Clinical trials: Sars-CoV-2
SARS-CoV Infection, Vitamin D Deficiency
Influence of Military Preventive Policy for reCruit Training on COVID-19 Seroconversion
This study is intended to address the association between vitamin D status and seroconversion to SARS-CoV-2 in healthy young adults.
- Conditions
- SARS-CoV Infection, Vitamin D Deficiency, Covid19, Acute Respiratory Tract Infection
- Trial name
- IMPACTCOVID (NCT04476680)
- Testing
- Vitamin D
- Where
- 2 sites in United Kingdom
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Royal Centre for Defence Medicine
COVID-19 Pandemic
Motivation, Syringe Exchange, and COVID-19
People who inject drugs (PWIDs) are highly vulnerable to SARS-CoV-2 infection and to the disease caused by SARS-CoV-2, coronavirus disease 2019 (COVID-19), however, rates of SARS-CoV-2 testing and vaccination uptake -vital to…
- Trial name
- NCT05534061
- Testing
- Connect2Test
- Where
- United States
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- University of Oregon
SARS-CoV-2 Virus Infection
COV-COMPARE Immunogenicity of Vaccine VLA2001 Compared to AZD1222
This is a multicentre, randomized, observer-blind, active-controlled, superiority, study in adults to compare the immunogenicity of VLA2001 to AZD1222 in terms of GMT of SARS-CoV-2-specific neutralising antibodies.
- Trial name
- COV-COMPARE (NCT04864561)
- Testing
- VLA2001, AZD1222, VLA2001 - adolescent part
- Where
- 31 sites in United Kingdom
- Volunteers
- 4,034 people, healthy volunteers welcome
- Sponsor
- Valneva Austria GmbH
COVID-19, Long Covid
"Long COVID-19" on the Human Brain
Over one million Canadians have been infected by COVID-19. Many people who have been infected by COVID-19 experience negative mental symptoms, such as "brain fog" and fatigue.
- Conditions
- COVID-19, Long Covid, Post Acute Sequelae of COVID-19
- Trial name
- NCT05433324
- Testing
- MRI and PET Scans
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
SARS COV-2 IgG Levels on Health Workers
SARS Cov_2 Incidence of Healthy Health Workers
Since the severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) first emerged in Wuhan, China, on 12 December 2019, it has spread rapidly across the world and developed into a pandemic.
- Trial name
- NCT04845880
- Testing
- Spike protein (S) or the nucleocapsid (N) of SARS-CoV-2
- Where
- Turkey (Türkiye)
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Baskent University
SARS-CoV-2 Infection, COVID-19
Study to Evaluate the Safety, Tolerability, and Immunogenicity of an RNA Vaccine Candidate Against COVID-19 in Healthy Japanese Adults
This is a Phase 1/2, randomized, placebo-controlled, and observer-blind study in healthy Japanese adults. The study will evaluate the safety, tolerability, and immunogenicity of the SARS-CoV-2 RNA vaccine candidate against…
- Trial name
- NCT04588480
- Testing
- BNT162b2
- Where
- 2 sites in Japan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- BioNTech SE
COVID-19, Healthy Volunteers
Study of the Kinetics of Antibodies Against COVID-19 (SARS-CoV-2) and of Cellular Subpopulations of the Immune System
Determination of both the degree and duration of the immunity provided after receiving the BNT162b2 vaccine against SARS-Cov-2.
- Conditions
- COVID-19, Healthy Volunteers, Chronic Disease, Hematological Malignancies
- Trial name
- NCT04743388
- Testing
- BNT162b2, Other vaccine against SARS-Cov-2
- Where
- Greece
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
COVID-19
Safety of an Inactivated SARS-CoV-2 Vaccine for Prevention of COVID-19 in Adults
This study is a multi-center and open design, phase Ⅳ clinical trial of an inactivated SARS-CoV-2 vaccine (CoronaVac) manufactured by Sinovac Research and Development Co., Ltd.The purpose of this study is to evaluate the safety…
- Trial name
- NCT04911790
- Testing
- Experimental Group
- Where
- China
- Volunteers
- 131,650 people, healthy volunteers welcome
- Sponsor
- Sinovac Research and Development Co., Ltd.
