Clinical trials: Safety and Tolerability in Healthy Subjects
Safety and Tolerability, Healthy Volunteers
Phase 1 Study to Evaluate Safety, Tolerability and Pharmacokinetics/-Dynamics of AK1967 (Procizumab)
Dipeptidyl peptidase 3 (DPP3) is a protease involved in the degradation of several cardiovascular mediators. During cardiogenic shock, upregulation of the vasoconstrictive molecule angiotensin II is a physiologic and potentially…
- Trial name
- NCT06331884
- Testing
- AK1967 (Procizumab)
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- 4TEEN4 Pharmaceuticals GmbH
Safety and Tolerability of EGT0001474 in Healthy Volunteers
Study to Determine the Safety, Tolerability, and Pharmacokinetic (PK) Profile of EGT0001474 in Healthy Volunteers
This study evaluated the safety, tolerability and pharmacokinetics of single or multiple doses of EGT0001474.
- Trial name
- NCT00854113
- Testing
- EGT0001474
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Theracos
Safety, Tolerability
A Single Ascending Dose Study To Assess The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of AZD9567.
This is a Phase I, first-in-human (FIH), randomized, single-blind, placebo-controlled, single ascending dose sequential group study in healthy male subjects.
- Conditions
- Safety, Tolerability, Pharmacokinetics, Pharmacodynamics
- Trial name
- NCT02512575
- Testing
- AZD9567 Monohydrat, Prednisolone
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Safety, Tolerability
A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD9977 After Single Ascending Doses to Healthy Males
This study will be a randomized, single-blind, placebo-controlled first-in-human study in healthy male subjects to assess the safety, tolerability and pharmacokinetics of single ascending doses of AZD9977.
- Conditions
- Safety, Tolerability, Pharmacokinetics, Healthy Subjects
- Trial name
- NCT02484729
- Testing
- AZD9977, oral suspension, AZD9977, oral solution
- Where
- United Kingdom
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- AstraZeneca