 826 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Sexually Transmitted Diseases, Safe Sex
P3 (Prepared, Protected, emPowered)
P3 (Prepared, Protected, emPowered) is an interactive smartphone app for HIV-uninfected YMSM and YTW that utilizes social networking and game-based mechanics as well as a comprehensive understanding of what constitutes "best…
- Conditions
- Sexually Transmitted Diseases, Safe Sex, Adherence, Medication
- Trial name
- P3 (NCT03320512)
- Testing
- P3, P3+, Control
- Where
- 9 sites in United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV Infections
Effectiveness of a Cell Phone-Based Program for Abstinence and HIV Risk Prevention
This study will develop and test the effectiveness of a cell phone-based text messaging program to encourage abstinence, monogamy, or condom use among black urban males in Philadelphia, Pennsylvania.
- Trial name
- NCT00601237
- Testing
- HIV-related text messaging, Nutrition-related text messaging
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
HIV Infections, Substance Use
Reducing HIV: Safer Sex Skill Building in Pregnant Drug Abusing Women
This study will examine safer sex skills building (SSB), a targeted behavioral HIV prevention and risk reduction group intervention in two samples of pregnant drug abusing women.
- Trial name
- NCT00619320
- Testing
- Safer Sex Skills Building (SSB)
- Where
- 2 sites in United States
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Congestive Heart Failure, Renal Impairment
A Study to Learn How the Study Treatment BAY1753011 Moves Into, Through and Out of the Body, How it Works, How Safe it is, and How it Affects the Body When Given Once as Tablet in Male and Female Participants With Reduced Kidney Function Compared to Matched Participants With Normal Kidney Function
Researchers are looking for a better way to treat people with heart failure. Heart failure is a condition which occurs when the heart does not pump blood as well as it should leading to shortness of breath, tiredness, and ankle…
- Trial name
- NCT05599997
- Testing
- Pecavaptan (BAY1753011)
- Where
- 2 sites in Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bayer
Sexual and Reproductive Health and Rights, Violence Against Women and Girls
Right to Health and Freedom From Violence
Bangladesh has the earliest patterns of marriage in the current developing world, high adolescent fertility and high rates of spousal violence against women and girls.
- Trial name
- SAFE (NCT03280680)
- Testing
- Female+male group sessions, Female group sessions, No group sessions
- Volunteers
- 11,340 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
HIV Infections
Project POWER, Adapting Project SAFE: Reducing STD/HIV Risk in Women Prisoners
Project POWER will test the efficacy of a multi-session HIV Prevention program, adapted from an existing program (Project SAFE), for incarcerated women in the rural South.
- Trial name
- POWER (NCT01111721)
- Testing
- Project POWER HIV Risk-reduction Intervention, NC DOC Standard of Care for STIs
- Where
- 2 sites in United States
- Volunteers
- 598 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Gender-Based Violence
Investigating the Barriers and Possibilities for Improving the Healthcare Service of Female Survivors of Gender-based Violence in Upper Egypt
Female survivors of gender-based violence in Upper Egypt need improvement in healthcare services, since women are affected by it more than males.
- Trial name
- NCT07544316
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assiut University
HIV Infections, HIV Seronegativity
A Study to See Whether Two HIV Vaccines Are Safe and Can Prevent HIV Infection
The purpose of this study is to see whether an HIV vaccine, ALVAC vCP205, is safe and can prevent HIV infection. The vCP205 vaccine will be tested with another vaccine, gp160MN/LAI-2.
- Trial name
- NCT00004579
- Testing
- gp160 MN/LAI-2, ALVAC-HIV MN120TMG (vCP205)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Walter Reed Army Institute of Research (WRAIR)
HIV Infections, AIDS
Efficacy Study of the Vaginal Gel Carraguard to Prevent HIV Transmission
The purposes of this study are to determine whether Carraguard® Gel can prevent the transmission of HIV when used during vaginal intercourse, and to confirm that the gel is safe for vaginal use.
- Conditions
- HIV Infections, AIDS, Sexually Transmitted Diseases, HIV Seroconversion
- Trial name
- NCT00213083
- Testing
- Carraguard (PC-515)
- Where
- 3 sites in South Africa
- Volunteers
- 6,203 people, healthy volunteers welcome
- Sponsor
- Population Council
Knowledge Level
Effect of Peer Education on Reproductive Health and Safe Sexuality Knowledge
The aim of this study is to examine the effect of Safe Sexuality and Family Planning Education with Peer Education on Midwifery Students, to create awareness on this issue and to contribute to the literature.
- Trial name
- NCT07120919
- Testing
- Peer Educatıon
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medipol University
HIV Infections
Evaluation of the Extension at Community Level of Safe Male Circumcision (ANRS 12126 ORANGE FARM 2)
This study is aimed at demonstrating whether or not Male Circumcision can be used as an effective public health prevention tool that will have an impact on HIV prevalence in the South African population.
- Trial name
- ORANGE FARM 2 (NCT00623051)
- Testing
- Male Circumcision
- Where
- South Africa
- Volunteers
- 27,000 people, healthy volunteers welcome
- Sponsor
- French National Agency for Research on AIDS and Viral Hepatitis
Human Immunodeficiency Virus Exposure, Alcohol; Harmful Use
Game Plan for PrEP
This small pilot randomized controlled trial will test whether a brief, web-based intervention inspired by the principles of motivational interviewing helps high-risk men who take pre-exposure prophylaxis (PrEP) moderate their…
- Trial name
- NCT04973267
- Testing
- Game Plan for PrEP, Attention-Matched Control Lifestyle Habits Videos
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Brown University