Clinical trials: Safety of Intervention
Hair Fall and Pre-mature Graying
Proof-of-Science, Prospective, Interventional, Three-arm, Double-Blind, Randomized, Safety and Efficacy Real World Evidence Study.
This is proof-of-science, prospective, interventional, three-arm, double-blind, randomized, safety and efficacy real world evidence study of herbal and non herbal formulations in healthy human subjects having complaint of hair…
- Trial name
- NCT06552039
- Testing
- Polyherbal Hair Oil, Minoxidil Herbal Hair Oil + Minoxidil 5 (%) Hair Serum, Minoxidil Hair Serum
- Where
- India
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Osteoporosis
HDDO-1614 Intervention Trial
Randomized, Open-label, Single-dose, 3-period, 6-sequence, 3-way crossover Study
- Trial name
- NCT03234244
- Testing
- Bazedoxifene 20 mg, Cholecalciferol, Bazedoxifene 20mg and Cholecalciferol
- Where
- South Korea
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Hyundai Pharmaceutical Co., LTD.
Complication of Surgical Procedure
Testing the Efficacy and Safety of the WEI Nasal Jet
Testing the efficacy and safety of the WEI Nasal Jet.
- Trial name
- WNJ (NCT02005406)
- Testing
- Experimental group and control groupl
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Zeyong Yang
Rabies
Clinical Trial of Freeze-dried Human Rabies Vaccine (Without Serum Vero Cells)
This study was intended to explore the safety and immunogenicity of the test vaccine compared to the control vaccine. The trial consisted of two phases. Phase I used an open-ended design.
- Trial name
- NCT05969626
- Testing
- 5-dose group of test vaccine, 5-dose group of control vaccine, 4-dose A group of test vaccine
- Where
- 4 sites in China
- Volunteers
- 2,460 people, healthy volunteers welcome
- Sponsor
- Ningbo Rongan Biological Pharmaceutical Co., Ltd.
Dermal Filler, Volume Deficiency of the Midface
An Interventional Study to Evaluate the Safety and Performance of Crosslinked Hyaluronic Acid Hydrogel
The aim of this interventional, pre-market, double- blinded, controlled, two stages study is to evaluate the performance and safety of Crosslinked Hyaluronic Acid (CLHA) Hydrogel (with and without Lidocaine) for the Treatment of…
- Trial name
- NCT05853224
- Testing
- Crosslinked Hyaluronic Acid (CLHA) Hydrogel with and without Lidocaine
- Where
- Italy
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Biopolimeri Srl
Breast Implant; Complications, Breast Implantation; Methods, Safety and Performance
Safety and Performance of Motiva® Sizers
The Motiva® Sizer clinical study is a four-year, multicenter, post-marketing, and cohort study, designed to confirm the safety and performance of Motiva® Sizer in breast augmentation or reconstruction procedures.
- Conditions
- Breast Implant; Complications, Breast Implantation; Methods, Safety and Performance, Mammaplasty, Breast Reconstruction
- Trial name
- NCT06274736
- Testing
- Motiva Sizer
- Where
- Costa Rica
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Establishment Labs
Encephalitis
Immunogenicity of a Live Attenuated Chimeric JE Vaccine (IMOJEV) as a Booster Dose in Thai Children Primed With CD.JEVAX
This study was undertaken to assess the immunogenicity and safety of a booster dose of a live attenuated chimeric Japanese Encephalitis vaccine (JE-CV) after primary vaccination with SA14-14-2 in Thai children aged 1 to <5 years.
- Trial name
- NCT02526550
- Testing
- Live attenuated chimeric Japanese Encephalitis vaccine, Inactivated Hepatitis A vaccine
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Fertility, Fertility, Male
Plan A Occlusion and Reversal System Feasibility Study
Prospective, multicenter, single-arm, open label, interventional clinical trial investigating the safety and effectiveness of the Plan A Male Contraceptive System to occlude the vas deferens to block the passage of sperm and then…
- Conditions
- Fertility, Fertility, Male, Healthy Male Adults
- Trial name
- NCT07361120
- Testing
- Occlusion System
- Where
- 3 sites in Australia, Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Next Life Sciences
Healthy
Evaluation on Immunogenicity and Safety Profile of Trivalent OPV (tOPV Bio Farma)
The objective of this study is to compare the antibody response 30 days after two doses of t OPV
- Trial name
- NCT02093273
- Testing
- tOPV pilot batch, tOPV commercial batch
- Where
- 4 sites in Indonesia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- PT Bio Farma
Skin Resurfacing
A Phase 4 Clinical Study to Investigate the Effectiveness and Safety of Skin Resurfacing
This study is a prospective, post-marketing (Phase 4) non-registrational single-arm, open-label, multicenter study.