COVID-19, ARDS, Human
The Critical Care Response to the COVID-19 Pandemic in Madrid
Description of the adaptation of ICUs in the region of Madrid to que surge in demand of critical care due to COVID-19
- Trial name
- Tetrix (NCT04393324)
- Where
- Spain
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Hospital San Carlos, Madrid
COVID-19, Molecular Sequence Variation
COVID-19 Genomic Sequencing for Nosocomial Outbreak Investigations
This is a tertiary care hospital-based prospective molecular epidemiology study in Montreal, Canada. When nosocomial transmission was suspected by local infection control teams' investigations, SARS-CoV-2 viral genomic sequencing…
- Conditions
- COVID-19, Molecular Sequence Variation, Nosocomial Infection
- Trial name
- NOSO-COVID (NCT05411562)
- Testing
- SARS-CoV-2 genomic sequencing
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
COVID-19
A Phase II Clinical Trial to Evaluate the Recombinant Vaccine for COVID-19 (Adenovirus Vector)
This is a phase II, randomised, double-blinded and placebo-controlled clinical trial in healthy adults above 18 years of age. This clinical trial is designed to evaluate the immunogenicity and safety of Ad5-nCoV which encodes for…
- Trial name
- CTII-nCoV (NCT04341389)
- Testing
- Recombinant novel coronavirus vaccine (Adenovirus type 5 vector)
- Where
- China
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- Institute of Biotechnology, Academy of Military Medical Sciences, PLA of China
Sars-CoV2, Breastmilk
Is COVID-19 Transmitted Through Human Milk? Implications for Breastfeeding and Human Milk Banking-Study 1b
The Canadian Paediatric Society recommends breastfeeding during COVID-19 infection. Human milk is the best form of infant nutrition providing significant protection against many illnesses for term and preterm infants.
- Trial name
- NCT04453982
- Testing
- Human milk donors
- Where
- Canada
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Deborah O'Connor
Type 2 Diabetes
Technology-enabled Collaborative Care for Diabetes Management During COVID-19
The overall goal of this research program is to evaluate the effectiveness of a Technology-Enabled Collaborative Care program. In this study, we examine the feasibility of such a program, called the Technology-Enabled…
- Trial name
- NCT04607915
- Testing
- Intervention for TECC Model
- Where
- Canada
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
COVID-19 Respiratory Infection
Spa Rehabilitation, Antioxidant and Bioenergetic Supportive Treatment of Patients With Post-Covid-19 Syndrome
Our hypothesis - that 21 days of mountain spa rehabilitation with ubiquinol supplementation could to accelerate regeneration of patients with post-COVID-19 syndrome, based on the improving platelet mitochondrial bioenergetic…
- Trial name
- SpaCOVID (NCT05178225)
- Testing
- ubiquinol (reduced coenzyme Q10), mountain spa rehabilitation, 2x14 ml of peripheral blood collected in a tube with anticoagulant
- Where
- Slovakia
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Comenius University
Lung Function Decreased, Obesity
Lung Functions in Menopausal Obese Women After COVID 19 Recovery
The COVID-19 pandemic has presented considerable challenges to global health services and dictates almost every aspect of medical practice and policy.
- Conditions
- Lung Function Decreased, Obesity, Menopause, Covid19
- Trial name
- NCT05008991
- Testing
- Spirometry
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Badr University
COVID19- Infection with SARS-CoV-2 Virus, SARS-CoV-2 Positive Patients
Impact of the Elevation Training Mask in CrossFit® Post-SARS-CoV-2 Infection.
Introduction: The Elevation Training Mask (ETM) could restore respiratory or hematological organic damages from the acute or post-infection phase of severe acute respiratory syndrome coronavirus 2 (SARSCoV2) because it would…
- Conditions
- COVID19- Infection with SARS-CoV-2 Virus, SARS-CoV-2 Positive Patients, COVID-19 Pulmonary Complications, SARS-CoV-2 Infection (Symptomatic)
- Trial name
- ETMEXCOVID (NCT06806124)
- Testing
- Elevation Training Mask
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Valladolid
COVID-19, Post-Acute COVID-19
Genetic Risk Factors for Multi-system Inflammatory Syndrome in Children and Pediatric Post COVID Condition
We will perform Whole Exome Sequencing on DNA from saliva. We will include: Children with a history of MIS-C; children with post-COVID condition; and controls in order to identify rare, high impact genetic variants in…
- Conditions
- COVID-19, Post-Acute COVID-19, Post-Acute COVID19 Syndrome, Multi-System Inflammatory Syndrome in Children
- Trial name
- GRIP (NCT05722717)
- Testing
- Saliva collection at home
- Where
- Netherlands
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
COVID-19
Antibody Responses in Contacts of COVID-19 Patients
After several cases of pneumonia with an unfamiliar etiology were observed at the end of 2019, the National Health Commission of China released more details about the epidemic in early 2020.
- Trial name
- NCT04444310
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
COVID-19 Respiratory Infection, Influenza
Exercise and COVID-19 Viral T-cell Immunity
Viruses are a major health problem for the general public and at risk populations. Normally, detection of antibody titers is the gold standard for determining the effectiveness of the immune system following natural or vaccine…
- Trial name
- VIC (NCT05019456)
- Testing
- COVID-19 Vaccine
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Post COVID-19 Condition, Somatic Symptom Disorder
MR-spectroscopy in Post-covid Condition Prior to and Following a Yoga Breathing Intervention
From a clinical perspective, we find that many patients with Post COVID condition suffer from severe and debilitating shortness of breath, while routine pulmonary investigations fail to find the cause of the problems experienced.
- Trial name
- SpeCY (NCT05946512)
- Testing
- yoga, social contact
- Where
- Austria
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
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