Clinical trials: Sarcopenia, pill or tablet or capsule or oral, open to volunteers
Colorectal Cancer, Colorectal Neoplasms
Resistance vs Aerobic Prehabilitation Before Colorectal Cancer Surgery
The goal of this clinical trial is to learn which type of exercise before surgery best reduces complications after colorectal surgery in adults with colorectal cancer or precancerous lesions.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Postoperative Complications
- Trial name
- NCT07896174
- Testing
- Resistance Training Prehabilitation, Aerobic Training Prehabilitation, Standard Trimodal Care
- Where
- Hungary
- Volunteers
- 480 people
- Sponsor
- Semmelweis University
Sarcopenia
Clinical Intervention of Idecalcitol Combined With Whey Protein Powder and Exercise for Sarcopenia
This clinical trial is a multicenter, single-blind, prospective, randomized controlled clinical application study. Subjects who met the trial criteria and signed the informed consent form were randomly divided into a control…
- Trial name
- NCT06537115
- Testing
- exercise, whey protein powder, Eldecalcitol
- Where
- 5 sites in China
- Volunteers
- 450 people
- Sponsor
- Zhejiang Provincial People's Hospital
The Association Between Sarcopenia and the Strength of Peripheral and Respiratory Muscles in Elderly Individuals, Cardiovascular Diseases
The Association Between Sarcopenia and the Strength of Peripheral and Respiratory Muscles in Elderly Individuals
Population aging is a significant global trend, with projections indicating that by 2050, 1 in 6 individuals worldwide will be over 65 years old, compared to 1 in 11 in 2019.
- Conditions
- The Association Between Sarcopenia and the Strength of Peripheral and Respiratory Muscles in Elderly Individuals, Cardiovascular Diseases, Diabetes Mellitus, Hypertension
- Trial name
- NCT06756399
- Testing
- Questionnare, hand grip and respiratory muscle strength
- Volunteers
- 100 people
- Sponsor
- Biruni University
Head and Neck Squamous Cell Carcinoma, Locally Advanced Rectal Cancer
GALENOS 1 in Head and Neck, Lung, and Rectal Cancer Patients
GALENOS 1 is a prospective observational study designed to explore longitudinal changes in nutritional status and body composition in patients with head and neck squamous cell carcinoma, locally advanced rectal cancer, and lung…
- Conditions
- Head and Neck Squamous Cell Carcinoma, Locally Advanced Rectal Cancer, Lung Cancer
- Trial name
- GALENOS 1 (NCT07511413)
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Nutritional Deficiency, Gastrointestinal Cancers
A Randomized, Double-blind, Placebo-controlled, Prospective, Multi-center Trial Evaluating the Improvement of Nutritional Status and Sarcopenia With Silkworm Pupa Tablets in Patients With Malignancies
This is a randomized, double-blind, placebo-controlled, parallel-group, prospective, multi-center clinical trial, to evaluate the efficacy of silkworm pupa tablets in improving nutritional status and sarcopenia in patients with…
- Conditions
- Nutritional Deficiency, Gastrointestinal Cancers, Sarcopenia
- Trial name
- NCT07554807
- Testing
- Silkworm pupa tablets
- Where
- 4 sites in China
- Volunteers
- 480 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Obesity and Obesity-related Medical Conditions, Diabetes
Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)
The purpose of this research study is to validate (check the accuracy of) laboratory assays, intravenous catheter insertion, and equipment or devices and their reproducibility, which is necessary to perform high quality research…
- Conditions
- Obesity and Obesity-related Medical Conditions, Diabetes, Atherosclerotic Disease, Heart Failure
- Trial name
- VALD (NCT07083557)
- Testing
- Endothelial cell collection
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bettina Mittendorfer
Sarcopenia, Possible Sarcopenia
HB05P on Muscle Health
The purpose of this pilot study is to evaluate whether HB05P, a health functional food ingredient containing pasteurized Akkermansia muciniphila HB05, improves muscle strength, and to evaluate its safety.
- Trial name
- NCT07749118
- Testing
- HB05P
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Lymphoblastic Leukemia, Cancer Survivors
Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors
This will be a randomized, placebo-controlled trial with a 2x2 factorial design testing the effects of an NAD+ precursor (NR) and exercise on skeletal muscle quality and VO2max in AYA HCT survivors.
- Conditions
- Lymphoblastic Leukemia, Cancer Survivors, Aplastic Anemia, Myelodysplastic Syndromes
- Trial name
- IAMFIT (NCT05194397)
- Testing
- Nicotinamide Riboside, Exercise Intervention
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Children's Hospital of Philadelphia
Melanoma
Exercise and Nutritional Intervention in Patients With Melanoma Receiving Immunotherapy
The purpose of this randomized study is to evaluate whether a six-month program of structured resistance exercise combined with individualized nutritional support can preserve or improve skeletal muscle mass and muscle quality in…
- Trial name
- MEL-FIT-IO (NCT07761871)
- Testing
- Structured Resistance Exercise, Individualized Nutritional Support
- Where
- Slovenia
- Volunteers
- 40 people
- Sponsor
- Institute of Oncology Ljubljana
Sarcopenia in Elderly, Frailty at Older Adults
Exergaming-based Sitting Tai Chi for Sarcopenia and/or Frailty
This randomized controlled trial will evaluate the effects of an exergaming-based sitting Tai Chi program on muscle strength, physical function, cognition, and psychosocial outcomes in older adults living in residential care…
- Trial name
- NCT07616219
- Testing
- Exergaming-based sitting Tai Chi, General health education
- Where
- Hong Kong
- Volunteers
- 152 people
- Sponsor
- Hong Kong Metropolitan University
Sarcopenia
Huangjing Yangji Formula Combined With Resistance Training for Sarcopenia
The goal of this clinical trial is to learn if a traditional Chinese medicine formula called "Huangjing Yangji Formula," combined with elastic band resistance training, works better than exercise alone to improve physical…
- Trial name
- NCT07321535
- Testing
- Huangjing Yangji Formula Granules, Standardized Elastic Band Resistance Training Program
- Where
- 3 sites in China
- Volunteers
- 106 people
- Sponsor
- Wangjing Hospital, China Academy of Chinese Medical Sciences
Muscle Atrophy, Age-Related Sarcopenia
Impacts of Mechanistic Target of Rapamycin (mTOR) Inhibition on Aged Human Muscle (Rapamune)
As people age, muscle mass and function is lost and exercise training is an important way to reduce the effects of this and remain independent.