- Trial name
- NCT07214272
- Testing
- Fraxel® FTX Laser System
- Where
- 5 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Patient Safety
Transfer of Standard Operating Procedures in Anesthesiology
Patients safety and high Quality Performance built up the centre of anesthesiology. Standard operating procedures based on the Helsinki declaration may help to increase the Patient safety and decreased adverse Events or…
- Trial name
- QUALI-II (NCT04800796)
- Testing
- Audiovisual
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Obesity
POSE2.0 With GLP-1 Agonist for Obesity Management
Determine the effect on weight loss and obesity-related comorbidities in patients receiving the POSE 2.0 procedure with sequential use of Liraglutide at 6 months compared to those receiving Liraglutide and then undergoing the…
- Trial name
- NCT05705388
- Testing
- POSE2.0 Endoscopic Gastric Remodeling, Liraglutide injection
- Where
- United Arab Emirates
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Emirates Health Services (EHS)
Respiratory Disease
HDDO-1801 Intervention Trial
A randomized, open-label, single-dose, 3-period, 6-sequence, 3-way crossover study
- Trial name
- NCT04097951
- Testing
- Combinations
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hyundai Pharmaceutical Co., LTD.
Healthy Participants
A Trial Investigating Lu AF82422 in Healthy Chinese and Caucasian Adults
The main goals of this trial are to learn more about a) the safety and tolerability of Lu AF82422 (any new or worsening medical issues the participants have with treatment), b) the immunogenicity of Lu AF82422 (the potential for…
- Trial name
- NCT06258720
- Testing
- Lu AF82422
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Health Behavior
Student Behavior in School Accident Precautions
Accidents are an important public health problem due to temporary or permanent disability and deaths. Injuries are among the most important causes of death and lifelong disability between the ages of 5-14.
- Trial name
- NCT05576987
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Healthy Adults
Efficacy and Safety of Repetitive Transcranial Magnetic Stimulation and Expressive Writing for Post-Traumatic Stress
The goal of this clinical trial is to learn if a combined treatment using repetitive transcranial magnetic stimulation (rTMS) and expressive writing works to reduce symptoms of post-traumatic stress in adults.
- Trial name
- NCT07567261
- Testing
- Repetitive Transcranial Magnetic Stimulation, Expressive writing
- Where
- 2 sites in Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Servicio Canario de Salud
Pain, Postoperative, Orthopedic Procedures
A Randomized, Open-Label, Single-Dose, Small Study to Evaluate the Safety and Effectiveness of Hydromorphone in Patients With Short Term, Moderate to Severe Postoperative Pain
The purpose of this small study was to investigate the safety and effectiveness of OROS hydromorphone HCI for the treatment of short-term, moderate to severe postoperative pain following total knee replacement surgery.
- Conditions
- Pain, Postoperative, Orthopedic Procedures, Analgesia
- Trial name
- NCT00411307
- Testing
- OROS hydromorphone HCI
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alza Corporation, DE, USA
Medical Device, Medical Device Performance
Clinical Evaluation of an Airborne Pathogen Containment Device: Randomized Open-label Equivalence Trial During Endotracheal Intubation
The aim of this study is to test a bubble-like dome (made of clear plastic) being placed over patients' heads during surgery as a tool to prevent the spread of germs through the air in hospitals.
- Conditions
- Medical Device, Medical Device Performance, Aerosol Generating Procedure
- Trial name
- NCT06968377
- Testing
- A novel airborne pathogen containment device.
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Elective Surgical Procedure
Pilot Study to Assess the Efficacy and Safety of the Lubo Cervical Collar
The Lubo cervical collar is a device that simultaneously maintains cervical spine control and keeps an open airway in a non-invasive manner.
- Trial name
- NCT00355173
- Testing
- Lubo cervical collar
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Cirrhosis, Asthma
A Pilot Study of Mirabegron and Montelukast in Cirrhotic Patients
This study was a prospective, interventional, pilot clinical study conducted over 3 months on cirrhotic patients with overactive bladder and asthma, evaluating the real-world applicability of selected PBPK-guided dosing regimens.
- Trial name
- NCT07533565
- Testing
- Mirabegron 100 mg, Mirabegron 50mg, mirabegron 25 mg
- Where
- Egypt
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University