Clinical trials: Saliva
Nursing Caries
Effect of Laughter Yoga on Mental Symptoms Frequency and Level of Saliva Cortisol
The aim of this study is to evaluate the effect of laughter yoga on mental symptom frequency and salivary cortisol level among the 1st Year Nursing Students.
- Trial name
- NCT03814265
- Testing
- Laughter yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ankara University
Head and Neck Squamous Cell Carcinoma
Liquid Biopsy of Head and Neck Cancer Patients in Blood and Saliva
Prospective study for therapy monitoring of locally advanced and metastatic head and neck cancer patients by detection of circulating tumor nucleic acids in peripheral blood and saliva
- Trial name
- KOHACIN (NCT05122507)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Technical University of Munich
SARS-CoV2 Infection
The School SPIT Study - Elementary Schools in High COVID-19 Incidence Regions
This study will conduct an evaluation of a program that is being implemented SickKids / Toronto Public Health that provides take-home saliva testing kits in schools.
- Trial name
- NCT05055492
- Testing
- Take home saliva kits
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Hydrocortisone
Association Between Cortisol, Cortisone, Cotinine, Nicotine, Caffeine, Melatonin Levels in Hair, Serum, Urine, Saliva and Chronic Stress
The investigators aim to investigate the association between hair, serum, urine and saliva to measure cortisol, cortisone, cotinine, nicotine, melatonin and caffeine.
- Trial name
- NCT02403921
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Blood Pressure Regulation
The Effects of Nitrate-Rich Mouthwash on Vascular Tone
High blood pressure (hypertension) is a major risk factor for cardiovascular disease. One important contributing factor to high blood pressure is reduced availability of nitric oxide (NO).
- Trial name
- NITRATONE (NCT07602764)
- Testing
- Nitrate-rich mouth rinse, Nitrate-rich drink
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Breast Neoplasms, Ovarian Neoplasms
Ascertainment of Peripheral Blood or Saliva Samples for Genetic Epidemiology Studies of Familial Cancers
The purpose of this study is to better understand the genetic causes of cancer and the inherited tendency to develop cancer. To accomplish this, blood specimens and/or saliva samples and/or tumor and normal tissue blocks from…
- Conditions
- Breast Neoplasms, Ovarian Neoplasms, Colonic Neoplasms, Prostatic Neoplasms
- Trial name
- NCT00579163
- Where
- United States
- Volunteers
- 992 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Inflammatory Response, Periodontitis
Saliva Irisin Level is Higher and Related With Interleukin 6 in Generalized Periodontitis
Irisin is novel adipomyokine known as a mediator of physical activity that produced mainly by skeletal muscle and adipose tissues.
- Trial name
- NCT05474820
- Testing
- Samples collection and ELISA analyses, Evaluating periodontal paramètres
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Burning Mouth Syndrome
Opiorphin Levels in Fluids of Burning Mouth Syndrome Patients (OPIODYN)
If epidemiological studies indicate relatively low prevalence reported in the general population, idiopathic burning mouth syndrome (BMS) is a common condition among certain groups of the population: 30% of menopausal women…
- Trial name
- OPIODYN (NCT02686359)
- Testing
- sample
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cervical Cancer, Tobacco Use
Smoking Cessation for Cervical Cancer Survivors
The goal of this research study is to compare a program called Motivation And Problem-Solving (MAPS) to the standard treatment to help participants with a history of cervical cancer or high-grade cervical dysplasia quit smoking.
- Conditions
- Cervical Cancer, Tobacco Use, Smoking Cessation
- Trial name
- NCT02157610
- Testing
- Self-Help Materials, Nicotine Patch, REDCap
- Where
- 3 sites in United States
- Volunteers
- 202 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Heart Failure, Periodontitis
Periodontitis Treatment and Heart Failure
Heart failure (HF) is a rapidly growing public health issue affecting more than 40 million individuals globally; while gum disease with bone loss affects 50% of people in general.