- Trial name
- Rapamune (NCT05414292)
- Testing
- Rapamune (sirolimus) 1Mg Tablet, Unilateral resistance exercise training
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Chronic Kidney Disease, Sarcopenia
Sarcopenia in Chronic Kidney Disease (CKD) Patients
Sarcopenia, or loss of muscle and strength is common in patients with poor kidney function. Although a high protein diet is generally recommended for sarcopenia, patients with poor kidney function are advised to follow a…
- Trial name
- BOOST_CKD (NCT07437053)
- Testing
- Valine, EEA
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Head &Amp;Amp; Neck Squamous Cell Carcinoma
The FORCE Trial Pilot: Fish Oil-enriched Nutrition for Radiotherapy in Cancer of the hEad and Neck
en-label, proof-of-concept study designed to evaluate the feasibility, safety, and acceptability of a prophylactic fish oil-enriched nutritional supplement (Fresubin Supportan) in patients with head and neck cancer (HNC)…
- Trial name
- FORCE (NCT07180576)
- Testing
- Nutrition counseling, Fresubin Supportan
- Volunteers
- 15 people
- Sponsor
- Anna Arthur, PhD
PDAC, Pancreas Adenocarcinoma (MSI-H)
Targeted Nutritional Intervention (HMB, Arginine, Glutamine) in Patients With Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDAC) is frequently associated with cancer cachexia, a condition characterized by progressive loss of skeletal muscle mass and strength driven by systemic inflammation.
- Trial name
- NUTRI-MYO (NCT07883161)
- Testing
- HMB / L-Arginine / L-Glutamine oral nutritional mixture, Standard Dietary Counseling
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Sarcopenia
Clinical Study of TJ0113 Capsule in the Treatment of Patients With Sarcopenia
This study is a randomized, double-blind, multicenter, placebo parallel-controlled Phase II clinical study designed to evaluate the clinical efficacy and safety of TJ0113 Capsule in patients with sarcopenia.
- Trial name
- NCT07620938
- Testing
- TJ0113
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Hangzhou PhecdaMed Co., Ltd.
Sarcopenia in Elderly, Frailty
Safety and Efficacy of Isomyosamine in Reducing Inflammation and Treating Muscle Loss in Older Adults After Hip or Thigh Bone Fractures
This Phase II clinical study investigates the safety and effectiveness of a new drug, Isomyosamine, in patients with sarcopenia or frailty, conditions associated with aging and muscle weakness.
- Conditions
- Sarcopenia in Elderly, Frailty, Frailty/Sarcopenia, Frailty in Older Adults
- Trial name
- NCT06942182
- Testing
- Isomyosamine 250mg
- Volunteers
- 60 people
- Sponsor
- TNF Pharmaceuticals, Inc.
Bone Sarcoma, Soft Tissue Sarcoma
Preoperative Immunonutrition in Patients With Bone and Soft Tissue Sarcomas
This study will evaluate whether a short nutritional intervention before surgery can improve recovery in patients with bone and soft tissue sarcomas.
- Conditions
- Bone Sarcoma, Soft Tissue Sarcoma, Sarcopenia, Malnutrition
- Trial name
- NCT07609329
- Testing
- Forticare Advanced oral nutritional supplement
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Sarcopenia, Anemia Associated With Chronic Kidney Disease (CKD)
Hypoxia-inducible Factor Prolyl Hydroxylase Inhibitors on Sarcopenia in Hemodialysis Patients
Sarcopenia, abbreviated as muscle loss, is a prevalent complication among patients with chronic kidney disease (CKD), particularly those with end - stage renal disease (ESRD). It significantly impacts patients' quality of life.
- Conditions
- Sarcopenia, Anemia Associated With Chronic Kidney Disease (CKD), Dialysis Patients
- Trial name
- HIF-PHI (NCT07162090)
- Testing
- Roxadustat, Recombinant human erythropoietin (EPO)
- Volunteers
- 60 people
- Sponsor
- Tianjin Medical University General Hospital
Sarcopenia
Magnesium Supplementation as a Nutritional Intervention in Sarcopenia
Sarcopenia is a progressive condition common in older adults and is characterized by loss of muscle strength, muscle mass, and physical performance.
- Trial name
- SARCOMAG (NCT07567963)
- Testing
- Citrate Magnesium Supplementation
- Where
- Portugal
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Saúde - Universidade do Algarve