Clinical trials: Salmonella Septicemia
Bloodstream Infection, Health Care Utilization
Health Itinerary of Young Children With Suspected Bloodstream Infection in Kisantu General Referral Hospital, DR Congo
Bloodstream infections are frequent in children admitted to the hospital for severe febrile illness in sub-Saharan Africa.Ongoing blood culture surveillance at Kisantu Hospital showed non-typhoidal Salmonella (NTS) as the first…
- Conditions
- Bloodstream Infection, Health Care Utilization, Malaria,Falciparum, Salmonella Infection Non-Typhoid
- Trial name
- HIT BSI (NCT04289688)
- Where
- Democratic Republic of the Congo
- Volunteers
- 784 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Salmonella Septicemia, Salmonella Infections
IDIS Project Work Package 2: Establishing a Biobank at ITM and Collaborating Centres
The IDIS study aims to develop a new rapid diagnostic test for invasive salmonellosis using samples (blood, urine) collected from patients with fever and healthy controls at the Institute of Tropical Medicine (ITM) and…
- Conditions
- Salmonella Septicemia, Salmonella Infections, Fever, Blood Stream Infections
- Trial name
- IDIS (NCT02689193)
- Testing
- Blood sampling
- Where
- 3 sites in Belgium, Cambodia and 1 more
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Bloodstream Infection, Salmonella Bacteremia
Clinical Decision Support in Non-typhoidal Salmonella Bloodstream Infections in Children
In sub-Saharan Africa, non-typhoidal Salmonella (NTS) are a frequent cause of bloodstream infection, display high levels of antibiotic resistance and have a high case fatality rate (15%).
- Conditions
- Bloodstream Infection, Salmonella Bacteremia, Malaria,Falciparum, Severe Malaria
- Trial name
- DeNTS (NCT04473768)
- Where
- Belgium
- Volunteers
- 1,880 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Salmonella Infections, Infection of Bloodstream
Reservoir of Invasive Salmonellosis in Children, DRC
Bloodstream infections caused by non-typhoid Salmonella (NTS) are a major killing disease in Sub-Saharan Africa. Despite the high case fatality rate, the main reservoir -human, zoonotic or environmental- for invasive NTS rests…
- Trial name
- NCT03073707
- Testing
- Sample collection
- Where
- Democratic Republic of the Congo
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Blood-stream Infections, Salmonella Infection Non-Typhoid
Treating Non-typhoidal Salmonella Bloodstream Infections in Children Under Five in DR Congo: a Cohort Study
With this study the researchers aim to provide observational data on the treatment efficacy of currently used antibiotic treatment regimens for NTS BSI in hospital-admitted children.
- Trial name
- TreNTS (NCT04850677)
- Testing
- Observational Cohort
- Where
- Democratic Republic of the Congo
- Volunteers
- 1,884 people
- Sponsor
- Institute of Tropical Medicine, Belgium