- Trial name
- NCT07036289
- Testing
- Mechanical Treatment
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Taubate
Healthy
Collection of Dental Plaque and Saliva for Studies of Bacterial Colonization of Teeth
This study will explore how bacteria colonize human teeth and how this process changes over the lifetime of individuals. It will include an investigation of transmission of bacteria that initiate colonization between adults and…
- Trial name
- NCT00098267
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Xerostomia
Artificial Saliva Containing Cumin and Ginger Extract in Head and Neck Cancer Patients With Xerostomia
The objectives of this study are to evaluate efficacy and safety of artificial saliva containing cumin and ginger extract in head and neck cancer patients with xerostomia.
- Trial name
- NCT05872464
- Testing
- Artificial saliva containing cumin and ginger extract
- Volunteers
- 52 people
- Sponsor
- Chulalongkorn University
SARS-CoV-2, COVID-19
The Efficacy of Pre-procedural Mouth Rinses on COVID-19 Saliva Viral Load
Preoperative antiseptic mouth rinses have been widely used as a standard protocol before routine dental treatment reduces oral microorganism counts.
- Conditions
- SARS-CoV-2, COVID-19, Mouthwashes, Viral Load
- Trial name
- NCT04721457
- Testing
- Distilled Water, 1% Povidone Iodine (PVP-I), 1.5% Hydrogen Peroxide (H2O2)
- Where
- Saudi Arabia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Xerostomia
A Study of Patients With Dry Mouth and Sticky Saliva During Radiotherapy
The purpose of this study is to evaluate the clinical safety and effectiveness of Visco-ease dry mouth spray for the treatment of Radiotherapy Induced Xerostomia (RIX) in head and neck cancer patients.
- Trial name
- NCT02687087
- Testing
- Visco-ease
- Where
- United Kingdom
- Volunteers
- 44 people
- Sponsor
- NHS Greater Glasgow and Clyde
Healthy Volunteers
Epidemiology of Human Cytomegalovirus Excretion in the Saliva of Children Attending Nursery in France
Direct DNA amplification, viral isolation and specific antibody measurement in saliva from children attending nursery in France Sample collection will be done by the pediatrician the nurse, or one of the authorized investigators…
- Trial name
- CrèchMV (NCT01704222)
- Where
- France
- Volunteers
- 2,001 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Oral Health, Parkinson Disease
Preliminary Study of the Quality of the Oral Flora in Parkinson's Patients
This is a prospective interventional clinical study whose main objective is to determine the impact of oral hygiene guidance on the oral health status of patients with Parkinson disease
- Trial name
- PARKIDENT (NCT03827551)
- Testing
- Delivery of oral hygiene advices
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Bordeaux
Depressive Disorder
The Antidepressant Effect of Repetitive Transcranial Magnetic Stimulation (rTMS)Compared to ECT
The aim of the present study is to compare the antidepressant effect of electroconvulsive therapy ( ECT) with that of low frequency repetitive transcranial magnetic stimulation of the right prefrontal cortex.
- Trial name
- NCT00299403
- Testing
- Right prefrontal lowfrequency ( 1 hz) rTMS., Electroconvulsive therapy (ECT)
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Older Adults Without Any Specific Clinical Condition, Autonomic Nervous System Imbalance
Effects of Transcutaneous Vagus Nerve Stimulation in Older Adults
The autonomic nervous system consists of two branches, the sympathetic and the parasympathetic, which must work in balance. Its functioning can be measured indirectly by heart rate variability, which is the time between…
- Conditions
- Older Adults Without Any Specific Clinical Condition, Autonomic Nervous System Imbalance, Transcutaneous Vagus Nerve Stimulation
- Trial name
- tVNS_older (NCT07292623)
- Testing
- Active location tVNS
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade da Coruña
Saliva Altered, Taste, Altered
Astringency and Oral Health
The perception of astringency is thought to involve the interaction between tannins and salivary proteins. However, the mechanisms underlying this interaction are poorly understood.
- Trial name
- NCT05819073
- Testing
- Plain water, CPE
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Chronic Kidney Disease
Phosphate Binding of Chitosan Chewing Gum in Patients With Chronic Kidney Disease (CKD)
To determine the amount of phosphate recovered into 2 strengths of K2CG chewing gum in a modified formulation (with or without an extender) added to the gum core, in comparison to matching placebo gums.
- Trial name
- NCT01341691
- Testing
- chewing gum
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Denver Nephrologists, P.C.